HR job title
- Professor
- Contact Info
- ORCiD
- 0000-0002-7435-0092
Benedik, Michael Regents Professor
Positions
- Regents Professor, Biology, College of Arts and Sciences
My laboratory studies basic biological problems using molecular genetic methods with simple microbial systems. Additionally we are developing novel microbial approaches for biotechnological applications.
- Overview
- Publications
- Teaching
- Works By Students
- Background
- Contact
- Other
- View All
Overview
Publications
selected publications
-
academic article
-
Song, S., Semenova, E., Severinov, K., Fernndez-Garca, L., Benedik, M. J., Maeda, T., & Wood, T. K.
(2022).
CRISPR-Cas Controls Cryptic Prophages. International Journal of Molecular Sciences.
23(24), 16195-16195.
-
Liu, X., Lin, S., Liu, T., Zhou, Y., Wang, W., Yao, J., ... Wang, X.
(2021).
Xenogeneic silencing relies on temperature-dependent phosphorylation of the host H-NS protein in Shewanella. Nucleic Acids Research.
49(6), 3427-3440.
-
Song, S., Kim, J., Yamasaki, R., Oh, S., Benedik, M. J., & Wood, T. K.
(2021).
Escherichia coli cryptic prophages sense nutrients to influence persister cell resuscitation. Environmental Microbiology.
23(11), 7245-7254.
-
Yamasaki, R., Song, S., Benedik, M. J., & Wood, T. K.
(2020).
Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes. iScience.
23(1), 100792-100792.
-
Benedik, M. J., & Sewell, B. T.
(2018).
Cyanide-degrading nitrilases in nature. The Journal of General and Applied Microbiology.
64(2), 90-93.
-
Park, J. M., Trevor Sewell, B., & Benedik, M. J.
(2017).
Cyanide bioremediation: the potential of engineered nitrilases. 101(8), 3029-3042.
-
Crum, M. A., Sewell, B. T., & Benedik, M. J.
(2016).
Bacillus pumilus Cyanide Dihydratase Mutants with Higher Catalytic Activity. 7(AUG), 1264.
-
Park, J. M., Ponder, C. M., Sewell, B. T., & Benedik, M. J.
(2016).
Residue Y70 of the Nitrilase Cyanide Dihydratase from Bacillus pumilus Is Critical for Formation and Activity of the Spiral Oligomer. 26(12), 2179-2183.
-
Kwan, B. W., Lord, D. M., Peti, W., Page, R., Benedik, M. J., & Wood, T. K.
(2015).
The MqsR/MqsA toxin/antitoxin system protects Escherichia coli during bile acid stress. Environmental Microbiology.
17(9), 3168-3181.
-
Crum, M., Park, J. M., Mulelu, A. E., Sewell, B. T., & Benedik, M. J.
(2015).
Probing C-terminal interactions of the Pseudomonas stutzeri cyanide-degrading CynD protein. Applied Microbiology and Biotechnology.
99(7), 3093-3102.
-
Hu, Y., Kwan, B. W., Osbourne, D. O., Benedik, M. J., & Wood, T. K.
(2015).
Toxin YafQ increases persister cell formation by reducing indole signalling. Environmental Microbiology.
17(4), 1275-1285.
-
Ilori, M. O., Picardal, F. W., Aramayo, R., Adebusoye, S. A., Obayori, O. S., & Benedik, M. J.
(2015).
Catabolic plasmid specifying polychlorinated biphenyl degradation in Cupriavidus sp. strain SK-4: mobilization and expression in a pseudomonad. Journal of Basic Microbiology: an international journal on biochemistry, physiology, genetics, morphology and ecology of microorganisms.
55(3), 338-345.
-
Kwan, B. W., Osbourne, D. O., Hu, Y., Benedik, M. J., & Wood, T. K.
(2015).
Phosphodiesterase DosP increases persistence by reducing cAMP which reduces the signal indole. Biotechnology and Bioengineering.
112(3), 588-600.
-
Crum, M. A., Park, J. M., Sewell, B. T., & Benedik, M. J.
(2015).
