HR job title
- Executive Associate Dean and Associate Agency Director
- Contact Info
- 1 979 845 3306
Jayaraman, Arul Professor
Positions
- Professor, Chemical Engineering, College of Engineering
- Overview
- Publications
- Research
- Teaching
- Works By Students
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Overview
Publications
selected publications
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academic article
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Penarete-Acosta, D., Stading, R., Emerson, L., Horn, M., Chakraborty, S., Han, A., & Jayaraman, A.
(2024).
A microfluidic co-culture model for investigating colonocytes-microbiota interactions in colorectal cancer. 24(15), 3690-3703.
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Ding, Y., Yanagi, K., Yang, F., Callaway, E., Cheng, C., Hensel, M. E., ... Jayaraman, A.
(2024).
Oral supplementation of gut microbial metabolite indole-3-acetate alleviates diet-induced steatosis and inflammation in mice. eLife.
12, RP87458.
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Han, H., Davidson, L. A., Fan, Y., Landrock, K. K., Jayaraman, A., Safe, S. H., & Chapkin, R. S.
(2022).
Loss of aryl hydrocarbon receptor suppresses the response of colonic epithelial cells to IL22 signaling by upregulating SOCS3. American Journal of Physiology - Gastrointestinal and Liver Physiology.
322(1), G93-G106.
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Yang, Y., Osorio, D., Davidson, L. A., Han, H., Mullens, D. A., Jayaraman, A., ... Chapkin, R. S.
(2022).
Single-cell RNA Sequencing Reveals How the Aryl Hydrocarbon Receptor Shapes Cellular Differentiation Potency in the Mouse Colon. Cancer Prevention Research.
15(1), 17-28.
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Chapkin, R. S., Davidson, L. A., Park, H., Jin, U., Fan, Y., Cheng, Y., ... Safe, S.
(2021).
Role of the Aryl Hydrocarbon Receptor (AhR) in Mediating the Effects of Coffee in the Colon. Molecular Nutrition and Food Research.
65(20), e2100539-2100539.
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Lei, M., Jayaraman, A., Van Deventer, J. A., & Lee, K.
(2021).
Engineering Selectively Targeting Antimicrobial Peptides. Annual Review of Biomedical Engineering.
23(1), 339-357.
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Han, H., Davidson, L. A., Hensel, M., Yoon, G., Landrock, K., Allred, C., ... Chapkin, R. S.
(2021).
Loss of Aryl Hydrocarbon Receptor Promotes Colon Tumorigenesis in ApcS580/+; KrasG12D/+ Mice. Molecular Cancer Research.
19(5), 771-783.
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Wu, C., Muthyala, S., Klemashevich, C., Ufondu, A. U., Menon, R., Chen, Z., ... Sun, Y.
(2021).
Age-dependent remodeling of gut microbiome and host serum metabolome in mice. Aging.
13(5), 6330-6345.
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Park, H., Jin, U., Karki, K., Allred, C., Davidson, L. A., Chapkin, R. S., ... Safe, S.
(2021).
Hydroxylated Chalcones as Aryl Hydrocarbon Receptor Agonists: Structure-Activity Effects. TOXICOLOGICAL SCIENCES.
180(1), 148-159.
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Eshghjoo, S., Kim, D. M., Jayaraman, A., Sun, Y., & Alaniz, R. C.
(2021).
A Comprehensive High-Efficiency Protocol for Isolation, Culture, Polarization, and Glycolytic Characterization of Bone Marrow-Derived Macrophages. Journal of Visualized Experiments.
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Baranwal, G., Pilla, R., Goodlett, B. L., Coleman, A. K., Arenaz, C. M., Jayaraman, A., ... Mitchell, B. M.
(2021).
Common Metabolites in Two Different Hypertensive Mouse Models: A Serum and Urine Metabolome Study. Biomolecules.
11(9), 1387-1387.
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Han, H., Safe, S., Jayaraman, A., & Chapkin, R. S.
(2021).
Diet-Host-Microbiota Interactions Shape Aryl Hydrocarbon Receptor Ligand Production to Modulate Intestinal Homeostasis. Annual Review of Nutrition.
41(1), 455-478.
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Chen, Y., Li, J., Menon, R., Jayaraman, A., Lee, K., Huang, Y., ... Dashwood, R. H.
(2021).
Dietary spinach reshapes the gut microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics. Gut Microbes.
13(1), 1972756.
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Safe, S., Jayaraman, A., Chapkin, R. S., Howard, M., Mohankumar, K., & Shrestha, R.
(2021).
Flavonoids: structure-function and mechanisms of action and opportunities for drug development. Toxicological research.
37(2), 147-162.
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Eshghjoo, S., Jayaraman, A., Sun, Y., & Alaniz, R. C.
(2021).
Microbiota-Mediated Immune Regulation in Atherosclerosis. Molecules.
26(1), 179-179.
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Albright, V., Penarete-Acosta, D., Stack, M., Zheng, J., Marin, A., Hlushko, H., ... Sukhishvili, S. A.
(2021).
Polyphosphazenes enable durable, hemocompatible, highly efficient antibacterial coatings. Biomaterials.
268, 120586-120586.
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Lee, D., Jayaraman, A., & Kwon, J. S.
(2020).
Development of a hybrid model for a partially known intracellular signaling pathway through correction term estimation and neural network modeling. PLoS Computational Biology.
16(12), e1008472-e1008472.
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Yang, F., DeLuca, J., Menon, R., Garcia-Vilarato, E., Callaway, E., Landrock, K. K., ... Jayaraman, A.
(2020).
Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles. Microbial Cell Factories.
19(1), 219.
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Park, H., Jin, U., Karki, K., Jayaraman, A., Allred, C., Michelhaugh, S. K., ... Safe, S.
(2020).
Dopamine is an aryl hydrocarbon receptor agonist. Biochemical Journal.
477(19), 3899-3910.
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Han, H., Davidson, L. A., Fan, Y., Goldsby, J. S., Yoon, G., Jin, U., ... Chapkin, R. S.
(2020).
Loss of aryl hydrocarbon receptor potentiates FoxM1 signaling to enhance self-renewal of colonic stem and progenitor cells. EMBO Journal.
39(19), e104319.
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Kannan, P., Kotu, S. P., Pasman, H., Vaddiraju, S., Jayaraman, A., & Mannan, M. S.
(2020).
A systems-based approach for modeling of microbiologically influenced corrosion implemented using static and dynamic Bayesian networks. JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES.
65, 104108-104108.
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Lee, D., Jayaraman, A., & Kwon, J.
(2020).
Identification of cell-to-cell heterogeneity through systems engineering approaches. AIChE Journal.
66(5),
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Yang, J., Chawla, R., Rhee, K. Y., Gupta, R., Manson, M. D., Jayaraman, A., & Lele, P. P.
(2020).
Biphasic chemotaxis of Escherichia coli to the microbiota metabolite indole. Proceedings of the National Academy of Sciences of the United States of America.
117(11), 6114-6120.
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Garcia-Villatoro, E. L., DeLuca, J., Callaway, E. S., Allred, K. F., Davidson, L. A., Hensel, M. E., ... Allred, C. D.
(2020).
Effects of high-fat diet and intestinal aryl hydrocarbon receptor deletion on colon carcinogenesis. American Journal of Physiology - Gastrointestinal and Liver Physiology.
318(3), G451-G463.
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Letsinger, A. C., Menon, R., Iyer, A. R., Vellers, H. L., Granados, J. Z., Jayaraman, A., & Lightfoot, J. T.
(2020).
A High Fat/High Sugar Diet Alters the Gastrointestinal Metabolome in a Sex Dependent Manner. Metabolites.
10(10), 421-421.
