selected publications academicarticle Srivatsa Palakurthi, S., Bharat Charbe, N., Recalde Phillips, S. Y., Alge, D. L., Lu, D., & Palakurthi, S. (2023). Development of optimal in vitro release and permeation testing method for rectal suppositories. 640, 123042-123042. Charbe, N. B., Tambuwala, M., Palakurthi, S. S., Warokar, A., Hromi-Jahjefendi, A., Bakshi, H., ... Palakurthi, S. (2023). Biomedical applications of three-dimensional bioprinted craniofacial tissue engineering. Bioengineering and Translational Medicine. 8(1), e10333. Renukuntla, J., Palakurthi, S. S., Bolla, P. K., Clark, B. A., Boddu, S., Manda, P., ... Palakurthi, S. (2022). Advances in in-vitro bioequivalence testing methods for complex ophthalmic generic products. International Journal of Pharmaceutics. 627, 122209-122209. Venkata, P. P., Chen, Y., Alejo, S., He, Y. i., Palacios, B. E., Loeffel, I., ... Sareddy, G. R. (2022). KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer. Cancer Letters. 524, 219-231. Khare, T., Palakurthi, S. S., Shah, B. M., Palakurthi, S., & Khare, S. (2020). Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease. International Journal of Molecular Sciences. 21(11), 3956-3956. Shah, B. M., Palakurthi, S. S., Khare, T., Khare, S., & Palakurthi, S. (2020). Natural proteins and polysaccharides in the development of micro/nano delivery systems for the treatment of inflammatory bowel disease. International Journal of Biological Macromolecules. 165(Pt A), 722-737. Vaidya, B., Shukla, S. K., Kolluru, S., Huen, M., Mulla, N., Mehra, N., ... Gupta, V. (2019). Nintedanib-cyclodextrin complex to improve bio-activity and intestinal permeability. Carbohydrate Polymers. 204, 68-77. Mehra, N. K., Tekmal, R. R., & Palakurthi, S. (2018). Development and Evaluation of Talazoparib Nanoemulsion for Systemic Therapy of BRCA1-mutant Cancer. Anticancer Research: international journal of cancer research and treatment. 38(8), 4493-4503. Hidau, M. K., Kolluru, S., & Palakurthi, S. (2018). Development and validation of a high-performance liquid chromatography method for the quantification of talazoparib in rat plasma: Application to plasma protein binding studies. Biomedical Chromatography. 32(2), e4046-e4046. Palakurthi, S., Kolluru, S., Mehra, N., & Hidau, M. (2017). Cyclodextrin Complexation of Meclizine Hydrochloride and its Influence on the Solubility for its Repurposing. Drug Delivery Letters. 7(1), 54-61. Wei, Z., Maganti, M., Martinez, B., Vangara, K. K., Palakurthi, S., Luo, Z., ... Liu, J. (2016). Biological study of metal-organic frameworks towards human ovarian cancer cell lines. Canadian Journal of Chemistry. 94(4), 380-385. Mehra, N. K., & Palakurthi, S. (2016). Interactions between carbon nanotubes and bioactives: a drug delivery perspective. Drug Discovery Today. 21(4), 585-597. Yellepeddi, V. K., & Palakurthi, S. (2016). Recent Advances in Topical Ocular Drug Delivery. Journal of Ocular Pharmacology and Therapeutics. 32(2), 67-82. Mehra, N. K., Cai, D., Kuo, L., Hein, T., & Palakurthi, S. (2016). Safety and toxicity of nanomaterials for ocular drug delivery applications. Nanotoxicology. 10(7), 836-860. Palakurthi, S. (2015). Challenges in SN38 drug delivery: current success and future directions. Expert Opinion on Drug Delivery. 12(12), 1911-1921. Vangara, K. K., Ali, H. I., Lu, D., Liu, J. L., Kolluru, S., & Palakurthi, S. (2014). SN-38-cyclodextrin complexation and its influence on the solubility, stability, and in vitro anticancer activity against ovarian cancer. AAPS PharmSciTech. 15(2), 472-482. Paliwal, R., Babu, R. J., & Palakurthi, S. (2014). Nanomedicine scale-up technologies: feasibilities and challenges. AAPS PharmSciTech. 15(6), 1527-1534. Mishra, M. N., Vangara, K. K., & Palakurthi, S. (2014). Transcriptional targeting of human liver carboxylesterase (hCE1m6) and simultaneous expression of anti-BCRP shRNA enhances sensitivity of breast cancer cells to CPT-11. Anticancer Research: international journal of cancer research and treatment. 34(11), 6345-6351. Paliwal, R., & Palakurthi, S. (2014). Zein in controlled drug delivery and tissue engineering. Journal of Controlled Release. 189, 108-122. Yellepeddi, V. K., Vangara, K. K., & Palakurthi, S. (2013). Poly(amido)amine (PAMAM) dendrimer-cisplatin complexes for chemotherapy of cisplatin-resistant ovarian cancer cells. Journal of Nanoparticle Research. 