A microfluidic device for investigating concentration-dependent interaction between signals on bacterial biofilm formation Conference Paper uri icon

abstract

  • In this paper, we report the development of a microfluidic model for investigating bacterial biofilm formation and organization in response to different quorum sensing molecules such as autoinducer-2 and indole. A key feature of the proposed model is that the gradient concentration of QS molecules are generated in each chamber without any mixing. This model can be used for developing a fundamental understanding of events leading to bacterial attachment to surfaces that are important in infections. 2009 CBMS.

published proceedings

  • Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

author list (cited authors)

  • Kim, J., Hegde, M., & Jayaraman, A.

complete list of authors

  • Kim, J||Hegde, M||Jayaraman, A

publication date

  • January 2009