HR job title
- Associate Professor
- Contact Info
- 1 979 436 0763
Bayless, Kayla Associate Professor
Positions
- Associate Professor, Cell Biology and Genetics, Texas A&M University Naresh K. Vashisht College of Medicine
My laboratory conducts research in two areas of molecular and cellular medicine: the mechanism through which primary human endothelial cells invade into 3D matrices, and communication between invading endothelial cells and their surrounding 3D collagen matrix.
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Overview
Publications
selected publications
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academic article
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Bayless, K. J.
(2023).
Direct Involvement of CD8+ T Cells in Retinal Angiogenesis. Arteriosclerosis, Thrombosis and Vascular Biology.
43(4), 537-539.
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Banerjee, P., Kumaravel, S., Roy, S., Gaddam, N., Odeh, J., Bayless, K. J., Glaser, S., & Chakraborty, S.
(2023).
Conjugated Bile Acids Promote Lymphangiogenesis by Modulation of the Reactive Oxygen Species-p90RSK-Vascular Endothelial Growth Factor Receptor 3 Pathway. Cells.
12(4), 526-526.
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Sveeggen, T. M., Abbey, C. A., Smith, R. L., Salinas, M. L., Chapkin, R. S., & Bayless, K. J.
(2023).
Annexin A2 modulates phospholipid membrane composition upstream of Arp2 to control angiogenic sprout initiation. The FASEB Journal.
37(1), e22715.
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Ko, G., Yu, F., Bayless, K. J., & Ko, M. L.
(2022).
MicroRNA-150 (miR-150) and Diabetic Retinopathy: Is miR-150 Only a Biomarker or Does It Contribute to Disease Progression?. 23(20), 12099-12099.
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Wilcox, B. K., Henley, M. R., Navaneethabalakrishnan, S., Martinez, K. A., Pournouri, A., Goodlett, B. L., ... Mitchell, B. M.
(2022).
Hypertensive Stimuli Indirectly Stimulate Lymphangiogenesis through Immune Cell Secreted Factors. 11(14), 2139-2139.
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Banerjee, P., Roy, S., Kumaravel, S., Gaddam, N., Odeh, J., White, T., ... Chakraborty, S.
(2022).
Conjugated Bile Acids activate Reactive Oxygen Speciesp90RSKVascular Endothelial Growth Factor Receptor 3 signaling axis to promote lymphangiogenesis. 36(S1),
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Fang, X., Ni, N., Wang, X., Tian, Y., Ivanov, I., Rijnkels, M., ... Li, Q.
(2022).
EZH2 and Endometrial Cancer Development: Insights from a Mouse Model. 11(5), 909-909.
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Roy, S., Kumaravel, S., Banerjee, P., White, T. K., O'Brien, A., Seelig, C., ... Chakraborty, S.
(2021).
Tumor Lymphatic Interactions Induce CXCR2-CXCL5 Axis and Alter Cellular Metabolism and Lymphangiogenic Pathways to Promote Cholangiocarcinoma. 10(11), 3093-3093.
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Mao, D. Y., Kleinjan, M. L., Jilishitz, I., Swaminathan, B., Obinata, H., Komarova, Y. A., ... Kitajewski, J. K.
(2021).
CLIC1 and CLIC4 mediate endothelial S1P receptor signaling to facilitate Rac1 and RhoA activity and function. 14(679), eabc0425.
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Roy, S., Banerjee, P., Ekser, B., Bayless, K., Zawieja, D., Alpini, G., Glaser, S. S., & Chakraborty, S.
(2021).
Targeting Lymphangiogenesis and Lymph Node Metastasis in Liver Cancer. American Journal of Pathology.
191(12), 2052-2063.
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Dunlap, K. A., White, B. G., Erikson, D. W., Satterfield, M. C., Pfarrer, C., Wu, G., ... Johnson, G. A.
(2020).
FTY720, a sphingosine analog, altered placentome histoarchitecture in ewes. Journal of Animal Science and Biotechnology.
11(1), 2.
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Kumaravel, S., Abbey, C. A., Bayless, K. J., & Chakraborty, S.
(2020).
