HR job title
- Professor
- Contact Info
- 1 214 828 8292
- Websites
- ORCiD
- 0000-0002-2906-9074
Qin, Chunlin Professor and Associate Department Head
Positions
- Professor and Associate Department Head, Biomedical Sciences, School of Dentistry
- Overview
- Publications
- Research
- Teaching
- Works By Students
- Background
- Contact
- Other
- View All
Overview
Publications
selected publications
-
academic article
-
Huang, Y., Chen, H., Zhang, H., Lu, Y., & Qin, C.
(2022).
FAM20C plays a critical role in the development of mouse vertebra. The Spine Journal.
22(2), 337-348.
-
Jani, P., Zhang, H., Benson, M. D., & Qin, C.
(2020).
Noggin inhibition of mouse dentinogenesis. Journal of Oral Biosciences.
62(1), 72-79.
-
Liang, T., Zhang, H., Xu, Q., Wang, S., Qin, C., & Lu, Y.
(2019).
Mutant Dentin Sialophosphoprotein Causes Dentinogenesis Imperfecta. Journal of Dental Research.
98(8), 912-919.
-
Saiyin, W., Li, L., Zhang, H., Lu, Y., & Qin, C.
(2019).
Inactivation of FAM20B causes cell fate changes in annulus fibrosus of mouse intervertebral disc and disc defects via the alterations of TGF- and MAPK signaling pathways. BBA: Molecular Basis of Disease.
1865(12), 165555-165555.
-
Miao, N., Zhan, Y., Xu, Y., Yuan, H., Qin, C., Lin, F., ... Zhang, B.
(2019).
Loss of Fam20c causes defects in the acinar and duct structure of salivary glands in mice. International Journal of Molecular Medicine.
43(5), 2103-2117.
-
Liu, X., Li, N., Zhang, H., Liu, J., Zhou, N., Ran, C., ... Liu, C.
(2018).
Inactivation of Fam20b in the neural crest-derived mesenchyme of mouse causes multiple craniofacial defects. European Journal Of Oral Sciences.
126(5), 433-436.
-
Liu, C., Zhang, H., Jani, P., Wang, X., Lu, Y., Li, N., Xiao, J., & Qin, C.
(2018).
FAM20C regulates osteoblast behaviors and intracellular signaling pathways in a cell-autonomous manner. Journal of Cellular Physiology.
233(4), 3476-3486.
-
Liu, C., Zhou, N., Wang, Y. u., Zhang, H., Jani, P., Wang, X., ... Qin, C.
(2018).
Abrogation of Fam20c altered cell behaviors and BMP signaling of immortalized dental mesenchymal cells. Experimental Cell Research.
363(2), 188-195.
-
Jiang, C., Zurick, K., Qin, C., & Bernards, M. T.
(2018).
Probing the influence of SIBLING proteins on collagen-I fibrillogenesis and denaturation. Connective Tissue Research.
59(3), 274-286.
-
Jani, P., Liu, C., Zhang, H., Younes, K., Benson, M. D., & Qin, C.
(2018).
The role of bone morphogenetic proteins 2 and 4 in mouse dentinogenesis. Archives of Oral Biology.
90, 33-39.
-
Zhang, H., Xie, X., Liu, P., Liang, T., Lu, Y., & Qin, C.
(2018).
Transgenic expression of dentin phosphoprotein (DPP) partially rescued the dentin defects of DSPP-null mice. PLoS ONE.
13(4), e0195854-e0195854.
-
Yan, W., Ma, P., Tian, Y. e., Wang, J., Qin, C., Feng, J. Q., & Wang, X.
(2017).
The importance of a potential phosphorylation site in enamelin on enamel formation. International Journal of Oral Science.
9(11), e4-6.
-
Arnold, P., Koopmann, L., Peters, F., Birkenfeld, F., Goff, S., Damm, T., ... Becker-Pauly, C.
(2017).
Deficiency of the DSPP-cleaving enzymes meprin and meprin does not result in dentin malformation in mice. Cell and Tissue Research.
367(2), 351-358.
-
Zhang, H., Jani, P., Liang, T., Lu, Y., & Qin, C.
(2017).
Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice. Journal of Molecular Histology.
48(2), 83-98.
-
Liu, P., Ma, S. u., Zhang, H., Liu, C., Lu, Y., Chen, L. i., & Qin, C.
(2017).
Specific ablation of mouse Fam20C in cells expressing type I collagen leads to skeletal defects and hypophosphatemia. Scientific Reports.
7(1), 3590.
-
Ma, S., Liu, W., Liu, P., Liu, J., Chen, L., & Qin, C.
(2016).
Tanshinone IIA treatment alleviated the rat gingival connective tissue overgrowth induced by cyclosporine A. Journal of Periodontal Research.
