HR job title
- Retired Research Professor
- Contact Info
- 1 979 458 1149
Mouneimne, Roula Research Professor
Positions
- Research Professor, Veterinary Integrative Biosciences, School of Veterinary Medicine and Biomedical Sciences
For the past 24 years my research focused on: 1- The development of methods in the fluorescence microscopy field that achieve data acquisition and analysis in real time, quantitative analysis, and mathematical modeling of cellular signaling. 2- The development of novel technological tools to decipher molecular and physiological events in cells and immunological tissues under normal toxin exposure and disease conditions.
- Overview
- Publications
- Research
- Works By Students
- Background
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Overview
Publications
selected publications
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academic article
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Elswood, J., Pearson, S. J., Payne, H. R., Barhoumi, R., Rijnkels, M., & W Porter, W.
(2021).
Autophagy regulates functional differentiation of mammary epithelial cells. Autophagy.
17(2), 420-438.
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Legere, R. M., Cohen, N. D., Poveda, C., Bray, J. M., Barhoumi, R., Szule, J. A., ... Pollet, J.
(2021).
Safe and effective aerosolization of in vitro transcribed mRNA to the respiratory tract epithelium of horses without a transfection agent. Scientific Reports.
11(1), 371.
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Ding, S., Yang, J., Feng, X., Pandey, A., Barhoumi, R., Zhang, D., ... de Figueiredo, P.
(2021).
Interactions between fungal hyaluronic acid and host CD44 promote internalization by recruiting host autophagy proteins to forming phagosomes. iScience.
24(3), 102192-102192.
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Allegro, A. R., Barhoumi, R., Bordin, A. I., Bray, J. M., & Cohen, N. D.
(2021).
Uptake and replication in Acanthamoeba castellanii of a virulent (pVAPA-positive) strain of Rhodococcus equi and its isogenic, plasmid-cured strain. Veterinary Microbiology.
257, 109069-109069.
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Yu, X., Guo, F., Mouneimne, R. B., & Zhu, G.
(2020).
Cryptosporidium parvum Elongation Factor 1 Participates in the Formation of Base Structure at the Infection Site During Invasion. Journal of Infectious Diseases.
221(11), 1816-1825.
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Chaki, S. P., Barhoumi, R., & Rivera, G. M.
(2019).
Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion. Cancer Medicine.
8(17), 7385-7398.
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Pearson, S. J., Roy Sarkar, T., McQueen, C. M., Elswood, J., Schmitt, E. E., Wall, S. W., ... Porter, W. W.
(2019).
ATM-dependent activation of SIM2s regulates homologous recombination and epithelial-mesenchymal transition. Oncogene.
38(14), 2611-2626.
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Pearson, S. J., Elswood, J., Barhoumi, R., Ming-Whitfield, B., Rijnkels, M., & Porter, W. W.
(2019).
Loss of SIM2s inhibits RAD51 binding and leads to unresolved replication stress. Breast Cancer Research.
21(1), 125.
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Chamoun-Emanuelli, A. M., Bryan, L. K., Cohen, N. D., Tetrault, T. L., Szule, J. A., Barhoumi, R., & Whitfield-Cargile, C. M.
(2019).
NSAIDs disrupt intestinal homeostasis by suppressing macroautophagy in intestinal epithelial cells. Scientific Reports.
9(1), 14534.
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Pea, B., Saha, S., Barhoumi, R., Burghardt, R. C., & Dunbar, K. R.
(2018).
Ruthenium(II)-Polypyridyl Compounds with -Extended Nitrogen Donor Ligands Induce Apoptosis in Human Lung Adenocarcinoma (A549) Cells by Triggering Caspase-3/7 Pathway. Inorganic Chemistry.
57(20), 12777-12786.
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Fuentes, N. R., Mlih, M., Barhoumi, R., Fan, Y., Hardin, P., Steele, T. J., ... Chapkin, R. S.
(2018).
Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition. Cancer Research.
78(14), 3899-3912.
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Fan, Y., Fuentes, N. R., Hou, T. Y., Barhoumi, R., Li, X. C., Deutz, N., ... Chapkin, R. S.
(2018).
Remodelling of primary human CD4+ T cell plasma membrane order by n-3 PUFA. British Journal of Nutrition.
119(2), 163-175.
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Morris, D. C., Popp, J. L., Tang, L. K., Gibbs, H. C., Schmitt, E., Chaki, S. P., ... Rivera, G. M.
(2017).
Nck deficiency is associated with delayed breast carcinoma progression and reduced metastasis. Molecular Biology of the Cell.
28(24), 3500-3516.
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Schmitt, E. E., Barhoumi, R., Metz, R. P., & Porter, W. W.
(2017).
Circadian Regulation of Benzo[a]Pyrene Metabolism and DNA Adduct Formation in Breast Cells and the Mouse Mammary Gland. Molecular Pharmacology.
91(3), 178-188.
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Barhoumi, R., Taylor, R., & Tiffany-Castiglioni, E.
(2017).
Lead Uptake and Localization in Glial Cell Cultures. Neuromethods.
124, 151-160.
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Hou, T. Y., Barhoumi, R., Fan, Y., Rivera, G. M., Hannoush, R. N., McMurray, D. N., & Chapkin, R. S.
(2016).
n-3 polyunsaturated fatty acids suppress CD4(+) T cell proliferation by altering phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P2] organization. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.
1858(1), 85-96.
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Chaki, S. P., Barhoumi, R., & Rivera, G. M.
(2015).
Actin remodeling by Nck regulates endothelial lumen formation. Molecular Biology of the Cell.
26(17), 3047-3060.
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Banu, S. K., Stanley, J. A., Sivakumar, K. K., Arosh, J. A., Barhoumi, R., & Burghardt, R. C.
(2015).
Identifying a novel role for X-prolyl aminopeptidase (Xpnpep) 2 in CrVI-induced adverse effects on germ cell nest breakdown and follicle development in rats. Biology of Reproduction.
92(3), 67-18.
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Sridharan, S., Datta, A., Barhoumi, R., Shpati, D., Venkatraj, U., & Venkatraj, V.
(2015).
Threshold Effect of Free Radical Quenching in a Progressive Breast Cancer Cell Line Model. Review of Bioinformatics and Biometrics.
4(1), 1-11.
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Streifel, K. M., Gonzales, A. L., De Miranda, B., Mouneimne, R., Earley, S., & Tjalkens, R.
(2014).
Dopaminergic neurotoxicants cause biphasic inhibition of purinergic calcium signaling in astrocytes. PLoS ONE.
9(11), e110996-e110996.
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Allen, M. J., Fan, Y., Monk, J. M., Hou, T. Y., Barhoumi, R., McMurray, D. N., & Chapkin, R. S.
(2014).
n-3 PUFAs reduce T-helper 17 cell differentiation by decreasing responsiveness to interleukin-6 in isolated mouse splenic CD4 T cells. Journal of Nutrition.
144(8), 1306-1313.
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Pea, B., Barhoumi, R., Burghardt, R. C., Turro, C., & Dunbar, K. R.