The 1-integrin plays a key role in LEC invasion in an optimized 3-D collagen matrix model. American Journal of Physiology: Cell Physiology.
319(6), C1045-C1058.
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Johnson, G. A., Bazer, F. W., Burghardt, R. C., Spencer, T. E., Wu, G., & Bayless, K. J.
(2020).
Conceptus-uterus interactions in pigs: endometrial gene expression in response to estrogens and interferons from conceptuses. Bioscientifica Proceedings.
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Roy, S., Kumaravel, S., Sharma, A., Duran, C. L., Bayless, K. J., & Chakraborty, S.
(2020).
Hypoxic tumor microenvironment: Implications for cancer therapy. Experimental Biology and Medicine.
245(13), 1073-1086.
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Wing, T. T., Erikson, D. W., Burghardt, R. C., Bazer, F. W., Bayless, K. J., & Johnson, G. A.
(2020).
OPN binds alpha V integrin to promote endothelial progenitor cell incorporation into vasculature. REPRODUCTION.
159(4), 465-478.
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Seo, H., Li, X., Wu, G., Bazer, F. W., Burghardt, R. C., Bayless, K. J., & Johnson, G. A.
(2020).
Mechanotransduction drives morphogenesis to develop folding during placental development in pigs. Placenta.
90, 62-70.
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Fang, X., Ni, N., Gao, Y., Lydon, J. P., Ivanov, I., Rijnkels, M., Bayless, K. J., & Li, Q.
(2020).
Transforming growth factor beta signaling and decidual integrity in mice. Biology of Reproduction.
103(6), 1186-1198.
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Fu, H., Sun, Y. u., Shao, Y., Saredy, J., Cueto, R., Liu, L. u., ... Yang, X.
(2020).
Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis. 11, 595813.
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Shi, L., Zhao, M., Abbey, C. A., Tsai, S., Xie, W., Pham, D., ... Ko, G.
(2019).
Newly Identified Peptide, Peptide Lv, Promotes Pathological Angiogenesis. Journal of the American Heart Association.
8(22), e013673.
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Bayless, K., Duran, C. L., Abbey, C. A., & Kang, H. A.
(2019).
Assembly of a mechanosensitive complex is required to initiate sprouting angiogenesis. The FASEB Journal.
33(S1), 83.2-83.2.
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Frank, J. W., Bazer, F. W., Burghardt, R. C., Bayless, K. J., & Johnson, G. A.
(2019).
Integrin is necessary for the attachment of trophectoderm cells to osteopontin to mediate adhesion of the conceptus to the uterus during implantation in pigs. Bioscientifica Proceedings.
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Fang, X., Ni, N., Lydon, J. P., Ivanov, I., Bayless, K. J., Rijnkels, M., & Li, Q.
(2019).
Enhancer of Zeste 2 Polycomb Repressive Complex 2 Subunit Is Required for Uterine Epithelial Integrity. American Journal of Pathology.
189(6), 1212-1225.
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van Engeland, N., Suarez Rodriguez, F., Rivero-Mller, A., Ristori, T., Duran, C. L., Stassen, O., ... Sahlgren, C. M.
(2019).
Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress. Scientific Reports.
9(1), 12415.
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Kang, H., Hong, Z., Zhong, M., Klomp, J., Bayless, K. J., Mehta, D., ... Malik, A. B.
(2019).
Piezo1 mediates angiogenesis through activation of MT1-MMP signaling. American Journal of Physiology: Cell Physiology.
316(1), C92-C103.
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Howell, D. W., Peak, C. W., Bayless, K. J., & Gaharwar, A. K.
(2018).
Angiogenesis: 2D Nanosilicates Loaded with Proangiogenic Factors Stimulate Endothelial Sprouting (Adv. Biosys. 7/2018). Advanced Biology.
2(7), 1870061-1870061.
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Howell, D. W., Peak, C. W., Bayless, K. J., & Gaharwar, A. K.
(2018).
2D Nanosilicates Loaded with Proangiogenic Factors Stimulate Endothelial Sprouting. Advanced Biology.
2(7), 1800092-1800092.
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Bondos, S., Howell, D., Tsai, S., & Bayless, K.