51(5), 567-576.
-
Ma, P., Yan, W., Tian, Y. e., Wang, J., Feng, J. Q., Qin, C., Cheng, Y., & Wang, X.
(2016).
Inactivation of Fam20B in Joint Cartilage Leads to Chondrosarcoma and Postnatal Ossification Defects. Scientific Reports.
6(1), 29814.
-
Liang, T., Meng, T., Wang, S., Qin, C., & Lu, Y.
(2016).
The LPV Motif Is Essential for the Efficient Export of Secretory DMP1 From the Endoplasmic Reticulum. Journal of Cellular Physiology.
231(7), 1468-1475.
-
Xie, X., Liu, C., Zhang, H., Jani, P. H., Lu, Y., Wang, X., Zhang, B., & Qin, C.
(2016).
Abrogation of epithelial BMP2 and BMP4 causes Amelogenesis Imperfecta by reducing MMP20 and KLK4 expression. Scientific Reports.
6(1), 25364.
-
Verdelis, K., Szabo-Rogers, H. L., Xu, Y., Chong, R., Kang, R., Cusack, B. J., ... Beniash, E.
(2016).
Accelerated enamel mineralization in Dspp mutant mice. 52-54, 246-259.
-
Jani, P. H., Gibson, M. P., Liu, C., Zhang, H., Wang, X., Lu, Y., & Qin, C.
(2016).
Transgenic expression of Dspp partially rescued the long bone defects of Dmp1-null mice. Matrix Biology.
52-54, 95-112.
-
Zhang, H., Liu, P., Wang, S., Liu, C., Jani, P., Lu, Y., & Qin, C.
(2016).
Transgenic expression of dentin phosphoprotein inhibits skeletal development. European Journal of Histochemistry.
60(1), 2587-54.
-
Li, L., Liu, P., Xie, X., Ma, S. u., Liu, C., Chen, L. i., & Qin, C.
(2016).
Loss of epithelial FAM20A in mice causes amelogenesis imperfecta, tooth eruption delay and gingival overgrowth. International Journal of Oral Science.
8(2), 98-109.
-
Nurrohman, H., Saeki, K., Carneiro, K., Chien, Y. C., Djomehri, S., Ho, S. P., ... Habelitz, S.
(2016).
Repair of dentin defects from DSPP knockout mice by PILP mineralization. Journal of Materials Research.
31(3), 321-327.
-
Meng, T., Huang, Y., Wang, S., Zhang, H., Dechow, P. C., Wang, X., ... Lu, Y.
(2015).
Twist1 Is Essential for Tooth Morphogenesis and Odontoblast Differentiation. Journal of Biological Chemistry.
290(49), 29593-29602.
-
Tian, Y. e., Ma, P., Liu, C., Yang, X., Crawford, D. M., Yan, W., ... Wang, X.
(2015).
Inactivation of Fam20B in the dental epithelium of mice leads to supernumerary incisors. European Journal Of Oral Sciences.
123(6), 396-402.
-
Liu, C., Wang, X., Zhang, H., Xie, X., Liu, P., Liu, Y., ... Qin, C.
(2015).
Immortalized Mouse Floxed Fam20c Dental Papillar Mesenchymal and Osteoblast Cell Lines Retain Their Primary Characteristics. Journal of Cellular Physiology.
230(11), 2581-2587.
-
Fujikawa, K., Yokohama-Tamaki, T., Morita, T., Baba, O., Qin, C., & Shibata, S.
(2015).
An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage. European Journal of Histochemistry.
59(3), 2553-227.
-
Wu, W., Gu, S., Sun, C., He, W., Xie, X., Li, X., ... Liu, C.
(2015).
Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves. PLoS ONE.
10(9), e0136951-e0136951.
-
Feng, J. Q., Zhang, H., & Qin, C.
(2015).
Letter to the Editor, "Osterix Regulates Tooth Root Formation in a Site-specific Manner". Journal of Dental Research.
94(9), 1326-1326.
-
Mobley, C. G., Kuzynski, M., Zhang, H., Jani, P., Qin, C., & Napierala, D.
(2015).
Dspp-independent Effects of Transgenic Trps1 Overexpression on Dentin Formation. Journal of Dental Research.
94(8), 1128-1134.
-
Ren, Y., Han, X., Ho, S. P., Harris, S. E., Cao, Z., Economides, A. N., ... Feng, J. Q.
(2015).
Removal of SOST or blocking its product sclerostin rescues defects in the periodontitis mouse model. The FASEB Journal.
29(7), 2702-2711.
-
Du, E., Wang, X., Yang, W., Kaback, D., Yee, S., Qin, C., George, A., & Hao, J.