C-terminal hybrid mutant of Bacillus pumilus cyanide dihydratase dramatically enhances thermal stability and pH tolerance by reinforcing oligomerization. Journal of Applied Microbiology.
118(4), 881-889.
-
Vilo, C., Benedik, M. J., Ilori, M., & Dong, Q.
(2014).
Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Clorobenzoic Acid-Degrading Bacterium. Genome Announcements.
2(4), e00664-e00614.
-
Vilo, C., Benedik, M. J., Ilori, M., & Dong, Q.
(2014).
Erratum for Vilo et al., Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Chlorobenzoic Acid-Degrading Bacterium. Genome Announcements.
2(4), e00756-e00714.
-
Guo, Y., Quiroga, C., Chen, Q., McAnulty, M. J., Benedik, M. J., Wood, T. K., & Wang, X.
(2014).
RalR (a DNase) and RalA (a small RNA) form a type I toxin-antitoxin system in Escherichia coli. Nucleic Acids Research.
42(10), 6448-6462.
-
Cheng, H., Soo, V., Islam, S., McAnulty, M. J., Benedik, M. J., & Wood, T. K.
(2014).
Toxin GhoT of the GhoT/GhoS toxin/antitoxin system damages the cell membrane to reduce adenosine triphosphate and to reduce growth under stress. Environmental Microbiology.
16(6), 1741-1754.
-
Vilo, C., Benedik, M. J., Ilori, M., & Dong, Q.
(2014).
Draft Genome Sequence of Cupriavidus sp. Strain SK-4, a di-ortho-Substituted Biphenyl-Utilizing Bacterium Isolated from Polychlorinated Biphenyl-Contaminated Sludge. Genome Announcements.
2(3), e00474-e00414.
-
Vilo, C., Benedik, M. J., Ilori, M., & Dong, Q.
(2014).
Draft Genome Sequence of Cupriavidus sp. Strain SK-3, a 4-Chlorobiphenyl- and 4-Chlorobenzoic Acid-Degrading Bacterium (vol 2, e00664-14, 2014). Genome Announcements.
2(4),
-
Martnez, A. K., Gordon, E., Sengupta, A., Shirole, N., Klepacki, D., Martinez-Garriga, B., ... Cruz-Vera, L. R.
(2014).
Interactions of the TnaC nascent peptide with rRNA in the exit tunnel enable the ribosome to respond to free tryptophan. Nucleic Acids Research.
42(2), 1245-1256.
-
Wang, X., Lord, D. M., Hong, S. H., Peti, W., Benedik, M. J., Page, R., & Wood, T. K.
(2013).
Type II toxin/antitoxin MqsR/MqsA controls type V toxin/antitoxin GhoT/GhoS. Environmental Microbiology.
15(6), 1734-1744.
-
Kwan, B. W., Valenta, J. A., Benedik, M. J., & Wood, T. K.
(2013).
Arrested protein synthesis increases persister-like cell formation. Antimicrobial Agents and Chemotherapy.
57(3), 1468-1473.
-
Vilo, C. A., Benedik, M. J., Kunz, D. A., & Dong, Q.
(2012).
Draft genome sequence of the cyanide-utilizing bacterium Pseudomonas fluorescens strain NCIMB 11764. JOURNAL OF BACTERIOLOGY.
194(23), 6618-6619.
-
Hong, S. H., Wang, X., O'Connor, H. F., Benedik, M. J., & Wood, T. K.
(2012).
Bacterial persistence increases as environmental fitness decreases. Microb Biotechnol.
5(4), 509-522.
-
Hu, Y., Benedik, M. J., & Wood, T. K.
(2012).
Antitoxin DinJ influences the general stress response through transcript stabilizer CspE. Environmental Microbiology.
14(3), 669-679.
-
Martnez, A. K., Shirole, N. H., Murakami, S., Benedik, M. J., Sachs, M. S., & Cruz-Vera, L. R.
(2012).
Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function. Nucleic Acids Research.
40(5), 2247-2257.
-
Wang, X., Lord, D. M., Cheng, H., Osbourne, D. O., Hong, S. H., Sanchez-Torres, V., ... Wood, T. K.