(2014).
Confocal fluorescence microscopy studies of a fluorophore-labeled dirhodium compound: visualizing metal-metal bonded molecules in lung cancer (A549) cells. Journal of the American Chemical Society.
136(22), 7861-7864.
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Barhoumi, R., Mouneimne, Y., Chapkin, R. S., & Burghardt, R. C.
(2014).
Effects of fatty acids on benzo[a]pyrene uptake and metabolism in human lung adenocarcinoma A549 cells. PLoS ONE.
9(3), e90908-e90908.
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Laughlin, R. C., Knodler, L. A., Barhoumi, R., Payne, H. R., Wu, J., Gomez, G., ... Adams, L. G.
(2014).
Spatial segregation of virulence gene expression during acute enteric infection with Salmonella enterica serovar Typhimurium. mBio.
5(1), e00946-e00913.
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Kim, W., Barhoumi, R., McMurray, D. N., & Chapkin, R. S.
(2014).
Dietary fish oil and DHA down-regulate antigen-activated CD4+ T-cells while promoting the formation of liquid-ordered mesodomains. British Journal of Nutrition.
111(2), 254-260.
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Li, F., Yu, X., Szynkarski, C. K., Meng, C., Zhou, B., Barhoumi, R., ... Han, G.
(2013).
Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation. PLoS ONE.
8(6), e64771-e64771.
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Chaki, S. P., Barhoumi, R., Berginski, M. E., Sreenivasappa, H., Trache, A., Gomez, S. M., & Rivera, G. M.
(2013).
Nck enables directional cell migration through the coordination of polarized membrane protrusion with adhesion dynamics. Journal of Cell Science.
126(Pt 7), 1637-1649.
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Streifel, K. M., Miller, J., Mouneimne, R., & Tjalkens, R. B.
(2013).
Manganese inhibits ATP-induced calcium entry through the transient receptor potential channel TRPC3 in astrocytes. NeuroToxicology.
34(1), 160-166.
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Li, F., Yu, X., Szynkarski, C. K., Meng, C., Zhou, B., Barhoumi, R., ... Han, G.
(2013).
Correction: Activation of GPER Induces Differentiation and Inhibition of Coronary Artery Smooth Muscle Cell Proliferation. PLoS ONE.
8(7), 10.1371/annotation/ce509358-9f5c-4a8c-9b0d-80.
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Turk, H. F., Barhoumi, R., & Chapkin, R. S.
(2012).
Alteration of EGFR spatiotemporal dynamics suppresses signal transduction. PLoS ONE.
7(6), e39682-e39682.
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Hou, T. Y., Monk, J. M., Fan, Y., Barhoumi, R., Chen, Y. Q., Rivera, G. M., McMurray, D. N., & Chapkin, R. S.
(2012).
n-3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4+ T-cell activation. Biochemical Journal.
443(1), 27-37.
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Tiffany-Castiglioni, E., Barhoumi, R., & Mouneimne, Y.
(2012).
Kohl and surma eye cosmetics as significant sources of lead (Pb) exposure. 2012(1),
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Kolar, S., Barhoumi, R., Jones, C. K., Wesley, J., Lupton, J. R., Fan, Y., & Chapkin, R. S.
(2011).
Interactive effects of fatty acid and butyrate-induced mitochondrial Ca loading and apoptosis in colonocytes. 117(23), 5294-5303.
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Kamkaew, A., Barhoumi, R., Burghardt, R. C., & Burgess, K.
(2011).
Cationic polyfluorenes for intracellular delivery of proteins. Organic and Biomolecular Chemistry.
9(19), 6513-6518.
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Jose, J., Loudet, A., Ueno, Y., Wu, L., Chen, H., Son, D. H., ... Burgess, K.
(2011).
Energy transfer cassettes in silica nanoparticles target intracellular organelles. Organic and Biomolecular Chemistry.
9(10), 3871-3877.
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Kim, K., Burghardt, R., Barhoumi, R., Lee, S., Liu, X., & Safe, S.
(2011).
MDM2 regulates estrogen receptor α and estrogen responsiveness in breast cancer cells. Journal of Molecular Endocrinology.
46(2), 67-79.
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Ibrahim, A., El-Meligy, A., Lungu, G., Fetaih, H., Dessouki, A., Stoica, G., & Barhoumi, R.
(2011).
Curcumin induces apoptosis in a murine mammary gland adenocarcinoma cell line through the mitochondrial pathway. European Journal of Pharmacology.
668(1-2), 127-132.
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Barhoumi, R., Mouneimne, Y., Ramos, E., Morisseau, C., Hammock, B. D., Safe, S., Parrish, A. R., & Burghardt, R. C.
(2011).
Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line. TOXICOLOGY AND APPLIED PHARMACOLOGY.
253(1), 45-56.
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Loudet, A., Ueno, Y., Wu, L., Jose, J., Barhoumi, R., Burghardt, R., & Burgess, K.
(2011).
Organelle-selective energy transfer: a fluorescent indicator of intracellular environment. Bioorganic and Medicinal Chemistry Letters.
21(6), 1849-1851.
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Tiffany-Castiglioni, E., Qian, Y., Barhoumi, R., & Zheng, Y.
(2011).
Determination of metal interactions with the chaperone Hspa5 in human astrocytoma cells and rat astrocyte primary cultures. Methods in molecular biology (Clifton, N.J.).
758, 29-48.
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Ibrahim, A., El-Meligy, A., Fetaih, H., Dessouki, A., Stoica, G., & Barhoumi, R.
(2010).
Effect of curcumin and Meriva on the lung metastasis of murine mammary gland adenocarcinoma. In Vivo: international journal of experimental and clinical pathophysiology and drug research.
24(4), 401-408.
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Yog, R., Barhoumi, R., McMurray, D. N., & Chapkin, R. S.
(2010).
n-3 polyunsaturated fatty acids suppress mitochondrial translocation to the immunologic synapse and modulate calcium signaling in T cells. Journal of Immunology.
184(10), 5865-5873.
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Jose, J., Loudet, A., Ueno, Y., Barhoumi, R., Burghardt, R. C., & Burgess, K.
(2010).
Intracellular imaging of organelles with new water-soluble benzophenoxazine dyes. Organic and Biomolecular Chemistry.
8(9), 2052-2059.
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Vanderlaag, K., Su, Y., Frankel, A. E., Burghardt, R. C., Barhoumi, R., Chadalapaka, G., Jutooru, I., & Safe, S.
(2010).
1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer. BMC Cancer.
10(1), 669.
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Jutooru, I., Chadalapaka, G., Sreevalsan, S., Lei, P., Barhoumi, R., Burghardt, R., & Safe, S.
(2010).
Arsenic trioxide downregulates specificity protein (Sp) transcription factors and inhibits bladder cancer cell and tumor growth. Experimental Cell Research.
316(13), 2174-2188.
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Barhoumi, R., Qian, Y., Burghardt, R. C., & Tiffany-Castiglioni, E.
(2010).
