HR job title
- Vice Chancellor and Dean
- Contact Info
Stover, Patrick Vice Chancellor and Dean
Positions
- Vice Chancellor and Dean, College of Agriculture and Life Sciences
- Overview
- Publications
- Research
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Overview
Publications
selected publications
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academic article
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Miura, N., Matsumoto, H., Cynober, L., Stover, P. J., Elango, R., Kadowaki, M., Bier, D. M., & Smriga, M.
(2021).
Subchronic Tolerance Trials of Graded Oral Supplementation with Phenylalanine or Serine in Healthy Adults. Nutrients.
13(6), 1976-1976.
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Maruvada, P., Stover, P. J., Mason, J. B., Bailey, R. L., Davis, C. D., Field, M. S., ... Zappalà, G.
(2020).
Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop. AMERICAN JOURNAL OF CLINICAL NUTRITION.
112(5), nqaa259--1403.
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Stover, P. J., Garza, C., Durga, J., & Field, M. S.
(2020).
Emerging Concepts in Nutrient Needs. JOURNAL OF NUTRITION.
150(Suppl 1), 2593s-2601s.
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Gheller, B. J., Blum, J. E., Lim, E. W., Handzlik, M. K., Hannah Fong, E. H., Ko, A. C., ... Thalacker-Mercer, A. E.
(2020).
Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function. Molecular Metabolism.
43, 101106-101106.
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Stover, P. J., & King, J. C.
(2020).
More Nutrition Precision, Better Decisions for the Health of Our Nation. JOURNAL OF NUTRITION.
150(12), 3058-3060.
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Chakraborty, J., & Stover, P. J.
(2020).
Deoxyuracil in DNA in health and disease. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE.
23(4), 247-252.
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Fleischhacker, S. E., Woteki, C. E., Coates, P. M., Hubbard, V. S., Flaherty, G. E., Glickman, D. R., ... Mozaffarian, D.
(2020).
Strengthening national nutrition research: rationale and options for a new coordinated federal research effort and authority. AMERICAN JOURNAL OF CLINICAL NUTRITION.
112(3), nqaa179-769.
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Lachenauer, E. R., Stabler, S. P., Field, M. S., & Stover, P. J.
(2020).
p53 Disruption Increases Uracil Accumulation in DNA of Murine Embryonic Fibroblasts and Leads to Folic Acid-Nonresponsive Neural Tube Defects in Mice. JOURNAL OF NUTRITION.
150(7), 1705-1712.
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Misselbeck, K., Marchetti, L., Priami, C., Stover, P. J., & Field, M. S.
(2019).
The 5-formyltetrahydrofolate futile cycle reduces pathway stochasticity in an extended hybrid-stochastic model of folate-mediated one-carbon metabolism. SCIENTIFIC REPORTS.
9(1), 4322.
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Johnston, B. C., Zeraatkar, D., Han, M. A., Vernooij, R., Valli, C., El Dib, R., ... Guyatt, G. H.
(2019).
Unprocessed Red Meat and Processed Meat Consumption: Dietary Guideline Recommendations From the Nutritional Recommendations (NutriRECS) Consortium. ANNALS OF INTERNAL MEDICINE.
171(10), 756-764.
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Balling, R., & Stover, P. J.
(2019).
Addressing the Increased Expectations of Nutrition. Annual Review of Nutrition.
39(1), 1-2.
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Tiani, K. A., Stover, P. J., & Field, M. S.
(2019).
The Role of Brain Barriers in Maintaining Brain Vitamin Levels. Annual Review of Nutrition.
39(1), 1-27.
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Chon, J., Field, M. S., & Stover, P. J.
(2019).
Deoxyuracil in DNA and disease: Genomic signal or managed situation?. DNA Repair.
77, 36-44.
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James, W., Johnson, R. J., Speakman, J. R., Wallace, D. C., Frühbeck, G., Iversen, P. O., & Stover, P. J.
(2019).
Nutrition and its role in human evolution. Journal of Internal Medicine.
285(5), 533-549.
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Rudolph, A., Nusser, S., Stover, P., Mohapatra, P., Wilhelm, R., & Dorhout, P.
(2019).
Lincoln's Biodefense Strategy: Protecting the Agricultural Base. Health Security.
17(1), 80-81.
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Garza, C., Stover, P. J., Ohlhorst, S. D., Field, M. S., Steinbrook, R., Rowe, S., Woteki, C., & Campbell, E.
(2019).
Best practices in nutrition science to earn and keep the public's trust. AMERICAN JOURNAL OF CLINICAL NUTRITION.
109(1), nqy337-243.
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Lan, X. u., Field, M. S., & Stover, P. J.
(2018).
Cell cycle regulation of folate‐mediated one‐carbon metabolism. Wiley Interdisciplinary Reviews Systems Biology and Medicine.
10(6), e1426-e1426.
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Alonzo, J. R., Venkataraman, C., Field, M. S., & Stover, P. J.
(2018).
The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA. J Biol Chem.
293(52), 20285-20294.
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Stover, P. J., James, W., Krook, A., & Garza, C.
(2018).
Emerging concepts on the role of epigenetics in the relationships between nutrition and health. Journal of Internal Medicine.
284(1), 37-49.
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Dixit, R., Nettem, S., Madan, S. S., Soe, H., Abas, A. B., Vance, L. D., & Stover, P. J.
(2018).
Folate supplementation in people with sickle cell disease. Cochrane Database of Systematic Reviews.
3(3), cd011130.
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Field, M. S., Lan, X. u., Stover, D. M., & Stover, P. J.