(2015).
Characterization of Fam20C expression in odontogenesis and osteogenesis using transgenic mice. International Journal of Oral Science.
7(2), 89-94.
-
Zhang, H., Jiang, Y., Qin, C., Liu, Y., Ho, S. P., & Feng, J. Q.
(2015).
Essential role of osterix for tooth root but not crown dentin formation. Journal of Bone and Mineral Research.
30(4), 742-746.
-
Wang, X., Wang, J., Liu, Y., Yuan, B., Ruest, L. B., Feng, J. Q., & Qin, C.
(2015).
The specific role of FAM20C in dentinogenesis. Journal of Dental Research.
94(2), 330-336.
-
Liu, P., Zhang, H., Liu, C., Wang, X., Chen, L. i., & Qin, C.
(2014).
Inactivation of Fam20C in cells expressing type I collagen causes periodontal disease in mice. PLoS ONE.
9(12), e114396-e114396.
-
Gibson, M. P., Jani, P., Wang, X., Lu, Y., & Qin, C.
(2014).
Overexpressing the NH2-terminal fragment of dentin sialophosphoprotein (DSPP) aggravates the periodontal defects in Dspp knockout mice. Journal of Oral Biosciences.
56(4), 143-148.
-
Lin, S., Zhang, Q. i., Cao, Z., Lu, Y., Zhang, H., Yan, K., ... Feng, J. Q.
(2014).
Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype. Journal of Biological Chemistry.
289(31), 21533-21543.
-
Ma, S. u., Liu, P., Li, Y., Hou, L., Chen, L. i., & Qin, C.
(2014).
Cyclosporine a inhibits apoptosis of rat gingival epithelium. JOURNAL OF PERIODONTOLOGY.
85(8), 1126-1134.
-
Xie, X., Ma, S. u., Li, C., Liu, P., Wang, H., Chen, L. i., & Qin, C.
(2014).
Expression of Small Integrin-Binding LIgand N-linked Glycoproteins (SIBLINGs) in the reparative dentin of rat molars. Dental Traumatology.
30(4), 285-295.
-
Wang, X., Wang, J., Yuan, B., Lu, Y., Feng, J. Q., & Qin, C.
(2014).
Overexpression of Dmp1 fails to rescue the bone and dentin defects in Fam20C knockout mice. Connective Tissue Research.
55(4), 299-303.
-
Huang, Y., Meng, T., Wang, S., Zhang, H., Mues, G., Qin, C., ... Lu, Y.
(2014).
Twist1- and Twist2-haploinsufficiency results in reduced bone formation. PLoS ONE.
9(6), e99331-e99331.
-
Gibson, M. P., Jani, P., Liu, Y., Wang, X., Lu, Y., Feng, J. Q., & Qin, C.
(2013).
Failure to process dentin sialophosphoprotein into fragments leads to periodontal defects in mice. European Journal Of Oral Sciences.
121(6), 545-550.
-
Wang, X., Jung, J., Liu, Y., Yuan, B., Lu, Y., Feng, J. Q., & Qin, C.
(2013).
The specific role of FAM20C in amelogenesis. Journal of Dental Research.
92(11), 995-999.
-
Liu, Q., Gibson, M. P., Sun, H., & Qin, C.
(2013).
Dentin sialophosphoprotein (DSPP) plays an essential role in the postnatal development and maintenance of mouse mandibular condylar cartilage. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology.
61(10), 749-758.
-
Sun, Y., Jiang, Y., Liu, Q., Gao, T., Feng, J. Q., Dechow, P., ... Liu, X.
(2013).
Biomimetic engineering of nanofibrous gelatin scaffolds with noncollagenous proteins for enhanced bone regeneration. Tissue Engineering Part A.
19(15-16), 1754-1763.
-
Zurick, K. M., Qin, C., & Bernards, M. T.
(2013).
Mineralization induction effects of osteopontin, bone sialoprotein, and dentin phosphoprotein on a biomimetic collagen substrate. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A.
101(6), 1571-1581.
-
Zhao, H., Ma, S. u., Chen, L. i., Liu, P., Xu, J., Hou, L., Chen, R., & Qin, C.
(2013).
[The effects of nicotine on bone calcium and phosphorus content and alkaline phosphatase activity in different part of rat]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology.
31(3), 225-231.
-
Li, C., Xie, X., Wang, X., Sun, Y., Liu, P., Chen, L. i., & Qin, C.
(2013).
Differential expression and localization of dentin matrix protein 1 (DMP1) fragments in mouse submandibular glands. Journal of Molecular Histology.
44(2), 231-239.
-
Gibson, M. P., Zhu, Q., Liu, Q., D'Souza, R. N., Feng, J. Q., & Qin, C.