(2018).
Functionalizing Proteinbased Materials with Biomolecules. The FASEB Journal.
32(S1), 230.1-230.1.
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Duran, C. L., Abbey, C. A., & Bayless, K. J.
(2018).
Establishment of a three-dimensional model to study human uterine angiogenesis. Molecular Human Reproduction.
24(2), 74-93.
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Lokhande, G., Carrow, J. K., Thakur, T., Xavier, J. R., Parani, M., Bayless, K. J., & Gaharwar, A. K.
(2018).
Nanoengineered injectable hydrogels for wound healing application. Acta Biomaterialia.
70, 35-47.
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Duran, C. L., Kaunas, R., & Bayless, K. J.
(2018).
S1P Synergizes with Wall Shear Stress and Other Angiogenic Factors to Induce Endothelial Cell Sprouting Responses. Methods in molecular biology (Clifton, N.J.).
1697, 99-115.
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Antfolk, D., Sjqvist, M., Cheng, F., Isoniemi, K., Duran, C. L., Rivero-Muller, A., ... Sahlgren, C. M.
(2017).
Selective regulation of Notch ligands during angiogenesis is mediated by vimentin. Proceedings of the National Academy of Sciences of the United States of America.
114(23), E4574-E4581.
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Frank, J. W., Seo, H., Burghardt, R. C., Bayless, K. J., & Johnson, G. A.
(2017).
ITGAV (alpha v integrins) bind SPP1 (osteopontin) to support trophoblast cell adhesion. REPRODUCTION.
153(5), 695-706.
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Duran, C. L., Howell, D. W., Dave, J. M., Smith, R. L., Torrie, M. E., Essner, J. J., & Bayless, K. J.
(2017).
Molecular Regulation of Sprouting Angiogenesis. Comprehensive Physiology.
8(1), 153-235.
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Howell, D. W., Duran, C. L., Tsai, S., Bondos, S. E., & Bayless, K. J.
(2016).
Functionalization of Ultrabithorax Materials with Vascular Endothelial Growth Factor Enhances Angiogenic Activity. Biomacromolecules.
17(11), 3558-3569.
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Dave, J. M., Abbey, C. A., Duran, C. L., Seo, H., Johnson, G. A., & Bayless, K. J.
(2016).
Hic-5 mediates the initiation of endothelial sprouting by regulating a key surface metalloproteinase. Journal of Cell Science.
129(4), 743-756.
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Duran, C. L., Lee, D. W., Jung, J., Ravi, S., Pogue, C. B., Toussaint, L. G., Bayless, K. J., & Sitcheran, R.
(2016).
NIK regulates MT1-MMP activity and promotes glioma cell invasion independently of the canonical NF-B pathway. Oncogenesis.
5(6), e231-e231.
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Churion, K. A., Rogers, R. E., Bayless, K. J., & Bondos, S. E.
(2016).
Separating full-length protein from aggregating proteolytic products using filter flow-through purification. Analytical Biochemistry.
514, 8-11.
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Howell, D. W., Tsai, S., Churion, K., Patterson, J., Abbey, C., Atkinson, J. T., ... Bondos, S. E.
(2015).
Identification of multiple dityrosine bonds in materials composed of the Drosophila protein Ultrabithorax. Advanced Functional Materials.
25(37), 5988-5998.
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Bake, S., Dave, J., Bayless, K., & Sohrabji, F.
(2015).
Abstract W MP51: Insulin-like Growth Factor (igf-1) Enhances The Angiogenic Response Of Aging Endothelial Cells. Stroke.
46(suppl_1),
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Gao, Y., Duran, S., Lydon, J. P., DeMayo, F. J., Burghardt, R. C., Bayless, K. J., Bartholin, L., & Li, Q.
(2015).
Constitutive activation of transforming growth factor Beta receptor 1 in the mouse uterus impairs uterine morphology and function. Biology of Reproduction.
92(2), 34-13.
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Kang, H., Duran, C. L., Abbey, C. A., Kaunas, R. R., & Bayless, K. J.
(2015).
Fluid shear stress promotes proprotein convertase-dependent activation of MT1-MMP. Biochemical and Biophysical Research Communications.
