selected publications academic article Gibbs, H. C., Mota, S. M., Hart, N. A., Min, S. W., Vernino, A. O., Pritchard, A. L., ... Perez, L. M. (2021). Navigating the Light-Sheet Image Analysis Software Landscape: Concepts for Driving Cohesion From Data Acquisition to Analysis. Frontiers in Cell and Developmental Biology. 9, 739079. Chaudhari, P., Ade, N., Pérez, L. M., Kolis, S., & Mashuga, C. V. (2021). Minimum Ignition Energy (MIE) prediction models for ignition sensitive fuels using machine learning methods. JOURNAL OF LOSS PREVENTION IN THE PROCESS INDUSTRIES. 69, 104343-104343. Grajales, J. A., Pérez, L. M., Schwab, A. P., & Little, D. N. (2021). Quantum Chemical Modeling of the Effects of Hydrated Lime (Calcium Hydroxide) as a Filler in Bituminous Materials. ACS Omega. 6(4), 3130-3139. Ravi, A., Foster, E. R., Perez, L. M., & Nikolov, Z. L. (2020). Capture chromatography with mixed-mode resins: A case study with recombinant human thioredoxin from Escherichia coli. J CHROMATOGR. 1625, 461327-461327. Chaudhari, P., Ade, N., Pérez, L. M., Kolis, S., & Mashuga, C. V. (2020). Quantitative Structure-Property Relationship (QSPR) models for Minimum Ignition Energy (MIE) prediction of combustible dusts using machine learning. Powder Technology. 372, 227-234. Tharp, J. M., Hampton, J. T., Reed, C. A., Ehnbom, A., Chen, P., Morse, J. S., ... Liu, W. R. (2020). An amber obligate active site-directed ligand evolution technique for phage display. NATURE COMMUNICATIONS. 11(1), 1392. Le, T., Nguyen, H., Perez, L. M., Darensbourg, D. J., & Darensbourg, M. Y. (2020). Metal-Templated, Tight Loop Conformation of a Cys-X-Cys Biomimetic Assembles a Dimanganese Complex. Angew Chem Int Ed Engl. 59(9), 3645-3649. Sun, Q., Li, X., Perez, L. M., Shi, W., Zhang, Y., & Sacchettini, J. C. (2020). The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. NATURE COMMUNICATIONS. 11(1), 339. Schuckman, A. E., Ewers, B. W., Yu, L. H., Tom, J., Prez, L. M., Drain, C. M., Kushmerick, J. G., & Batteas, J. D. (2015). Utilizing Nearest-Neighbor Interactions To Alter Charge Transport Mechanisms in Molecular Assemblies of Porphyrins on Surfaces. J Phys Chem C Nanomater Interfaces. Xin, D., Perez, L. M., Ioerger, T. R., & Burgess, K. (2014). A multifaceted secondary structure mimic based on piperidine-piperidinones. Angew Chem Int Ed Engl. 53(14), 3594-3598. Powers, D. C., Anderson, B. L., Hwang, S. J., Powers, T. M., Prez, L. M., Hall, M. B., ... Nocera, D. G. (2014). Photocrystallographic observation of halide-bridged intermediates in halogen photoeliminations. Journal of the American Chemical Society. 136(43), 15346. Xin, D., Ko, E., Perez, L. M., Ioerger, T. R., & Burgess, K. (2013). Evaluating minimalist mimics by exploring key orientations on secondary structures (EKOS). Org Biomol Chem. 11(44), 7789-7801. DeBord, J. D., Verkhoturov, S. V., Perez, L. M., North, S. W., Hall, M. B., & Schweikert, E. A. (2013). Measuring the internal energies of species emitted from hypervelocity nanoprojectile impacts on surfaces using recalibrated benzylpyridinium probe ions. J Chem Phys. 138(21), 214301-214301. Ko, E., Raghuraman, A., Perez, L. M., Ioerger, T. R., & Burgess, K. (2013). Exploring key orientations at protein-protein interfaces with small molecule probes. Journal of the American Chemical Society. 135(1), 167-173. Salembier, H., Mauldin, J., Hammond, T., Wallace, R., Alqassab, E., Hall, M. B., ... Chin, R. M (2012). Diruthenium Naphthalene and Anthracene Complexes Containing a Doubly Linked Dicyclopentadienyl Ligand. Organometallics. 31(13), 4838-4848. Renz, A. L., Pérez, L. M., & Hall, M. B. (2011). Carbon–Bromine Bond Formation through a Nickel-Centered Spin-Crossing Mechanism. Organometallics. 