(2013).
Loss of dentin sialophosphoprotein leads to periodontal diseases in mice. Journal of Periodontal Research.
48(2), 221-227.
-
Gibson, M. P., Liu, Q., Zhu, Q., Lu, Y., Jani, P., Wang, X., ... Qin, C.
(2013).
Role of the NH2 -terminal fragment of dentin sialophosphoprotein in dentinogenesis. European Journal Of Oral Sciences.
121(2), 76-85.
-
Gibson, M. P., Zhu, Q., Wang, S., Liu, Q., Liu, Y., Wang, X., ... Lu, Y.
(2013).
The rescue of dentin matrix protein 1 (DMP1)-deficient tooth defects by the transgenic expression of dentin sialophosphoprotein (DSPP) indicates that DSPP is a downstream effector molecule of DMP1 in dentinogenesis. Journal of Biological Chemistry.
288(10), 7204-7214.
-
Shibata, S., Sakamoto, Y., Baba, O., Qin, C., Murakami, G., & Cho, B. H.
(2013).
An immunohistochemical study of matrix proteins in the craniofacial cartilage in midterm human fetuses. European Journal of Histochemistry.
57(4), e39-270.
-
Shibata, S., Sakamoto, Y., Baba, O., Qin, C., Murakami, G., & Cho, B. H.
(2013).
An immunohistochemical study of matrix proteins in the craniofacial cartilage in midterm human fetuses. European journal of histochemistry : EJH.
57(4),
-
Wang, X., Wang, S., Lu, Y., Gibson, M. P., Liu, Y., Yuan, B., Feng, J. Q., & Qin, C.
(2012).
FAM20C plays an essential role in the formation of murine teeth. Journal of Biological Chemistry.
287(43), 35934-35942.
-
Zurick, K. M., Qin, C., & Bernards, M. T.
(2012).
Adhesion of MC3T3-E1 cells bound to dentin phosphoprotein specifically bound to collagen type I. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A.
100(9), 2492-2498.
-
Zhu, Q., Gibson, M. P., Liu, Q., Liu, Y., Lu, Y., Wang, X., Feng, J. Q., & Qin, C.
(2012).
Proteolytic processing of dentin sialophosphoprotein (DSPP) is essential to dentinogenesis. Journal of Biological Chemistry.
287(36), 30426-30435.
-
Zhu, Q., Prasad, M., Kong, H., Lu, Y., Sun, Y., Wang, X., ... Qin, C.
(2012).
Partial Blocking of Mouse DSPP Processing by Substitution of Gly451–Asp452 Bond Suggests the Presence of Secondary Cleavage Site(s). Connective Tissue Research.
53(4), 307-312.
-
Rangiani, A., Cao, Z., Sun, Y., Lu, Y., Gao, T., Yuan, B., ... Feng, J. Q.
(2012).
Protective roles of DMP1 in high phosphate homeostasis. PLoS ONE.
7(8), e42329-e42329.
-
Napierala, D., Sun, Y., Maciejewska, I., Bertin, T. K., Dawson, B., D'Souza, R., Qin, C., & Lee, B.
(2012).
Transcriptional repression of the Dspp gene leads to dentinogenesis imperfecta phenotype in Col1a1-Trps1 transgenic mice. Journal of Bone and Mineral Research.
27(8), 1735-1745.
-
Wang, X., Wang, S., Li, C., Gao, T., Liu, Y., Rangiani, A., ... Qin, C.
(2012).
Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. 8(5), e1002708-e1002708.
-
Rangiani, A., Cao, Z., Liu, Y., Voisey Rodgers, A., Jiang, Y., Qin, C., & Feng, J.
(2012).
Dentin matrix protein 1 and phosphate homeostasis are critical for postnatal pulp, dentin and enamel formation. International Journal of Oral Science.
4(4), 189-195.
-
Qin, Q., Xu, Y., He, T., Qin, C., & Xu, J.
(2012).
Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms. Cell Research.
22(1), 90-106.
-
Siyam, A., Wang, S., Qin, C., Mues, G., Stevens, R., D'Souza, R. N., & Lu, Y.
(2012).
Nuclear localization of DMP1 proteins suggests a role in intracellular signaling. Biochemical and Biophysical Research Communications.
424(3), 641-646.
-
Prasad, M., Zhu, Q., Sun, Y., Wang, X., Kulkarni, A., Boskey, A., Feng, J. Q., & Qin, C.
(2011).
Expression of dentin sialophosphoprotein in non-mineralized tissues. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology.
59(11), 1009-1021.
-
Sun, Y., Chen, L. i., Ma, S. u., Zhou, J., Zhang, H., Feng, J. Q., & Qin, C.
(2011).
