Research efforts focus on the development of high-performance, model-based control systems that enable safe and effective operation of processes. Energy-related applications are the target of these efforts. Recent research has focused on the development of optimal control systems for energy production from biomass, and in particular, anaerobic digestion processes. Globally stabilizing control algorithms for anaerobic digesters have been developed, that enable operation around optimal conditions. Current and future research efforts include energy from biomass applications, and also, control and optimization problems related to both upstream and downstream operations in the petroleum industry.