460(3), 596-602.
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Dave, J. M., & Bayless, K. J.
(2014).
Vimentin as an integral regulator of cell adhesion and endothelial sprouting. Microcirculation.
21(4), 333-344.
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Bai, Y., Lee, P., Gibbs, H. C., Bayless, K. J., & Yeh, A. T.
(2014).
Dynamic multicomponent engineered tissue reorganization and matrix deposition measured with an integrated nonlinear optical microscopy-optical coherence microscopy system. Journal of Biomedical Optics.
19(3), 36014-036014.
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Gao, Y., Bayless, K. J., & Li, Q.
(2014).
TGFBR1 is required for mouse myometrial development. Molecular Endocrinology.
28(3), 380-394.
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Abbey, C. A., & Bayless, K. J.
(2014).
Matrix density alters zyxin phosphorylation, which limits peripheral process formation and extension in endothelial cells invading 3D collagen matrices. Matrix Biology.
38, 36-47.
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Patterson, J. L., Abbey, C. A., Bayless, K. J., & Bondos, S. E.
(2014).
Materials composed of the Drosophila melanogaster protein ultrabithorax are cytocompatible. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A.
102(1), 97-104.
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Dave, J. M., Kang, H., Abbey, C. A., Maxwell, S. A., & Bayless, K. J.
(2013).
Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK). Journal of Biological Chemistry.
288(42), 30720-30733.
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Lee, D. W., Ramakrishnan, D., Valenta, J., Parney, I. F., Bayless, K. J., & Sitcheran, R.
(2013).
The NF-B RelB protein is an oncogenic driver of mesenchymal glioma. PLoS ONE.
8(2), e57489-e57489.
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Lee, P., Bai, Y., Smith, R. L., Bayless, K. J., & Yeh, A. T.
(2013).
Angiogenic responses are enhanced in mechanically and microscopically characterized, microbial transglutaminase crosslinked collagen matrices with increased stiffness. Acta Biomaterialia.
9(7), 7178-7190.
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White, B. G., Frank, J. W., Burghardt, R. C., Satterfield, M. C., Bazer, F. W., Johnson, G. A., & Bayless, K. J.
(2012).
Antagonism of the S1P Signaling Pathway Affects Placental and Fetal Development. Biology of Reproduction.
87(Suppl_1), 71-71.
-
Su, S., & Bayless, K. J.
(2012).
Utilizing sphingosine-1-phosphate to stimulate sprouting angiogenesis. Methods in molecular biology (Clifton, N.J.).
874, 201-213.
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Kwak, H., Kang, H., Dave, J. M., Mendoza, E. A., Su, S., Maxwell, S. A., & Bayless, K. J.
(2012).
Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation. ANGIOGENESIS.
15(2), 287-303.
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Ang, H., Kaunas, R. R., & Bayless, K. J.
(2012).
Fluid shear stress and sphingosine 1-phosphate promote Filamin A membrane translocation and complex formation with VE-cadherin during endothelial cell invasion. Molecular Biology of the Cell.
23.
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Kang, H., Kwak, H., Kaunas, R., & Bayless, K. J.
(2011).
Fluid shear stress and sphingosine 1-phosphate activate calpain to promote membrane type 1 matrix metalloproteinase (MT1-MMP) membrane translocation and endothelial invasion into three-dimensional collagen matrices. Journal of Biological Chemistry.
286(49), 42017-42026.
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Bayless, K. J., & Johnson, G. A.
(2011).
Role of the cytoskeleton in formation and maintenance of angiogenic sprouts. 48(5), 369-385.
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Maxwell, S. A., Cherry, E. M., & Bayless, K. J.
(2011).
Akt, 14-3-3, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma. 52(5), 849-864.
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Kaunas, R., Kang, H., & Bayless, K. J.
(2011).
Synergistic Regulation of Angiogenic Sprouting by Biochemical Factors and Wall Shear Stress. Cellular and Molecular Bioengineering.
4(4), 547-559.
-
Su, S., Maxwell, S. A., & Bayless, K. J.
(2010).