(2012).
A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS. Nature Chemical Biology.
8(10), 855-861.
-
Wang, L., Watermeyer, J. M., Mulelu, A. E., Sewell, B. T., & Benedik, M. J.
(2012).
Engineering pH-tolerant mutants of a cyanide dihydratase. Applied Microbiology and Biotechnology.
94(1), 131-140.
-
Wang, X., Kim, Y., Hong, S. H., Ma, Q., Brown, B. L., Pu, M., ... Wood, T. K.
(2011).
Antitoxin MqsA helps mediate the bacterial general stress response. Nature Chemical Biology.
7(6), 359-366.
-
Abou-Nader, M., & Benedik, M. J.
(2010).
Rapid generation of random mutant libraries. Bioengineered.
1(5), 337-340.
-
Dvoracek, C. M., Sukhonosova, G., Benedik, M. J., & Grunlan, J. C.
(2009).
Antimicrobial behavior of polyelectrolyte-surfactant thin film assemblies. Langmuir: the ACS journal of surfaces and colloids.
25(17), 10322-10328.
-
Ju, J., Qi, J., Xu, S., Ohnishi, K., Benedik, M. J., Xue, Y., & Ma, Y.
(2009).
Crystallization and preliminary X-ray study of alkaline alanine racemase from Bacillus pseudofirmus OF4. 65(Pt 2), 166-168.
-
Thuku, R. N., Brady, D., Benedik, M. J., & Sewell, B. T.
(2009).
Microbial nitrilases: versatile, spiral forming, industrial enzymes. Journal of Applied Microbiology.
106(3), 703-727.
-
Dent, K. C., Weber, B. W., Benedik, M. J., & Sewell, B. T.
(2009).
The cyanide hydratase from Neurospora crassa forms a helix which has a dimeric repeat. Applied Microbiology and Biotechnology.
82(2), 271-278.
-
Basile, L. J., Willson, R. C., Sewell, B. T., & Benedik, M. J.
(2008).
Genome mining of cyanide-degrading nitrilases from filamentous fungi. Applied Microbiology and Biotechnology.
80(3), 427-435.
-
Woodward, J. D., Weber, B. W., Scheffer, M. P., Benedik, M. J., Hoenger, A., & Sewell, B. T.
(2008).
Helical structure of unidirectionally shadowed metal replicas of cyanide hydratase from Gloeocercospora sorghi. Journal of Structural Biology.
161(2), 111-119.
-
Strych, U., Davlieva, M., Longtin, J. P., Murphy, E. L., Im, H., Benedik, M. J., & Krause, K. L.
(2007).
Purification and preliminary crystallization of alanine racemase from Streptococcus pneumoniae. BMC Microbiology.
7(1), 40.
-
Sewell, B. T., Thuku, R. N., Zhang, X., & Benedik, M. J.
(2005).
Oligomeric structure of nitrilases: effect of mutating interfacial residues on activity. Annals of the New York Academy of Sciences.
1056(1), 153-159.
-
LeMagueres, P., Im, H., Ebalunode, J., Strych, U., Benedik, M. J., Briggs, J. M., Kohn, H., & Krause, K. L.
(2005).
The 1.9 A crystal structure of alanine racemase from Mycobacterium tuberculosis contains a conserved entryway into the active site. Biochemistry.
44(5), 1471-1481.
-
Jandhyala, D. M., Willson, R. C., Sewell, B. T., & Benedik, M. J.
(2005).
Comparison of cyanide-degrading nitrilases. Applied Microbiology and Biotechnology.
68(3), 327-335.
-
Nawarathna, D., Claycomb, J. R., Miller, J. H., & Benedik, M. J.
(2005).
Nonlinear dielectric spectroscopy of live cells using superconducting quantum interference devices. Applied Physics Letters.
86(2), 023902-023902.
-
Prodan, C., Mayo, F., Claycomb, J. R., Miller, J. H., & Benedik, M. J.
(2004).
Low-frequency, low-field dielectric spectroscopy of living cell suspensions. Journal of Applied Physics.