Image analysis of Ca2+ signals as a basis for neurotoxicity assays: promises and challenges. 32(1), 16-24.
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Jian, K., Barhoumi, R., Ko, M. L., & Ko, G.
(2009).
Inhibitory effect of somatostatin-14 on L-type voltage-gated calcium channels in cultured cone photoreceptors requires intracellular calcium. Journal of Neurophysiology.
102(3), 1801-1810.
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Figueiredo, J. F., Barhoumi, R., Raffatellu, M., Lawhon, S. D., Rousseau, B., Burghardt, R. C., ... Adams, L. G.
(2009).
Salmonella enterica serovar Typhimurium-induced internalization and IL-8 expression in HeLa cells does not have a direct relationship with intracellular Ca(2+) levels. Microbes and Infection.
11(10-11), 850-858.
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Wu, L., Loudet, A., Barhoumi, R., Burghardt, R. C., & Burgess, K.
(2009).
Fluorescent cassettes for monitoring three-component interactions in vitro and in living cells. Journal of the American Chemical Society.
131(26), 9156-9157.
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Han, J., Loudet, A., Barhoumi, R., Burghardt, R. C., & Burgess, K.
(2009).
A ratiometric pH reporter for imaging protein-dye conjugates in living cells. Journal of the American Chemical Society.
131(5), 1642-1643.
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Barhoumi, R., Catania, J. M., Parrish, A. R., Awooda, I., Tiffany-Castiglioni, E., Safe, S., & Burghardt, R. C.
(2009).
Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in breast epithelial cell lines. The Journal of Toxicological Sciences.
34(1), 13-25.
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Kim, W., Chapkin, R. S., Barhoumi, R., & Ma, D.
(2009).
A novel role for nutrition in the alteration of functional microdomains on the cell surface. Methods in molecular biology (Clifton, N.J.).
579, 261-270.
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Martinez, J. G., Huang, J. Z., Burghardt, R. C., Barhoumi, R., & Carroll, R. J.
(2009).
Use of multiple singular value decompositions to analyze complex intracellular calcium ion signals. Annals of Applied Statistics.
3(4), 1467-1492.
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Forough, R., Miller, M. W., Mattox, M., Dunlap, W., Ambrus, A., Barhoumi, R., Heaps, C. L., & Parker, J. L.
(2008).
Enhanced myocardial vascularity and contractility by novel FGF-1 transgene in a porcine model of chronic coronary occlusion. Journal of Tehran University Heart Center.
3(4), 197-204.
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Loudet, A., Han, J., Barhoumi, R., Pellois, J., Burghardt, R. C., & Burgess, K.
(2008).
Non-covalent delivery of proteins into mammalian cells. Organic and Biomolecular Chemistry.
6(24), 4516-4522.
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Kim, W., Fan, Y., Barhoumi, R., Smith, R., McMurray, D. N., & Chapkin, R. S.
(2008).
n-3 polyunsaturated fatty acids suppress the localization and activation of signaling proteins at the immunological synapse in murine CD4+ T cells by affecting lipid raft formation. Journal of Immunology.
181(9), 6236-6243.
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Ly, L. H., Barhoumi, R., Cho, S. H., Franzblau, S. G., & McMurray, D. N.
(2008).
Vaccination with Bacille-Calmette Gurin promotes mycobacterial control in guinea pig macrophages infected in vivo. Journal of Infectious Diseases.
198(5), 768-771.
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Wu, F., Khan, S., Wu, Q., Barhoumi, R., Burghardt, R., & Safe, S.
(2008).
Ligand structure-dependent activation of estrogen receptor alpha/Sp by estrogens and xenoestrogens. Journal of Steroid Biochemistry and Molecular Biology.
110(1-2), 104-115.
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Kolar, S., Barhoumi, R., Callaway, E. S., Fan, Y., Wang, N., Lupton, J. R., & Chapkin, R. S.
(2007).
Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes. American Journal of Physiology - Gastrointestinal and Liver Physiology.
293(5), G935-G943.
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Kolar, S., Barhoumi, R., Lupton, J. R., & Chapkin, R. S.
(2007).
Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2+ accumulation. Cancer Research.
67(11), 5561-5568.
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Qian, Y., Venkatraj, J., Barhoumi, R., Pal, R., Datta, A., Wild, J. R., & Tiffany-Castiglioni, E.
(2007).
Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines. TOXICOLOGY AND APPLIED PHARMACOLOGY.
219(2-3), 162-171.
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Barhoumi, R., Burghardt, R. C., Qian, Y., & Tiffany-Castiglioni, E.
(2007).
Effects of propofol on intracellular Ca2+ homeostasis in human astrocytoma cells. BRAIN RESEARCH.
1145(1), 11-18.
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Khan, S., Barhoumi, R., Burghardt, R., Liu, S., Kim, K., & Safe, S.
(2006).
Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells. Molecular Endocrinology.
20(9), 2199-2214.
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Forough, R., Weylie, B., Collins, C., Parker, J. L., Zhu, J., Barhoumi, R., & Watson, D. K.
(2006).
Transcription factor Ets-1 regulates fibroblast growth factor-1-mediated angiogenesis in vivo: role of Ets-1 in the regulation of the PI3K/AKT/MMP-1 pathway. Journal of Vascular Research.
43(4), 327-337.
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Seo, J., Barhoumi, R., Johnson, A. E., Lupton, J. R., & Chapkin, R. S.
(2006).
Docosahexaenoic acid selectively inhibits plasma membrane targeting of lipidated proteins. The FASEB Journal.
20(6), 770-772.
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Abdelrahim, M., Ariazi, E., Kim, K., Khan, S., Barhoumi, R., Burghardt, R., ... Safe, S.
(2006).
3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Research.
66(4), 2459-2467.
-
Barhoumi, R., Awooda, I., Mouneimne, Y., Safe, S., & Burghardt, R. C.
(2006).
Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells. Toxicology Letters.
165(2), 133-141.
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Vanderlaag, K., Samudio, I., Burghardt, R., Barhoumi, R., & Safe, S.
(2006).
Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM. Cancer Letters.
236(2), 198-212.
-
Tjalkens, R. B., Zoran, M. J., Mohl, B., & Barhoumi, R.
(2006).
Manganese suppresses ATP-dependent intercellular calcium waves in astrocyte networks through alteration of mitochondrial and endoplasmic reticulum calcium dynamics. BRAIN RESEARCH.
1113(1), 210-219.
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Ng, Y., Barhoumi, R., Tjalkens, R. B., Fan, Y., Kolar, S., Wang, N., Lupton, J. R., & Chapkin, R. S.
(2005).
The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes. Carcinogenesis.
26(11), 1914-1921.
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Ottinger, S., Barhoumi, R., McKenzie, K. S., McDonald, T., Burghardt, R., Huebner, H. J., & Phillips, T. D.
(2005).
FIA/MS analysis of temporally ozonated benzo[a]pyrene and pyrene and their reaction products: inhibition of gap junction-mediated intercellular communication. Chemosphere.
60(8), 1025-1033.