Annexin 2 regulates endothelial morphogenesis by controlling AKT activation and junctional integrity. Journal of Biological Chemistry.
285(52), 40624-40634.
-
Frank, J. W., Li, X., Erikson, D. W., Wu, G., Bazer, F. W., Bayless, K. J., Burghardt, R. C., & Johnson, G. A.
(2010).
Expression of SPP1 (Osteopontin) and the Aggregation of Integrins into Focal Adhesions Is an Adaptation to Mechanical Forces at the Uterine-Placental Interface in Pigs. Biology of Reproduction.
83(Suppl_1), 445-445.
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Bayless, K. J., Erikson, D. W., Frank, J. W., Joyce, M. M., Burghardt, R. C., Bazer, F. W., & Johnson, G. A.
(2010).
Recruitment and Modulation of Porcine Endothelial Progenitor Cells by Secreted Phosphoprotein 1 (SPP1, Osteopontin). Biology of Reproduction.
83(Suppl_1), 94-94.
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Erikson, D. W., Hsieh, Y., Hayashi, K., Burghardt, R. C., Bayless, K. J., Chang, P., & Johnson, G. A.
(2010).
SPP1 (Osteopontin) and SPARC (Osteonectin) May Interact Developmentally During Mouse Pregnancy. Biology of Reproduction.
83(Suppl_1), 80-80.
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Kim, J., Erikson, D. W., Burghardt, R. C., Spencer, T. E., Wu, G., Bayless, K. J., Johnson, G. A., & Bazer, F. W.
(2010).
Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1/mTOR, to support attachment and force-generated migration of trophectoderm cells. Matrix Biology.
29(5), 369-382.
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Dunlap, K. A., Kwak, H., Burghardt, R. C., Bazer, F. W., Magness, R. R., Johnson, G. A., & Bayless, K. J.
(2010).
The sphingosine 1-phosphate (S1P) signaling pathway is regulated during pregnancy in sheep. Biology of Reproduction.
82(5), 876-887.
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Bazer, F. W., Wu, G., Spencer, T. E., Johnson, G. A., Burghardt, R. C., & Bayless, K.
(2010).
Novel pathways for implantation and establishment and maintenance of pregnancy in mammals. Molecular Human Reproduction.
16(3), 135-152.
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Erikson, D. W., Burghardt, R. C., Bayless, K. J., & Johnson, G. A.
(2009).
Secreted phosphoprotein 1 (SPP1, osteopontin) binds to integrin alpha v beta 6 on porcine trophectoderm cells and integrin alpha v beta 3 on uterine luminal epithelial cells, and promotes trophectoderm cell adhesion and migration. Biology of Reproduction.
81(5), 814-825.
-
Dunlap, K. A., Li, X., Satterfield, M. C., Burghardt, R. C., Erikson, D. W., Halvorsen, M. L., ... Johnson, G. A.
(2009).
Antagonism of the Sphingosine 1-Phosphate (S1P) Signaling Pathway in Pregnant Ewes Alters Placentome Architecture, Amino Acid Transport, and Fetal Growth. Biology of Reproduction.
81(Suppl_1), 427-427.
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Burghardt, R. C., Burghardt, J. R., Taylor, J. D., Reeder, A. T., Nguen, B. T., Spencer, T. E., Bayless, K. J., & Johnson, G. A.
(2009).
Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at maternal-conceptus interface and uterine wall during ovine pregnancy. 137(3), 567-582.
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Kwak, H., Mendoza, E. A., & Bayless, K. J.
(2009).
ADAM17 co-purifies with TIMP-3 and modulates endothelial invasion responses in three-dimensional collagen matrices. Matrix Biology.
28(8), 470-479.
-
Bayless, K. J., Kwak, H., & Su, S.
(2009).
Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices. Nature Protocols.
4(12), 1888-1898.
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Lee, P., Yeh, A. T., & Bayless, K. J.
(2009).
Nonlinear optical microscopy reveals invading endothelial cells anisotropically alter three-dimensional collagen matrices. Experimental Cell Research.
315(3), 396-410.
-
Johnson, G. A., Bazer, F. W., Burghardt, R. C., Spencer, T. E., Wu, G., & Bayless, K. J.