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Safe, S., Jayaraman, A., & Chapkin, R. S.
(2020).
Ah receptor ligands and their impacts on gut resilience: structure-activity effects. Critical Reviews in Toxicology.
50(6), 463-473.
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Safe, S., Jin, U., Park, H., Chapkin, R. S., & Jayaraman, A.
(2020).
Aryl Hydrocarbon Receptor (AHR) Ligands as Selective AHR Modulators (SAhRMs). International Journal of Molecular Sciences.
21(18), 6654-6654.
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Hassanpour, N., Alden, N., Menon, R., Jayaraman, A., Lee, K., & Hassoun, S.
(2020).
Biological Filtering and Substrate Promiscuity Prediction for Annotating Untargeted Metabolomics. Metabolites.
10(4), 160-160.
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Park, S., Ufondu, A., Lee, K., & Jayaraman, A.
(2020).
Emerging computational tools and models for studying gut microbiota composition and function. Current Opinion in Biotechnology.
66, 301-311.
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Maiti, S., Grivas, G., Choi, K., Dai, W., Ding, Y., Acosta, D. P., Hahn, J., & Jayaraman, A.
(2020).
MODELING INTER-KINGDOM REGULATION OF INFLAMMATORY SIGNALING IN HUMAN INTESTINAL EPITHELIAL CELLS. Computers and Chemical Engineering.
140, 106954-106954.
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Orr, A. A., Yang, J., Sule, N., Chawla, R., Hull, K. G., Zhu, M., ... Tamamis, P.
(2020).
Molecular Mechanism for Attractant Signaling to DHMA by E.coli Tsr. Biophysical Journal.
118(2), 492-504.
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Han, H., Jayaraman, A., Safe, S., & Chapkin, R. S.
(2020).
Targeting the aryl hydrocarbon receptor in stem cells to improve the use of food as medicine. Current Stem Cell Reports.
6(4), 109-118.
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Lei, M., Menon, R., Manteiga, S., Alden, N., Hunt, C., Alaniz, R. C., Lee, K., & Jayaraman, A.
(2019).
Environmental Chemical Diethylhexyl Phthalate Alters Intestinal Microbiota Community Structure and Metabolite Profile in Mice. mSystems.
4(6), e00724-e00719.
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Park, H., Jin, U., Orr, A. A., Echegaray, S. P., Davidson, L. A., Allred, C. D., ... Safe, S.
(2019).
Isoflavones as Ah Receptor Agonists in Colon-Derived Cell Lines: Structure-Activity Relationships. CHEMICAL RESEARCH IN TOXICOLOGY.
32(11), 2353-2364.
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Lee, D., Jayaraman, A., & Sang-Il Kwon, J.
(2019).
Identification of a time-varying intracellular signalling model through data clustering and parameter selection: application to NF-[inline-formula removed]B signalling pathway induced by LPS in the presence of BFA. 13(4), 169-179.
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Menon, R., Fitzsimmons, B., Vanajakumari, M. U., Lee, K., & Jayaraman, A.
(2019).
Effect of Norepinephrine on Gut Bacterial Community Structure and Function. The FASEB Journal.
33(S1), 724.4-724.4.
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Wang, H., Jayaraman, A., Menon, R., Gejji, V., Karthikeyan, R., & Fernando, S.
(2019).
A non-beta-lactam antibiotic inhibitor for enterohemorrhagic Escherichia coli O104:H4. 97(9), 1285-1297.
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Kotu, S. P., Mannan, M. S., & Jayaraman, A.
(2019).
Emerging molecular techniques for studying microbial community composition and function in microbiologically influenced corrosion. International Biodeterioration and Biodegradation.
144, 104722-104722.
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Krishnan, S., Ding, Y., Saeidi, N., Choi, M., Sridharan, G. V., Sherr, D. H., ... Lee, K.
(2019).
Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages. Cell Reports.
28(12), 3285-3285.
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Ding, Y., Yanagi, K., Cheng, C., Alaniz, R. C., Lee, K., & Jayaraman, A.
(2019).
Interactions between gut microbiota and non-alcoholic liver disease: The role of microbiota-derived metabolites. Pharmacological Research.
141, 521-529.
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Lee, K., & Jayaraman, A.
(2019).
Interactions between gut microbiota and non-alcoholic liver disease: The role of microbiota-derived metabolites. Pharmacological Research.
142, 314-314.
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Abada, B., Alivio, T., Shao, Y., O'Loughlin, T. E., Klemashevich, C., Banerjee, S., Jayaraman, A., & Chu, K.
(2018).
Photodegradation of fluorotelomer carboxylic 5:3 acid and perfluorooctanoic acid using zinc oxide. Environmental Pollution.
243(Pt A), 637-644.
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Jin, U., Park, H., Li, X. i., Davidson, L. A., Allred, C., Patil, B., ... Safe, S.
(2018).
Structure-Dependent Modulation of Aryl Hydrocarbon Receptor-Mediated Activities by Flavonoids. TOXICOLOGICAL SCIENCES.
164(1), 205-217.
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DeLuca, J. A., Allred, K. F., Menon, R., Riordan, R., Weeks, B. R., Jayaraman, A., & Allred, C. D.
(2018).
Bisphenol-A alters microbiota metabolites derived from aromatic amino acids and worsens disease activity during colitis. Experimental Biology and Medicine.
243(10), 864-875.
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Olson, M. L., Jayaraman, A., & Kao, K. C.
(2018).
Relative Abundances of Candida albicans and Candida glabrata in In Vitro Coculture Biofilms Impact Biofilm Structure and Formation. 84(8), e02769-e02717.
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Lee, D., Ding, Y., Jayaraman, A., & Kwon, J. S.
(2018).
Mathematical Modeling and Parameter Estimation of Intracellular Signaling Pathway: Application to LPS-induced NF kappa B Activation and TNF alpha Production in Macrophages. Processes.
6(3), 21-21.
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Lopez-Gelston, C., Eshghjoo, S., Weeks, C., DeLeonibus, S., Jayaraman, A., Alaniz, R. C., & Chakraborty, S.
(2018).
Abstract 17311: Gut Microbiota Derived Metabolites Impact Lymphatic Inflammatory Mechanisms. Circulation.
138(Suppl_1),
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Sinkoe, A., Jayaraman, A., & Hahn, J.
(2018).
Dynamic optimal experimental design yields marginal improvement over steady-state results for computational maximisation of regulatory T-cell induction in ex vivo culture. 12(6), 241-246.
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Cheng, C., Steinmeyer, S., Jayaraman, A., & Alaniz, R.
(2018).
Gene Expression Analysis of the Effect of Microbial Tryptophan Metabolites on Tcell Differentiation. The FASEB Journal.
32(S1), 613.2-613.2.
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Krishnan, S., Ding, Y., Saedi, N., Choi, M., Sridharan, G. V., Sherr, D. H., ... Lee, K.
(2018).
Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages. Cell Reports.
23(4), 1099-1111.
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Albright, V., Xu, M., Palanisamy, A., Cheng, J., Stack, M., Zhang, B., ... Wang, H.
(2018).
Micelle-Coated, Hierarchically Structured Nanofibers with Dual-Release Capability for Accelerated Wound Healing and Infection Control. Advanced healthcare materials.
7(11), e1800132-1800132.
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Menon, R., Jani, S., Riordan, R., & Jayaraman, A.
(2018).
Serotonin Promotes Enterohemorrhagic Escherichia Coli Pathogenesis Through Altered AI2 Production by Gut Microbiota. The FASEB Journal.
32(S1), 669.11-669.11.
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Albright, V., Xu, M., Palanisamy, A., Cheng, J., Stack, M., Zhang, B., ... Wang, H.
(2018).
