Stable rightward shifts of the oxyhemoglobin dissocation curve induced by encapsulation of inositol hexaphosphate in red blood cells using electroporation
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Rightward shifts of 50-100% of the P50 values in the oxygen dissociation curve of intracellular hemoglobin are obtained after encapsulation of inositol hexaphosphate in mouse and dog red blood cells (RBC) by electroporation. Life spans of mouse RBC-myo-inositol hexaphosphate in circulation are unchanged from the normal RBC values.
author list (cited authors)
Mouneimne, Y., Barhoumi, R., Myers, T., Slogoff, S., & Nicolau, C.