(2009).
Conceptus-uterus interactions in pigs: endometrial gene expression in response to estrogens and interferons from conceptuses. Society of Reproduction and Fertility supplement.
66, 321-332.
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Larson, A. M., Lee, A., Lee, P., Bayless, K. J., & Yeh, A. T.
(2009).
ULTRASHORT PULSE MULTISPECTRAL NONLINEAR OPTICAL MICROSCOPY. Journal of Innovative Optical Health Sciences.
2(1), 27-35.
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Kang, H., Bayless, K. J., & Kaunas, R.
(2008).
Fluid shear stress modulates endothelial cell invasion into three-dimensional collagen matrices. American Journal of Physiology. Heart and Circulatory Physiology.
295(5), H2087-H2097.
-
Su, S., Mendoza, E. A., Kwak, H., & Bayless, K. J.
(2008).
Molecular profile of endothelial invasion of three-dimensional collagen matrices: insights into angiogenic sprout induction in wound healing. American Journal of Physiology: Cell Physiology.
295(5), C1215-C1229.
-
Dunlap, K. A., Erikson, D. W., Burghardt, R. C., White, F. J., Reed, K. M., Farmer, J. L., ... Johnson, G. A.
(2008).
Progesterone and placentation increase secreted phosphoprotein one (SPP1 or osteopontin) in uterine glands and stroma for histotrophic and hematotrophic support of ovine pregnancy. Biology of Reproduction.
79(5), 983-990.
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Lakshman, N., Kim, A., Bayless, K. J., Davis, G. E., & Petroll, W. M.
(2007).
Rho plays a central role in regulating local cell-matrix mechanical interactions in 3D culture. Cytoskeleton.
64(6), 434-445.
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Saunders, W. B., Bohnsack, B. L., Faske, J. B., Anthis, N. J., Bayless, K. J., Hirschi, K. K., & Davis, G. E.
(2006).
Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. Journal of Cell Biology.
175(1), 179-191.
-
Rivera, A., Mavila, A., Bayless, K. J., Davis, G. E., & Maxwell, S. A.
(2006).
Cyclin A1 is a p53-induced gene that mediates apoptosis, G2/M arrest, and mitotic catastrophe in renal, ovarian, and lung carcinoma cells. Cellular and Molecular Life Sciences.
63(12), 1425-1439.
-
Kamei, M., Saunders, W. B., Bayless, K. J., Dye, L., Davis, G. E., & Weinstein, B. M.
(2006).
Endothelial tubes assemble from intracellular vacuoles in vivo. Nature.
442(7101), 453-456.
-
Joshi, S., Guleria, R. S., Pan, J., Bayless, K. J., Davis, G. E., Dipette, D., & Singh, U. S.
(2006).
Ethanol impairs Rho GTPase signaling and differentiation of cerebellar granule neurons in a rodent model of fetal alcohol syndrome. Cellular and Molecular Life Sciences.
63(23), 2859-2870.
-
Covington, M. D., Bayless, K. J., Burghardt, R. C., Davis, G. E., & Parrish, A. R.
(2005).
Ischemia-induced cleavage of cadherins in NRK cells: evidence for a role of metalloproteinases. American Journal of Physiology: Renal Physiology.
289(2), F280-F288.
-
Saunders, W. B., Bayless, K. J., & Davis, G. E.
(2005).
MMP-1 activation by serine proteases and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. Journal of Cell Science.
118(Pt 10), 2325-2340.
-
Richardson, K. E., Tannous, P., Berenji, K., Nolan, B., Bayless, K. J., Davis, G. E., Rothermel, B. A., & Hill, J. A.
(2005).
Guanosine triphosphatase activation occurs downstream of calcineurin in cardiac hypertrophy*. Journal of Investigative Medicine.
53(8), 414-424.
-
Bayless, K. J., & Davis, G. E.
(2004).
Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho. 279(12), 11686-11695.
-
Bayless, K. J., & Davis, G. E.
(2003).
Sphingosine-1-phosphate markedly induces matrix metalloproteinase and integrin-dependent human endothelial cell invasion and lumen formation in three-dimensional collagen and fibrin matrices. Biochemical and Biophysical Research Communications.