Skin Wound Healing: MicelleCoated, Hierarchically Structured Nanofibers with DualRelease Capability for Accelerated Wound Healing and Infection Control (Adv. Healthcare Mater. 11/2018). Advanced healthcare materials.
7(11), 1870045-1870045.
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Kohli, N., Crisp, Z., Riordan, R., Li, M., Alaniz, R. C., & Jayaraman, A.
(2018).
The microbiota metabolite indole inhibits Salmonella virulence: Involvement of the PhoPQ two-component system. PLoS ONE.
13(1), e0190613-e0190613.
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Pasupuleti, S., Sule, N., Manson, M. D., & Jayaraman, A.
(2018).
Conversion of Norepinephrine to 3,4-Dihdroxymandelic Acid in Escherichia coli Requires the QseBC Quorum-Sensing System and the FeaR Transcription Factor. Journal of Bacteriology.
200(1), e00564-e00517.
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Orr, A. A., Jayaraman, A., & Tamamis, P.
(2018).
Molecular Modeling of Chemoreceptor:Ligand Interactions. 1729, 353-372.
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Jani, S., Seely, A. L., Peabody V, G. L., Jayaraman, A., & Manson, M. D.
(2017).
Chemotaxis to self-generated AI-2 promotes biofilm formation in Escherichia coli. Microbiology (United Kingdom).
163(12), 1778-1790.
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Jin, U., Cheng, Y., Park, H., Davidson, L. A., Callaway, E. S., Chapkin, R. S., ... Safe, S.
(2017).
Short Chain Fatty Acids Enhance Aryl Hydrocarbon (Ah) Responsiveness in Mouse Colonocytes and Caco-2 Human Colon Cancer Cells. Scientific Reports.
7(1), 10163.
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Oh, J. K., Kohli, N., Zhang, Y., Min, Y., Jayaraman, A., Cisneros-Zevallos, L., & Akbulut, M.
(2016).
Nanoporous aerogel as a bacteria repelling hygienic material for healthcare environment. Nanotechnology.
27(8), 085705-085705.
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Whitfield-Cargile, C. M., Cohen, N. D., Chapkin, R. S., Weeks, B. R., Davidson, L. A., Goldsby, J. S., ... Alaniz, R. C.
(2016).
The microbiota-derived metabolite indole decreases mucosal inflammation and injury in a murine model of NSAID enteropathy. Gut Microbes.
7(3), 246-261.
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Cheng, Y., Jin, U., Allred, C. D., Jayaraman, A., Chapkin, R. S., & Safe, S.
(2015).
Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes. Drug Metabolism And Disposition.
43(10), 1536-1543.
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Oh, J. K., Perez, K., Kohli, N., Kara, V., Li, J., Min, Y., ... Akbulut, M.
(2015).
Hydrophobically-modified silica aerogels: Novel food-contact surfaces with bacterial anti-adhesion properties. FOOD CONTROL.
52, 132-141.
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Guard, B. C., Barr, J. W., Reddivari, L., Klemashevich, C., Jayaraman, A., Steiner, J. M., Vanamala, J., & Suchodolski, J. S.
(2015).
Characterization of microbial dysbiosis and metabolomic changes in dogs with acute diarrhea. PLoS ONE.
10(5), e0127259-e0127259.
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Steinmeyer, S., Lee, K., Jayaraman, A., & Alaniz, R. C.
(2015).
Microbiota metabolite regulation of host immune homeostasis: a mechanistic missing link. Current Allergy and Asthma Reports.
15(5), 24.
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Pasupuleti, S., Sule, N., Cohn, W. B., MacKenzie, D. S., Jayaraman, A., & Manson, M. D.
(2014).
Chemotaxis of Escherichia coli to norepinephrine (NE) requires conversion of NE to 3,4-dihydroxymandelic acid. Journal of Bacteriology.
196(23), 3992-4000.
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Choi, K., Ghaddar, B., Moya, C., Shi, H., Sridharan, G. V., Lee, K., & Jayaraman, A.
(2014).
Analysis of transcription factor network underlying 3T3-L1 adipocyte differentiation. PLoS ONE.
9(7), e100177-e100177.
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Jin, U., Lee, S., Sridharan, G., Lee, K., Davidson, L. A., Jayaraman, A., ... Safe, S.
(2014).
Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities. Molecular Pharmacology.
85(5), 777-788.
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Sridharan, G. V., Choi, K., Klemashevich, C., Wu, C., Prabakaran, D., Pan, L. B., ... Jayaraman, A.
(2014).
Prediction and quantification of bioactive microbiota metabolites in the mouse gut. Nature Communications.
5(1), 5492.
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Zhang, M., Yang, F., Pasupuleti, S., Oh, J. K., Kohli, N., Lee, I., ... Akbulut, M.
(2014).
Preventing adhesion of Escherichia coli O157:H7 and Salmonella Typhimurium LT2 on tomato surfaces via ultrathin polyethylene glycol film. International journal of food microbiology.
185, 73-81.
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Klemashevich, C., Wu, C., Howsmon, D., Alaniz, R. C., Lee, K., & Jayaraman, A.
(2014).
Rational identification of diet-derived postbiotics for improving intestinal microbiota function. Current Opinion in Biotechnology.
26, 85-90.
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Manteiga, S., Choi, K., Jayaraman, A., & Lee, K.
(2013).
Systems biology of adipose tissue metabolism: regulation of growth, signaling and inflammation. Wiley Interdisciplinary Reviews: Systems Biology and Medicine.
5(4), 425-447.
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Longsine-Parker, W., Wang, H., Koo, C., Kim, J., Kim, B., Jayaraman, A., & Han, A.
(2013).
Microfluidic electro-sonoporation: a multi-modal cell poration methodology through simultaneous application of electric field and ultrasonic wave. Lab on a Chip.
13(11), 2144-2152.
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Bansal, L., Nelson, R., Yang, E., Jayaraman, A., & Hahn, J.
(2013).
Experimental design of systems involving multiple fluorescent protein reporters. Chemical Engineering Science (CES).
101, 191-198.
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Huang, J., Kim, J., Ding, Y., Jayaraman, A., & Ugaz, V. M.
(2013).
Embedding synthetic microvascular networks in poly(lactic acid) substrates with rounded cross-sections for cell culture applications. PLoS ONE.
8(9), e73188-e73188.
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Bansal, T., Kim, D. N., Slininger, T., Wood, T. K., & Jayaraman, A.
(2012).
Human intestinal epithelial cell-derived molecule(s) increase enterohemorrhagic Escherichia coli virulence. FEMS Immunology and Medical Microbiology.
66(3), 399-410.
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Huang, J., Jayaraman, A., & Ugaz, V. M.
(2012).
Enzymatic Sculpting of Nanoscale and Microscale Surface Topographies. Angewandte Chemie.
124(38), 9757-9761.
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Huang, J., Jayaraman, A., & Ugaz, V. M.
(2012).
Enzymatic sculpting of nanoscale and microscale surface topographies. Angewandte Chemie International Edition.
51(38), 9619-9623.
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Sheng, L., Pu, M., Hegde, M., Zhang, Y., Jayaraman, A., & Wood, T. K.
(2012).
Interkingdom adenosine signal reduces Pseudomonas aeruginosa pathogenicity. Microb Biotechnol.
5(4), 560-572.
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Kim, J., Taylor, D., Agrawal, N., Wang, H., Kim, H., Han, A., Rege, K., & Jayaraman, A.
(2012).
A programmable microfluidic cell array for combinatorial drug screening. Lab on a Chip.
12(10), 1813-1822.
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Kim, J., Hegde, M., Kim, S. H., Wood, T. K., & Jayaraman, A.
(2012).
A microfluidic device for high throughput bacterial biofilm studies. Lab on a Chip.