-
Kim, K., Barhoumi, R., Burghardt, R., & Safe, S.
(2005).
Analysis of estrogen receptor alpha-Sp1 interactions in breast cancer cells by fluorescence resonance energy transfer. Molecular Endocrinology.
19(4), 843-854.
-
Partridge, C. R., Williams, E. S., Barhoumi, R., Tadesse, M. G., Johnson, C. D., Lu, K. P., ... Ramos, K. S.
(2005).
Novel genomic targets in oxidant-induced vascular injury. Journal of Molecular and Cellular Cardiology.
38(6), 983-996.
-
Pietrantonio, P. V., Jagge, C., Taneja-Bageshwar, S., Nachman, R. J., & Barhoumi, R.
(2005).
The mosquito Aedes aegypti (L.) leucokinin receptor is a multiligand receptor for the three Aedes kinins. INSECT MOLECULAR BIOLOGY.
14(1), 55-67.
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Fan, Y., Ly, L. H., Barhoumi, R., McMurray, D. N., & Chapkin, R. S.
(2004).
Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 production. Journal of Immunology.
173(10), 6151-6160.
-
Mnaimneh, S., Damaj, M., Barhoumi, R., Mouneimne, Y., Geffard, M., Veyret, B., & Vincendeau, P.
(2004).
Evidence for nitric oxide involvement in experimental autoimmune encephalomyelitis and adjuvant-induced arthritis in Lewis rat. Pain Clinic.
16(3), 229-243.
-
Barhoumi, R., Faske, J., Liu, X. H., & Tjalkens, R. B.
(2004).
Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB (vol 122, pg 167, 2004). 126(1), 103-105.
-
Barhoumi, R., Faske, J., Liu, X., & Tjalkens, R. B.
(2004).
Manganese potentiates lipopolysaccharide-induced expression of NOS2 in C6 glioma cells through mitochondrial-dependent activation of nuclear factor kappaB. 122(2), 167-179.
-
Sanders, L. M., Henderson, C. E., Hong, M. Y., Barhoumi, R., Burghardt, R. C., Wang, N., ... Lupton, J. R.
(2004).
An increase in reactive oxygen species by dietary fish oil coupled with the attenuation of antioxidant defenses by dietary pectin enhances rat colonocyte apoptosis. Journal of Nutrition.
134(12), 3233-3238.
-
Sanders, L. M., Henderson, C. E., Hong, M. Y., Barhoumi, R., Burghardt, R. C., Carroll, R. J., ... Lupton, J. R.
(2004).
Pro-oxidant environment of the colon compared to the small intestine may contribute to greater cancer susceptibility. Cancer Letters.
208(2), 155-161.
-
Cizmas, L., Barhoumi, R., Burghardt, R. C., Reeves, W. R., He, L., McDonald, T. J., & Donnelly, K. C.
(2003).
A comparison of two methods for fractionating complex mixtures in preparation for toxicity analysis. Journal of Toxicology and Environmental Health - Part A.
66(14), 1351-1370.
-
Holmes, S. P., Barhoumi, R., Nachman, R. J., & Pietrantonio, P. V.
(2003).
Functional analysis of a G protein-coupled receptor from the southern cattle tick Boophilus microplus (Acari: Ixodidae) identifies it as the first arthropod myokinin receptor. INSECT MOLECULAR BIOLOGY.
12(1), 27-38.
-
Mnaimneh, S., Damaj, M., Barhoumi, R., Mouneimne, Y., Veyret, B., Geffard, M., & Vincendeau, P.
(2003).
Circulating antibodies directed against nitrosylated antigens in trypanosome-infected mice. Experimental Parasitology.
105(3-4), 241-247.
-
Hong, M. S., Hong, S. J., Barhoumi, R., Burghardt, R. C., Donnelly, K. C., Wild, J. R., Venkatraj, V., & Tiffany-Castiglioni, E.
(2003).
Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds. TOXICOLOGY AND APPLIED PHARMACOLOGY.
186(2), 110-118.
-
Cizmas, L., Barhoumi, R., Burghardt, R. C., Reeves, W. R., He, L. Y., McDonald, T. J., & Donnelly, K. C.
(2003).
A comparison of two methods for fractionating complex mixtures in preparation for toxicity analysis. Journal of Toxicology and Environmental Health - Part A.
66(14), 1351-1370.
-
Hong, M. Y., Chapkin, R. S., Barhoumi, R., Burghardt, R. C., Turner, N. D., Henderson, C. E., ... Lupton, J. R.
(2002).
Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes. Carcinogenesis.
23(11), 1919-1925.
-
Barhoumi, R., Mouneimne, Y., Awooda, I., Safe, S. H., Donnelly, K. C., & Burghardt, R. C.
(2002).
Characterization of calcium oscillations in normal and benzo[a]pyrene-treated clone 9 cells. TOXICOLOGICAL SCIENCES.
68(2), 444-450.
-
Botos, J., Barhoumi, R., Burghardt, R., & Kochevar, D. T.
(2002).
Rb localization and phosphorylation kinetics correlate with the cellular phenotype of cultured breast adenocarcinoma cells. In Vitro Cellular and Developmental Biology - Animal.
38(4), 235-241.
-
Mealey, K. L., Barhoumi, R., Burghardt, R. C., Safe, S., & Kochevar, D. T.
(2002).
Doxycycline induces expression of P glycoprotein in MCF-7 breast carcinoma cells. 46(3), 755-761.
-
Chapkin, R. S., Hong, M. Y., Fan, Y., Davidson, L. A., Sanders, L. M., Henderson, C. E., ... Lupton, J. R.
(2002).
Dietary n-3 PUFA alter colonocyte mitochondrial membrane composition and function. Lipids.
37(2), 193-199.
-
Cossio-Bayugar, R., Barhoumi, R., Burghardt, R. C., Wagner, G. G., & Holman, P. J.
(2002).
Basal cellular alterations of esterase, glutathione, glutathione S-transferase, intracellular calcium, and membrane potentials in coumaphos-resistant Boophilus microplus (Acari: Ixodidae) cell lines. 72(1), 1-9.
-
Rigby, S. L., Barhoumi, R., Burghardt, R. C., Colleran, P., Thompson, J. A., Varner, D. D., ... Delp, M. D.
(2001).
Mares with delayed uterine clearance have an intrinsic defect in myometrial function. Biology of Reproduction.
65(3), 740-747.
-
Reeves, W. R., Barhoumi, R., Burghardt, R. C., Lemke, S. L., Mayura, K., McDonald, T. J., Phillips, T. D., & Donnelly, K. C.
(2001).
Evaluation of methods for predicting the toxicity of polycyclic aromatic hydrocarbon mixtures. Environmental Science and Technology.
35(8), 1630-1636.
-
Samudio, I., Vyhlidal, C., Wang, F., Stoner, M., Chen, I., Kladde, M., ... Safe, S.
(2001).
Transcriptional activation of deoxyribonucleic acid polymerase alpha gene expression in MCF-7 cells by 17 beta-estradiol. ENDOCRINOLOGY.