312(4), 903-913.
-
Davis, G. E., & Bayless, K. J.
(2003).
An integrin and Rho GTPase-dependent pinocytic vacuole mechanism controls capillary lumen formation in collagen and fibrin matrices. 10(1), 27-44.
-
Davis, G. E., Bayless, K. J., & Mavila, A.
(2002).
Molecular basis of endothelial cell morphogenesis in three-dimensional extracellular matrices. Anatomical Record.
268(3), 252-275.
-
Bayless, K. J., & Davis, G. E.
(2002).
The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices. Journal of Cell Science.
115(6), 1123-1136.
-
Bayless, K. J., & Davis, G. E.
(2002).
The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices. Journal of Cell Science.
115(Pt 6), 1123-1136.
-
Bell, S. E., Mavila, A., Salazar, R., Bayless, K. J., Kanagala, S., Maxwell, S. A., & Davis, G. E.
(2001).
Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. Journal of Cell Science.
114(Pt 15), 2755-2773.
-
Bayless, K. J., & Davis, G. E.
(2001).
Identification of dual alpha 4beta1 integrin binding sites within a 38 amino acid domain in the N-terminal thrombin fragment of human osteopontin. Journal of Biological Chemistry.
276(16), 13483-13489.
-
Davis, G. E., Black, S. M., & Bayless, K. J.
(2000).
Capillary morphogenesis during human endothelial cell invasion of three-dimensional collagen matrices. In Vitro Cellular and Developmental Biology - Animal.
36(8), 513-519.
-
Davis, G. E., Black, S. M., & Bayless, K. J.
(2000).
Capillary morphogenesis during human endothelial cell invasion of three-dimensional collagen matrices. 36(8), 513-519.
-
Davis, G. E., Bayless, K. J., Davis, M. J., & Meininger, G. A.
(2000).
Regulation of tissue injury responses by the exposure of matricryptic sites within extracellular matrix molecules. American Journal of Pathology.
156(5), 1489-1498.
-
Bayless, K. J., Salazar, R., & Davis, G. E.
(2000).
RGD-dependent vacuolation and lumen formation observed during endothelial cell morphogenesis in three-dimensional fibrin matrices involves the alpha(v)beta(3) and alpha(5)beta(1) integrins. American Journal of Pathology.
156(5), 1673-1683.
-
Bayless, K. J., Meininger, G. A., Scholtz, J. M., & Davis, G. E.
(1998).
Osteopontin is a ligand for the alpha4beta1 integrin. Journal of Cell Science.
111 ( Pt 9)(9), 1165-1174.
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Bayless, K. J., Meininger, G. A., Scholtz, M. J., & Davis, G. E.
(1998).
The 41 integrin binds osteopontin. The FASEB Journal.
12(5),
-
Bayless, K. J., Meininger, G. A., Scholtz, J. M., & Davis, G. E.
(1998).
Osteopontin is a ligand for the alpha4beta1 integrin. 111, Pt-9/.
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Bayless, K. J., Davis, G. E., & Meininger, G. A.
(1997).
Isolation and biological properties of osteopontin from bovine milk. Protein Expression and Purification.
9(3), 309-314.
-
Kaunas, R., Bayless, K. J., & Kang, H.
Fluid shear stress enhances the effects of sphingosine-1-phosphate on endothelial cell invasion into collagen matrices. Biorheology: an international journal.
45(1-2), 125-125.
-
Bayless, K. J.
(2023).
Direct Involvement of CD8+ T Cells in Retinal Angiogenesis. Arteriosclerosis, Thrombosis and Vascular Biology.
43(4), 537-539.
-
conference paper
-
Mendes, G. G., Howell, D. W., Tsai, S. P., Bayless, K. J., & Bondos, S. E.
(2019).
Engineering ubx-based materials to promote and guide neovascularization. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium.
26.
-
Kang, H., Kwak, H., Kaunas, R., & Bayless, K. J.
(2010).
Effects of Fluid Shear Stress on Endothelial Cell Invasion Into Three-Dimensional Matrices. 427-428.