12(6), 1157-1163.
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Bansal, T.
(2012).
Role for the Bacterial Signal Indole in Promoting Epithelial Cell Barrier Function. Journal of Epithelial Biology & Pharmacology.
5(1), 32-38.
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Newton, B. W., Russell, W. K., Russell, D. H., Ramaiah, S. K., & Jayaraman, A.
(2012).
Proteomic methods for biomarker discovery in a rat model of alcohol steatosis. Methods in molecular biology (Clifton, N.J.).
909, 259-277.
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Newton, B. W., Cologna, S. M., Moya, C., Russell, D. H., Russell, W. K., & Jayaraman, A.
(2011).
Proteomic analysis of 3T3-L1 adipocyte mitochondria during differentiation and enlargement. Journal of Proteome Research.
10(10), 4692-4702.
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Hegde, M., Englert, D. L., Schrock, S., Cohn, W. B., Vogt, C., Wood, T. K., Manson, M. D., & Jayaraman, A.
(2011).
Chemotaxis to the quorum-sensing signal AI-2 requires the Tsr chemoreceptor and the periplasmic LsrB AI-2-binding protein. Journal of Bacteriology.
193(3), 768-773.
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Taylor, D. J., Parsons, C. E., Han, H., Jayaraman, A., & Rege, K.
(2011).
Parallel screening of FDA-approved antineoplastic drugs for identifying sensitizers of TRAIL-induced apoptosis in cancer cells. BMC Cancer.
11(1), 470.
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Vikram, A., Jesudhasan, P. R., Jayaprakasha, G. K., Pillai, S. D., Jayaraman, A., & Patil, B. S.
(2011).
Citrus flavonoid represses Salmonella pathogenicity island 1 and motility in S. Typhimurium LT2. International journal of food microbiology.
145(1), 28-36.
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Moya, C., Huang, Z., Cheng, P., Jayaraman, A., & Hahn, J.
(2011).
Investigation of IL-6 and IL-10 signalling via mathematical modelling. 5(1), 15-26.
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Huang, Z., Moya, C., Jayaraman, A., & Hahn, J.
(2010).
Using the Tet-On system to develop a procedure for extracting transcription factor activation dynamics. Molecular Biosystems.
6(10), 1883-1889.
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Englert, D. L., Adase, C. A., Jayaraman, A., & Manson, M. D.
(2010).
Repellent Taxis in Response to Nickel Ion Requires Neither Ni2+ Transport nor the Periplasmic NikA Binding Protein (vol 192, pg 2633, 2010). Journal of Bacteriology.
192(16), 4259-4259.
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Englert, D. L., Adase, C. A., Jayaraman, A., & Manson, M. D.
(2010).
Repellent taxis in response to nickel ion requires neither Ni2+ transport nor the periplasmic NikA binding protein. Journal of Bacteriology.
192(10), 2633-2637.
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Bansal, T., Alaniz, R. C., Wood, T. K., & Jayaraman, A.
(2010).
The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation. Proceedings of the National Academy of Sciences of the United States of America.
107(1), 228-233.
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Englert, D. L., Manson, M. D., & Jayaraman, A.
(2010).
A microfluidic device for quantifying bacterial chemotaxis in stable concentration gradients. Journal of Visualized Experiments.
1779.
-
Kim, J., Hegde, M., & Jayaraman, A.
(2010).
Microfluidic co-culture of epithelial cells and bacteria for investigating soluble signal-mediated interactions. Journal of Visualized Experiments.
1749.
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Kim, J., Hegde, M., & Jayaraman, A.
(2010).
Co-culture of epithelial cells and bacteria for investigating host-pathogen interactions. Lab on a Chip.
10(1), 43-50.
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Kim, J., Hegde, M., & Jayaraman, A.
(2010).
Microfluidic Co-culture of Epithelial Cells and Bacteria for Investigating Soluble Signal-mediated Interactions. Journal of Visualized Experiments.
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Huang, J., Kim, J., Agrawal, N., Sudarson, A. P., Maxim, J. E., Jayaraman, A., & Ugaz, V. M.
(2009).
Rapid Fabrication of Bio-inspired 3D Microfluidic Vascular Networks. ADVANCED MATERIALS.
21(35), 3567-+.
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Wang, S., Chen, P. C., Berthiaume, F., Toner, M., Jayaraman, A., & Yarmush, M. L.
(2009).
Dynamic effect of heat shock pretreatment on apoptotic responses to TNF-alpha in liver cells. Journal of Biomechanical Engineering.
131(7), 071003.
-
Englert, D. L., Manson, M. D., & Jayaraman, A.
(2009).
Flow-based microfluidic device for quantifying bacterial chemotaxis in stable, competing gradients. Applied and Environmental Microbiology.
75(13), 4557-4564.
-
Newton, B. W., Russell, W. K., Russell, D. H., Ramaiah, S. K., & Jayaraman, A.
(2009).
Liver proteome analysis in a rodent model of alcoholic steatosis. Journal of Proteome Research.
8(4), 1663-1671.
-
Huang, J., Kim, J., Agrawal, N., Sudarsan, A. P., Maxim, J. E., Jayaraman, A., & Ugaz, V. M.
(2009).
Artificial Vasculature: Rapid Fabrication of Bioinspired 3D Microfluidic Vascular Networks (Adv. Mater. 35/2009). ADVANCED MATERIALS.
21(35), na-na.
-
Xie, S., Moya, C., Bilgin, B., Jayaraman, A., & Walton, S. P.
(2009).
Emerging affinity-based techniques in proteomics. Expert Review of Proteomics.
6(5), 573-583.
-
Lai, N., Jayaraman, A., & Lee, K.
(2009).
Enhanced proliferation of human umbilical vein endothelial cells and differentiation of 3T3-L1 adipocytes in coculture. Tissue Engineering Part A.
15(5), 1053-1061.
-
Jayaraman, A., Maguire, T., Vemula, M., Kwon, D. W., Vannucci, M., Berthiaume, F., & Yarmush, M. L.
(2009).
Gene expression profiling of long-term changes in rat liver following burn injury. Journal of Surgical Research.
152(1), 3-17.e2.
-
Janakiraman, V., Englert, D., Jayaraman, A., & Baskaran, H.
(2009).
Modeling growth and quorum sensing in biofilms grown in microfluidic chambers. Annals of Biomedical Engineering.
37(6), 1206-1216.
-
Englert, D. L., Jayaraman, A., & Manson, M. D.
(2009).
Microfluidic techniques for the analysis of bacterial chemotaxis. Methods in molecular biology (Clifton, N.J.).
571, 1-23.
-
Banerjee, A., Russell, W. K., Jayaraman, A., & Ramaiah, S. K.
(2008).
Identification of proteins to predict the molecular basis for the observed gender susceptibility in a rat model of alcoholic steatohepatitis by 2-D gel proteomics. Proteomics.
8(20), 4327-4337.
-
Soni, K. A., Jesudhasan, P. R., Cepeda, M., Williams, B., Hume, M., Russell, W. K., Jayaraman, A., & Pillai, S. D.
(2008).
Autoinducer AI-2 is involved in regulating a variety of cellular processes in Salmonella Typhimurium. Foodborne Pathogens and Disease.
5(2), 147-153.
-
Huang, Z., Senocak, F., Jayaraman, A., & Hahn, J.
(2008).
Integrated modeling and experimental approach for determining transcription factor profiles from fluorescent reporter data. BMC Systems Biology.
2(1), 64.
-
King, K. R., Wang, S., Jayaraman, A., Yarmush, M. L., & Toner, M.
(2008).
Microfluidic flow-encoded switching for parallel control of dynamic cellular microenvironments. Lab on a Chip.
8(1), 107-116.
