selected publications academic article Srivatsa Palakurthi, S., Bharat Charbe, N., Recalde Phillips, S. Y., Alge, D. L., Lu, D., & Palakurthi, S. (2023). Development of optimal in vitro release and permeation testing method for rectal suppositories. 640, 123042-123042. Charbe, N. B., Tambuwala, M., Palakurthi, S. S., Warokar, A., Hromi-Jahjefendi, A., Bakshi, H., ... Palakurthi, S. (2023). Biomedical applications of three-dimensional bioprinted craniofacial tissue engineering. Bioengineering & Translational Medicine. 8(1), e10333. Renukuntla, J., Palakurthi, S. S., Bolla, P. K., Clark, B. A., Boddu, S., Manda, P., ... Palakurthi, S. (2022). Advances in in-vitro bioequivalence testing methods for complex ophthalmic generic products. International Journal of Pharmaceutics. 627, 122209-122209. Venkata, P. P., Chen, Y., Alejo, S., He, Y. i., Palacios, B. E., Loeffel, I., ... Sareddy, G. R. (2022). KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer. Cancer Letters. 524, 219-231. Khare, T., Palakurthi, S. S., Shah, B. M., Palakurthi, S., & Khare, S. (2020). Natural Product-Based Nanomedicine in Treatment of Inflammatory Bowel Disease. International Journal of Molecular Sciences. 21(11), 3956-3956. Shah, B. M., Palakurthi, S. S., Khare, T., Khare, S., & Palakurthi, S. (2020). Natural proteins and polysaccharides in the development of micro/nano delivery systems for the treatment of inflammatory bowel disease. International Journal of Biological Macromolecules. 165(Pt A), 722-737. Vaidya, B., Shukla, S. K., Kolluru, S., Huen, M., Mulla, N., Mehra, N., ... Gupta, V. (2019). Nintedanib-cyclodextrin complex to improve bio-activity and intestinal permeability. Carbohydrate Polymers. 204, 68-77. Mehra, N. K., Tekmal, R. R., & Palakurthi, S. (2018). Development and Evaluation of Talazoparib Nanoemulsion for Systemic Therapy of BRCA1-mutant Cancer. Anticancer Research: international journal of cancer research and treatment. 38(8), 4493-4503. Hidau, M. K., Kolluru, S., & Palakurthi, S. (2018). Development and validation of a high-performance liquid chromatography method for the quantification of talazoparib in rat plasma: Application to plasma protein binding studies. Biomedical Chromatography. 32(2), e4046-e4046. Palakurthi, S., Kolluru, S., Mehra, N., & Hidau, M. (2017). Cyclodextrin Complexation of Meclizine Hydrochloride and its Influence on the Solubility for its Repurposing. Drug Delivery Letters. 7(1), 54-61. Wei, Z., Maganti, M., Martinez, B., Vangara, K. K., Palakurthi, S., Luo, Z., ... Liu, J. (2016). Biological study of metal-organic frameworks towards human ovarian cancer cell lines. Canadian Journal of Chemistry. 94(4), 380-385. Mehra, N. K., & Palakurthi, S. (2016). Interactions between carbon nanotubes and bioactives: a drug delivery perspective. Drug Discovery Today. 21(4), 585-597. Yellepeddi, V. K., & Palakurthi, S. (2016). Recent Advances in Topical Ocular Drug Delivery. Journal of Ocular Pharmacology and Therapeutics. 32(2), 67-82. Mehra, N. K., Cai, D., Kuo, L., Hein, T., & Palakurthi, S. (2016). Safety and toxicity of nanomaterials for ocular drug delivery applications. Nanotoxicology. 10(7), 836-860. Palakurthi, S. (2015). Challenges in SN38 drug delivery: current success and future directions. Expert Opinion on Drug Delivery. 12(12), 1911-1921. Vangara, K. K., Ali, H. I., Lu, D., Liu, J. L., Kolluru, S., & Palakurthi, S. (2014). SN-38-cyclodextrin complexation and its influence on the solubility, stability, and in vitro anticancer activity against ovarian cancer. AAPS PharmSciTech. 15(2), 472-482. Paliwal, R., Babu, R. J., & Palakurthi, S. (2014). Nanomedicine scale-up technologies: feasibilities and challenges. AAPS PharmSciTech. 15(6), 1527-1534. Mishra, M. N., Vangara, K. K., & Palakurthi, S. (2014). Transcriptional targeting of human liver carboxylesterase (hCE1m6) and simultaneous expression of anti-BCRP shRNA enhances sensitivity of breast cancer cells to CPT-11. Anticancer Research: international journal of cancer research and treatment. 34(11), 6345-6351. Paliwal, R., & Palakurthi, S. (2014). Zein in controlled drug delivery and tissue engineering. Journal of Controlled Release. 189, 108-122. Yellepeddi, V. K., Vangara, K. K., & Palakurthi, S. (2013). Poly(amido)amine (PAMAM) dendrimer-cisplatin complexes for chemotherapy of cisplatin-resistant ovarian cancer cells. Journal of Nanoparticle Research. 