Roles of DMP1 processing in osteogenesis, dentinogenesis and chondrogenesis. Cells, Tissues, Organs: in vivo, in vitro.
194(2-4), 199-204.
-
Sun, Y., Lu, Y., Chen, L., Gao, T., D'Souza, R., Feng, J. Q., & Qin, C.
(2011).
DMP1 processing is essential to dentin and jaw formation. Journal of Dental Research.
90(5), 619-624.
-
Zhang, R., Lu, Y., Ye, L., Yuan, B., Yu, S., Qin, C., ... Feng, J. Q.
(2011).
Unique roles of phosphorus in endochondral bone formation and osteocyte maturation. Journal of Bone and Mineral Research.
26(5), 1047-1056.
-
Ma, D., Zhang, R., Sun, Y., Rios, H. F., Haruyama, N., Han, X., ... Feng, J. Q.
(2011).
A novel role of periostin in postnatal tooth formation and mineralization. Journal of Biological Chemistry.
286(6), 4302-4309.
-
Lu, Y., Yuan, B., Qin, C., Cao, Z., Xie, Y., Dallas, S. L., ... Feng, J. Q.
(2011).
The biological function of DMP-1 in osteocyte maturation is mediated by its 57-kDa C-terminal fragment. Journal of Bone and Mineral Research.
26(2), 331-340.
-
Shi, J., Song, T., Jiao, X., Qin, C., & Zhou, J.
(2011).
Single-nucleotide polymorphisms (SNPs) of the IRF6 and TFAP2A in non-syndromic cleft lip with or without cleft palate (NSCLP) in a northern Chinese population. Biochemical and Biophysical Research Communications.
410(4), 732-736.
-
Sun, Y., Ma, S. u., Zhou, J., Yamoah, A. K., Feng, J. Q., Hinton, R. J., & Qin, C.
(2010).
Distribution of small integrin-binding ligand, N-linked glycoproteins (SIBLING) in the articular cartilage of the rat femoral head. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology.
58(11), 1033-1043.
-
Wang, X., Hao, J., Xie, Y., Sun, Y., Hernandez, B., Yamoah, A. K., ... Qin, C.
(2010).
Expression of FAM20C in the osteogenesis and odontogenesis of mouse. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology.
58(11), 957-967.
-
Sun, Y., Prasad, M., Gao, T., Wang, X., Zhu, Q., D'Souza, R., Feng, J. Q., & Qin, C.
(2010).
Failure to process dentin matrix protein 1 (DMP1) into fragments leads to its loss of function in osteogenesis. Journal of Biological Chemistry.
285(41), 31713-31722.
-
Jiang, B., Cao, Z., Lu, Y., Janik, C., Lauziere, S., Xie, Y., ... Feng, J. Q.
(2010).
DMP1 C-terminal mutant mice recapture the human ARHR tooth phenotype. Journal of Bone and Mineral Research.
25(10), 2155-2164.
-
Lv, K., Huang, H., Lu, Y., Qin, C., Li, Z., & Feng, J. Q.
(2010).
Circling behavior developed in Dmp1 null mice is due to bone defects in the vestibular apparatus. International Journal of Biological Sciences.
6(6), 537-545.
-
Shi, J., Jiao, X., Song, T., Zhang, B., Qin, C., & Cao, F.
(2010).
CRISPLD2 polymorphisms are associated with non-syndromic cleft lip with or without cleft palate in a northern Chinese population. European Journal Of Oral Sciences.
118(4), 430-433.
-
Zhu, Q., Sun, Y., Prasad, M., Wang, X., Yamoah, A. K., Li, Y., Feng, J., & Qin, C.
(2010).
Glycosaminoglycan chain of dentin sialoprotein proteoglycan. Journal of Dental Research.
89(8), 808-812.
-
Zhang, B., Sun, Y., Chen, L., Guan, C., Guo, L., & Qin, C.
(2010).
Expression and distribution of SIBLING proteins in the predentin/dentin and mandible of hyp mice. Oral Diseases.
16(5), 453-464.
-
Sun, Y., Lu, Y., Chen, S., Prasad, M., Wang, X., Zhu, Q., ... Qin, C.
(2010).
Key proteolytic cleavage site and full-length form of DSPP. Journal of Dental Research.
89(5), 498-503.
-
Gericke, A., Qin, C., Sun, Y., Redfern, R., Redfern, D., Fujimoto, Y., ... Boskey, A. L.
(2010).
Different forms of DMP1 play distinct roles in mineralization. Journal of Dental Research.
89(4), 355-359.
-
Sun, Y., Gandhi, V., Prasad, M., Yu, W., Wang, X., Zhu, Q., ... Qin, C.
(2010).