-
Senocak, F. S., Si, Y., Moya, C., Russell, W. K., Russell, D. H., Lee, K., & Jayaraman, A.
(2007).
Effect of uncoupling protein-1 expression on 3T3-L1 adipocyte gene expression. FEBS Letters.
581(30), 5865-5871.
-
Soni, K., Jesudhasan, P., Cepeda, M., Williams, B., Hume, M., Russell, W. K., Jayaraman, A., & Pillai, S. D.
(2007).
Proteomic analysis to identify the role of LuxS/AI-2 mediated protein expression in Escherichia coli O157:H7. Foodborne Pathogens and Disease.
4(4), 463-471.
-
Chu, Y., Jayaraman, A., & Hahn, J.
(2007).
Parameter sensitivity analysis of IL-6 signalling pathways. 1(6), 342-352.
-
Bansal, T., Englert, D., Lee, J., Hegde, M., Wood, T. K., & Jayaraman, A.
(2007).
Differential effects of epinephrine, norepinephrine, and indole on Escherichia coli O157:H7 chemotaxis, colonization, and gene expression. Infection and Immunity.
75(9), 4597-4607.
-
Lee, J., Bansal, T., Jayaraman, A., Bentley, W. E., & Wood, T. K.
(2007).
Enterohemorrhagic Escherichia coli biofilms are inhibited by 7-hydroxyindole and stimulated by isatin. Applied and Environmental Microbiology.
73(13), 4100-4109.
-
Singh, A., Jayaraman, A., & Hahn, J.
(2007).
A case study representing signal transduction in liver cells as a feedback control problem. Chemical Engineering Education.
41(3), 177-182.
-
Banta, S., Vemula, M., Yokoyama, T., Jayaraman, A., Berthiaume, F., & Yarmush, M. L.
(2007).
Contribution of gene expression to metabolic fluxes in hypermetabolic livers induced through burn injury and cecal ligation and puncture in rats. Biotechnology and Bioengineering.
97(1), 118-137.
-
Si, Y., Palani, S., Jayaraman, A., & Lee, K.
(2007).
Effects of forced uncoupling protein 1 expression in 3T3-L1 cells on mitochondrial function and lipid metabolism. Journal of Lipid Research.
48(4), 826-836.
-
Lee, J., Jayaraman, A., & Wood, T. K.
(2007).
Indole is an inter-species biofilm signal mediated by SdiA. BMC Microbiology.
7(1), 42.
-
King, K. R., Wang, S., Irimia, D., Jayaraman, A., Toner, M., & Yarmush, M. L.
(2007).
A high-throughput microfluidic real-time gene expression living cell array. Lab on a Chip.
7(1), 77-85.
-
Singh, A., Jayaraman, A., & Hahn, J.
(2006).
Modeling regulatory mechanisms in IL-6 signal transduction in hepatocytes. Biotechnology and Bioengineering.
95(5), 850-862.
-
Banta, S., Vemula, M., Yokoyama, T., Jayaraman, A., Berthiaume, F., & Yarmush, M. L.
(2006).
Contribution of Gene Expression to Metabolic Fluxes in Hypermetabolic Livers Induced Through Burn Injury and Polymicrobial Sepsis in Rats. 27(2), s163-S163.
-
Duan, X., Yarmush, D., Berthiaume, F., Jayaraman, A., & Yarmush, M. L.
(2005).
Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins. Proteomics.
5(15), 3991-4000.
-
Jayaraman, A., Roberts, K. A., Yoon, J., Yarmush, D. M., Duan, X., Lee, K., & Yarmush, M. L.
(2005).
Identification of neutrophil gelatinase-associated lipocalin (NGAL) as a discriminatory marker of the hepatocyte-secreted protein response to IL-1beta: a proteomic analysis. Biotechnology and Bioengineering.
91(4), 502-515.
-
Jayaraman, A., Yarmush, M. L., & Roth, C. M.
(2005).
Evaluation of an in vitro model of hepatic inflammatory response by gene expression profiling. Tissue Engineering.
11(1-2), 50-63.
-
Duan, X., Yarmush, D. M., Berthiaume, F., Jayaraman, A., & Yarmush, M. L.
(2004).
A mouse serum two-dimensional gel map: application to profiling burn injury and infection. Electrophoresis.
25(17), 3055-3065.
-
Thompson, D. M., King, K. R., Wieder, K. J., Toner, M., Yarmush, M. L., & Jayaraman, A.
(2004).
Dynamic gene expression profiling using a microfabricated living cell array. Analytical Chemistry.
76(14), 4098-4103.
-
Duan, X., Yarmush, D. M., Jayaraman, A., & Yarmush, M. L.
(2004).
Dispensable role for interferon-gamma in the burn-induced acute phase response: a proteomic analysis. Proteomics.
4(6), 1830-1839.
-
Vemula, M., Berthiaume, F., Jayaraman, A., & Yarmush, M. L.
(2004).
Expression profiling analysis of the metabolic and inflammatory changes following burn injury in rats. Physiological Genomics.
18(1), 87-98.
-
Jayaraman, A., Yarmush, M. L., & Roth, C. M.
(2002).
Molecular Bioengineering. Industrial & Engineering Chemistry Research.
41(3), 441-455.
-
Ismail, K. M., Gehrig, T., Jayaraman, A., Wood, T. K., Trandem, K., Arps, P. J., & Earthman, J. C.
(2002).
Corrosion Control of Mild Steel by Aerobic Bacteria under Continuous Flow Conditions. Corrosion: journal of science and engineering.
58(5), 417-423.
-
Ornek, D., Jayaraman, A., Syrett, B. C., Hsu, C., Mansfeld, F. B., & Wood, T. K.
(2002).
Pitting corrosion inhibition of aluminum 2024 by Bacillus biofilms secreting polyaspartate or gamma-polyglutamate. Applied Microbiology and Biotechnology.
58(5), 651-657.
-
Jayaraman, A., Yarmush, D. M., Yarmush, M. L., & Roth, C. M.
(2001).
Dynamic Expression Profile of the Acute Phase Response. 22, s78-S78.
-
rnek, D., Jayaraman, A., Wood, T. K., Sun, Z., Hsu, C. H., & Mansfeld, F.
(2001).
Pitting corrosion control using regenerative biofilms on aluminium 2024 in artificial seawater. Corrosion Science.
43(11), 2121-2133.
-
Jayaraman, A., Walton, S. P., Yarmush, M. L., & Roth, C. M.
(2001).
Rational selection and quantitative evaluation of antisense oligonucleotides. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.
1520(2), 105-114.
-
Jayaraman, A.
(2000).
A brief overview of gem materials: Natural and synthetic. CURRENT SCIENCE.
79(11), 1555-1565.
-
Jayaraman, A., Yarmush, M. L., & Roth, C. M.
(2000).
Dynamics of gene expression in rat hepatocytes under stress. Metabolic Engineering.
2(3), 239-251.
-
Jayaraman, A., Ornek, D., Duarte, D. A., Lee, C. C., Mansfeld, F. B., & Wood, T. K.
(1999).
Axenic aerobic biofilms inhibit corrosion of copper and aluminum. Applied Microbiology and Biotechnology.
52(6), 787-790.
-
Jayaraman, A., Mansfeld, F. B., & Wood, T. K.
(1999).
Inhibiting sulfate-reducing bacteria in biofilms by expressing the antimicrobial peptides indolicidin and bactenecin. Journal of Industrial Microbiology and Biotechnology.
22(3), 167-175.
-
Jayaraman, A., Hallock, P. J., Carson, R. M., Lee, C. C., Mansfeld, F. B., & Wood, T. K.
(1999).
Inhibiting sulfate-reducing bacteria in biofilms on steel with antimicrobial peptides generated in situ. Applied Microbiology and Biotechnology.