(2018).
Dietary Uridine Decreases Tumorigenesis in the ApcMin/+ Model of Intestinal Cancer. Current Developments in Nutrition.
2(5), nzy013.
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Misselbeck, K., Marchetti, L., Field, M. S., Scotti, M., Priami, C., & Stover, P. J.
(2017).
A hybrid stochastic model of folate-mediated one-carbon metabolism: Effect of the common C677T MTHFR variant on de novo thymidylate biosynthesis. SCIENTIFIC REPORTS.
7(1), 797.
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Zwart, S. R., Gibson, C. R., Gregory, J. F., Mader, T. H., Stover, P. J., Zeisel, S. H., & Smith, S. M.
(2017).
Astronaut ophthalmic syndrome. FASEB J.
31(9), 3746-3756.
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Hootman, K. C., Trezzi, J., Kraemer, L., Burwell, L. S., Dong, X., Guertin, K. A., ... Cassano, P. A.
(2017).
Erythritol is a pentose-phosphate pathway metabolite and associated with adiposity gain in young adults. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.
114(21), e4233-e4240.
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Palmer, A. M., Kamynina, E., Field, M. S., & Stover, P. J.
(2017).
Folate rescues vitamin B12 depletion-induced inhibition of nuclear thymidylate biosynthesis and genome instability. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.
114(20), e4095-e4102.
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Bae, S., Kamynina, E., Farinola, A. F., Caudill, M. A., Stover, P. J., Cassano, P. A., Berry, R., & Peña‐Rosas, J. P.
(2017).
Provision of folic acid for reducing arsenic toxicity in arsenic‐exposed children and adults. Cochrane Database Syst Rev.
2017(5),
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Bae, S., Chon, J., Field, M. S., & Stover, P. J.
(2017).
Alcohol Dehydrogenase 5 Is a Source of Formate for De Novo Purine Biosynthesis in HepG2 Cells. JOURNAL OF NUTRITION.
147(4), 499-505.
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Stover, P. J., & Mehta, S.
(2017).
Editorial overview: Food biotechnology. Current Opinion in Biotechnology.
44, v-vi.
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Stover, P. J., Durga, J., & Field, M. S.
(2017).
Folate nutrition and blood–brain barrier dysfunction. Current Opinion in Biotechnology.
44, 146-152.
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Kamynina, E., Lachenauer, E. R., DiRisio, A. C., Liebenthal, R. P., Field, M. S., & Stover, P. J.
(2017).
Arsenic trioxide targets MTHFD1 and SUMO-dependent nuclear de novo thymidylate biosynthesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.
114(12), e2319-e2326.
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Chon, J., Stover, P. J., & Field, M. S.
(2017).
Targeting nuclear thymidylate biosynthesis. Molecular Aspects of Medicine.
53, 48-56.
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Kamynina, E., & Stover, P. J.
(2017).
The Roles of SUMO in Metabolic Regulation. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY.
963, 143-168.
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Field, M. S., & Stover, P. J.
(2017).
Safety of folic acid. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES.
1414(1), 59-71.
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Stover, P. J., Berry, R. J., & Field, M. S.
(2016).
Time to Think About Nutrient Needs in Chronic Disease. JAMA Internal Medicine.
176(10), 1451-1452.
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Field, M. S., Kamynina, E., & Stover, P. J.
(2016).
MTHFD1 regulates nuclear de novo thymidylate biosynthesis and genome stability. Biochimie.
126, 27-30.
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Dixit, R., Nettem, S., Madan, S. S., Soe, H., Abas, A. B., Vance, L. D., & Stover, P. J.
(2016).
Folate supplementation in people with sickle cell disease. Cochrane Database of Systematic Reviews.
2(2), cd011130.
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MacFarlane, A. J., Behan, N. A., Field, M. S., Williams, A., Stover, P. J., & Yauk, C. L.
(2015).
Dietary folic acid protects against genotoxicity in the red blood cells of mice. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis.
779, 105-111.
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Finkelstein, J. L., Layden, A. J., & Stover, P. J.
(2015).
Vitamin B-12 and Perinatal Health. Advances in Nutrition.
6(5), 552-563.
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Bailey, L. B., Stover, P. J., McNulty, H., Fenech, M. F., Gregory, J. F., Mills, J. L., ... Raiten, D. J.
(2015).
Biomarkers of Nutrition for Development—Folate Review. JOURNAL OF NUTRITION.
145(7), 1636s-1680s.
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Stover, P. J., MacFarlane, A. J., & Field, M. S.
(2015).
Bringing clarity to the role of MTHFR variants in neural tube defect prevention. AMERICAN JOURNAL OF CLINICAL NUTRITION.
101(6), 1111-1112.
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Nesheim, M., Stover, P. J., & Oria, M.
(2015).
Healthy diet sustains the environment too. NATURE.
522(7556), 287-287.
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Martiniova, L., Field, M. S., Finkelstein, J. L., Perry, C. A., & Stover, P. J.
(2015).
Maternal dietary uridine causes, and deoxyuridine prevents, neural tube closure defects in a mouse model of folate-responsive neural tube defects. AMERICAN JOURNAL OF CLINICAL NUTRITION.
101(4), 860-869.
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Awuah, E., Field, M., & Stover, P.
(2015).
Effects of disrupted serine hydroxymethyltransferase 1 (Shmt1) gene expression on motor function and myelin degeneration in vitamin B12 deficient mice. FASEB J.
29(S1),
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Field, M. S., Kamynina, E., Watkins, D., Rosenblatt, D. S., & Stover, P. J.
