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Criscitiello, Michael Professor and Associate Dean for Research and Graduate Studies


My Comparative Immunogenetics Laboratory studies immunology, molecular genetics and evolution. Most of our group's research focuses on the natural history and future application of the vertebrate adaptive immune system, with particular attention given to the genetics of lymphocyte antigen receptors. Particular expertise lies in the evolution of vertebrate immunoglobulin loci, T cell receptor loci and the major histocompatibility complex. Additionally, we are interested in the evolution of diversification mechanisms at work there (e.g., recombination activating genes (RAG), activation-induced cytidine deaminase (AID), and the high allelic polymorphism maintained by classical MHC genes). Most recently, we have been working on lymphocyte development in shark thymus that suggests plasticity across the B lymphocyte/T lymphocyte divide, immunoglobulin heavy and light chain isotype pairing in an amphibian system, immunogenetics in marine mammals of conservation importance, mucosal humoral immunity in diverse tetrapods and cattle antibodies with an unheralded domain extending for novel antigen binding possibilities.

Research Areas research areas

HR job title

  • Associate Dean for Research and Graduate Studies