52(2), 267-275.
-
Ismail, K. M., Jayaraman, A., Wood, T. K., & Earthman, J. C.
(1999).
The influence of bacteria on the passive film stability of 304 stainless steel. Electrochimica Acta.
44(26), 4685-4692.
-
Jayaraman, A., Sun, A. K., & Wood, T. K.
(1998).
Characterization of axenic Pseudomonas fragi and Escherichia coli biofilms that inhibit corrosion of SAE 1018 steel. Journal of Applied Microbiology.
84(4), 485-492.
-
Jayaraman, A., Cheng, E. T., Earthman, J. C., & Wood, T. K.
(1997).
Importance of biofilm formation for corrosion inhibition of SAE 1018 steel by axenic aerobic biofilms. Journal of Industrial Microbiology and Biotechnology.
18(6), 396-401.
-
Jayaraman, A., Cheng, E. T., Earthman, J. C., & Wood, T. K.
(1997).
Axenic aerobic biofilms inhibit corrosion of SAE 1018 steel through oxygen depletion. Applied Microbiology and Biotechnology.
48(1), 11-17.
-
Jayaraman, A., Earthman, J. C., & Wood, T. K.
(1997).
Corrosion inhibition by aerobic biofilms on SAE 1018 steel. Applied Microbiology and Biotechnology.
47(1), 62-68.
-
Jayaraman, A., De Bernardez Clark, E., & Goldberg, E.
(1997).
Thermal unfolding of bacteriophage T4 short tail fibers. Biotechnology Progress.
13(6), 837-843.
-
Baranwal, G., Pilla, R., Goodlett, B., Jayaraman, A., Rutkowski, J. M., Alaniz, R., & Mitchell, B. M.
Metabolomic Study To Identify Common Metabolites In Two Different Mouse Models Of Hypertension. HYPERTENSION.
78(Suppl_1), amp42-amp42.
-
Ding, Y., Yanagi, K., Yang, F., Callaway, E., Cheng, C., Hensel, M. E., ... Jayaraman, A.
Oral supplementation of gut microbial metabolite indole-3-acetate alleviates diet-induced steatosis and inflammation in mice. eLife.
12.
-
Penarete-Acosta, D., Stading, R., Emerson, L., Horn, M., Chakraborty, S., Han, A., & Jayaraman, A.
(2024).
A microfluidic co-culture model for investigating colonocytes-microbiota interactions in colorectal cancer. 24(15), 3690-3703.
-
book
-
Jayaraman, A., & Wood, T. K.
(2008).
Bacterial quorum sensing: signals, circuits, and implications for biofilms and disease. Ed. 10.
Annual Reviews.
-
Yarmush, M. L., & Jayaraman, A.
(2002).
Advances in proteomic technologies. Ed. 4.
Annual Reviews.
-
Jayaraman, A., & Wood, T. K.
(2008).
Bacterial quorum sensing: signals, circuits, and implications for biofilms and disease. Ed. 10.
Annual Reviews.
-
chapter
-
Kotu, S. P., Han, S., Han, A., Mannan, S., & Jayaraman, A.
(2019).
Lab-on-a-Chip Model for Investigating the Effect of Biocides on Co-Culture Biofilms. Oilfield Microbiology.
(pp. 129-142).
Taylor & Francis.
-
Sule, N., Penarete-Acosta, D., Englert, D. L., & Jayaraman, A.
(2018).
A Static Microfluidic Device for Investigating the Chemotaxis Response to Stable, Non-linear Gradients. Methods in molecular biology (Clifton, N.J.).
BACTERIAL CHEMOSENSING.
(pp. 47-59).
Springer Nature.
-
Huang, J., Jayaraman, A., & Ugaz, V. M.
(2013).
Microvascular Networks for Tissue Engineering. Microfluidic Cell Culture Systems.
(pp. 27-52).
Elsevier.
-
Huang, J., Jayaraman, A., & Ugaz, V. M.
(2013).
Chapter 2 Microvascular Networks for Tissue Engineering. Microfluidic Cell Culture Systems.
(pp. 27-52).
Elsevier.
-
King, K. R., Yarmush, M. L., & Jayaraman, A.
(2009).
Expression Profiling Using Microfluidic Living Cell Arrays. MICROARRAYS: PREPARATION, MICROFLUIDICS, DETECTION METHODS, AND BIOLOGICAL APPLICATIONS.
(pp. 211-226).
Springer Nature.
-
Kotu, S. P., Han, S., Han, A., Mannan, S., & Jayaraman, A.
(2019).
Lab-on-a-Chip Model for Investigating the Effect of Biocides on Co-Culture Biofilms. Oilfield Microbiology.
(pp. 129-142).
Taylor & Francis.
-
conference paper
-
Lee, D., Jayaraman, A., & Kwon, J.
(2021).
A Hybrid Mechanistic Data-driven Approach for Modeling Uncertain Intracellular Signaling Pathways. Proceedings of the ... American Control Conference. American Control Conference.
1903-1908.
-
Lee, D., Ding, Y., Jayaraman, A., & Kwon, J.
(2020).
Derivation of a Dynamic Model for Palmitate-induced NF kappa B Signaling Pathway through Systems Biology Approach. Proceedings of the ... American Control Conference. American Control Conference.
5028-5033.
-
Letsinger, A. C., Menon, R., Granados, J. Z., Breidenbach, B. M., Nagel, E. C., Castro, T. N., ... Lightfoot, J. T.
(2019).
The Gut Microbiome Modulates Diet's Effect on the Regulation of Physical Activity. Medicine & Science in Sports & Exercise.
1001-1001.
-
Lee, D., Jayaraman, A., & Kwon, J. S.
(2019).
Identification of Heterogeneous Parameters in an Intracellular Reaction Network from Population Snapshot Measurements through Sensitivity Analysis and Neural Network. IFAC-PapersOnLine.
107-112.
-
Lopez-Gelston, C., Eshghjoo, S., Weeks, C., DeLeonibus, S., Jayaraman, A., Alaniz, R. C., & Chakraborty, S.
(2018).
Gut Microbiota Derived Metabolites Impact Lymphatic Inflammatory Mechanisms. Circulation.
-
Albright, V., Hlushko, H., Nelson, H., Co, C., Armbrister, S., Hernandez, S., ... Sukhishvili, S.
(2018).
Trapping of antibacterial agents within hydrophobic films of polyphosphazene polyelectrolytes. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
Lee, D., Ding, Y., Jayaraman, A., & Sang-Il Kwon, J.
(2018).
Integrative Approach to Extract the Single-cell Dynamics of LPS-induced NF kappa B Signal Pathway through Flow Cytometry Measurements and Parameter Estimation. Proceedings of the ... American Control Conference. American Control Conference.
1975-1980.
-
Eshghjoo, S., Ding, Y., Hunt, C., Jayaraman, A., & Alaniz, R. C.
(2018).
Microbiota Regulation of Pro-atherogenic Phagocytes - Separating Metabolic and Inflammatory Mechanisms. Journal of Immunology.
-
Ding, Y., Krishnan, S., Alaniz, R. C., Lee, K., & Jayaraman, A.
(2018).
Microbiota metabolites derived from tryptophan modulate macrophage inflammation and migration through AMP-activated protein kinase. Journal of Immunology.
-
Choi, B. H., Huang, J. H., Priye, A., Presley, B., Jayaraman, A., & Ugaz, V. M.
(2016).
A membraneless high-throughput micro-separator. 1525-1526.
-
Kotu, S. P., Erbay, C., Sobahi, N., Han, A., Mannan, S., & Jayaraman, A.
(2016).