15(9), 1897. Vangara, K. K., Liu, J. L., & Palakurthi, S. (2013). Hyaluronic acid-decorated PLGA-PEG nanoparticles for targeted delivery of SN-38 to ovarian cancer. Anticancer Research: international journal of cancer research and treatment. 33(6), 2425-2434. Kumar, A., & Palakurthi, S. (2013). P53 Gene Therapy Sensitizes Resistant Breast Cancer Cells to Doxorubicin Chemotherapy. Drug Delivery Letters. 3(3), 165-174. Yellepeddi, V. K., & Vangara, K. K. (2013). In vivo Efficacy of PAMAM-Dendrimer-Cisplatin Complexes in SKOV-3 Xenografted Balb/C Nude Mice. Journal of Biotechnology and Biomaterials. 2013. Sethi, R., Manchanda, S., Perepu, R., Kumar, A., Garcia, C., Kennedy, R. H., Palakurthi, S., & Dostal, D. (2012). Differential expression of caveolin-1 and caveolin-3: potential marker for cardiac toxicity subsequent to chronic ozone inhalation. MOLECULAR AND CELLULAR BIOCHEMISTRY. 369(1-2), 9-15. Yellepeddi, V. K., Vangara, K. K., Kumar, A., & Palakurthi, S. (2012). Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells. Anticancer Research: international journal of cancer research and treatment. 32(9), 3651-3658. Palakurthi, S., Yellepeddi, V. K., & Vangara, K. K. (2012). Recent trends in cancer drug resistance reversal strategies using nanoparticles. Expert Opinion on Drug Delivery. 9(3), 287-301. Kumar, A., Yellepeddi, V. K., Vangara, K. K., Strychar, K. B., & Palakurthi, S. (2011). Mechanism of gene transfection by polyamidoamine (PAMAM) dendrimers modified with ornithine residues. 19(9), 770-780. Yellepeddi, V. K., Kumar, A., Maher, D. M., Chauhan, S. C., Vangara, K. K., & Palakurthi, S. (2011). Biotinylated PAMAM dendrimers for intracellular delivery of cisplatin to ovarian cancer: role of SMVT. Anticancer Research: international journal of cancer research and treatment. 31(3), 897-906. Kumar, A., Yellepeddi, V. K., Davies, G. E., Strychar, K. B., & Palakurthi, S. (2010). Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues. International Journal of Pharmaceutics. 392(1-2), 294-303. Yellepeddi, V. K., Kumar, A., & Palakurthi, S (2009). Biotinylated poly(amido)amine (PAMAM) dendrimers as carriers for drug delivery to ovarian cancer cells in vitro. Anticancer Research: international journal of cancer research and treatment. 29(8), 2933-2943. Zhao, Y., Seefeldt, T., Chen, W., Carlson, L., Stoebner, A., Hanson, S., ... Guan, X. (2009). Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation. Free Radical Biology and Medicine. 47(2), 176-183. Yellepeddi, V. K., Kumar, A., & Palakurthi, S. (2009). Surface modified poly(amido)amine dendrimers as diverse nanomolecules for biomedical applications. Expert Opinion on Drug Delivery. 6(8), 835-850. Palakurthi, S., Wilson, J., McQuarrie, S. A., Suresh, M. R., Mercer, J. R., & Miller, G. G. (2008). Target specificity of 188Re-labeled B27.1 monoclonal antibodies to ovarian cancer cells in vivo. In Vivo: international journal of experimental and clinical pathophysiology and drug research. 22(3), 321-326. Pisal, D. S., Yellepeddi, V. K., Kumar, A., Kaushik, R. S., Hildreth, M. B., Guan, X., & Palakurthi, S. (2008). Permeability of surface-modified polyamidoamine (PAMAM) dendrimers across Caco-2 cell monolayers. International Journal of Pharmaceutics. 350(1-2), 113-121. Pisal, D. S., Yellepeddi, V. K., Kumar, A., & Palakurthi, S. (2008). Transport of surface engineered polyamidoamine (PAMAM) dendrimers across IPEC-J2 cell monolayers. Drug Delivery. 15(8), 515-522. Palakurthi, S., Mcquarrie, S. A., & Suresh, M. R. (2007). Screening of 14C-polyamines in the AT3B-1 rat prostate tumor model: the search for a new PET prostate imaging agent. In Vivo: international journal of experimental and clinical pathophysiology and drug research. 21(5), 823-828. Palakurthi, S., Vyas, S. P., & Diwan, P. V. (2005). Biodisposition of PEG-coated lipid microspheres of indomethacin in arthritic rats. International Journal of Pharmaceutics. 290(1-2), 55-62. Srinath, P., Rao, P. N., Knaus, E. E., & Suresh, M. R. (2003). Effect of cyclooxygenase-2 (COX-2) inhibitors on prostate cancer cell proliferation. 23(5A), 3923-3928. Srinath, P., McQuarrie, S. A., & Suresh, M. R. (2002). Comparative uptake of polyamines by prostate and non-prostate cancer cell lines. Nuclear Medicine and Biology. 