15(9), 1897. Vangara, K. K., Liu, J. L., & Palakurthi, S. (2013). Hyaluronic acid-decorated PLGA-PEG nanoparticles for targeted delivery of SN-38 to ovarian cancer. Anticancer Research: international journal of cancer research and treatment. 33(6), 2425-2434. Kumar, A., & Palakurthi, S. (2013). P53 Gene Therapy Sensitizes Resistant Breast Cancer Cells to Doxorubicin Chemotherapy. Drug Delivery Letters. 3(3), 165-174. Yellepeddi, V. K., & Vangara, K. K. (2013). In vivo Efficacy of PAMAM-Dendrimer-Cisplatin Complexes in SKOV-3 Xenografted Balb/C Nude Mice. Journal of Biotechnology and Biomaterials. 2013. Sethi, R., Manchanda, S., Perepu, R., Kumar, A., Garcia, C., Kennedy, R. H., Palakurthi, S., & Dostal, D. (2012). Differential expression of caveolin-1 and caveolin-3: potential marker for cardiac toxicity subsequent to chronic ozone inhalation. MOLECULAR AND CELLULAR BIOCHEMISTRY. 369(1-2), 9-15. Yellepeddi, V. K., Vangara, K. K., Kumar, A., & Palakurthi, S. (2012). Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells. Anticancer Research: international journal of cancer research and treatment. 32(9), 3651-3658. Palakurthi, S., Yellepeddi, V. K., & Vangara, K. K. (2012). Recent trends in cancer drug resistance reversal strategies using nanoparticles. Expert Opinion on Drug Delivery. 9(3), 287-301. Kumar, A., Yellepeddi, V. K., Vangara, K. K., Strychar, K. B., & Palakurthi, S. (2011). Mechanism of gene transfection by polyamidoamine (PAMAM) dendrimers modified with ornithine residues. Journal of Drug Targeting. 19(9), 770-780. Yellepeddi, V. K., Kumar, A., Maher, D. M., Chauhan, S. C., Vangara, K. K., & Palakurthi, S. (2011). Biotinylated PAMAM dendrimers for intracellular delivery of cisplatin to ovarian cancer: role of SMVT. Anticancer Research: international journal of cancer research and treatment. 31(3), 897-906. Kumar, A., Yellepeddi, V. K., Davies, G. E., Strychar, K. B., & Palakurthi, S. (2010). Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues. International Journal of Pharmaceutics. 392(1-2), 294-303. Yellepeddi, V. K., Kumar, A., & Palakurthi, S (2009). Biotinylated poly(amido)amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro. Anticancer Research: international journal of cancer research and treatment. 29(8), 2933-2943. Zhao, Y., Seefeldt, T., Chen, W., Carlson, L., Stoebner, A., Hanson, S., ... Guan, X. (2009). Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation. Free Radical Biology and Medicine. 47(2), 176-183. Yellepeddi, V. K., Kumar, A., & Palakurthi, S. (2009). Surface modified poly(amido)amine dendrimers as diverse nanomolecules for biomedical applications. Expert Opinion on Drug Delivery. 6(8), 835-850. Palakurthi, S., Wilson, J., McQuarrie, S. A., Suresh, M. R., Mercer, J. R., & Miller, G. G. (2008). Target specificity of 188Re-labeled B27.1 monoclonal antibodies to ovarian cancer cells in vivo. In Vivo: international journal of experimental and clinical pathophysiology and drug research. 22(3), 321-326. Pisal, D. S., Yellepeddi, V. K., Kumar, A., Kaushik, R. S., Hildreth, M. B., Guan, X., & Palakurthi, S. (2008). Permeability of surface-modified polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers. International Journal of Pharmaceutics. 350(1-2), 113-121. Pisal, D. S., Yellepeddi, V. K., Kumar, A., & Palakurthi, S. (2008). Transport of surface engineered polyamidoamine (PAMAM) dendrimers across IPEC-J2 cell monolayers. Drug Delivery. 15(8), 515-522. Palakurthi, S., Mcquarrie, S. A., & Suresh, M. R. (2007). Screening of 14C-polyamines in the AT3B-1 rat prostate tumor model: the search for a new PET prostate imaging agent. In Vivo: international journal of experimental and clinical pathophysiology and drug research. 21(5), 823-828. Palakurthi, S., Vyas, S. P., & Diwan, P. V. (2005). Biodisposition of PEG-coated lipid microspheres of indomethacin in arthritic rats. International Journal of Pharmaceutics. 290(1-2), 55-62. Srinath, P., Rao, P. N., Knaus, E. E., & Suresh, M. R. (2003). Effect of cyclooxygenase-2 (COX-2) inhibitors on prostate cancer cell proliferation. 23(5A), 3923-3928. Srinath, P., McQuarrie, S. A., & Suresh, M. R. (2002). Comparative uptake of polyamines by prostate and non-prostate cancer cell lines. Nuclear Medicine and Biology. 