(2015).
Human mutations in methylenetetrahydrofolate dehydrogenase 1 impair nuclear de novo thymidylate biosynthesis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.
112(2), 400-405.
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Stover, P. J., & Field, M. S.
(2015).
Vitamin B-6. Advances in Nutrition.
6(1), 132-133.
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Field, M. S., Kamynina, E., Agunloye, O. C., Liebenthal, R. P., Lamarre, S. G., Brosnan, M. E., Brosnan, J. T., & Stover, P. J.
(2014).
Nuclear Enrichment of Folate Cofactors and Methylenetetrahydrofolate Dehydrogenase 1 (MTHFD1) Protect de Novo Thymidylate Biosynthesis during Folate Deficiency*. J Biol Chem.
289(43), 29642-29650.
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Ohlhorst, S. D., Russell, R., Bier, D., Klurfeld, D. M., Li, Z., Mein, J. R., ... Konopka, E.
(2014).
Erratum. AMERICAN JOURNAL OF CLINICAL NUTRITION.
100(3), 988-988.
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MacFarlane, A. J., McEntee, M. F., & Stover, P. J.
(2014).
Azoxymethane-Induced Colon Carcinogenesis in Mice Occurs Independently of De Novo Thymidylate Synthesis Capacity. JOURNAL OF NUTRITION.
144(4), 419-424.
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Field, M., & Stover, P.
(2014).
Dietary uridine supplementation decreases tumor number in Apc(Min/+) mice (829.11). FASEB J.
28(S1),
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Ohlhorst, S. D., Russell, R., Bier, D., Klurfeld, D. M., Li, Z., Mein, J. R., ... Konopka, E.
(2013).
Nutrition research to affect food and a healthy lifespan. Advances in Nutrition.
4(5), 579-584.
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Ohlhorst, S. D., Russell, R., Bier, D., Klurfeld, D. M., Li, Z., Mein, J. R., ... Konopka, E.
(2013).
Nutrition research to affect food and a healthy life span. JOURNAL OF NUTRITION.
143(8), 1349-1354.
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Ohlhorst, S. D., Russell, R., Bier, D., Klurfeld, D. M., Li, Z., Mein, J. R., ... Konopka, E.
(2013).
Nutrition research to affect food and a healthy life span. AMERICAN JOURNAL OF CLINICAL NUTRITION.
98(2), 620-625.
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Ash, J. A., Jiang, X., Malysheva, O. V., Fiorenza, C. G., Bisogni, A. J., Levitsky, D. A., ... Strupp, B. J.
(2013).
Dietary and genetic manipulations of folate metabolism differentially affect neocortical functions in mice. NEUROTOXICOLOGY AND TERATOLOGY.
38, 79-91.
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Abarinov, E. V., Beaudin, A. E., Field, M. S., Perry, C. A., Allen, R. H., Stabler, S. P., & Stover, P. J.
(2013).
Disruption of Shmt1 Impairs Hippocampal Neurogenesis and Mnemonic Function in Mice. JOURNAL OF NUTRITION.
143(7), 1028-1035.
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Scotti, M., Stella, L., Shearer, E. J., & Stover, P. J.
(2013).
Modeling cellular compartmentation in one‐carbon metabolism. Wiley Interdisciplinary Reviews Systems Biology and Medicine.
5(3), 343-365.
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Field, M. S., Shields, K. S., Abarinov, E. V., Malysheva, O. V., Allen, R. H., Stabler, S. P., ... Caudill, M. A.
(2013).
Reduced MTHFD1 Activity in Male Mice Perturbs Folate- and Choline-Dependent One-Carbon Metabolism as Well as Transsulfuration. JOURNAL OF NUTRITION.
143(1), 41-45.
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Wernimont, S. M., Clark, A. G., Stover, P. J., Wells, M. T., Litonjua, A. A., Weiss, S. T., ... Cassano, P. A.
(2012).
Folate Network Genetic Variation Predicts Cardiovascular Disease Risk in Non-Hispanic White Males. JOURNAL OF NUTRITION.
142(7), 1272-1279.
-
Stover, P. J., & Weiss, R. S.
(2012).
Sensitizing Cancer Cells: Is It Really All about U?. Cancer Cell.
22(1), 3-4.
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Swayne, B. G., Behan, N. A., Williams, A., Stover, P. J., Yauk, C. L., & MacFarlane, A. J.
(2012).
Supplemental Dietary Folic Acid Has No Effect on Chromosome Damage in Erythrocyte Progenitor Cells of Mice. JOURNAL OF NUTRITION.
142(5), 813-817.
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Beaudin, A. E., Perry, C. A., Stabler, S. P., Allen, R. H., & Stover, P. J.
(2012).
Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice. AMERICAN JOURNAL OF CLINICAL NUTRITION.
95(4), 882-891.
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Anderson, D. D., Woeller, C. F., Chiang, E., Shane, B., & Stover, P. J.
(2012).
Serine Hydroxymethyltransferase Anchors de Novo Thymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis*. J Biol Chem.
287(10), 7051-7062.
-
Beaudin, A. E., Abarinov, E. V., Malysheva, O., Perry, C. A., Caudill, M., & Stover, P. J.
(2012).
Dietary folate, but not choline, modifies neural tube defect risk in Shmt1 knockout mice. AMERICAN JOURNAL OF CLINICAL NUTRITION.
95(1), 109-114.
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MacFarlane, A. J., Anderson, D. D., Flodby, P., Perry, C. A., Allen, R. H., Stabler, S. P., & Stover, P. J.