95(7), 3754-3756.
-
LeMagueres, P., Im, H., Dvorak, A., Strych, U., Benedik, M., & Krause, K. L.
(2003).
Crystal structure at 1.45 A resolution of alanine racemase from a pathogenic bacterium, Pseudomonas aeruginosa, contains both internal and external aldimine forms. Biochemistry.
42(50), 14752-14761.
-
Kim, M. G., Strych, U., Krause, K., Benedik, M., & Kohn, H.
(2003).
Evaluation of amino-substituted heterocyclic derivatives as alanine racemase inhibitors. MEDICINAL CHEMISTRY RESEARCH.
12(3), 130-138.
-
Jandhyala, D., Berman, M., Meyers, P. R., Sewell, B. T., Willson, R. C., & Benedik, M. J.
(2003).
CynD, the cyanide dihydratase from Bacillus pumilus: gene cloning and structural studies. Applied and Environmental Microbiology.
69(8), 4794-4805.
-
Kim, M. G., Strych, U., Krause, K., Benedik, M., & Kohn, H.
(2003).
N(2)-substituted D,L-cycloserine derivatives: synthesis and evaluation as alanine racemase inhibitors. Journal of Antibiotics: an international journal devoted to research on bioactive microbial products.
56(2), 160-168.
-
Gibbs, P. R., Riddle, R. R., Marchal, L., Benedik, M. J., & Willson, R. C.
(2003).
Purification and characterization of 2'aminobiphenyl-2,3-diol 1,2-dioxygenase from Pseudomonas sp. LD2. Protein Expression and Purification.
32(1), 35-43.
-
Riddle, R. R., Gibbs, P. R., Willson, R. C., & Benedik, M. J.
(2003).
Purification and properties of 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase involved in microbial degradation of carbazole. Protein Expression and Purification.
28(1), 182-189.
-
Sewell, B. T., Berman, M. N., Meyers, P. R., Jandhyala, D., & Benedik, M. J.
(2003).
The cyanide degrading nitrilase from Pseudomonas stutzeri AK61 is a two-fold symmetric, 14-subunit spiral. Structure.
11(11), 1413-1422.
-
Samartzidou, H., Mehrazin, M., Xu, Z., Benedik, M. J., & Delcour, A. H.
(2003).
Cadaverine inhibition of porin plays a role in cell survival at acidic pH. JOURNAL OF BACTERIOLOGY.
185(1), 13-19.
-
Riddle, R. R., Gibbs, P. R., Willson, R. C., & Benedik, M. J.
(2003).
Recombinant carbazole-degrading strains for enhanced petroleum processing. 30(1), 6-12.
-
Strych, U., & Benedik, M. J.
(2002).
Mutant analysis shows that alanine racemases from Pseudomonas aeruginosa and Escherichia coli are dimeric. JOURNAL OF BACTERIOLOGY.
184(15), 4321-4325.
-
Marty, K. B., Williams, C. L., Guynn, L. J., Benedik, M. J., & Blanke, S. R.
(2002).
Characterization of a cytotoxic factor in culture filtrates of Serratia marcescens. Infection and Immunity.
70(3), 1121-1128.
-
Berkmen, M., & Benedik, M. J.
(2002).
Multi-copy repression of Serratia marcescens nuclease expression by dinI. Current Microbiology: an international journal.
44(1), 44-48.
-
Filimonova, M. N., Gubskaya, V. P., Nuretdinov, I. A., Benedik, M. J., Cherepanova, N. A., & Leshchinskaya, I. B.
(2001).
Study of the mechanism of action of p-chloromercuribenzoate on endonuclease from the bacterium Serratia marcescens. Biokhimiya.
66(3), 399-404.
-
Strych, U., Penland, R. L., Jimenez, M., Krause, K. L., & Benedik, M. J.
(2001).
Characterization of the alanine racemases from two mycobacteria. FEMS Microbiology Letters.
196(2), 93-98.
-
Filimonova, M. N., Gubskaya, V. P., Nuretdinov, I. A., Benedik, M. J., Cherepanova, N. A., & Leshchinskaya, I. B.
