HR job title
- Assistant Professor
- Contact Info
- Websites
- ORCiD
- 0000-0003-4926-5467
Mabbott, Samuel Assistant Professor
Positions
- Assistant Professor, Biomedical Engineering, College of Engineering
Dr. Mabbott's research focuses on the development of metallic nanoparticles for use in biomedical devices and healthcare settings. Applications include: integration into point of care devices for sensitive detection of disease relevant biomolecules such as circulating miRNA; controlling the nanoparticles light-to-heat conversion (photothermal) efficiency for destruction of diseased tissues (eg. Tumors); localized delivery of miRNA for gene therapy; increasing the therapeutic effect of drugs; biological and chemical signal amplification.
Research Areas
- Overview
- Publications
- Teaching
- Background
- Contact
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Overview
Publications
selected publications
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academic article
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Chavva, S. R., San Juan, A., Jaitpal, S., Vu, N. N., & Mabbott, S.
(2024).
Efficient production of uniform gold nanoparticles via a streamlined low-cost, semi-automated, open-source platform. Nanoscale.
-
San Juan, A. M., Jaitpal, S., Ng, K. W., Martinez, C., Tripathy, S., Phillips, C., Cot, G. L., & Mabbott, S.
(2024).
Freeze-Driven Synthesis of DNA Hairpin-Conjugated Gold Nanoparticle Biosensors for Dual-Mode Detection. ACS Applied Bio Materials.
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Tripathy, S., Chavva, S., Cote, G. L., & Mabbott, S.
(2023).
Modular and handheld Raman systems for SERS-based point-of-care diagnostics. 28, 100488-100488.
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Soliman, C., Faircloth, J., Tu, D., Mabbott, S., Maitland, K., & Cot, G.
(2023).
Exploring the Clinical Utility of Raman Spectroscopy for Point-of-Care Cardiovascular Disease Biomarker Detection. 77(10), 1181-1193.
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Clevenger, A. J., Crawford, L. Z., Noltensmeyer, D., Babaei, H., Mabbott, S. B., Avazmohammadi, R., & Raghavan, S.
(2023).
Rapid Prototypable Biomimetic Peristalsis Bioreactor Capable of Concurrent Shear and Multi-Axial Strain. Cells, Tissues, Organs: in vivo, in vitro.
212(1), 96-110.
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Soliman, C., Tu, D., Mabbott, S., Cot, G., & Maitland, K.
(2022).
Portable, multi-modal Raman and fluorescence spectroscopic platform for point-of-care applications. Journal of Biomedical Optics.
27(9), 095006-095006.
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Chavva, S. R., Bhat, N., San Juan, A., Jaitpal, S., & Mabbott, S.
(2022).
Simultaneous Thermal and Spectroscopic Screening of Morphologically Complex Theranostic Gold Nanoparticles. 3(2), 102-116.
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Tu, D., Holderby, A., Guo, H., Mabbott, S., Tian, L., & Cot, G. L.
(2022).
Spectrally multiplexed assay using gap enhanced nanoparticle for detection of a myocardial infarction biomarker panel. Analytica Chimica Acta.
1198, 339562-339562.
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Jaitpal, S., Chavva, S. R., & Mabbott, S.
(2022).
3D Printed SERS-Active Thin-Film Substrates Used to Quantify Levels of the Genotoxic Isothiazolinone. ACS Omega.
7(3), 2850-2860.
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San Juan, A., Chavva, S. R., Tu, D., Tircuit, M., Cot, G., & Mabbott, S.
(2021).
Synthesis of SERS-active core-satellite nanoparticles using heterobifunctional PEG linkers. NANOSCALE ADVANCES.
4(1), 258-267.
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Tu, D., Holderby, A., Dean, J., Mabbott, S., & Cot, G. L.
(2021).
Paper Microfluidic Device with a Horizontal Motion Valve and a Localized Delay for Automatic Control of a Multistep Assay. Analytical Chemistry.
93(10), 4497-4505.
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Girard, A., Cooper, A., Mabbott, S., Bradley, B., Asiala, S., Jamieson, L., ... Graham, D.
(2021).
Raman spectroscopic analysis of skin as a diagnostic tool for Human African Trypanosomiasis. PLOS Pathogens.
17(11), e1010060-e1010060.