Integration of electrochemical impedance spectroscopy and microfluidics for investigating microbially influenced corrosion using co-culture biofilms. NACE - International Corrosion Conference Series.
4312-4325.
-
Contreras-Naranjo, J. C., Chang, J., Jayaraman, A., & Ugaz, V. M.
(2016).
Interference-based probe of the nano-scale topography of microparticles. 1352-1353.
-
Lee, K., Krishnan, S., Choi, M., Ding, Y., Saedi, N., Jayaraman, A., & Yarmush, M. L.
(2016).
Using metabolomics to identify gut microbiota-derived metabolites as host inflammation modulators. 177-178.
-
Howsmon, D., Hahn, J., Steinmeyer, S., Jayaraman, A., & Alaniz, R.
(2015).
Neural Networks Elucidate T Cell Priming Conditions for Adoptive Transfer. 2015 41ST ANNUAL NORTHEAST BIOMEDICAL ENGINEERING CONFERENCE (NEBEC).
1-2.
-
Krishnan, S., Choi, M., Ding, Y., Saedi, N., Yarmush, M. L., Jayaraman, A., & Lee, K.
(2015).
Identification of gut microbiota-derived metabolites as liver inflammation modulators in non-alcoholic fatty liver disease. 703-705.
-
Sims, J. K., Choi, K., Manteiga, S., Russell, W., Jayaraman, A., & Lee, K.
(2013).
Metabolomic and proteomic analysis of metabolic enzyme disruption in adipocytes. 173-174.
-
Wang, H., Longsine-Parker, W., Koo, C., Kim, J., Kim, B. J., Jayaraman, A., & Han, A.
(2013).
Microfluidic electro-sonoporation by simultaneous application of electric field and acoustic field. 1332-1334.
-
Chaar, D., Hahn, J., Jayaraman, A., Alaniz, R., & Steinmeyer, S.
(2013).
Regulatory t-cell differentiation plasticity model. 701-702.
-
Bansal, L., Maiti, S., Jayaraman, A., Laird, C., & Hahn, J.
(2012).
Modeling of fluorescent protein-labeled cell populations to analyze transcriptional and division effects on fluorescent intensity distributions
-
Huang, J. H., Priye, A., Jayaraman, A., & Ugaz, V. M.
(2012).
Harnessing enzymatically machined nanoand micro-scale surface topographies for high-throughput separations. 139-141.
-
Huang, J. H., Kim, J., Jayaraman, A., & Ugaz, V. M.
(2011).
A new approach to embed branched 3D microchannel networks in hydrogel substrates: Fabrication and transport analysis. 91-93.
-
Hegde, M., Kim, J., Hong, S. H., Wood, T. K., & Jayaraman, A.
(2011).
Designer biofilms: Controlling biofilm formation and dispersal using a synthetic quorum sensing circuit in microfluidic devices. 1554-1556.
-
Bansal, L., Yang, E., Nelson, R., Jayaraman, A., & Hahn, J.
(2011).
Experimental design of systems involving multiple fluorescent reporters
-
Wang, H., Kim, J., Jayaraman, A., & Han, A.
(2011).
On-demand geometric metering-based multi-reagent mixture generator for robust high-throughput single cell environmental toxin screening. 831-833.
-
Wang, H., Kim, J., Jayaraman, A., Cypert, M., Hua, J., Bittner, M., & Han, A.
(2011).
A HIGH-THROUGHPUT FULLY-AUTOMATED MICROFLUIDIC LIVE CELL ARRAY FOR COMBINATION DRUG TREATMENT ANALYSIS OF COLORECTAL CANCER CELLS. 2148-2151.
-
Hegde, M., Englert, D. L., Wood, T., Manson, M., & Jayaraman, A.
(2010).
Listening to new signals with old ears: Sensing and recognition of the quorum sensing signal AI-2 by the TSR chemoreceptor
-
Kim, J. Y., Taylor, D., Rege, K., Kim, H. S., Han, A. R., & Jayaraman, A.
(2010).
Novel high-throughput screening system for cancer therapy with simultaneous combination treatments. 836-838.
-
Huang, J. H., Kim, J., Jayaraman, A., & Ugaz, V. M.
(2010).
Sculpting tissue scaffolds with embedded 3-D vasculature. 2026-2028.
-
Huang, Z., Moya, C., Cheng, P., Jayaraman, A., & Hahn, J.
(2009).
Mathematical modeling for IL6 and IL10 signal transduction in steatosis
-
Kim, J., Hegde, M., & Jayaraman, A.
(2009).
A microfluidic device for investigating concentration-dependent interaction between signals on bacterial biofilm formation. 1500-1502.
-
Kim, J., Taylor, D., Hegde, M., Rege, K., & Jayaraman, A.
(2009).
Combination drug treatment screening using a microfluidc cell array. 1494-1496.
-
Huang, Z., Senocak, F., Jayaraman, A., & Hahn, J.
(2009).
Solution of Inverse Problems for Obtaining Protein Concentrations from Fluorescent Microscopy Images. Proceedings of the ... American Control Conference. American Control Conference.
1688-1693.
-
Bansal, T., Wood, T. K., & Jayaraman, A.
(2008).
Inter-kingdom signaling. A signal-mediated framework of host-pathogen interactions
-
Kim, J., Senocak, F., Hegde, M., & Jayaraman, A.
(2008).
Micropatterned co-culture model of bacteria and epithelial cells for investigating signal-mediated host-pathogen interactions
-
Huang, Z., Senocak, F., Jayaraman, A., & Hahn, J.
(2008).
Quantitative measurement technique for transcription factor profiles
-
Huang, J. H., Kim, J., Jayaraman, A., & Ugaz, V. M.
(2008).
Rapid fabrication and characterization of 3-D branched microvascular flow networks
-
Kim, J. Y., Senocak, F., Hegde, M., & Jayaraman, A.
(2008).
Micropatterned co-culture model of bacteria and epithelial cells for investigating signal-mediated host-pathogen interactions. 1208-1210.
-
Huang, J. H., Kim, J., Jayaraman, A., & Ugaz, V. M.
(2008).
Rapid fabrication of 3-D branched microvascular flow networks. 1435-1437.
-
Chu, Y., Singh, A. K., Jayaraman, A., & Hahn, J.
(2006).
Sensitivity analysis-based approach for identifying key steps in cell signaling for hepatocytes stimulated by II-6
-
Singh, A., Jayaraman, A., & Hahn, J.
(2006).
Effect of SHP-2, SOCS3, and PP2 on IL-6 signal transduction in hepatocytes. Proceedings of the ... American Control Conference. American Control Conference.
3771-+.
-
Jayaraman, A., Palani, S., Si, Y., & Lee, K.
(2005).
Adipocyte metabolic engineering for increased fatty acid oxidation through uncoupling protein over-expression. 8465.
-
Singh, A. K., Jayaraman, A., & Hahn, J.
(2005).
Mathematical model of IL-6 signal transduction in hepatocytes. 8481-8485.
-
Wang, S., King, K. R., Chen, P. C., Berthiaume, F., Toner, M., Jayaraman, A., & Yarmush, M. L.
(2005).
Microdevice for high throughput analysis of cross-talk between signaling pathways: Application to heat shock and apoptosis responses in liver cells. 8899.
-
Wang, S., King, K. R., Wieder, K. J., Toner, M., Jayaraman, A., & Yarmush, M. L.
(2005).
Study of heat shock effects on inflammatory signaling using a microfluidic Living Cell Array. 9195.
-
King, K. R., Wang, S., Jayaraman, A., Yarmush, M., & Toner, M.
(2005).
Screening Cellular Responses to Cytokine Pulses in a Microfluidic Device. 361-362.
-
King, K. R., Wang, S., Irimia, D., Yarmush, M., Jayaraman, A., & Toner, M.