(2001).
Study of the mechanism of action of p-chloromercuribenzoate on endonuclease from the bacterium Serratia marcescens. Biochemistry (Moscow).
66(3), 323-327.
-
Gibbs, P. R., Riddle, R. R., Benedik, M. J., & Willson, R. C.
(2000).
Microbial denitrogenation of fossil fuels. ACS National Meeting Book of Abstracts.
219, U167-U167.
-
Strych, U., Dai, W., & Benedik, M. J.
(1999).
The NucE and NucD lysis proteins are not essential for secretion of the Serratia marcescens extracellular nuclease. Microbiology.
145 ( Pt 5)(5), 1209-1216.
-
Dang, V. D., Benedik, M. J., Ekwall, K., Choi, J., Allshire, R. C., & Levin, H. L.
(1999).
A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast. Molecular and Cellular Biology.
19(3), 2351-2365.
-
Balasundaram, D., Benedik, M. J., Morphew, M., Dang, V. D., & Levin, H. L.
(1999).
Nup124p is a nuclear pore factor of Schizosaccharomyces pombe that is important for nuclear import and activity of retrotransposon Tf1. Molecular and Cellular Biology.
19(8), 5768-5784.
-
Riddle, R. R., Willson, R. C., & Benedik, M. J.
(1999).
Temperature- and solvent-tolerant mutants of filamentous bacteriophage helper M13 KO7. 21(1), 87-90.
-
Samartzidou, H., Xu, Z., Benedik, M. J., & Delcour, A. H.
(1999).
Mutational analysis of porin inhibition by polyamines. Biophysical Journal.
76(1), A138-A138.
-
Filimonova, M. N., Benedik, M. J., Urazov, N. G., & Leshchinskaia, I. B.
(1999).
[Polydispersity of Serratia marcescens nuclease at optimal pH values]. 35(1), 20-24.
-
Balasundaram, D., Benedik, M., & Levin, H. L.
(1998).
The retrotransposon Tf1 possesses a specific pathway of nuclear import. Molecular Biology of the Cell.
9, 187A-187A.
-
Gibbs, P. R., Riddle, R. R., Benedik, M. J., & Willson, R. C.
(1998).
Biochemistry of carbazole degradation. ACS National Meeting Book of Abstracts.
216, U253-U253.
-
Benedik, M. J., & Strych, U.
(1998).
Serratia marcescens and its extracellular nuclease. FEMS Microbiology Letters.
165(1), 1-13.
-
Guynn, L. J., Dai, W., & Benedik, M. J.
(1998).
Nuclease overexpression mutants of Serratia marcescens. JOURNAL OF BACTERIOLOGY.
180(8), 2262-2264.
-
Benedik, M. J., Gibbs, P. R., Riddle, R. R., & Willson, R. C.
(1998).
Microbial denitrogenation of fossil fuels. Trends in Biotechnology.
16(9), 390-395.
-
Berkmen, M., Benedik, M. J., & Blsi, U.
(1997).
The Serratia marcescens NucE protein functions as a holin in Escherichia coli. JOURNAL OF BACTERIOLOGY.
179(20), 6522-6524.
-
Filimonova, M. N., Gubskaya, V. P., Nuretdinov, I. A., Benedik, M. J., Bogomolnaya, L. M., Andreeva, M. A., & Leshchinskaya, I. B.
(1997).
Isoforms of Serratia marcescens nuclease. The role of Mg2+ in the hydrolysis mechanism. Biochemistry (Moscow).
62(9), 983-988.
-
Suh, Y., & Benedik, M. J.
(1997).
Secretion of nuclease across the outer membrane of Serratia marcescens and its energy requirements. JOURNAL OF BACTERIOLOGY.
179(3), 677-683.
-
Liu, N., Benedik, M. J., & Delcour, A. H.
(1997).
Disruption of polyamine modulation by a single amino acid substitution on the L3 loop of the OmpC porin channel. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.
1326(2), 201-212.
-
Gibbs, P. R., Riddle, R., Benedik, M. J., & Willson, R. C.