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Mabbott, S., Fernandes, S. C., Schechinger, M., Cote, G. L., Faulds, K., Mace, C. R., & Graham, D.
(2020).
Detection of cardiovascular disease associated miR-29a using paper-based microfluidics and surface enhanced Raman scattering. The Analyst.
145(3), 983-991.
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Schechinger, M., Marks, H., Mabbott, S., Choudhury, M., & Cote', G.
(2019).
A SERS approach for rapid detection of microRNA-17 in the picomolar range. The Analyst.
144(13), 4033-4044.
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McConnell, G., Mabbott, S., Kanibolotsky, A. L., Skabara, P. J., Graham, D., Burley, G. A., & Laurand, N
(2018).
Organic Semiconductor Laser Platform for the Detection of DNA by AgNP Plasmonic Enhancement. Langmuir.
34(49), 14766-14773.
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Nicolson, F., Jamieson, L. E., Mabbott, S., Plakas, K., Shand, N. C., Detty, M. R., Graham, D., & Faulds, K
(2018).
Surface enhanced resonance Raman spectroscopy (SERRS) for probing through plastic and tissue barriers using a handheld spectrometer. The Analyst.
143(24), 5965-5973.
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Nicolson, F., Jamieson, L. E., Mabbott, S., Plakas, K., Shand, N. C., Detty, M. R., Graham, D., & Faulds, K
(2018).
Towards establishing a minimal nanoparticle concentration for applications involving surface enhanced spatially offset resonance Raman spectroscopy (SESORRS) in vivo. The Analyst.
143(22), 5358-5363.
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Nicolson, F., Jamieson, L. E., Mabbott, S., Plakas, K., Shand, N. C., Detty, M. R., Graham, D., & Faulds, K
(2018).
Multiplex imaging of live breast cancer tumour models through tissue using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS). Chemical Communications.
54(61), 8530-8533.
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Nicolson, F., Jamieson, L. E., Mabbott, S., Plakas, K., Shand, N. C., Detty, M. R., Graham, D., & Faulds, K
(2018).
Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS). Chemical Science.
9(15), 3788-3792.
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Pala, L., Mabbott, S., Faulds, K., Bedics, M. A., Detty, M. R., & Graham, D.
(2018).
Introducing 12 new dyes for use with oligonucleotide functionalised silver nanoparticles for DNA detection with SERS. RSC Advances.
8(32), 17685-17693.
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Nicolson, F., Jamieson, L. E., Mabbott, S., Shand, N. C., Graham, D., & Faulds, K.
(2017).
Through barrier detection of ethanol using handheld Raman spectroscopyConventional Raman versus spatially offset Raman spectroscopy (SORS). 48(12), 1828-1838.
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Mabbott, S., Xu, Y., & Goodacre, R.
(2017).
Objective assessment of SERS thin films: comparison of silver on copper via galvanic displacement with commercially available fabricated substrates. Analytical Methods.
9(33), 4783-4789.
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Laing, S., Suriano, R., Lamprou, D. A., Smith, C., Dalby, M. J., Mabbott, S., Faulds, K., & Graham, D
(2017).
Correction to Thermoresponsive Polymer Micropatterns Fabricated by Dip-Pen Nanolithography for a Highly Controllable Substrate with Potential Cellular Applications. ACS Applied Materials & Interfaces.
9(9), 8432-8432.
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Marks, H., Huang, P., Mabbott, S., Graham, D., Kameoka, J., & Cot, G.
(2016).
Ferric plasmonic nanoparticles, aptamers, and magnetofluidic chips: toward the development of diagnostic surface-enhanced Raman spectroscopy assays. Journal of Biomedical Optics.
21(12), 127005-127005.
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Mackanic, D. G., Mabbott, S., Faulds, K., & Graham, D.
(2016).
Analysis of Photothermal Release of Oligonucleotides from Hollow Gold Nanospheres by Surface-Enhanced Raman Scattering. Journal of Physical Chemistry C.
120(37), 20677-20683.
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Laing, S., Suriano, R., Lamprou, D. A., Smith, C., Dalby, M. J., Mabbott, S., Faulds, K., & Graham, D
(2016).
Thermoresponsive Polymer Micropatterns Fabricated by Dip-Pen Nanolithography for a Highly Controllable Substrate with Potential Cellular Applications. ACS Applied Materials & Interfaces.
8(37), 24844-24852.