142(3), 1000-1008.
-
Barhoumi, R., Mouneimne, Y., Ramos, K. S., Safe, S. H., Phillips, T. D., Centonze, V. E., ... Burghardt, R. C.
(2000).
Analysis of benzo[a]pyrene partitioning and cellular homeostasis in a rat liver cell line. TOXICOLOGICAL SCIENCES.
53(2), 264-270.
-
Fan, Y., Zhang, J., Barhoumi, R., Burghardt, R. C., Turner, N. D., Lupton, J. R., & Chapkin, R. S.
(1999).
Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells. American Journal of Physiology - Cell Physiology.
277(2 46-2),
-
Fan, Y. Y., Zhang, J., Barhoumi, R., Burghardt, R. C., Turner, N. D., Lupton, J. R., & Chapkin, R. S.
(1999).
Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells. AMERICAN JOURNAL OF PHYSIOLOGY.
277(2), C310-C319.
-
Burghardt, R. C., Barhoumi, R., Sanborn, B. M., & Andersen, J.
(1999).
Oxytocin-induced Ca2+ responses in human myometrial cells. Biology of Reproduction.
60(4), 777-782.
-
Gauntt, C., Busbee, D., Wood, H. J., Reyna, S., Barhoumi, R., Burghardt, R., McAnalley, W., & McDaniel, H. R.
(1999).
A glyconutritional mixture (Ambrotose) provides some amelioration to mice with coxsackievirus-induced pancreatitis. AGE.
22(4), 149-158.
-
Fan, Y. Y., Zhang, J. H., Barhoumi, R., Burghardt, R. C., Turner, N. D., Lupton, J. R., & Chapkin, R. S.
(1999).
Antagonism of CD95 signaling blocks butyrate induction of apoptosis in young adult mouse colonic cells. American Journal of Physiology - Cell Physiology.
277(2), C310-C319.
-
Mealey, K. L., Barhoumi, R., Burghardt, R. C., McIntyre, B. S., Sylvester, P. W., Hosick, H. L., & Kochevar, D. T.
(1999).
Immunosuppressant inhibition of P-glycoprotein function is independent of drug-induced suppression of peptide-prolyl isomerase and calcineurin activity. Cancer Chemotherapy and Pharmacology.
44(2), 152-158.
-
Busbee, D., Barhoumi, R., Burghardt, R. C., Gauntt, C., McAnalley, B., & McDaniel, H. R.
(1999).
Protection from glutathione depletion by a glyconutritional mixture of saccharides. AGE.
22(4), 159-165.
-
Hutchinson, R. W., Barhoumi, R., Miles, J. M., & Burghardt, R. C.
(1998).
Attenuation of gossypol cytotoxicity by cyclic AMP in a rat liver cell line. TOXICOLOGY AND APPLIED PHARMACOLOGY.
151(2), 311-318.
-
Day, W. E., Bowen, J. A., Barhoumi, R., Bazer, F. W., & Burghardt, R. C.
(1998).
Endometrial connexin expression in the mare and pig: Evidence for the suppression of cell-cell communication in uterine luminal epithelium. Anatomical Record.
251(3), 277-285.
-
Day, W. E., Bowen, J. A., Barhoumi, R., Bazer, F. W., & Burghardt, R. C.
(1998).
Endometrial connexin expression in the mare and pig: evidence for the suppression of cell-cell communication in uterine luminal epithelium. Anatomical Record.
251(3), 277-285.
-
Legare, M. E., Barhoumi, R., Hebert, E., Bratton, G. R., Burghardt, R. C., & Tiffany-Castiglioni, E.
(1998).
Analysis of Pb2+ entry into cultured astroglia. TOXICOLOGICAL SCIENCES.
46(1), 90-100.
-
Thompson, D. C., Barhoumi, R., & Burghardt, R. C.
(1998).
Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays. TOXICOLOGY AND APPLIED PHARMACOLOGY.
149(1), 55-63.
-
Mealey, K. L., Barhoumi, R., Rogers, K., & Kochevar, D. T.
(1998).
Doxorubicin induced expression of P-glycoprotein in a canine osteosarcoma cell line. Cancer Letters.
126(2), 187-192.
-
Legare, M. E., Hanneman, W. H., Barhoumi, R., & Tiffany-Castiglioni, E.
(1997).
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure in primary rat astroglia: identification of biochemical and cellular targets. NeuroToxicology.
18(2), 515-524.
-
Burghardt, R. C., & Barhoumi, R.
(1997).
Analysis of Mechanisms of Cellular Injury on the Micrometer Scale. Microscopy and Microanalysis.
3(S2), 37-38.
-
Zoran, D. L., Barhoumi, R., Burghardt, R. C., Chapkin, R. S., & Lupton, J. R.
(1997).
Diet and carcinogen alter luminal butyrate concentration and intracellular pH in isolated rat colonocytes. Nutrition and Cancer.
27(3), 222-230.
-
Meola, S., Meola, R., Barhoumi, R., Miles, J. M., & Burghardt, R. C.
(1997).
Laser cytometric analysis of permethrin toxicity in insect and mammalian epithelial cells. Toxic Substance Mechanisms.
16(3), 237-249.
-
Hoivik, D., Wilson, C., Wang, W., Willett, K., Barhoumi, R., Burghardt, R., & Safe, S.
(1997).
Studies on the relationship between estrogen receptor content, glutathione S-transferase pi expression, and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin and drug resistance in human breast cancer cells. Archives of Biochemistry and Biophysics.
348(1), 174-182.
-
Burghardt, R. C., Barhoumi, R., Stickney, M., Monga, M., Ku, C. Y., & Sanborn, B. M.
(1996).
Correlation between connexin43 expression, cell-cell communication, and oxytocin-induced Ca2+ responses in an immortalized human myometrial cell line. Biology of Reproduction.
55(2), 433-438.
-
Barhoumi, R., Mouneimne, Y., Phillips, T. D., Safe, S. H., & Burghardt, R. C.
(1996).
Alteration of oxytocin-induced calcium oscillations in clone 9 cells by toxin exposure. Fundamental and applied toxicology : official journal of the Society of Toxicology.
33(2), 220-228.
-
BARHOUMI, R., & BURGHARDT, R. C.
(1996).
Kinetic Analysis of the Chronology of Patulin- and Gossypol-Induced Cytotoxicity in Vitro. TOXICOLOGICAL SCIENCES.
30(2), 290-297.
-
Barhoumi, R., & Burghardt, R. C.
(1996).
Kinetic analysis of the chronology of patulin- and gossypol-induced cytotoxicity in vitro. Fundamental and applied toxicology : official journal of the Society of Toxicology.
30(2), 290-297.
-
Hanneman, W. H., Legare, M. E., Barhoumi, R., Burghardt, R. C., Safe, S., & Tiffany-Castiglioni, E.
(1996).
Stimulation of calcium uptake in cultured rat hippocampal neurons by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology.
112(1), 19-28.