(1996).
Microbial denitrogenation of fossil fuels. ACS National Meeting Book of Abstracts.
212, 3-PETR.
-
Suh, Y., Jin, S., Ball, T. K., & Benedik, M. J.
(1996).
Two-step secretion of the Serratia marcescens extracellular nuclease. JOURNAL OF BACTERIOLOGY.
178(13), 3771-3778.
-
Liu, N. Z., Benedik, M. J., & Delcour, A. H.
(1996).
Effects of mutations at two neighboring aspartate residues in the L3 loop of E-coli OmpC porin. Biophysical Journal.
70(2), TU519-TU519.
-
Chen, Y. C., Suh, Y., Riise, E., Kartman, B., Jin, S., & Benedik, M. J.
(1996).
Inhibition of Serratia marcescens nuclease secretion by a truncated nuclease peptide. Gene.
172(1), 9-16.
-
Maillard, K. I., Benedik, M. J., & Willson, R. C.
(1996).
Rapid detection of mutagens by induction of luciferase bearing prophage in Escherichia coli. Environmental Science and Technology (Washington).
30(8), 2478-2483.
-
Jin, S., Chen, Y., Christie, G. E., & Benedik, M. J.
(1996).
Regulation of the Serratia marcescens extracellular nuclease: positive control by a homolog of P2 Ogr encoded by a cryptic prophage. 256(2), 264-278.
-
Suh, Y., Alpaugh, M., Krause, K. L., & Benedik, M. J.
(1995).
Differential secretion of isoforms of Serratia marcescens extracellular nuclease. Applied and Environmental Microbiology.
61(11), 4083-4088.
-
FILIMONOVA, M. N., & BENEDIK, M. J.
(1995).
NUCLEASE OF SERRATIA-MARCESCENS - ENZYME-SUBSTRATE RATIO FOR MANIFESTING MAXIMAL ACTIVITY. Biochemistry (Moscow).
60(9), 1143-1144.
-
Li, X., Tetling, S., Winkler, U. K., Jaeger, K. E., & Benedik, M. J.
(1995).
Gene cloning, sequence analysis, purification, and secretion by Escherichia coli of an extracellular lipase from Serratia marcescens. Applied and Environmental Microbiology.
61(7), 2674-2680.
-
BENEDIK, M., DJOJONEGORO, B., & WILLSON, R.
(1995).
USE OF PHAGE SURFACE DISPLAY FOR PROTEIN ENGINEERING OF FUNCTIONAL PROTEINS. Journal of Cellular Biochemistry.
46-46.
-
Givskov, M., Eberl, L., Christiansen, G., Benedik, M. J., & Molin, S.
(1995).
Induction of phospholipase- and flagellar synthesis in Serratia liquefaciens is controlled by expression of the flagellar master operon flhD. Molecular Microbiology.
15(3), 445-454.
-
Filimonova, M. N., Krause, K. L., & Benedik, M. J.
(1994).
Kinetic studies of the Serratia marcescens extracellular nuclease isoforms. Biochem Mol Biol Int.
33(6), 1229-1236.
-
Miller, M. D., Tanner, J., Alpaugh, M., Benedik, M. J., & Krause, K. L.
(1994).
2.1 A structure of Serratia endonuclease suggests a mechanism for binding to double-stranded DNA. 1(7), 461-468.
-
Jin, S., & Benedik, M. J.
(1994).
Sequences of the Serratia marcescens rplS and trmD genes. Gene.
145(1), 147-148.
-
WILLSON, R. C., DJOJONEGORO, B., & BENEDIK, M. J.
(1993).
BACTERIOPHAGE SURFACE DISPLAY OF PROTEIN-A FOR ISOLATION OF BINDING VARIANTS. The FASEB Journal.
7(7), A1307-A1307.
-
WILLSON, R. C., DJOJONEGORO, B., & BENEDIK, M.
(1993).
PHAGE DISPLAY OF PROTEIN-A FOR ISOLATION OF NOVEL FORMS. ACS National Meeting Book of Abstracts.
205, 65-BTEC.
