New paradigms for nutrient control of genome translation. Academic Article

abstract

• Organisms respond adaptively to changing environmental conditions by altering genome expression. Translational control of gene expression by nutrients and metabolites is one of the most robust biologic mechanisms that enable rapid alterations in the cellular proteome in response to changes in the local environment. Recently, investigators have identified new mechanisms for nutrient control of translation in mammals; evidence supports the conservation of translational control mechanisms in eukaryotes that heretofore had only been demonstrated in prokaryotes.

authors

• Stover, Patrick

published proceedings

• Nutr Rev

author list (cited authors)

• Stover, P. J.

citation count

• 3

complete list of authors

• Stover, Patrick J

publication date

• December 2003

publisher

• Oxford University Press (OUP)  Publisher

published in

• Nutrition Reviews  Journal

keywords

• Eukaryotic Cells
• Eukaryotic Initiation Factor-4f
• Gene Expression Regulation
• Genome, Human
• Humans
• Micronutrients
• Protein Biosynthesis
• RNA, Messenger
• Transcription, Genetic

PubMed Central ID

• 14968913

Digital Object Identifier (DOI)

• 10.1301/nr.2003.dec.427-431

start page

• 427

end page

• 431

volume

• 61

issue

• 12

URL

• http://dx.doi.org/10.1301/nr.2003.dec.427-431