-
Tiffany-Castiglioni, E., Legare, M. E., Schneider, L. A., Harris, E. D., Barhoumi, R., Zmudzki, J., Qian, Y., & Burghardt, R. C.
(1996).
[10] Heavy Metal Effects on Glia. Methods in Neurosciences.
30(C), 135-166.
-
BARHOUMI, R., MOUNEIMNE, Y., PHILLIPS, T. D., SAFE, S. H., & BURGHARDT, R. C.
(1996).
Alteration of Oxytocin-Induced Calcium Oscillations in Clone 9 Cells by Toxin Exposure. TOXICOLOGICAL SCIENCES.
33(2), 220-228.
-
Burghardt, R. C., Barhoumi, R., Sewall, T. C., & Bowen, J. A.
(1995).
Cyclic AMP induces rapid increases in gap junction permeability and changes in the cellular distribution of connexin43. Journal of Membrane Biology: an international journal for studies on the structure, function and genesis of biomembranes.
148(3), 243-253.
-
BARHOUMI, R., BAILEY, R. H., HUTCHINSON, R. W., BOWEN, J. A., & BURGHARDT, R. C.
(1995).
Enhancement of Melphalan Toxicity by Octanol in Ovarian Adenocarcinoma Cell Lines: Effects of Altered Cell-Cell Communication, Glutathione Levels, and Plasma Membrane Fluidity. TOXICOLOGICAL SCIENCES.
25(1), 70-79.
-
Aucoin, M. M., Barhoumi, R., Kochevar, D. T., Granger, H. J., & Burghardt, R. C.
(1995).
Oxidative injury of coronary venular endothelial cells depletes intracellular glutathione and induces HSP 70 mRNA. AMERICAN JOURNAL OF PHYSIOLOGY.
268(4 Pt 2), H1651-H1658.
-
Barhoumi, R., Bailey, R. H., & Burghardt, R. C.
(1995).
Kinetic analysis of glutathione in anchored cells with monochlorobimane. Cytometry.
19(3), 226-234.
-
Zenger, E., Collisson, E. W., Barhoumi, R., Burghardt, R. C., Danave, I. R., & Tiffany-Castiglioni, E.
(1995).
Laser cytometric analysis of FIV-induced injury in astroglia. Glia.
13(2), 92-100.
-
Barhoumi, R., Bailey, H. R., Hutchinson, R. W., Bowen, J. A., & Burghardt, R. C.
(1995).
Enhancement of melphalan toxicity by octanol in ovarian adenocarcinoma cell lines: effects of altered cell-cell communication, glutathione levels, and plasma membrane fluidity. Fundamental and applied toxicology : official journal of the Society of Toxicology.
25(1), 70-79.
-
Hutchinson, R. W., Barhoumi, R., & Burghardt, R. C.
(1995).
Laser cytometric analysis of gossypol-induced cytotoxicity. Toxic Substance Mechanisms.
14(3), 169-184.
-
Danave, I. R., Tiffany-Castiglioni, E., Zenger, E., Barhoumi, R., Burghardt, R. C., & Collisson, E. W.
(1994).
Feline immunodeficiency virus decreases cell-cell communication and mitochondrial membrane potential. Journal of Virology.
68(10), 6745-6750.
-
Spainhour, C. B., Mayura, K., Barhoumi, R., Burghardt, R. G., & Phillips, T. D.
(1994).
A comparison of the findings and predictions of toxicity from four different in vitro bioassays with the results of in vivo studies for 3,5-dichlorophenol. Toxicology Letters.
74, 82-82.
-
Moore, M., Wang, X., Lu, Y. F., Wormke, M., Craig, A., Gerlach, J. H., ... Safe, S.
(1994).
Benzo[a]pyrene-resistant MCF-7 human breast cancer cells. A unique aryl hydrocarbon-nonresponsive clone. Journal of Biological Chemistry.
269(16), 11751-11759.
-
TIFFANYCASTIGLIONI, E., HANNEMAN, W. H., LEGARE, M. E., HONG, S. J., BARHOUMI, R., BURGHARDT, R. C., & SAFE, S.
(1994).
CONGENER-SPECIFIC EFFECTS OF DIOXINS ON NEURAL CELLS. Journal of Neurochemistry.
62, S28-S28.
-
Barhoumi, R., Bowen, J. A., Stein, L. S., Echols, J., & Burghardt, R. C.
(1993).
Concurrent analysis of intracellular glutathione content and gap junctional intercellular communication. Cytometry.
14(7), 747-756.
-
ELLINGTON, J. E., VARNER, D. D., BURGHARDT, R. C., MEYERSWALLEN, V. N., BARHOUMI, R., BRINSKO, S. P., & BALL, B. A.
(1993).
CELL-TO-CELL COMMUNICATION OF EQUINE UTERINE TUBE (OVIDUCT) CELLS AS DETERMINED BY ANCHORED CELL ANALYSIS IN CULTURE. Animal Reproduction Science.
30(4), 313-324.
-
BURGHARDT, R. C., BARHOUMI, R., & DOOKWAH, H.
(1993).
ENDOCRINE REGULATION OF MYOMETRIAL GAP-JUNCTIONS AND THEIR ROLE IN PARTURITION. Seminars in reproductive endocrinology.
11(3), 250-260.
-
Legare, M. E., Barhoumi, R., Burghardt, R. C., & Tiffany-Castiglioni, E.
(1993).
Low-level lead exposure in cultured astroglia: identification of cellular targets with vital fluorescent probes. NeuroToxicology.
14(2-3), 267-272.
-
Dookwah, H. D., Barhoumi, R., Narasimhan, T. R., Safe, S. H., & Burghardt, R. C.
(1992).
Gap junctions in myometrial cell cultures: evidence for modulation by cyclic adenosine 3':5'-monophosphate. Biology of Reproduction.
47(3), 397-407.
-
Burghardt, R. C., Barhoumi, R., Lewis, E. H., Bailey, R. H., Pyle, K. A., Clement, B. A., & Phillips, T. D.
(1992).
Patulin-induced cellular toxicity: a vital fluorescence study. TOXICOLOGY AND APPLIED PHARMACOLOGY.
112(2), 235-244.
-
Mouneimne, Y., Tosi, P. F., Barhoumi, R., & Nicolau, C.
(1991).
Electroinsertion of xeno proteins in red blood cell membranes yields a long lived protein carrier in circulation. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.
1066(1), 83-89.
-
Mouneimne, Y., Barhoumi, R., Myers, T., Slogoff, S., & Nicolau, C.
(1990).
Stable rightward shifts of the oxyhemoglobin dissociation curve induced by encapsulation of inositol hexaphosphate in red blood cells using electroporation. FEBS Letters.
275(1-2), 117-120.
-
Mouneimne, Y., Tosi, P. F., Barhoumi, R., & Nicolau, C.
(1990).
Electroinsertion of full length recombinant CD4 into red blood cell membrane. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.
1027(1), 53-58.
-
Nicolau, C., Tosi, P. F., Arvinte, T., Mouneimne, Y., Cudd, A., Sneed, L., ... Barhoumi, R.