30(23), 6365-6371. Ko, E., Liu, J., Perez, L. M., Lu, G., Schaefer, A., & Burgess, K (2011). Universal peptidomimetics. Journal of the American Chemical Society. 133(3), 462-477. Karadas, F., Shatruk, M., Perez, L. M., & Dunbar, K. R. (2010). Cyanide-bridged [Co(II)2M(II)] and [Co(II)2M(II)2] complexes based on the [Co(II)(triphos)(CN)2] building block: syntheses, structures, magnetic properties, and density functional theoretical studies. Chemistry – A European Journal. 16(24), 7164-7173. Mintzer, M. A., Perez, L. M., & Simanek, E. E (2010). Divergent synthesis of triazine dendrimers using a trimethylene-dipiperidine linker that increases efficiency, simplifies analysis, and improves product solubility. Tetrahedron Lett. 51(13), 1631-1634. Lim, J., Mintzer, M. A., Perez, L. M., & Simanek, E. E (2010). Synthesis of odd generation triazine dendrimers using a divergent, macromonomer approach. ORGANIC LETTERS. 12(6), 1148-1151. Chiarella, G. M., Melgarejo, D. Y., Rozanski, A., Hempte, P., Perez, L. M., Reber, C., & Fackler, J. P (2010). A short, unsupported CuI...CuI interaction, 2.65 A, in a dinuclear guanidine chloride complex. Chemical Communications. 46(1), 136-138. Lalwani, S., Chouai, A., Perez, L. M., Santiago, V., Shaunak, S., & Simanek, E. E (2009). Mimicking PAMAM Dendrimers with Ampholytic, Hybrid Triazine Dendrimers: A Comparison of Dispersity and Stability. MACROMOLECULES. 42(17), 6723-3732. Wu, Z., Fernandez-Lima, F. A., Perez, L. M., & Russell, D. H. (2009). A new copper containing MALDI matrix that yields high abundances of [peptide + Cu]+ ions. Journal of the American Society for Mass Spectrometry. 20(7), 1263-1271. Bench, B. J., Tichy, S. E., Perez, L. M., Benson, J., & Watanabe, C (2008). Synthesis and cellular effects of cycloterpenals: cyclohexadienal-based activators of neurite outgrowth. Bioorganic & Medicinal Chemistry. 16(16), 7573-7581. Crampton, H., Hollink, E., Perez, L. M., & Simanek, E. E (2007). A divergent route towards single-chemical entity triazine dendrimers with opportunities for structural diversity. NEW JOURNAL OF CHEMISTRY. 31(7), 1283-1290. Kim, Y., Manalo, M. N., Peréz, L. M., & LiWang, A. (2006). Computational and empirical trans-hydrogen bond deuterium isotope shifts suggest that N1-N3 A:U hydrogen bonds of RNA are shorter than those of A:T hydrogen bonds of DNA. J Biomol NMR. 34(4), 229-236. Mohamed, A. A., Pérez, L. M., & Fackler, J. P. (2005). Unsupported intermolecular argentophilic interaction in the dimer of trinuclear silver(I) 3,5-diphenylpyrazolates. Inorganica Chimica Acta. 358(5), 1657-1662. Szalay, P. S., Galn-Mascars, J. R., Schottel, B. L., Bacsa, J., Prez, L. M., Ichimura, A. S., Chouai, A., & Dunbar, K. R. (2004). Experimental and Computational Studies of Charge-Transfer and Reduction Products of 1, 4, 5, 8, 9, 11-Hexaazatriphenylene-Hexacarbonitrile: HAT-(CN)6. Journal of Cluster Science: including nanoclusters and nanoparticles. 15(4), 503-530. Darensbourg, D. J., Billodeaux, D. R., & Perez, L. M. (2004). 113Cd NMR Determination of the Binding Parameters of Alicyclic Epoxides to [Hydrotris(3-phenylpyrazol-1-yl)borate]Cd(II) Acetate. Organometallics. 23(22), 5286-5290. Wang, H., Webster, C. E., Prez, L. M., Hall, M. B., & Gabba, F. P. (2004). Reaction of the 1,8-bis(diphenylmethylium)naphthalenediyl dication with fluoride: formation of a cation containing a C-F-->C bridge. Journal of the American Chemical Society. 126(26), 8189-8196. (2004). HAT-(CN) 6. 15(4), Peterson, K. A., Li, Y., Francisco, J. S., Zou, P., Webster, C. E., Prez, L. M., Hall, M. B., & North, S. W. (2003). The role of triplet states in the long wavelength absorption region of bromine nitrate. J Chem Phys. 119(15), 7864-7870. Zhang, W., Jiang, J., Qin, C., Prez, L. M., Parrish, A. R., Safe, S. H., & Simanek, E. E. (2003). Triazine Dendrimers for Drug Delivery: Evaluation of Solubilization Properties, Activity in Cell Culture, and In Vivo Toxicity of a Candidate Vehicle. Supramolecular Chemistry. 