-
Ball, T. K., Suh, Y., & Benedik, M. J.
(1992).
Disulfide bonds are required for Serratia marcescens nuclease activity. Nucleic Acids Research.
20(19), 4971-4974.
-
Suh, Y., & Benedik, M. J.
(1992).
Production of active Serratia marcescens metalloprotease from Escherichia coli by alpha-hemolysin HlyB and HlyD. JOURNAL OF BACTERIOLOGY.
174(7), 2361-2366.
-
Chen, Y. C., Shipley, G. L., Ball, T. K., & Benedik, M. J.
(1992).
Regulatory mutants and transcriptional control of the Serratia marcescens extracellular nuclease gene. Molecular Microbiology.
6(5), 643-651.
-
Miller, M. D., Benedik, M. J., Sullivan, M. C., Shipley, N. S., & Krause, K. L.
(1991).
Crystallization and preliminary crystallographic analysis of a novel nuclease from Serratia marcescens. JOURNAL OF MOLECULAR BIOLOGY.
222(1), 27-30.
-
Braunagel, S. C., & Benedik, M. J.
(1990).
The metalloprotease gene of Serratia marcescens strain SM6. 222(2-3), 446-451.
-
Ball, T. K., Wasmuth, C. R., Braunagel, S. C., & Benedik, M. J.
(1990).
Expression of Serratia marcescens extracellular proteins requires recA. JOURNAL OF BACTERIOLOGY.
172(1), 342-349.
-
Benedik, M. J.
(1989).
High efficiency transduction of single strand plasmid DNA into enteric bacteria. 218(2), 353-354.
-
Hines, D. A., Saurugger, P. N., Ihler, G. M., & Benedik, M. J.
(1988).
Genetic analysis of extracellular proteins of Serratia marcescens. JOURNAL OF BACTERIOLOGY.
170(9), 4141-4146.
-
PAOLI, G. C., BENEDIK, M., MEYER, E., & LUEKING, D. R.
(1988).
RECOVERY OF THE GLYCEROL AUXOTROPHY OF ESCHERICHIA-COLI STRAIN BB26-36 (PLSB) BY CLONED RHODOBACTER SPHAEROIDES DNA FRAGMENT. The FASEB Journal.
2(5), A1333-A1333.
-
McLaughlin, G. L., Benedik, M. J., & Campbell, G. H.
(1987).
Repeated immunogenic amino acid sequences of Plasmodium species share sequence homologies with proteins from humans and human viruses. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE.
37(2), 258-262.
-
Ball, T. K., Saurugger, P. N., & Benedik, M. J.
(1987).
The extracellular nuclease gene of Serratia marcescens and its secretion from Escherichia coli. Gene.
57(2-3), 183-192.
-
Zurawski, G., Benedik, M., Kamb, B. J., Abrams, J. S., Zurawski, S. M., & Lee, F. D.
(1986).
Activation of mouse T-helper cells induces abundant preproenkephalin mRNA synthesis. Science.
232(4751), 772-775.
-
Zurawski, S. M., Mosmann, T. R., Benedik, M., & Zurawski, G.
(1986).
Alterations in the amino-terminal third of mouse interleukin 2: effects on biological activity and immunoreactivity. JOURNAL OF IMMUNOLOGY.
137(10), 3354-3360.
-
Taylor, A., Benedik, M., & Campbell, A.
(1983).
Location of the Rz gene in bacteriophage lambda. 26(2-3), 159-163.
-
Mascarenhas, D., Trueheart, J., Benedik, M., & Campbell, A.
(1983).
Retroregulation: control of integrase expression by the b2 region of bacteriophages lambda and 434. Virology.
124(1), 100-108.
-
Benedik, M., Mascarenhas, D., & Campbell, A.
(1983).
The integrase promoter and T'I terminator in bacteriophages lambda and 434. Virology.
126(2), 658-668.
-
Benedik, M., Mascarenhas, D., & Campbell, A.
(1982).
Probing cII and himA action at the integrase promoter pi of bacteriophage lambda. Gene.
19(3), 303-311.