(1990).
CD4 inserted in red blood cell membranes or reconstituted in liposome bilayers as a potential therapeutic agent against AIDS. Progress in clinical and biological research.
343, 147-177.
-
Sakolish, C., Weber, E. J., Kelly, E. J., Himmelfarb, J., Mouneimne, R., Grimm, F. A., ... Rusyn, I.
Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip. Scientific Reports.
8(1), 14882.
-
Elswood, J., Pearson, S. J., Payne, H. R., Barhoumi, R., Rijnkels, M., & W Porter, W.
(2021).
Autophagy regulates functional differentiation of mammary epithelial cells. Autophagy.
17(2), 420-438.
-
chapter
-
Mouneimne, Y., Tosi, P., Barhoumi, R., & Nicolau, C.
(1992).
Electroinsertion: An Electrical Method for Protein Implantation into Cell Membranes. Guide to Electroporation and Electrofusion.
(pp. 327-346).
Elsevier.
-
Mouneimne, Y., Tosi, P., Barhoumi, R., & Nicolau, C.
(1992).
20 Electroinsertion: An Electrical Method for Protein Implantation into Cell Membranes. Guide to Electroporation and Electrofusion.
(pp. 327-346).
Elsevier.
-
Mouneimne, Y., Tosi, P., Barhoumi, R., & Nicolau, C.
(1992).
20 Electroinsertion: An Electrical Method for Protein Implantation into Cell Membranes. Guide to Electroporation and Electrofusion.
(pp. 327-346).
Elsevier.
-
Mouneimne, Y., Tosi, P., Barhoumi, R., & Nicolau, C.
(1992).
Electroinsertion: An Electrical Method for Protein Implantation into Cell Membranes. Guide to Electroporation and Electrofusion.
(pp. 327-346).
Elsevier.
-
conference paper
-
Salinas, M. L., Fuentes, N. R., Barhoumi, R., & Chapkin, R. S.
(2017).
Dietary amphiphilic polyphenols modulate the biophysical properties of plasma membrane organization and membrane-dependent macropinocytosis. Cancer Research.
255-255.
-
Fuentes, N. R., Barhoumi, R., Mlih, M., Karpac, J., Hardin, P., Steele, T., ... Chapkin, R. S.
(2017).
Plasma membrane lipid therapy: disruption of oncogenic Ras spatiotemporal organization by membrane-targeted dietary bioactives (MTDB). Cancer Research.
179-179.
-
Chaki, S. P., Barhoumi, R., & Rivera, G. M.
(2015).
Nck Promotes Podosome Formation and Function in Vascular Endothelial Cells. Circulation Research.
-
Hou, T., Barhoumi, R., Rivera, G., McMurray, D., & Chapkin, R.
(2014).
Lipophilic natural compounds (n-3 polyunsaturated fatty acids) modulate plasma membrane organization in mouse CD4(+) T cells. The FASEB Journal.
-
Allen, M. J., Fan, Y., Monk, J., Hou, T., Barhoumi, R., McMurray, D., & Chapkin, R.
(2014).
n-3 Polyunsaturated fatty acids reduce Th17 polarization by decreasing responsiveness to interleukin-6. The FASEB Journal.
-
Pena, B., Barhoumi, R., & Dunbar, K. R.
(2014).
Anticancer properties of Ruthenium(II) polypyridine compounds with anionic N boolean AND O-donor bidentate ligands. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
Chaki, S. P., Barhoumi, R., & Rivera, G. M.
(2014).
Nck Regulate Endothelial Cell Morphogenesis by Modulating the Activity of Cdc42. Molecular Biology of the Cell.
-
Turk, H. F., Barhoumi, R., Lupton, J. R., & Chapkin, R. S.
(2011).
A novel role for n-3 polyunsaturated fatty acids in inhibition of EGFR signal transduction. The FASEB Journal.
349.4-349.4.
-
Chaki, S. P., Barhoumi, R., Yog, R., Berginski, M. E., Gomez, S. M., & Rivera, G. M.
(2011).
Nck Is Required for Focal Adhesion Maturation and Polarized Cell Motility. Molecular Biology of the Cell.
-
Laughlin, R. C., Knodler, L. A., Payne, H. R., Mouneimne, R. B., Steele-Mortimer, O., & Adams, L. G.
(2011).
Salmonella enterica Typhimurium associated with enterocyte extrusion in an in vivo bovine enteric infection model. Molecular Biology of the Cell.
-
Yog, R., Barhoumi, R., McMurray, D. N., & Chapkin, R. S.
(2009).
n-3 Polyunsaturated Fatty Acids Suppress T-Cell Mitochondrial Translocation to the Immunological Synapse. The FASEB Journal.
910.20-910.20.
-
Kolar, S., Barhoumi, R., Callaway, E. S., Lupton, J. R., & Chapkin, R. S.
(2007).
Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial calcium accumulation. The FASEB Journal.
A158-A158.
-
Barhoumi, R., & Tiffany-Castilioni, E.
(2006).
Use of Ca2+ modeling as a predictive measure of neurotoxicity. NeuroToxicology.
1175-1175.
-
Kolar, S., Barhoumi, R., Lupton, J. R., & Chapkin, R. S.
(2006).
Chemoprotective nutrients modulate intracellular calcium compartmentalization and store-operated channel entry to induce colonocyte apoptosis. The FASEB Journal.
A1001-A1001.
-
Chapkin, R. S., Ng, Y., Barhoumi, R., Tjalkens, R. B., Fan, Y. Y., Kolar, S., Wang, N. Y., & Lupton, J. R.
(2006).
The role of docosahexaenoic acid in mediating mitochondrial membrane tipid oxidation and apoptosis in colonocytes. Prostaglandins and Other Lipid Mediators.
172-173.
-
Seo, J. M., Barhoumi, R., Lupton, J. R., & Chapkin, R. S.
(2005).
Docosahexaenoic acid-induced inhibition of plasma membrane targeting is reversible and selective to lipidated cytosolic proteins. The FASEB Journal.
A1455-A1455.
-
Sanders, L. M., Henderson, C. E., Hong, M. Y., Barhoumi, R., Burghardt, R. C., Carroll, R. J., ... Lupton, J. R.
(2004).
Dietary alteration of reactive oxygen species (ROS) and antioxidant enzyme activity in rat colonocytes is age-dependent. The FASEB Journal.
A10-A11.
-
Ng, Y. V., Barhoumi, R., Tjalkens, R. B., Lupton, J. R., & Chapkin, R. S.
(2004).
Docosahexaenoic acid and butyrate synergistically enhance mitochondrial membrane lipid oxidation and the dissipation of membrane potential. The FASEB Journal.
A896-A897.
-
Burghardt, R. C., Awooda, I., Safe, S. H., Donnelly, K. C., & Barhoumi, R.
(2004).
Effects of benzo(a)pyrene on oxytocin-induced calcium oscillations in human myometrial cells. Biology of Reproduction.
111-111.
-
Holderman, M. T., Partridge, C. R., Barhoumi, R., & Ramos, K. S.