Distribution of small integrin-binding ligand, N-linked glycoproteins (SIBLING) in the condylar cartilage of rat mandible. International Journal of Oral and Maxillofacial Surgery.
39(3), 272-281.
-
Prasad, M., Butler, W. T., & Qin, C.
(2010).
Dentin sialophosphoprotein in biomineralization. Connective Tissue Research.
51(5), 404-417.
-
Lin, Y., Cheng, Y., Qin, C., Lin, C., D'Souza, R., & Wang, F.
(2009).
FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors. Developmental Dynamics.
238(2), 324-330.
-
Maciejewska, I., Cowan, C., Svoboda, K., Butler, W. T., D'Souza, R., & Qin, C.
(2009).
The NH2-terminal and COOH-terminal fragments of dentin matrix protein 1 (DMP1) localize differently in the compartments of dentin and growth plate of bone. Journal of Histochemistry and Cytochemistry: imaging the spectrum of cell biology.
57(2), 155-166.
-
Bernards, M. T., Qin, C., Ratner, B. D., & Jiang, S.
(2008).
Adhesion of MC3T3-E1 cells to bone sialoprotein and bone osteopontin specifically bound to collagen I. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A.
86(3), 779-787.
-
Yao, Z., Xing, L., Qin, C., Schwarz, E. M., & Boyce, B. F.
(2008).
Osteoclast precursor interaction with bone matrix induces osteoclast formation directly by an interleukin-1-mediated autocrine mechanism. Journal of Biological Chemistry.
283(15), 9917-9924.
-
Huang, B., Sun, Y., Maciejewska, I., Qin, D., Peng, T., McIntyre, B., ... Qin, C.
(2008).
Distribution of SIBLING proteins in the organic and inorganic phases of rat dentin and bone. European Journal Of Oral Sciences.
116(2), 104-112.
-
Shibata, S., Baba, O., Oda, T., Yokohama-Tamaki, T., Qin, C., Butler, W. T., Sakakura, Y., & Takano, Y.
(2008).
An immunohistochemical and ultrastructural study of the pericellular matrix of uneroded hypertrophic chondrocytes in the mandibular condyle of aged c-src-deficient mice. Archives of Oral Biology.
53(3), 220-230.
-
Qin, C., D'Souza, R., & Feng, J. Q.
(2008).
ERRATUM. Journal of Dental Research.
87(1), 94-94.
-
Chen, S., Chen, L., Jahangiri, A., Chen, B. o., Wu, Y., Chuang, H., Qin, C., & MacDougall, M.
(2008).
Expression and processing of small integrin-binding ligand N-linked glycoproteins in mouse odontoblastic cells. Archives of Oral Biology.
53(9), 879-889.
-
Huang, B., Maciejewska, I., Sun, Y., Peng, T., Qin, D., Lu, Y., ... Qin, C.
(2008).
Identification of full-length dentin matrix protein 1 in dentin and bone. Calcified Tissue International.
82(5), 401-410.
-
Bernards, M. T., Qin, C., & Jiang, S.
(2008).
MC3T3-E1 cell adhesion to hydroxyapatite with adsorbed bone sialoprotein, bone osteopontin, and bovine serum albumin. Colloids and Surfaces B: Biointerfaces.
64(2), 236-247.
-
Qin, C., D'Souza, R., & Feng, J. Q.
(2007).
Dentin matrix protein 1 (DMP1): new and important roles for biomineralization and phosphate homeostasis. Journal of Dental Research.
86(12), 1134-1141.
-
Gajjeraman, S., Narayanan, K., Hao, J., Qin, C., & George, A.
(2007).
Matrix macromolecules in hard tissues control the nucleation and hierarchical assembly of hydroxyapatite. Journal of Biological Chemistry.
282(2), 1193-1204.
-
Zhang, B., Guan, C., Chen, W., Zhang, P., Yan, M., Shi, J., Qin, C., & Yang, Q.
(2007).
A20 inhibits human salivary adenoid cystic carcinoma cells invasion via blocking nuclear factor-kappaB activation. Chinese Medical Journal.
120(20), 1830-1835.
-
Liu, L., Qin, C., Butler, W. T., Ratner, B. D., & Jiang, S.
(2007).
Controlling the orientation of bone osteopontin via its specific binding with collagen I to modulate osteoblast adhesion. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A.
80(1), 102-110.
-
Moses, K. D., Butler, W. T., & Qin, C.
(2006).
Immunohistochemical study of small integrin-binding ligand, N-linked glycoproteins in reactionary dentin of rat molars at different ages. European Journal Of Oral Sciences.
114(3), 216-222.
-
Qin, C., Huang, B., Wygant, J. N., McIntyre, B. W., McDonald, C. H., Cook, R. G., & Butler, W. T.