(2011).
Nuclear Localization of de Novo Thymidylate Biosynthesis Pathway Is Required to Prevent Uracil Accumulation in DNA*. J Biol Chem.
286(51), 44015-44022.
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Wernimont, S. M., Clark, A. G., Stover, P. J., Wells, M. T., Litonjua, A. A., Weiss, S. T., ... Cassano, P. A.
(2011).
Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study. BMC Medical Genetics.
12(1), 150-150.
-
Stover, P. J., & Field, M. S.
(2011).
Trafficking of Intracellular Folates. Advances in Nutrition.
2(4), 325-331.
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Beaudin, A. E., Abarinov, E. V., Noden, D. M., Perry, C. A., Chu, S., Stabler, S. P., Allen, R. H., & Stover, P. J.
(2011).
Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice. AMERICAN JOURNAL OF CLINICAL NUTRITION.
93(4), 789-798.
-
MacFarlane, A. J., Perry, C. A., McEntee, M. F., Lin, D. M., & Stover, P. J.
(2011).
Mthfd1 is a modifier of chemically induced intestinal carcinogenesis. Carcinogenesis.
32(3), 427-433.
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MacFarlane, A. J., Perry, C. A., McEntee, M. F., Lin, D. M., & Stover, P. J.
(2011).
Shmt1 Heterozygosity Impairs Folate-Dependent Thymidylate Synthesis Capacity and Modifies Risk of Apcmin-Mediated Intestinal Cancer Risk. CANCER RESEARCH.
71(6), 2098-2107.
-
Wernimont, S. M., Raiszadeh, F., Stover, P. J., Rimm, E. B., Hunter, D. J., Tang, W., & Cassano, P. A.
(2011).
Polymorphisms in Serine Hydroxymethyltransferase 1 and Methylenetetrahydrofolate Reductase Interact to Increase Cardiovascular Disease Risk in Humans. JOURNAL OF NUTRITION.
141(2), 255-260.
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Field, M. S., Anderson, D. D., & Stover, P. J.
(2011).
Mthfs is an Essential Gene in Mice and a Component of the Purinosome. Frontiers in Genetics.
2(JUNE), 36.
-
Stover, P. J.
(2011).
Polymorphisms in 1-Carbon Metabolism, Epigenetics and Folate-Related Pathologies. Lifestyle Genomics.
4(5), 293-305.
-
Ching, Y., Munroe, R. J., Moran, J. L., Barker, A. K., Mauceli, E., Fennell, T., ... Schimenti, J. C.
(2010).
High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5. BMC Genet.
11(1), 106-106.
-
Stover, P. J., Harlan, W. R., Hammond, J. A., Hendershot, T., & Hamilton, C. M.
(2010).
PhenX: a toolkit for interdisciplinary genetics research. Current Opinion in Lipidology.
21(2), 136-140.
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Bentley, A. R., Raiszadeh, F., Stover, P. J., Hunter, D. J., Hankinson, S. E., & Cassano, P. A.
(2010).
No association between cSHMT genotypes and the risk of breast cancer in the Nurses' Health Study. European Journal of Clinical Nutrition.
64(1), 108-110.
-
Stover, P. J.
(2010).
Vitamin B12 and older adults. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE.
13(1), 24-27.
-
Stover, P. J.
(2009).
One-Carbon Metabolism–Genome Interactions in Folate-Associated Pathologies. JOURNAL OF NUTRITION.
139(12), 2402-2405.
-
Fox, J. T., Shin, W. K., Caudill, M. A., & Stover, P. J.
(2009).
A UV-responsive Internal Ribosome Entry Site Enhances Serine Hydroxymethyltransferase 1 Expression for DNA Damage Repair*. J Biol Chem.
284(45), 31097-31108.
-
Fox, J. T., & Stover, P. J.
(2009).
Mechanism of the Internal Ribosome Entry Site-mediated Translation of Serine Hydroxymethyltransferase 1*. J Biol Chem.
284(45), 31085-31096.
-
Anderson, D. D., & Stover, P. J.
(2009).
SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis. PLOS ONE.
4(6), e5839-e5839.
-
Beaudin, A. E., & Stover, P. J.
(2009).
Insights into metabolic mechanisms underlying folate‐responsive neural tube defects: A minireview. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY.
85(4), 274-284.
-
Stover, P. J., Ordovas, J. M., McCalla, A., Hammond, J., Maiese, D., Wagner, D., Hamilton, C. M., & Ramos, E.
(2009).
Consensus Measures of Diet for Genome‐wide Association Studies of Gene‐Nutrient Interactions in Health and Disease. FASEB J.
23(S1), lb520-lb520.
-
Field, M. S., Anguera, M. C., Page, R., & Stover, P. J.
(2009).
5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887. Archives of Biochemistry and Biophysics.
481(2), 145-150.
-
MacFarlane, A. J., Perry, C. A., Girnary, H. H., Gao, D., Allen, R. H., Stabler, S. P., Shane, B., & Stover, P. J.
(2009).
Mthfd1 Is an Essential Gene in Mice and Alters Biomarkers of Impaired One-carbon Metabolism*. J Biol Chem.
284(3), 1533-1539.
-
MacFarlane, A. J., Liu, X., Perry, C. A., Flodby, P., Allen, R. H., Stabler, S. P., & Stover, P. J.
(2008).
Cytoplasmic Serine Hydroxymethyltransferase Regulates the Metabolic Partitioning of Methylenetetrahydrofolate but Is Not Essential in Mice*. J Biol Chem.
