David Reiner - Texas A&M University (TAMU) Scholar

education and training

Ph.D. in Genetics, University of Washington - (Seattle, Washington, United States) 1996
B.A. in Biology, Carleton College - (Northfield, Minnesota, United States) 1988
University of North Carolina at Chapel Hill - (Chapel Hill, North Carolina, United States) , Postdoctoral Training 2004
University of California, Berkeley - (Berkeley, California, United States) , Postdoctoral Training 2002
University of Washington - (Seattle, Washington, United States) , Postdoctoral Training 1997

selected publications

academic article
- Duong, T., Rasmussen, N. R., Ballato, E., Mote, F. S., & Reiner, D. J. (2020). The Rheb-TORC1 signaling axis functions as a developmental checkpoint. DEVELOPMENT. dev.181727-dev.181727.
- Shin, H., Braendle, C., Monahan, K. B., Kaplan, R., Zand, T. P., Mote, F. S., Peters, E. C., & Reiner, D. J. (2019). Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals. PLOS GENETICS. 15(5), e1008056-e1008056.
- Shin, H., Kaplan, R., Duong, T., Fakieh, R., & Reiner, D. J. (2018). Ral Signals through a MAP4 Kinase-p38 MAP Kinase Cascade in C. elegans Cell Fate Patterning. CELL REPORTS.
- Rasmussen, N. R., Dickinson, D. J., & Reiner, D. J. (2018). Ras-Dependent Cell Fate Decisions Are Reinforced by the RAP-1 Small GTPase in Caenorhabditis elegans. GENETICS. 210(4), 1339-1354.
- Shin, H., & Reiner, D. J. (2018). The signaling network controlling C. elegans vulval cell fate patterning. Journal of Developmental Biology. 6(4), 30-30.
- Walck-Shannon, E., Lucas, B., Chin-Sang, I., Reiner, D., Kumfer, K., Cochran, H., Bothfeld, W., & Hardin, J. (2016). CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis. PLOS GENETICS. 12(11), e1006415-e1006415.
- Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., ... Bae, J. S. (2016). Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356. AUTOPHAGY. 12(2), 443-443.
- Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Arozena, A. A., ... Bae, J. S. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). AUTOPHAGY. 12(1), 1-222.
- Walck-Shannon, E., Reiner, D., & Hardin, J. (2015). Polarized rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis of c. Elegans. DEVELOPMENT. 142(20), 3549-3560.
- Kidd, A. R., MuÃ±iz-Medina, V., Der, C. J., Cox, A. D., & Reiner, D. J. (2015). The C. Elegans Chp/Wrch ortholog CHW-1 contributes to LIN-18/Ryk and LIN-17/ frizzled signaling in cell polarity. PLOS ONE. 10(7), e0133226-e0133226.
- Martin, T. D., Chen, X. W., Kaplan, R., Saltiel, A. R., Walker, C. L., Reiner, D. J., & Der, C. J. (2014). Ral and Rheb GTPase Activating Proteins Integrate mTOR and GTPase Signaling in Aging, Autophagy, and Tumor Cell Invasion. MOLECULAR CELL. 53(2), 209-220.
- Gentry, L. R., Martin, T. D., Reiner, D. J., & Der, C. J. (2014). Ral small GTPase signaling and oncogenesis: More than just 15 minutes of fame. BBA - Molecular Cell Research. 1843(12), 2976-2988.
- Dickinson, D. J., Ward, J. D., Reiner, D. J., & Goldstein, B. (2013). Engineering the Caenorhabditis elegans genome using Cas9-triggered homologous recombination. NATURE METHODS. 10(10), 1028-1034.
- Peters, E. C., Gossett, A. J., Goldstein, B., Der, C. J., & Reiner, D. J. (2013). Redundant canonical and noncanonical Caenorhabditis elegans p21-activated kinase signaling governs distal tip cell migrations. G3 (Bethesda). 3(2), 181-195.
- Zand, T. P., Reiner, D. J., & Der, C. J. (2011). Ras Effector Switching Promotes Divergent Cell Fates in C. elegans Vulval Patterning. DEVELOPMENTAL CELL. 20(1), 84-96.
- Reiner, D. J. (2011). Ras effector switching as a developmental strategy. Small GTPases. 2(2), 109-112.
- Neel, N. F., Martin, T. D., Stratford, J. K., Zand, T. P., Reiner, D. J., & Der, C. J. (2011). The RalGEF-ral effector signaling network: The road less traveled for anti-ras drug discovery. Genes Cancer. 2(3), 275-287.
- GonzÃ¡lez-PÃ©rez, V., Reiner, D. J., Alan, J. K., Mitchell, C., Edwards, L. J., Khazak, V., Der, C. J., & Cox, A. D. (2010). Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells. Journal of Molecular Signaling. 5, 2-2.
- Reiner, D. J., Ailion, M., Thomas, J. H., & Meyer, B. J. (2008). C. elegans Anaplastic Lymphoma Kinase Ortholog SCD-2 Controls Dauer Formation by Modulating TGF-Î² Signaling. CURRENT BIOLOGY. 18(15), 1101-1109.
- Reiner, D. J., GonzÃ¡lez-PÃ©rez, V., Der, C. J., & Cox, A. D. (2008). Use of Caenorhabditis elegans to Evaluate Inhibitors of Ras Function In Vivo. APPLICATIONS OF CHIMERIC GENES AND HYBRID PROTEINS, PT C. 439, 425-449.
- Reiner, D., Weinshenker, D., Tian, H., Thomas, J., Nishiwaki, K., Miwa, J., ... Garcia, L. (2006). Behavioral genetics of Caenorhabditis elegans unc-103-encoded erg-like K⁺channel. JOURNAL OF NEUROGENETICS. 20(1-2), 41-66.
- Petersen, C. I., McFarland, T. R., Stepanovic, S. Z., Yang, P., Reiner, D. J., Hayashi, K., ... Balser, J. R. (2004). In vivo identification of genes that modify either-a-go-go-related gene activity in Caenorhabditis elegans may also affect human cardiac arrhythmia. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 101(32), 11773-11778.
- Reiner, D. J., Newton, E. M., Tian, H., & Thomas, J. H. (1999). Diverse behavioural defects caused by mutations in Caenorhabditis elegans unc-43 CaM kinase II. NATURE. 402(6758), 199-202.
- Fuchs, A. F., Reiner, D., & Pong, M. (1996). Transfer of gain changes from targeting to other types of saccade in the monkey: Constraints on possible sites of saccadic gain adaptation. J Neurophysiol. 76(4), 2522-2535.
- Reiner, D. J., Weinshenker, D., & Thomas, J. H. (1995). Analysis of dominant mutations affecting muscle excitation in Caenorhabditis elegans. GENETICS. 141(3), 961-976.
- Reiner, D. J., & Thomas, J. H. (1995). Reversal of a muscle response to GABA during C. elegans male development. J Neurosci. 15(9), 6094-6102.
conference paper
- Gentry, L. R., Martin, T. D., Reiner, D. J., & Der, C. J. (2014). Mechanistic dissection of Ral GTPase signaling in driving KRAS-dependent pancreatic cancer growth. MOLECULAR CANCER RESEARCH. A08-A08.