15(7-8), 607-616. Chifotides, H. T., Koshlap, K. M., Prez, L. M., & Dunbar, K. R. (2003). Novel binding interactions of the DNA fragment d(pGpG) cross-linked by the antitumor active compound tetrakis(mu-carboxylato)dirhodium(II,II). Journal of the American Chemical Society. 125(35), 10714-10724. Chifotides, H. T., Koshlap, K. M., Prez, L. M., & Dunbar, K. R. (2003). Unprecedented head-to-head conformers of d(GpG) bound to the antitumor active compound tetrakis (mu-carboxylato)dirhodium(II,II). Journal of the American Chemical Society. 125(35), 10703-10713. Cotton, F. A., Donahue, J. P., Murillo, C. A., Pérez, L. M., & Yu, R. (2003). Cyclic polyamidato dianions as bridges between Mo(2)(4+) units: synthesis, crystal structures, electrochemistry, absorption spectra, and electronic structures. Journal of the American Chemical Society. 125(29), 8900-8910. Cotton, F. A., Donahue, J. P., Murillo, C. A., & Pérez, L. M. (2003). Polyunsaturated dicarboxylate tethers connecting dimolybdenum redox and chromophoric centers: absorption spectra and electronic structures. Journal of the American Chemical Society. 125(18), 5486-5492. Zhang, W., Tichy, S. E., Prez, L. M., Maria, G. C., Lindahl, P. A., & Simanek, E. E. (2003). Evaluation of multivalent dendrimers based on melamine: kinetics of thiol-disulfide exchange depends on the structure of the dendrimer. Journal of the American Chemical Society. 125(17), 5086-5094. Meloni, G., Thomson, L. M., & Gingerich, K. A (2001). Structure and thermodynamic stability of the OsC and OsC2 molecules by theoretical calculations and by Knudsen cell mass spectrometry. J Chem Phys. 115(10), 4496-4501. conference paper Jr, F., Abdou, H., Mohamed, A. A., Burini, A., Galassi, R., & Perez, L. M (2006). New chemistry with an old element: Gold with nitrogen ligands. ACS National Meeting Book of Abstracts. Schottel, B. L., Chifotides, H., Shatruk, M., Bacsa, J., Perez, L. M., Chouai, A., & Dunbar, K. R. (2005). Anion-n interactions as controlling elements in supramolecular chemistry. ACS National Meeting Book of Abstracts. U3143-U3145. Kail, B. W., Perez, L. M., Zaric, S. D., Millar, A., Young, C. G., Hall, M. B., & Basu, P (2005). Mechanistic investigation of the oxygen atom transfer reactivity of dioxo-molybdenum(VI) complexes. ACS National Meeting Book of Abstracts. U2077-U2077. Beckley, J. R., Perez, L. M., Scholtz, J. M., Pace, C. N., & Russell, D. H. (2005). Secondary structure of gas-phase model alanine-containing peptide ions in a low dielectric environment. Biophysical Journal. 42A-42A.
co-principal investigator on Cellulose Nanocrystal-Enabled Manufacturing of Carbon Nanotube/Carbon Fiber Polymer Composites awarded by National Science Foundation - (Arlington, Virginia, United States) 2019 - 2022 Cyber Training : CIC: The Texas A&M University Computational Materials Science Summer School (CMS3) awarded by National Science Foundation - (Arlington, Virginia, United States) 2018 - 2021
teaching activities CHEM491 Hnr-research Instructor CHEM658 Molecular Modeling Instructor CHEM685 Directed Studies Instructor
education and training Ph.D. in Physical Chemistry, Texas A&M University - (College Station, Texas, United States) 2002 B.S. in Chemistry, minor in Mathematics and Computer Information Systems, Humboldt State University - (Arcata, California, United States) 1994
mailing address Texas A&M University High Performance Research Computing 3361 TAMU College Station, TX 77843-3361 USA
In the News Paving the way for new peptide-based therapeutics with novel method of phage display News Release