283(38), 25846-25853.
-
Stover, P. J., & Caudill, M. A.
(2008).
Genetic and Epigenetic Contributions to Human Nutrition and Health: Managing Genome–Diet Interactions. Journal of the Academy of Nutrition and Dietetics.
108(9), 1480-1487.
-
Stover, P. J., & MacFarlane, A. J.
(2008).
Mouse models to elucidate mechanisms of folate‐related cancer pathologies. Nutrition Reviews.
66(s1), s54-s58.
-
Stover, P.
(2008).
Discussion: Folate and vitamin B
12 metabolism: Overview and interaction with riboflavin, vitamin B6 , and polymorphisms. Food and Nutrition Bulletin. 29(2 SUPPL.),
-
Fox, J. T., & Stover, P. J.
(2008).
Chapter 1 Folate‐Mediated One‐Carbon Metabolism. FOLIC ACID AND FOLATES.
79, 1-44.
-
Macfarlane, A. J., & Stover, P. J.
(2007).
Convergence of Genetic, Nutritional and Inflammatory Factors in Gastrointestinal Cancers. Nutrition Reviews.
65(SUPPL.3), S157-S166.
-
Anderson, D. D., Woeller, C. F., & Stover, P. J.
(2007).
Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase. Clinical Chemistry and Laboratory Medicine.
45(12), 1760-1763.
-
Woeller, C. F., Fox, J. T., Perry, C., & Stover, P. J.
(2007).
A Ferritin-responsive Internal Ribosome Entry Site Regulates Folate Metabolism*. J Biol Chem.
282(41), 29927-29935.
-
Beaudin, A. E., & Stover, P. J.
(2007).
Folate‐mediated one‐carbon metabolism and neural tube defects: Balancing genome synthesis and gene expression. Birth Defects Research Part C Embryo Today Reviews.
81(3), 183-203.
-
Perry, C., Yu, S., Chen, J., Matharu, K. S., & Stover, P. J.
(2007).
Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells. Archives of Biochemistry and Biophysics.
462(1), 21-27.
-
Woeller, C. F., Anderson, D. D., Szebenyi, D., & Stover, P. J.
(2007).
Evidence for Small Ubiquitin-like Modifier-dependent Nuclear Import of the Thymidylate Biosynthesis Pathway*. J Biol Chem.
282(24), 17623-17631.
-
Stover, P. J.
(2007).
Human Nutrition and Genetic Variation. Food and Nutrition Bulletin.
28(1_suppl1), s101-s115.
-
Stover, P. J.
(2007).
Human nutrition and genetic variation. Food and Nutrition Bulletin.
28(1 SUPPL. 1),
-
Field, M. S., Szebenyi, D., Perry, C. A., & Stover, P. J.
(2007).
Inhibition of 5,10-methenyltetrahydrofolate synthetase. Archives of Biochemistry and Biophysics.
458(2), 194-201.
-
Anguera, M. C., & Stover, P. J.
(2006).
Methenyltetrahydrofolate synthetase is a high-affinity catecholamine-binding protein. Archives of Biochemistry and Biophysics.
455(2), 175-187.
-
Anguera, M. C., Field, M. S., Perry, C., Ghandour, H., Chiang, E., Selhub, J., Shane, B., & Stover, P. J.
(2006).
Regulation of Folate-mediated One-carbon Metabolism by 10-Formyltetrahydrofolate Dehydrogenase*. J Biol Chem.
281(27), 18335-18342.
-
Stover, P. J., & Garza, C.
(2006).
Nutrition and Developmental Biology—Implications for Public Health. Nutrition Reviews.
64(5), 60-71.
-
Stover, P. J.
(2006).
Influence of human genetic variation on nutritional requirements. AMERICAN JOURNAL OF CLINICAL NUTRITION.
83(2), 436s-442s.
-
Field, M. S., Szebenyi, D., & Stover, P. J.
(2006).
Regulation of de Novo Purine Biosynthesis by Methenyltetrahydrofolate Synthetase in Neuroblastoma*. J Biol Chem.
281(7), 4215-4221.
-
Lim, U., Peng, K., Shane, B., Stover, P. J., Litonjua, A. A., Weiss, S. T., ... Cassano, P. A.
(2005).
Polymorphisms in cytoplasmic serine hydroxymethyltransferase and methylenetetrahydrofolate reductase affect the risk of cardiovascular disease in men. JOURNAL OF NUTRITION.
135(8), 1989-1994.
-
Perry, C., Sastry, R., Nasrallah, I. M., & Stover, P. J.
(2005).
Mimosine Attenuates Serine Hydroxymethyltransferase Transcription by Chelating Zinc IMPLICATIONS FOR INHIBITION OF DNA REPLICATION*. J Biol Chem.
280(1), 396-400.
-
Anguera, M. C., Liu, X., & Stover, P. J.
(2004).
Cloning, expression, and purification of 5,10-methenyltetrahydrofolate synthetase from Mus musculus. Protein Expression and Purification.
35(2), 276-283.
-
Stover, P. J.
(2004).
Nutritional genomics. Physiol Genomics.
16(2), 161-165.
-
Stover, P. J.
(2003).
New Paradigms for Nutrient Control of Genome Translation. Nutrition Reviews.
61(12), 427-431.
-
Anguera, M. C., Suh, J. R., Ghandour, H., Nasrallah, I. M., Selhub, J., & Stover, P. J.
(2003).
Methenyltetrahydrofolate Synthetase Regulates Folate Turnover and Accumulation*. J Biol Chem.