(2006).
A chondroitin sulfate chain attached to the bone dentin matrix protein 1 NH2-terminal fragment. Journal of Biological Chemistry.
281(12), 8034-8040.
-
He, G., Gajjeraman, S., Schultz, D., Cookson, D., Qin, C., Butler, W. T., Hao, J., & George, A.
(2005).
Spatially and temporally controlled biomineralization is facilitated by interaction between self-assembled dentin matrix protein 1 and calcium phosphate nuclei in solution. Biochemistry.
44(49), 16140-16148.
-
Gericke, A., Qin, C., Spevak, L., Fujimoto, Y., Butler, W. T., Srensen, E. S., & Boskey, A. L.
(2005).
Importance of phosphorylation for osteopontin regulation of biomineralization. Calcified Tissue International.
77(1), 45-54.
-
Rodriguez, A. P., Tsujigiwa, H., Nagatsuka, H., Ichikawa, K., Minonishi, A., Liliana, M., Qin, C. L., & Nagai, N.
(2005).
In Vivo Response of Osteoblast-like and Odontoblast-like Cells in Intraperitoneal Diffusion Chamber. Journal of Hard Tissue Biology.
14(2), 294-295.
-
Qin, C., Baba, O., & Butler, W. T.
(2004).
Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis. Journal of Dental Research.
15(3), 126-136.
-
Tartaix, P. H., Doulaverakis, M., George, A., Fisher, L. W., Butler, W. T., Qin, C., ... Boskey, A. L.
(2004).
In vitro effects of dentin matrix protein-1 on hydroxyapatite formation provide insights into in vivo functions. Journal of Biological Chemistry.
279(18), 18115-18120.
-
Baba, O., Qin, C., Brunn, J. C., Jones, J. E., Wygant, J. N., McIntyre, B. W., & Butler, W. T.
(2004).
Detection of dentin sialoprotein in rat periodontium. European Journal Of Oral Sciences.
112(2), 163-170.
-
Baba, O., Qin, C., Brunn, J. C., Wygant, J. N., McIntyre, B. W., & Butler, W. T.
(2004).
Colocalization of dentin matrix protein 1 and dentin sialoprotein at late stages of rat molar development. Matrix Biology.
23(6), 371-379.
-
Qin, C., Brunn, J. C., Cook, R. G., Orkiszewski, R. S., Malone, J. P., Veis, A., & Butler, W. T.
(2003).
Evidence for the proteolytic processing of dentin matrix protein 1. Identification and characterization of processed fragments and cleavage sites. Journal of Biological Chemistry.
278(36), 34700-34708.
-
Qin, C., Brunn, J. C., Baba, O., Wygant, J. N., McIntyre, B. W., & Butler, W. T.
(2003).
Dentin sialoprotein isoforms: detection and characterization of a high molecular weight dentin sialoprotein. European Journal Of Oral Sciences.
111(3), 235-242.
-
Butler, W. T., Brunn, J. C., & Qin, C.
(2003).
Dentin extracellular matrix (ECM) proteins: comparison to bone ECM and contribution to dynamics of dentinogenesis. Connective Tissue Research.
44 Suppl 1(1), 171-178.
-
Qin, C., Brunn, J. C., Cadena, E., Ridall, A., & Butler, W. T.
(2003).
Dentin sialoprotein in bone and dentin sialophosphoprotein gene expressed by osteoblasts. Connective Tissue Research.
44 Suppl 1(1), 179-183.
-
Qin, C., Brunn, J. C., Cadena, E., Ridall, A., Tsujigiwa, H., Nagatsuka, H., Nagai, N., & Butler, W. T.
(2002).
The expression of dentin sialophosphoprotein gene in bone. Journal of Dental Research.
81(6), 392-394.
-
Razzouk, S., Brunn, J. C., Qin, C., Tye, C. E., Goldberg, H. A., & Butler, W. T.
(2002).
Osteopontin posttranslational modifications, possibly phosphorylation, are required for in vitro bone resorption but not osteoclast adhesion. BONE.
30(1), 40-47.
-
Butler, W. T., Brunn, J. C., Qin, C., & McKee, M. D.
(2002).
Extracellular matrix proteins and the dynamics of dentin formation. Connective Tissue Research.
43(2-3), 301-307.
-
Qin, C., Brunn, J. C., Jones, J., George, A., Ramachandran, A., Gorski, J. P., & Butler, W. T.
(2001).
A comparative study of sialic acid-rich proteins in rat bone and dentin. European Journal Of Oral Sciences.
109(2), 133-141.
-
Qin, C., Cook, R. G., Orkiszewski, R. S., & Butler, W. T.
(2001).