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Mabbott, S., Thompson, D., Sirimuthu, N., McNay, G., Faulds, K., & Graham, D
(2016).
From synthetic DNA to PCR product: detection of fungal infections using SERS. Faraday Discussions.
187, 461-472.
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Docherty, J., Mabbott, S., Smith, E., Faulds, K., Davidson, C., Reglinski, J., & Graham, D.
(2016).
Detection of potentially toxic metals by SERS using salen complexes. The Analyst.
141(20), 5857-5863.
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Docherty, J., Mabbott, S., Smith, W. E., Reglinski, J., Faulds, K., Davidson, C., & Graham, D
(2015).
Determination of metal ion concentrations by SERS using 2,2'-bipyridyl complexes. The Analyst.
140(19), 6538-6543.
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Kashmery, H. A., Thompson, D. G., Dondi, R., Mabbott, S., Graham, D., Clark, A. W., & Burley, G. A
(2015).
SERS enhancement of silver nanoparticles prepared by a template-directed triazole ligand strategy. Chemical Communications.
51(65), 13028-13031.
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Bedics, M. A., Kearns, H., Cox, J. M., Mabbott, S., Ali, F., Shand, N. C., ... Detty, M. R
(2015).
Extreme red shifted SERS nanotags. Chemical Science.
6(4), 2302-2306.
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Mabbott, S., Alharbi, O., Groves, K., & Goodacre, R.
(2015).
Application of surface enhanced Raman scattering to the solution based detection of a popular legal high, 5,6-methylenedioxy-2-aminoindane (MDAI). The Analyst.
140(13), 4399-4406.
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Gracie, K., Correa, E., Mabbott, S., Dougan, J. A., Graham, D., Goodacre, R., & Faulds, K.
(2014).
Simultaneous detection and quantification of three bacterial meningitis pathogens by SERS. Chemical Science.
5(3), 1030-1040.
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Mabbott, S., Correa, E., Cowcher, D. P., Allwood, J. W., & Goodacre, R.
(2013).
Optimization of parameters for the quantitative surface-enhanced Raman scattering detection of mephedrone using a fractional factorial design and a portable Raman spectrometer. Analytical Chemistry.
85(2), 923-931.
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Mabbott, S., Eckmann, A., Casiraghi, C., & Goodacre, R
(2013).
2p or not 2p: tuppence-based SERS for the detection of illicit materials. The Analyst.
138(1), 118-122.
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Mabbott, S., Larmour, I. A., Vishnyakov, V., Xu, Y., Graham, D., & Goodacre, R.
(2012).
The optimisation of facile substrates for surface enhanced Raman scattering through galvanic replacement of silver onto copper. The Analyst.
137(12), 2791-2798.
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Ng, K. W., Chaturvedi, N., Cot, G. L., Fisher, S. A., & Mabbott, S.
Biomarkers and point of care screening approaches for the management of preeclampsia. 4(1), 208.
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Mabbott, S., Jaitpal, S., Ng, K. W., San Juan, A. M., Martinez, C., Phillips, C., & Tripathy, S.
DNA-Directed Formation of Plasmonic Core-Satellite Nanostructures for Quantification of Hepatitis C Viral RNA. Chemical Science.
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Chavva, S. R., San Juan, A., Jaitpal, S., Vu, N. N., & Mabbott, S.
(2024).
Efficient production of uniform gold nanoparticles via a streamlined low-cost, semi-automated, open-source platform. Nanoscale.
-
chapter
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Asiala, S., Barrett, L., Mabbott, S., & Graham, D.
(2016).
Advances in Biofunctional SERS-Active Nanoparticles for Future Clinical Diagnostics and Therapeutics. ACS Symposium Series.
FRONTIERS OF PLASMON ENHANCED SPECTROSCOPY, VOL 1.
(pp. 131-161).
American Chemical Society (ACS).
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Asiala, S., Barrett, L., Mabbott, S., & Graham, D.
(2016).
Advances in Biofunctional SERS-Active Nanoparticles for Future Clinical Diagnostics and Therapeutics. ACS Symposium Series.
FRONTIERS OF PLASMON ENHANCED SPECTROSCOPY, VOL 1.
(pp. 131-161).
American Chemical Society (ACS).
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conference paper
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Tripathy, S., Chavva, S. R., Juan, A., Cote, G. L., & Mabbott, S.