(2003).
Expression and localization of P70 albumin precursor protein and phi AP3 in oxidatively stressed vascular smooth muscle cells. TOXICOLOGICAL SCIENCES.
11-11.
-
Sanders, L. M., Henderson, C. E., Hong, M. Y., Barhoumi, R., Burghardt, R. C., Murphy, M. E., ... Lupton, J. R.
(2003).
A diet of fish oil and pectin reduces colonic antioxidant enzymes creating an environment permissive for ROS-induced apoptosis. The FASEB Journal.
A1154-A1154.
-
Newton, A. H., Covert, K. L., Barhoumi, R., Turner, N. D., Sanders, L. M., Hong, M. Y., ... Lupton, J. R.
(2003).
Dietary fish oil plus butyrate protect against colon cancer by increasing reactive oxygen species and decreasing mitochondrial membrane potential in the promotion stage of tumorigenesis. The FASEB Journal.
A1154-A1154.
-
Partridge, C. R., Williams, E. S., Lu, K. P., Chao, S., Johnson, C. D., Barhoumi, R., ... Ramos, K. S.
(2003).
Genomic and immunofluorescence analysis of interactive gene networks in oxidant induced atherogenesis. TOXICOLOGICAL SCIENCES.
95-95.
-
Seo, J., Barhoumi, R., Davidson, L. A., Burghardt, R. C., Lupton, J. R., & Chapkin, R. S.
(2002).
DHA decreases plasma membrane localization of Ras in colonic epithelial cells. The FASEB Journal.
A370-A370.
-
Sanders, L. M., Henderson, C. E., Hong, M. Y., Barhoumi, R., Burghardt, R. C., Spinka, C. M., ... Lupton, J. R.
(2002).
Dietary fish oil and pectin protect against oxidative DNA damage in rat intestinal epithelial cells due to heightened apoptosis induced by reactive oxygen species. The FASEB Journal.
A371-A371.
-
Henderson, C. E., Sanders, L. M., Hong, M. Y., Taddeo, S. S., Barhoumi, R., Spinka, C. M., ... Lupton, J. R.
(2001).
Diet induced rat colonic reactive oxygen species production is age dependent. The FASEB Journal.
A400-A400.
-
Hong, M. Y., Henderson, C. E., Sanders, L. M., Taddeo, S. S., Barhoumi, R., Fan, Y. Y., ... Lupton, J. R.
(2001).
Dietary fish oil may protect against colon cancer by altering mitochondrial function thereby creating a permissive environment for butyrate-induced apoptosis. The FASEB Journal.
A61-A61.
-
Fan, Y. Y., Hong, M. Y., Davidson, L. A., Sanders, L. M., Henderson, C. E., Turner, N. D., ... Chapkin, R. S.
(2001).
Dietary lipid source alters fatty acid composition in mitochondrial membrane phospholipids and modulates mitochondrial function in rat colonocytes. The FASEB Journal.
A283-A283.
-
Legare, M. E., Hanneman, W. H., Barhoumi, R., Burghardt, R. C., & Tiffany-Castiglioni, E.
(2000).
2,3,7,8-Tetrachlorodibenzo-p-dioxin alters hippocampal astroglia-neuronal gap junctional communication. NeuroToxicology.
1109-1116.
-
Busbee, D., Mouneimne, R., Burghardt, R., Gauntt, C., McAnalley, B. H., & McDaniel, H. R.
(1999).
Protection from glutathione depletion by a glyco-nutritional. AGE.
121-121.
-
Burghardt, R. C., Barhoumi, R., & Mouneimne, Y.
(1999).
Estradiol modulation of oxytocin-induced intracellular calcium oscillations in an immortalized human myometrial cell line (PHM1-41). Biology of Reproduction.
142-142.
-
Barhoumi, R., Burghardt, R. C., Busbee, D. L., & McDaniel, H. R.
(1998).
Glyconutrients increase reduced glutathione (GtH+) levels in murine liver cells. Journal of Investigative Medicine.
193A-193A.
-
Dippel, W. W., Barhoumi, R., Burghardt, R. C., & Harms, P. G.
(1997).
Calcium/calmodulin protein kinase II regulation of LHRH release from GT1-1 cells. The FASEB Journal.
3036-3036.
-
Burghardt, R. C., Barhoumi, R., & Sanborn, B. M.
(1997).
Oxytocin-induced calcium oscillations in immortalized human myometrial cells. Biology of Reproduction.
228-228.
-
Zoran, D., Barhoumi, R., Burghardt, R. C., Chang, W., Chapkin, R. S., & Lupton, J. R.
(1996).
Diet and carcinogen alter luminal butyrate concentration and intracellular pH in colonocytes. The FASEB Journal.
3014-3014.
-
Burghardt, R. C., Bowen, J. A., Day, W. E., Barhoumi, R., Bazer, F. W., Glasser, S. R., & Newton, G. R.
(1996).
Comparative analysis of gap junction protein in expression in porcine, equine, and caprine endometrium. Biology of Reproduction.
472-472.
-
BURGHARDT, R. C., BARHOUMI, R., STICKNEY, M., BOWEN, J., SANBORN, B. M., MONGA, M., & KU, C. Y.
(1995).
MODULATION OF GAP-JUNCTIONS IN AN IMMORTALIZED HUMAN MYOMETRIAL CELL-LINE. Biology of Reproduction.
146-146.
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BURGHARDT, R. C., DAY, W., SCHWAB, C. A., BARHOUMI, R., BLANCHARD, T. L., VARNER, D. D., ... GILULA, N. B.
(1994).
STRUCTURAL AND FUNCTIONAL-ANALYSIS OF GAP JUNCTION EXPRESSION IN EQUINE ENDOMETRIAL EPITHELIUM. Biology of Reproduction.
98-98.
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Salinas, M. L., Fuentes, N. R., Barhoumi, R., & Chapkin, R. S.
(2017).
Dietary amphiphilic polyphenols modulate the biophysical properties of plasma membrane organization and membrane-dependent macropinocytosis. Cancer Research.
255-255.
Research
investigator on
- Texas A&M Center for Environmental Health Research awarded by National Institute of Environmental Health Sciences - (Durham, North Carolina, United States) 2019 - 2024
- Circadian Regulation of PAH Metabolism awarded by National Institute of Environmental Health Sciences - (Durham, North Carolina, United States) 2015 - 2021
Works By Students
chaired theses and dissertations
-
Hegde, Bharati Krishna (2004-09). Mathematical modelling and analysis of calcium oscillations in excitable and non-excitable cell lines.
Background
education and training
- Ph.D. in Materials Science, Claude Bernard University Lyon 1 - (Villeurbanne, France) 1984
- M.Sc. in Materials Science, Claude Bernard University Lyon 1 - (Villeurbanne, France) 1982
Contact
first name
- Roula
has last name
- Mouneimne
mailing address
-
Texas A&M University
Veterinary Integrative Biosciences
4458 TAMU
College Station, TX 77843-4458
USA
Other
- rmouneimne@tamu.edu