principal investigator on

Novel Signals Regulate Cell Fate Patterning awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2017 - 2021
Global Changes In the 3'UTRome Toggle Responsiveness To Growth Factors awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2017 - 2020
Global Changes In the 3'UTRome Toggle Responsiveness To Growth Factors awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2017 - 2020
Global Changes In the 3'UTRome Toggle Responsiveness To Growth Factors awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2017 - 2020
The Ral Small GTPase In C. elegans development awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2013 - 2016

teaching activities

BIOC523 Extracellular Matrix Instructor
BIOC545 Adv Molecular Biol & Genetics Instructor
GENE491 Hnr-research Instructor
IBST691 Research Credit: Medical Sci Instructor
IBST691 Research Credit: Medical Sci Instructor
IBST691 Research Credit: Medical Sci Instructor
MSCI601 Contem Top In Adv Cell Bio I Instructor
MSCI601 Contem Top In Adv Cell Bio I Instructor
MSCI685 Directed Studies Instructor
NSCI511 Sci Policy & Ethics-rice/ibt Instructor

Email

dreiner@tamu.edu

First Name

David

Last Name

Reiner

mailing address

Texas A&M Health Science Center

Ibt Center For Translational Cancer Research

1201 TAMUS

Houston, TX 77030-3303

USA

Reiner, David Associate Professor

Positions

Academic Background

education and training

Publications

selected publications

academic article

conference paper

Grants/awards

principal investigator on

Recent Courses

teaching activities

Contact

Email

First Name

Last Name

mailing address