-
Miller, H. I., Abraham, J., Benedik, M., Campbell, A., Court, D., Echols, H., ... Sosa, L.
(1981).
Regulation of the integration-excision reaction by bacteriophage lambda. Cold Spring Harbor Laboratory: Symposia on Quantitative Biology.
45 Pt 1(0), 439-445.
-
Abraham, J., Mascarenhas, D., Fischer, R., Benedik, M., Campbell, A., & Echols, H.
(1980).
DNA sequence of regulatory region for integration gene of bacteriophage lambda. Proceedings of the National Academy of Sciences of USA.
77(5), 2477-2481.
-
Heffernan, L., Benedik, M., & Campbell, A.
(1979).
Regulatory structure of the insertion region of bacteriophage lambda. Cold Spring Harbor Laboratory: Symposia on Quantitative Biology.
43 Pt 2(0), 1127-1134.
-
Benedik, M., Fennewald, M., & Shapiro, J.
(1977).
Transposition of a beta-lactamase locus from RP1 into Pseudomonas putida degradative plasmids. JOURNAL OF BACTERIOLOGY.
129(2), 809-814.
-
Song, S., Semenova, E., Severinov, K., Fernndez-Garca, L., Benedik, M. J., Maeda, T., & Wood, T. K.
(2022).
CRISPR-Cas Controls Cryptic Prophages. International Journal of Molecular Sciences.
23(24), 16195-16195.
-
conference paper
-
Krause, K., Benedik, M., Briggs, J., & Kohn, H.
(2004).
Alanine racemase as a template for TB drug design. Protein Science.
65-65.
-
Gibbs, P. R., Riddle, R. R., Benedik, M. J., & Willson, R. C.
(1997).
Microbial degradation of carbazole. ACS National Meeting Book of Abstracts.
230-BIOT.
-
Krause, K., Benedik, M., Briggs, J., & Kohn, H.
(2004).
Alanine racemase as a template for TB drug design. Protein Science.
65-65.
Teaching
teaching activities
- BIOL489 Sptp: Synthetic Microbiology Instructor
Works By Students
chaired theses and dissertations
-
Abou Nader, Mary 1983- (2012-12). Directed Evolution of Cyanide Degrading Enzymes.
-
Ball, Timothy Keith (1990-05). Regulation of expression and excretion of a Serratia marcescens nuclease.
-
Basile, Lacy Jamel (2008-08). Cyanide-degrading enzymes for bioremediation.
-
Charles, Tysheena Perkins (2008-12). Unraveling the phenotype of colicin cytoplasmic import (cim) mutants.
-
Kumar, Krithika (2011-12). Regulation of the Nitrogen Fixation Genes in the Heterocystous Cyanobacterium Anabaena sp. Strain PCC 7120.
-
Mella Herrera, Rodrigo Andres (2010-08). Heterocyst Morphogenesis and Gene Expression in Anabaena sp. PCC 7120.
-
Park, Jason M (2014-08). Regions Involved in the Oligomerization and Activity of the Spiral Forming Nitrilase Cyanide Dihydratase.
-
Towers, Leah Nicole (2010-12). The Mystery of the Chaetognatha: A Molecular Phylogenetic Approach Using Pelagic Chaetognath Species on Pelican Island, Galveston, Texas.
-
Wang, Lan (2008-05). Engineering pH tolerant mutants of a cyanide dihydratase of Bacillus pumilus C1 and identifying constraints on substrate specificity in nitrilases.
Background
education and training
- Ph.D. in Biology - Molecular Genetics, Stanford University - (Stanford, California, United States) 1982
- A.B. in Biology, University of Chicago - (Chicago, Illinois, United States) 1976
awards and honors
Contact
first name
- Michael
has last name
- Benedik
mailing address
-
Texas A&M University
Provost And Exec Vice President
1248 TAMU
College Station, TX 77843-1248
USA
Other
In the News
- Celebrating MLK's Dream News Release
- Texas A&M Hosts Conference To Advance International Education News Release
- Texas A&M Leadership To The Aggie Community: 'Be An Ally' News Release
- benedik@tamu.edu