29(4), 497-503. Palakurthi, S., Govardhanachary, M., Vyas, S. P., & Diwan, P. V. (2000). Biodistribution of liposomes of terbutaline sulfate in guinea pigs. 26(10), 1099-1105. Srinath, P., Chary, M. G., Vyas, S. P., & Diwan, P. V. (2000). Long-circulating liposomes of indomethacin in arthritic rats--a biodisposition study. Pharmaceutica acta Helvetiae. 74(4), 399-404. Srinath, P., Vyas, S. P., & Diwan, P. V. (2000). Preparation and pharmacodynamic evaluation of liposomes of indomethacin. 26(3), 313-321. SRINATH, P., VYAS, S. P., & DIWAN, P. V. (1999). Effect of Lipid Composition of Liposomes on Biodisposition of Indomethacin in Arthritic Rats. Journal of Pharmacy and Pharmacology. 5(5), 339-344. Srinath, P., & Diwan, P. V. (1998). Pharmacodynamic and pharmacokinetic evaluation of lipid microspheres of indomethacin. Pharmaceutica acta Helvetiae. 73(4), 199-203. Palakurthi, S. S., Shah, B., Kapre, S., Charbe, N., Immanuel, S., Pasham, S., ... Palakurthi, S. A comprehensive review of challenges and advances in exosome-based drug delivery systems. NANOSCALE ADVANCES. book Bashir, S., Palakurthi, S., Zhou, H. C., & Liu, J. (2014). Nanometals and complexes in cancer diagnosis and therapy Bashir, S., Palakurthi, S., Zhou, H. C., & Liu, J. Handbook of Metallonutraceuticals. CRC Press. chapter Bashir, S., Chava, S. R., Yuan, D., Palakurthi, S., & Liu, J. (2020). Metal-organic frameworks and exemplified cytotoxicity evaluation. METAL-ORGANIC FRAMEWORKS FOR BIOMEDICAL APPLICATIONS. (pp. 347-381). Elsevier. Palakurthi, S., Yellepeddi, V. K., & Kumar, A. (2011). Nanocarriers for Cytosolic Drug and Gene Delivery in Cancer Therapy. Olsztynska, S., & Komorowska, M. (Eds.), BIOMEDICAL ENGINEERING, TRENDS, RESEARCH AND TECHNOLOGIES. (pp. 245-272). IntechOpen. conference paper Sharma, R., Venkatadri, R., Dogan, M., Palakurthi, S., Mohammad, S., Hudspeth, A., & Palakurthi, S (2020). Cationic Cyclodextrins Regulate Nucleic Acid-induced Proinflammatory Responses. Journal of Immunology. Palakurthi, S., & Yellepeddi, V. K (2014). NANO POLYMER-CISPLATIN COMPLEXES FOR CHEMOTHERAPY OF OVARIAN CANCER. Anticancer Research: international journal of cancer research and treatment. 6095-6095. Liu, J. L., Hernandez, E., Okakpu, U., Palakurthi, S., & Bashir, S (2014). Cytotoxicity evaluation of nanomaterials derived from green synthesis. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Hernandez, E., Posa, S. R., Du, X., Palakurthi, S., Liu, J., & Bashir, S (2014). Evaluation of design and magnetism of nanoparticles and their in vitro cytotoxicity analyses. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Martinez, B., Maganti, M., Palakurthi, S., Liu, J., & Bashir, S (2014). Functionalized metal-organic frameworks as inhibitor of cell division. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Wei, Z., Martinez, B., Zhou, H., Palakurthi, S., Bashir, S., & Liu, J. (2014). Investigation of nanostructured metal-organic frameworks used in cancer research. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. Yellepeddi, V. K., Kumar, A., & Palakurthi, S (2008). BIOTINYLATED CISPLATIN-LOADED PAMAM DENDRIMERS FOR CHEMOTHERAPY OF OVARIAN CANCER. Anticancer Research: international journal of cancer research and treatment. 3432-3433.
principal investigator on Dissolution Methods for Topical Ocular Emulsions awarded by United States Food and Drug Administration - (Silver Spring, Maryland, United States) 2014 - 2017
investigator on Dissolution of Smokeless Tobacco Products awarded by United States Food and Drug Administration - (Silver Spring, Maryland, United States) 2018 - 2020
teaching activities PHAR741 Pharmaceutics Ii Instructor PHAR785 Independent Study Instructor PHSC611 Drug Delvery & Formulations Instructor PHSC685 Directed Studies Instructor PHSC689 Sptp: Transderm & Topic Drug Instructor PHSC691 Research Instructor
education and training Ph.D. in Pharmaceutics, Indian Institute of Chemical Technology - (Hyderabad, India) 2000 Pharm.M. in Pharmaceutics, Dr. Hari Singh Gour University - (Saugor, Madhya Pradesh, India) 1993 B.Pharm., Kakatiya University - (Warangal, India) 1991
awards and honors Enhancing Development and Generating Excellence in Scholarship (EDGES) Fellow, conferred by Texas A&M University - (College Station, Texas, United States), 2024