Identification and characterization of the carboxyl-terminal region of rat dentin sialoprotein. Journal of Biological Chemistry.
276(2), 904-909.
-
Nagai, N., Qin, C. L., Nagatsuka, H., Inoue, M., & Ishiwari, Y.
(1999).
Age effects on ectopic bone formation induced by purified bone morphogenetic protein. International Journal of Oral and Maxillofacial Surgery.
28(2), 143-150.
-
Huang, Y., Chen, H., Zhang, H., Lu, Y., & Qin, C.
(2022).
FAM20C plays a critical role in the development of mouse vertebra. The Spine Journal.
22(2), 337-348.
-
chapter
-
Qin, C., & Feng, J. Q.
(2012).
Dentin. Mineralized Tissues in Oral and Craniofacial Science.
(pp. 135-141).
Wiley.
-
Feng, J. Q., & Qin, C.
(2012).
Mineral Metabolism and its Impact on Craniofacial Bones and Teeth. Mineralized Tissues in Oral and Craniofacial Science.
(pp. 297-303).
Wiley.
-
Qin, C., & Feng, J. Q.
(2012).
Dentin. Mineralized Tissues in Oral and Craniofacial Science.
(pp. 135-141).
Wiley.
-
conference paper
-
Peng, T., Huang, B., Sun, Y., Lu, Y., Bonewald, L., Chen, S., ... Qin, C.
(2009).
Blocking of proteolytic processing and deletion of glycosaminoglycan side chain of mouse DMP1 by substituting critical amino acid residues. Cells, Tissues, Organs: in vivo, in vitro.
192-197.
-
Maciejewska, I., Qin, D., Huang, B., Sun, Y., Mues, G., Svoboda, K., ... Qin, C.
(2009).
Distinct compartmentalization of dentin matrix protein 1 fragments in mineralized tissues and cells. Cells, Tissues, Organs: in vivo, in vitro.
186-191.
-
Lu, Y., Qin, C., Xie, Y., Bonewald, L. F., & Feng, J. Q.
(2009).
Studies of the DMP1 57-kDa functional domain both in vivo and in vitro. Cells, Tissues, Organs: in vivo, in vitro.
175-185.
-
Young, C. S., Kim, S., Qin, C., Baba, O., Butler, W. T., Taylor, R. R., ... Yelick, P. C.
(2005).
Developmental analysis and computer modelling of bioengineered teeth. Archives of Oral Biology.
259-265.
-
Peng, T., Huang, B., Sun, Y., Lu, Y., Bonewald, L., Chen, S., ... Qin, C.
(2009).
Blocking of proteolytic processing and deletion of glycosaminoglycan side chain of mouse DMP1 by substituting critical amino acid residues. Cells, Tissues, Organs: in vivo, in vitro.
192-197.
Research
principal investigator on
- The Roles of Fam20c (dmp4) In Odontogenesis and Osteogenesis awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2012 - 2019
- Studies of the Roles of DMP1 and DSPP In Osteogenesis and Dentinogenesis awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2012 - 2015
co-principal investigator on
- Functions of Family with Sequence Similarity 20 - Member C (FAM20C) and Member A (FAM20A) in Amelogenesis and Dentinogenesis awarded by National Institute of Dental and Craniofacial Research - (Bethesda, Maryland, United States) 2020 - 2024
- Dentin Sialophosphoprotein (DSPP) and Unfolded Protein Response (UPR) in Dentinogensis Imperfecta (DGI) and Odontoblast Function awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2018 - 2023
- Tooth Root Formation: An Emerging Signaling Pathway awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2013 - 2016
Teaching
teaching activities
- OBIO606 Oral Histology Instructor
- OBIO613 Interactive Writing & Grants Instructor
- OBIO643 Adv Bio Of Mineralized Tissues Instructor
- OBIO689 Sptp:intratve Writ & Grnt Pros Instructor
Works By Students
chaired theses and dissertations
-
Jani, Priyam Himanshu (2016-12). Biological Functions of Dentin Sialophsphoprotein in Mineralized Tissues.
Background
education and training
- Ph.D. in Dentistry, Okayama University - (Okayama, Okayama, Japan) 1998
- M.S. in Dentistry, Harbin Medical University - (Harbin, Heilongjiang, China) 1989
- D.D.S. in Dentistry, Harbin Medical University - (Harbin, Heilongjiang, China) 1983
- The University of Texas Health Science Center at Houston - (Houston, Texas, United States) , Postdoctoral Training 2003
awards and honors
Contact
first name
- Chunlin
has last name
- Qin
mailing address
-
Texas A&M University College of Dentistry
Biomedical Sciences
3302 Gaston Avenue
Dallas, TX 75246
USA
Other
- chunlinqin@tamu.edu