278(32), 29856-29862.
-
Zanetti, K. A., & Stover, P. J.
(2003).
Pyridoxal Phosphate Inhibits Dynamic Subunit Interchange among Serine Hydroxymethyltransferase Tetramers*. J Biol Chem.
278(12), 10142-10149.
-
Herbig, K., Chiang, E., Lee, L., Hills, J., Shane, B., & Stover, P. J.
(2002).
Cytoplasmic Serine Hydroxymethyltransferase Mediates Competition between Folate-dependent Deoxyribonucleotide andS-Adenosylmethionine Biosyntheses*. J Biol Chem.
277(41), 38381-38389.
-
Herbig, A. K., & Stover, P. J.
(2002).
Nutrition and developmental biology. Annales Nestle.
60(1), 1-11.
-
Allen, L. H., Bentley, M. E., Donovan, S. M., Ney, D. M., & Stover, P. J.
(2002).
Securing the Future of Nutritional Sciences Through Integrative Graduate Education. JOURNAL OF NUTRITION.
132(4), 779-784.
-
Hirschberger, L. L., Daval, S., Stover, P. J., & Stipanuk, M. H.
(2001).
Murine cysteine dioxygenase gene: structural organization, tissue-specific expression and promoter identification. GENE.
277(1-2), 153-161.
-
Zhao, R., Chen, Y., Tan, W., Waly, M., Sharma, A., Stover, P., ... Deth, R. C.
(2001).
Relationship between dopamine‐stimulated phospholipid methylation and the single‐carbon folate pathway. JOURNAL OF NEUROCHEMISTRY.
78(4), 788-796.
-
Suh, J. R., Herbig, A. K., & Stover, P. J.
(2001).
NEW PERSPECTIVES ON FOLATE CATABOLISM. Annual Review of Nutrition.
21(1), 255-282.
-
Oppenheim, E. W., Adelman, C., Liu, X., & Stover, P. J.
(2001).
Heavy Chain Ferritin Enhances Serine Hydroxymethyltransferase Expression and de Novo Thymidine Biosynthesis*. J Biol Chem.
276(23), 19855-19861.
-
Liu, X., Szebenyi, D., Anguera, M. C., Thiel, D. J., & Stover, P. J.
(2001).
Lack of Catalytic Activity of a Murine mRNA Cytoplasmic Serine Hydroxymethyltransferase Splice Variant: Evidence against Alternative Splicing as a Regulatory Mechanism †. BIOCHEMISTRY.
40(16), 4932-4939.
-
Suh, J. R., Oppenheim, E. W., Girgis, S., & Stover, P. J.
(2000).
Purification and Properties of a Folate-catabolizing Enzyme*. J Biol Chem.
275(45), 35646-35655.
-
Liu, X., Reig, B., Nasrallah, I. M., & Stover, P. J.
(2000).
Human cytoplasmic serine hydroxymethyltransferase is an mRNA binding protein. BIOCHEMISTRY.
39(38), 11523-11531.
-
Oppenheim, E. W., Nasrallah, I. M., Mastri, M. G., & Stover, P. J.
(2000).
Mimosine Is a Cell-specific Antagonist of Folate Metabolism*. J Biol Chem.
275(25), 19268-19274.
-
Liu, X., Reig, B., Nasrallah, I. M., & Stover, P. J.
(2000).
Human Cytoplasmic Serine Hydroxymethyltransferase Is an mRNA Binding Protein †. BIOCHEMISTRY.
39(38), 11523-11531.
-
Szebenyi, D., Liu, X., Kriksunov, I. A., Stover, P. J., & Thiel, D. J.
(2000).
Structure of a Murine Cytoplasmic Serine Hydroxymethyltransferase Quinonoid Ternary Complex: Evidence for Asymmetric Obligate Dimers †. BIOCHEMISTRY.
39(44), 13313-13323.
-
Girgis, S., Nasrallah, I. M., Suh, J. R., Oppenheim, E., Zanetti, K. A., Mastri, M. G., & Stover, P. J.
(1998).
Molecular cloning, characterization and alternative splicing of the human cytoplasmic serine hydroxymethyltransferase gene1The sequences reported in this paper have been deposited in the GenBank Database (Accession Nos AF017064 and AF017065).1. GENE.
210(2), 315-324.
-
Nasrallah, I. M., Girgis, S., & Stover, P. J.
(1997).
Structural comparison of the human mitochondrial and cytoplasmic serine hydroxymethyltransferase genes. FASEB J.
11(9), A1377-A1377.
-
Girgis, S., Suh, J. R., Jolivet, J., & Stover, P. J.
(1997).
5-Formyltetrahydrofolate Regulates Homocysteine Remethylation in Human Neuroblastoma*. J Biol Chem.
272(8), 4729-4734.
-
Stover, P. J., Chen, L. H., Suh, J. R., Stover, D. M., Keyomarsi, K., & Shane, B.
(1997).
Molecular Cloning, Characterization, and Regulation of the Human Mitochondrial Serine Hydroxymethyltransferase Gene*. J Biol Chem.
272(3), 1842-1848.
-
Elsea, S. H., Juyal, R. C., Jiralerspong, S., Finucane, B. M., Pandolfo, M., Greenberg, F., ... Patel, P. I.
(1995).
Haploinsufficiency of cytosolic serine hydroxymethyltransferase in the Smith-Magenis syndrome. AMERICAN JOURNAL OF HUMAN GENETICS.
57(6), 1342-1350.
-
Maras, B., Stover, P., Valiante, S., Barra, D., & Schirch, V.