29(4), 497-503. Palakurthi, S., Govardhanachary, M., Vyas, S. P., & Diwan, P. V. (2000). Biodistribution of liposomes of terbutaline sulfate in guinea pigs. 26(10), 1099-1105. Srinath, P., Chary, M. G., Vyas, S. P., & Diwan, P. V. (2000). Long-circulating liposomes of indomethacin in arthritic rats--a biodisposition study. Pharmaceutica acta Helvetiae. 74(4), 399-404. Srinath, P., Vyas, S. P., & Diwan, P. V. (2000). Preparation and pharmacodynamic evaluation of liposomes of indomethacin. 26(3), 313-321. SRINATH, P., VYAS, S. P., & DIWAN, P. V. (1999). Effect of Lipid Composition of Liposomes on Biodisposition of Indomethacin in Arthritic Rats. Journal of Pharmacy and Pharmacology. 5(5), 339-344. Srinath, P., & Diwan, P. V. (1998). Pharmacodynamic and pharmacokinetic evaluation of lipid microspheres of indomethacin. Pharmaceutica acta Helvetiae. 73(4), 199-203. Palakurthi, S. S., Shah, B., Kapre, S., Charbe, N., Immanuel, S., Pasham, S., ... Palakurthi, S. A comprehensive review of challenges and advances in exosome-based drug delivery systems. NANOSCALE ADVANCES. book Bashir, S., Palakurthi, S., Zhou, H. C., & Liu, J. (2014). Nanometals and complexes in cancer diagnosis and therapy Bashir, S., Palakurthi, S., Zhou, H. C., & Liu, J. Handbook of Metallonutraceuticals. CRC Press. chapter Bashir, S., Chava, S. R., Yuan, D., Palakurthi, S., & Liu, J. (2020). Metal-organic frameworks and exemplified cytotoxicity evaluation. METAL-ORGANIC FRAMEWORKS FOR BIOMEDICAL APPLICATIONS. (pp. 347-381). Elsevier. Palakurthi, S., Yellepeddi, V. K., & Kumar, A. (2011). Nanocarriers for Cytosolic Drug and Gene Delivery in Cancer Therapy. Olsztynska, S., & Komorowska, M. (Eds.), BIOMEDICAL ENGINEERING, TRENDS, RESEARCH AND TECHNOLOGIES. (pp. 245-272). IntechOpen. conference paper Sharma, R., Venkatadri, R., Dogan, M., Palakurthi, S., Mohammad, S., Hudspeth, A., & Palakurthi, S (2020). Cationic Cyclodextrins Regulate Nucleic Acid-induced Proinflammatory Responses. Journal of Immunology. Palakurthi, S., & Yellepeddi, V. K (2014). NANO POLYMER-CISPLATIN COMPLEXES FOR CHEMOTHERAPY OF OVARIAN CANCER. Anticancer Research: international journal of cancer research and treatment. 6095-6095. Liu, J. L., Hernandez, E., Okakpu, U., Palakurthi, S., & Bashir, S (2014). Cytotoxicity evaluation of nanomaterials derived from green synthesis. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Hernandez, E., Posa, S. R., Du, X., Palakurthi, S., Liu, J., & Bashir, S (2014). Evaluation of design and magnetism of nanoparticles and their in vitro cytotoxicity analyses. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Martinez, B., Maganti, M., Palakurthi, S., Liu, J., & Bashir, S (2014). Functionalized metal-organic frameworks as inhibitor of cell division. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Wei, Z., Martinez, B., Zhou, H., Palakurthi, S., Bashir, S., & Liu, J. (2014). Investigation of nanostructured metal-organic frameworks used in cancer research. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Yellepeddi, V. K., Kumar, A., & Palakurthi, S (2008). BIOTINYLATED CISPLATIN-LOADED PAMAM DENDRIMERS FOR CHEMOTHERAPY OF OVARIAN CANCER. Anticancer Research: international journal of cancer research and treatment. 3432-3433.
principal investigator on Dissolution Methods for Topical Ocular Emulsions awarded by United States Food and Drug Administration - (Silver Spring, Maryland, United States) 2014 - 2017
investigator on Dissolution of Smokeless Tobacco Products awarded by United States Food and Drug Administration - (Silver Spring, Maryland, United States) 2018 - 2020
teaching activities PHAR741 Pharmaceutics Ii Instructor PHAR785 Independent Study Instructor PHSC611 Drug Delvery & Formulations Instructor PHSC685 Directed Studies Instructor PHSC689 Sptp: Transderm & Topic Drug Instructor PHSC691 Research Instructor
education and training Ph.D. in Pharmaceutics, Indian Institute of Chemical Technology - (Hyderabad, India) 2000 Pharm.M. in Pharmaceutics, Dr. Hari Singh Gour University - (Saugor, Madhya Pradesh, India) 1993 B.Pharm., Kakatiya University - (Warangal, India) 1991
awards and honors Enhancing Development and Generating Excellence in Scholarship (EDGES) Fellow, conferred by Texas A&M University - (College Station, Texas, United States), 2024