(2005).
Dynamic profiling of hepatocyte stress responses in a microfluidic multi-clone living cell array. 533-535.
-
Walton, S. P., Jayaraman, A., Stephanopoulos, G. N., Yarmush, M. L., & Roth, C. M.
(1999).
Prediction of antisense oligonucleotide binding affinity and activity in cell culture. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
96.
-
de Figueiredo, P., Guo, F., Das, J., Ding, Y., Jayaraman, A., Alaniz, R. C., & Song, J.
A metabolically engineered bacterial vaccine protects against arthritis in mice. Journal of Immunology.
66.13-66.13.
-
Lee, D., Jayaraman, A., & Kwon, J.
(2021).
A Hybrid Mechanistic Data-driven Approach for Modeling Uncertain Intracellular Signaling Pathways. Proceedings of the ... American Control Conference. American Control Conference.
1903-1908.
-
institutional repository document
-
Penarete-Acosta, D., Stading, R., Emerson, L., Horn, M., Chakraborty, S., Han, A., & Jayaraman, A.
(2023).
A microfluidic model of colonocyte-microbiota interaction mimicking the colorectal cancer microenvironment
-
Das, J. K., Guo, F., Hunt, C., Steinmeyer, S., Plocica, J. A., Kobayashi, K. S., ... Song, J.
A metabolically engineered bacterium controls autoimmunity by remodeling the pro-inflammatory microenvironment
-
Penarete-Acosta, D., Mittal, M., Chakraborty, S., Han, A., & Jayaraman, A.
Dietary Fiber Modulates Macrophage Activity in a Microfluidic Model of Colonocyte-Microbiota Interactions in Colorectal Cancer
-
Penarete-Acosta, D., Stading, R., Emerson, L., Horn, M., Chakraborty, S., Han, A., & Jayaraman, A.
(2023).
A microfluidic model of colonocyte-microbiota interaction mimicking the colorectal cancer microenvironment
Research
principal investigator on
- Modeling and Analysis of the Role of Microbiota Metabolites in T-Cell Differentiation- awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2015 - 2021
- Development of a continuous genome shuffling approach to expedite adaptive laboratory evolution awarded by National Science Foundation - (Arlington, Virginia, United States) 2016 - 2020
- Collaborative Research: Identification of Immunomodulatory Microbiota Metabolites awarded by National Science Foundation - (Arlington, Virginia, United States) 2013 - 2017
co-principal investigator on
- Dietary Flavonoids-Microbiota-Ah Receptor Interactions in the Gut awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2018 - 2022
- An Ultra-high Throughput Microfluidic System for 3-D Assembly of Microbial Communities awarded by United States Army - (Washington D.C., District of Columbia, United States) 2019 - 2021
- Study the Interaction Between Lipopolysaccharide-Binding Protein and Immune Cell Membranes awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2019 - 2021
- Diet induced modifications of microbiota metabolites in colon tumorigenesis awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2016 - 2021
- Role of Aryl Hydrocarbon Receptor in Microbiota-Colon Stem Cell Interactions awarded by National Institute of Environmental Health Sciences - (Durham, North Carolina, United States) 2016 - 2021
- AI-2 Chemotaxis and Biofilm Formation awarded by National Science Foundation - (Arlington, Virginia, United States) 2011 - 2017
- Rapid Fabrication of Bio-Inspired Microvascular Networks awarded by National Science Foundation - (Arlington, Virginia, United States) 2011 - 2016
investigator on
- Texas A&M Center for Environmental Health Research awarded by National Institute of Environmental Health Sciences - (Durham, North Carolina, United States) 2019 - 2024
- Nutrition, Biostatistics and Bioinformatics Training Grant awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2013 - 2021
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- BICH491 Research Instructor
- BIOT684 Directed Prof Internship Instructor
- BIOT684 Directed Prof Intrn: In-ab Instructor
- BIOT685 Directed Studies Instructor
- BMEN691 Research Instructor
- CHEN204 Elementary Chem Engr Instructor
- CHEN382 Bioprocess Engineering Instructor
- CHEN471 Bioreactor Engineering: China Instructor
- CHEN491 Hnr-research Instructor
- CHEN681 Seminar Instructor
- CHEN684 Professional Internship: In-ab Instructor
- CHEN685 Directed Studies Instructor
- CHEN691 Research Instructor
- CHEN695 Grad Mentoring Seminar I Instructor
- CHEN696 Grad Mentoring Seminar Ii Instructor
Works By Students
chaired theses and dissertations
-
Bansal, Tarun (2011-10). Inter-Kingdom Signaling Interactions in Enterohemorrhagic Escherichia coli Infections.
-
Choi, Kyungoh (2013-07). Systems Biology of Microbiota Metabolites and Adipocyte Transcription Factor Network.
-
Englert, Derek Lynn (2011-02). Microfluidic Systems for Investigating Bacterial Chemotaxis and Colonization.
-
Hegde, Manjunath (2012-02). Inter- and Intra-kingdom Signaling in Bacterial Chemotaxis, Biofilm Formation, and Virulence.
-
Hsieh, Min-Chi (2018-08). Viral Protein Encapsulation for Vaccine Vehicles: Characterization and In Vitro Studies.
-
Jani, Sneha Jagdish (2017-05). Chemotaxis toward Autoinducer-2 and Its Role in Biofilm Development in Escherichia coli.
-
Kang, Jia (2015-08). An Efficient Interior-Point Decomposition Algorithm for Parallel Solution of Large-Scale Nonlinear Problems with Significant Variable Coupling.
-
Kim, Dae Nyun (2012-10). Inter-kingdom Recognition of Norepinephrine by E. Coli : Identification of the Receptors Involved in Chemotaxis.
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Kim, Sun Ho (2009-05). Role of AI-2 in oral biofilm formation using microfluidic devices.
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Klemashevich, Cory Lee (2016-12). The Microbially Derived Metabolite Indole Attenuates Obesity Associated Inflammatory Processes in Adipocytes and Macrophages.
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Kohli, Nandita (2017-05). Investigating Indole-Mediated Modulation of Salmonella Virulence and Chemotaxis.
-
Laible, Allyson Marie (2009-05). Modeling green fluorescent protein transcription, translation and modification as a method to obtain NF-kappaB activation profiles.
-
Newton, Billy Walker (2012-07). Proteomics of Oxidative Stress Using Inducible CYP2E1 Expressing HepG2 Cells and 3T3-L1 Adipocytes as Model Systems.
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Olson, Michelle Lynn (2018-08). Understanding Biofilm Formation in Co-Cultures of Candida Albicans and Candida Glabrata.
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Palani, Santhosh (2006-10). Increased fat oxidation in 3T3-L1 adipocytes through forced expression of UCP 1.
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Pasupuleti, Sasi Kiran (2017-12). Chemotaxis of Escherichia Coli Towards Norepinephrine Metabolites.
-
Steinmeyer, Shelby H (2018-04). Metabolite Signals from the Microbiota: Instructing T Cell Fate and Function.
Background
education and training
awards and honors
- Fellow, conferred by American Institute for Medical and Biological Engineering - (Washington D.C., District of Columbia, United States), 2015
- Engineering Genesis Award, conferred by Texas A&M University - (College Station, Texas, United States), 2015
- Faculty Early Career Development (CAREER) Program, conferred by National Science Foundation - (Arlington, Virginia, United States), 2009
- Ray Nesbitt Development Professorship, conferred by Texas A&M University - (College Station, Texas, United States), 2009
Contact
first name
- Arul
has last name
- Jayaraman
mailing address
-
Texas A&M University
Chemical Engineering
3122 TAMU
College Station, TX 77843-3122
USA
Other
In the News
- arulj@tamu.edu