(1994).
Primary structure and tetrahydropteroylglutamate binding site of rabbit liver cytosolic 5,10-methenyltetrahydrofolate synthetase. J Biol Chem.
269(28), 18429-18433.
-
Stover, P., Kruschwitz, H., Schirch, V., & Wright, H. T.
(1993).
Diffraction Grade Crystals of Escherichia coli Serine Hydroxymethyltransferase. JOURNAL OF MOLECULAR BIOLOGY.
230(3), 1094-1096.
-
Stover, P., & Schirch, V.
(1993).
The metabolic role of leucovorin. Trends in Biochemical Sciences.
18(3), 102-106.
-
Stover, P., Zamora, M., Shostak, K., Gautam-Basak, M., & Schirch, V.
(1992).
Escherichia coli serine hydroxymethyltransferase. The role of histidine 228 in determining reaction specificity. J Biol Chem.
267(25), 17679-17687.
-
Stover, P., & Schirch, V.
(1992).
Synthesis of (6S)-5-formyltetrahydropteroyl-polyglutamates and interconversion to other reduced pteroylpolyglutamate derivatives. ANALYTICAL BIOCHEMISTRY.
202(1), 82-88.
-
Stover, P., & Schirch, V.
(1992).
Enzymatic mechanism for the hydrolysis of 5,10-methenyltetrahydropteroylglutamate to 5-formyltetrahydropteroylglutamate by serine hydroxymethyltransferase. BIOCHEMISTRY.
31(7), 2155-2164.
-
Stover, P., & Schirch, V.
(1992).
Evidence for the accumulation of a stable intermediate in the nonenzymatic hydrolysis of 5,10-methenyltetrahydropteroylglutamate to 5-formyltetrahydropteroylglutamate. BIOCHEMISTRY.
31(7), 2148-2155.
-
Stover, P., & Schirch, V.
(1991).
5-Formyltetrahydrofolate polyglutamates are slow tight binding inhibitors of serine hydroxymethyltransferase. J Biol Chem.
266(3), 1543-1550.
-
Stover, P., & Schirch, V.
(1990).
Serine hydroxymethyltransferase catalyzes the hydrolysis of 5,10-methenyltetrahydrofolate to 5-formyltetrahydrofolate. J Biol Chem.
265(24), 14227-14233.
-
Miura, N., Matsumoto, H., Cynober, L., Stover, P. J., Elango, R., Kadowaki, M., Bier, D. M., & Smriga, M.
(2021).
Subchronic Tolerance Trials of Graded Oral Supplementation with Phenylalanine or Serine in Healthy Adults. Nutrients.
13(6), 1976-1976.
-
book
-
Field, M. S., Kamynina, E., Chon, J., & Stover, P. J.
(2018).
Nuclear Folate Metabolism. Ed. 38.
Annual Reviews.
-
Field, M. S., Kamynina, E., Chon, J., & Stover, P. J.
(2018).
Nuclear Folate Metabolism. Ed. 38.
Annual Reviews.
-
chapter
-
MacFarlane, A. J., & Stover, P. J.
(2017).
Gastrointestinal Disorders: Overview. International Encyclopedia of Public Health.
(pp. 223-232).
Elsevier.
-
Field, M. S., Stover, P. J., & Kisliuk, R.
(2016).
Thymidylate Synthesis. eLS.
(pp. 1-7).
John Wiley & Sons, Ltd.
-
Stover, P. J.
(2012).
Folic acid. Modern Nutrition in Health and Disease: Eleventh Edition.
(pp. 358-368).
-
Stover, P. J., & Gu, Z.
(2012).
Genetic variation: Effect on nutrient utilization and metabolism. Modern Nutrition in Health and Disease: Eleventh Edition.
(pp. 523-533).
-
Stover, P. J.
(2011).
Folate, Vitamin B12, and Vitamin B6. Nutrition in Epigenetics.
(pp. 209-223).
Wiley-Blackwell.
-
Stover, P. J., Twigt, J. M., Laven, J., Steegers-Theunissen, R., Gorman, E. B., Finnell, R. H., ... Rozen, R.
(2011).
Vitamin B9 - folate. Vitamins in the Prevention of Human Diseases.
(pp. 91-186).
DE GRUYTER.
-
Anderson, D. D., & Stover, P. J.
(2009).
The Roles of SUMO in Metabolic Regulation. SUMO Regulation of Cellular Processes.
(pp. 137-149).
Springer Netherlands.
-
MacFarlane, A. J., & Stover, P. J.
(2008).
Gastrointestinal Disorders: Overview. International Encyclopedia of Public Health.
(pp. 9-19).
Elsevier.
-
Herbig, A. K., Girgis, S., & Stover, P. J.
(2002).
Effects of Cellular Glycine on Cell Proliferation. Chemistry and Biology of Pteridines and Folates.
(pp. 491-494).
Springer US.
-
Anguera, M. C., & Stover, P. J.
(2002).
Rapid Purification of the T-Protein of the Glycine Cleavage System from Rabbit Liver. Chemistry and Biology of Pteridines and Folates.
(pp. 485-489).
Springer US.
-
MacFarlane, A. J., & Stover, P. J.
(2017).
Gastrointestinal Disorders: Overview. International Encyclopedia of Public Health.
(pp. 223-232).
Elsevier.
-
conference paper
-
Cynober, L., Bier, D. M., Stover, P., Kadowaki, M., Morris, S. M., Elango, R., & Smriga, M.
(2020).