(2023).
Indirect sandwich aptamer assay coupled structurally stabilized hairpin assisted hybridization chain reaction for femtomolar detection of cardiac troponin I. 1-3.
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Chaturvedi, N., Kunkel, A., Schechinger, M., Mabbott, S., Choudhury, M., & Cote, G. L.
(2023).
Paper fluidic platform with dual-optical readouts to detect microRNA-20a (miR-20a) for preeclampsia. 123870g-123870g-8.
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Chaturvedi, N., Arias, R., Tu, D., Mabbott, S., & Cote, G. L.
(2022).
A low-cost, paper fluidic platform to detect B-type Natriuretic Peptide (BNP) for Congestive Heart Failure (CHF). Proceedings of SPIE.
1196805-1196805-7.
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Jaitpal, S., Chavva, S., & Mabbott, S.
(2021).
Towards point-of-care detection of microRNAs using paper-based microfluidics. Progress in Biomedical Optics and Imaging - Proceedings of SPIE.
116510c-116510c-6.
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Sengupta, S., Bedics, M., Plakas, K., Bromley, L., Kearns, H., Mabbott, S., ... Velarde, L
(2016).
Orientation and binding of near infrared absorbing dyes at a gold surface. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
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Heydari, E., Mabbott, S., Thompson, D., Graham, D., Cooper, J. M., & Clark, A. W.
(2016).
Engineering molecularly-active nanoplasmonic surfaces for DNA detection via colorimetry and Raman scattering. Proceedings of SPIE.
972105-972105-6.
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Marks, H., Mabbott, S., Huang, P., Jackson, G. W., Kameoka, J., Graham, D., & Cote, G. L.
(2016).
Comparison of Fe2O3 and Fe2CoO4 core-shell plasmonic nanoparticles for aptamer mediated SERS assays. 97220n-97220n-8.
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Hayes, M., Graham, D., & Mabbott, S
(2016).
Investigation of surface enhanced Raman scattering activity in silver-coated magnetic nanoparticles. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
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Hayes, M., Graham, D., & Mabbott, S
(2016).
Undergraduate research in Glasgow, Scotland: A study on magnetic nanoparticles and life beyond the United States. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
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Mackanic, D., Mabbott, S., & Graham, D
(2015).
Summer research in the UK: Unique chemistry in a unique environment. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
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Marks, H., Mabbott, S., Jackson, G. W., Graham, D., & Cote, G. L.
(2015).
SERS active colloidal nanoparticles for the detection of small blood biomarkers using aptamers. Proceedings of SPIE.
93381c-93381c-5.
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Tripathy, S., Chavva, S. R., Juan, A., Cote, G. L., & Mabbott, S.
(2023).
Indirect sandwich aptamer assay coupled structurally stabilized hairpin assisted hybridization chain reaction for femtomolar detection of cardiac troponin I. 1-3.
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institutional repository document
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Nicolson, F., Andreiuk, B., Lee, E., ODonnell, B., Whitley, A., Riepl, N., ... Haigis, K. M.
(2023).
In vivo Imaging using Surface Enhanced Spatially Offset Raman Spectroscopy (SESORS): Balancing Sampling Frequency to Improve Overall Image Acquisition
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Nicolson, F., Andreiuk, B., Lee, E., ODonnell, B., Whitley, A., Riepl, N., ... Haigis, K. M.
(2023).
In vivo Imaging using Surface Enhanced Spatially Offset Raman Spectroscopy (SESORS): Balancing Sampling Frequency to Improve Overall Image Acquisition
Teaching
teaching activities
- BMEN291 Hnr-research Instructor
- BMEN482 Polymeric Biomaterials Instructor
- BMEN483 Polymeric Biomatrl Synth Instructor
- BMEN491 Hnr-research Instructor
- BMEN491 Hnr-research Instructor
- BMEN682 Polymeric Biomaterials Instructor
- BMEN683 Polymeric Biomatrl Synth Instructor
- BMEN684 Professional Internship Instructor
- BMEN685 Directed Studies Instructor
- BMEN691 Research Instructor
Background
education and training
- Ph.D. in Biological Chemistry, University of Manchester - (Manchester, Manchester, United Kingdom) 2012
Contact
first name
- Samuel
has last name
- Mabbott
Other
- smabbott@tamu.edu