Proposals for Upper Limits of Safe Intake for Methionine, Histidine, and Lysine in Healthy Humans. JOURNAL OF NUTRITION.
2606s-2608s.
-
Lachenauer, E. R., Stabler, S. P., Field, M. S., & Stover, P. J.
(2019).
p53 Disruption Increases Uracil Accumulation in DNA and Leads to Folic Acid Nonresponsive Neural Tube Defects in Mice. BIRTH DEFECTS RESEARCH.
503-503.
-
Lachenauer, E. R., Kamynina, E., Kraemer, L., Dirisio, A. C., Stabler, S. P., Brosnan, M. E., ... Stover, P. J.
(2018).
Arsenic Exposure Alters Folate Metabolism Causing Genomic Instability and Neural Tube Defects in a Dose-Dependent Manner. BIRTH DEFECTS RESEARCH.
760-760.
-
Brannon, P. M., Stover, P. J., & Taylor, C. L.
(2017).
Integrating themes, evidence gaps, and research needs identified by workshop on iron screening and supplementation in iron-replete pregnant women and young children. AMERICAN JOURNAL OF CLINICAL NUTRITION.
1703s-1712s.
-
Chon, J., Gondokusumo, J. C., Field, M. S., & Stover, P. J.
(2017).
De novo Thymidylate Biosynthesis and dUTPase Interact in DNA Synthesis. FASEB J.
-
Stover, P., Ohlhorst, S., Field, M., & Garza, C.
(2017).
BEST PRACTICES FROM THE ASN COMMITTEE ON PUBLIC TRUST. ANNALS OF NUTRITION AND METABOLISM.
142-142.
-
Chon, J., Field, M., Gondokusumo, J., & Stover, P.
(2016).
Identifying the role of genomic uracil in folate deficiency. FASEB J.
-
Chon, J., Field, M., Gondokusumo, J., & Stover, P.
(2016).
Identifying the role of genomic uracil in folate deficiency. FASEB J.
-
DiRisio, A., Kamynina, E., Field, M. S., & Stover, P. J.
(2016).
The Effects of Folate Deficiency and Arsenic Exposure on Thymidylate Synthesis in Serine Hydroxymethyltransferase 1-Deficient Mouse Embryonic Fibroblasts. FASEB J.
-
DiRisio, A., Kamynina, E., & Stover, P.
(2015).
The Role of Serine Hydroxymethyltransferase and Methylene‐Tetrahydrofolate Dehydrogenase in Genome Stability. FASEB J.
-
Romagnolo, D. F., Dashwood, R., Stover, P. J., Waterland, R. A., & Ziegler, T. R.
(2012).
Nutritional Regulation of Epigenetic Changes. Advances in Nutrition.
749-750.
-
Yetley, E. A., Pfeiffer, C. M., Phinney, K. W., Fazili, Z., Lacher, D. A., Bailey, R. L., ... Picciano, M. F.
(2011).
Biomarkers of folate status in NHANES: a roundtable summary123456. AMERICAN JOURNAL OF CLINICAL NUTRITION.
303s-312s.
-
Yetley, E. A., Pfeiffer, C. M., Phinney, K. W., Bailey, R. L., Blackmore, S., Bock, J. L., ... Picciano, M. F.
(2011).
Biomarkers of vitamin B-12 status in NHANES: a roundtable summary123456. AMERICAN JOURNAL OF CLINICAL NUTRITION.
313s-321s.
-
Stover, P. J.
(2004).
Physiology of folate and vitamin B
12 in health and disease. Nutrition Reviews.
-
Garza, C., & Stover, P.
(2003).
1. General introduction the role of science in identifying common ground in the debate on genetic modification of foods. Trends in Food Science & Technology.
182-190.
-
Stover, P. J., & Garza, C.
(2002).
Molecular and genetic considerations for long‐term nutrition interventions. Asia Pacific Journal of Clinical Nutrition.
s129-s136.
-
Stover, P. J., & Garza, C.
(2002).
Bringing individuality to public health recommendations. JOURNAL OF NUTRITION.
-
Stover, P., Kruschwitz, H., & Schirch, V.
(1993).
Evidence that 5-Formyltetrahydropteroylglutamate has a Metabolic Role in One-Carbon Metabolism. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY.
679-685.
-
Shane, B., Garrow, T., Brenner, A., Chen, L., Choi, Y., Hsu, J., & Stover, P.
(1993).
Folylpoly-γ-Glutamate Synthetase. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY.
629-634.
-
Stover, P., Huang, T., Schirch, V., Maras, B., Valiante, S., & Barra, D.
(1993).
Purification and Properties of Rabbit Liver 5,10-Methenyltetrahydrofolate Synthetase. ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY.
723-726.
-
Cynober, L., Bier, D. M., Stover, P., Kadowaki, M., Morris, S. M., Elango, R., & Smriga, M.
(2020).
Proposals for Upper Limits of Safe Intake for Methionine, Histidine, and Lysine in Healthy Humans. JOURNAL OF NUTRITION.
2606s-2608s.
Research
awards and honors
Background
education and training
- Ph.D. in Biochemistry & Molecular Biophysics, Virginia Commonwealth University - (Richmond, Virginia, United States) 1990
- B.S. in Chemistry, Saint Joseph's University - (Philadelphia, Pennsylvania, United States) 1986
Contact
first name
- Patrick
has last name
- Stover
mailing address
-
Texas A&M AgriLife Research
Vice Chancellor of Agriculture - Management
2147 TAMUS
College Station, TX 77843-2147
USA
Other
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- patrick.stover@tamu.edu