-
Kang, H., Bayless, K. J., & Kaunas, R.
(2009).
Fluid Shear Stress Modulates S1P-Induced Endothelial Cell Invasion Into Three-Dimensional Matrices. 943-944.
-
Clarke, D., Stack, J., Bayless, K., & Bix, G.
(2008).
Endorepellin and endostatin affect the neurovascular unit in vitro. Journal of Neurochemistry.
77-77.
-
Larson, A. M., Lee, P., Lee, A., Bayless, K. J., & Yeh, A. T.
(2008).
Fiber Optically Delivered Laser Pulses for Multispectral Nonlinear Optical Microscopy. Optics InfoBase Conference Papers.
ftux1.
-
Kang, H., Bayless, K. J., & Kaunas, R.
(2007).
Effects of fluid shear stress on endothelial cell invasion into three-dimensional matrices. 287-288.
-
Bayless, K. J., & Davis, G. E.
(2002).
AFFINITY OF OSTEOPONTIN FOR LEUKOCYTE INTEGRINS, EXTRACELLULAR MATRICES AND APOPTOTIC CELLS. 13-14.
-
Davis, G. E., & Bayless, K. J.
(2002).
MATRICRYPTIC INTEGRIN BINDING SITES IN OSTEOPONTIN REGULATE INFLAMMATION. 17-18.
-
Mendes, G. G., Howell, D. W., Tsai, S. P., Bayless, K. J., & Bondos, S. E.
(2019).
Engineering ubx-based materials to promote and guide neovascularization. Annual Meeting- Society for Biomaterials in Conjunction with the International Biomaterials Symposium.
26.
-
institutional repository document
-
Zhao, F., Sharma, D., Sharma, A., Hu, L., Chen, T., Voon, S., ... Walsh, A.
(2022).
Perfusability and immunogenicity of implantable pre-vascularized tissues recapitulating native capillary network
-
Sveeggen, T. M., Abbey, C. A., Smith, R. L., & Bayless, K. J.
(2022).
Annexin A2 modulates phospholipid membrane composition upstream of Arp2 to control angiogenic sprout initiation
-
Zhao, F., Sharma, D., Sharma, A., Hu, L., Chen, T., Voon, S., ... Walsh, A.
(2022).
Perfusability and immunogenicity of implantable pre-vascularized tissues recapitulating native capillary network
-
patent
-
Bondos, S., Bayless, K., Matthews, K., Patterson, J., Abbey, C., Howell, D., ... Northern, K.
(2021).
Functionalized protein-based materials and their uses
-
Bondos, S., Bayless, K., Matthews, K., Patterson, J., Abbey, C., Howell, D., ... Northern, K.
(2021).
Functionalized protein-based materials and their uses
Research
principal investigator on
- NIK Promotes a Leader Cell Phenotype in Glioma awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2017 - 2020
- Filamins stabilize a transmembrane complex to initiate angiogenesis awarded by American Heart Association - (New York, New York, United States) 2016 - 2017
- Mechanisms of Angiogenic Switch Activation During Wound Repair awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2012 - 2016
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- GENE691 Research Instructor
- MSCI630 Pathogenesis Of Human Disease Instructor
- MSCI691 Research Credit: Medical Sci Instructor
Works By Students
chaired theses and dissertations
-
Dave, Jui Mayank (2014-12). Identification of Scaffold Proteins RACK1 and Hic-5 as Regulators of Endothelial Sprouting Resoponses.
-
Duran, Camille L (2017-04). Noncanonical NF-KB Signaling Drives Glioma Invasion by Promoting MT1-MMP Activation, Pseudopodia Formation, and ITGA11 Expression.
-
Kang, Ho Jin (2012-07). The Synergic Effects of Flow and Sphingosine 1-Phosphate on Sprouting Angiogenesis Into Three-Dimensional Collagen Matrices.
-
Smith, Rebecca (2014-01). Annexin A2 is Required for Endothelial Cell Junctional Response to S1P.
-
Su, Shih-Chi (2011-08). Study of Endothelial Morphogenesis in Three-Dimensional Collagen Matrices.
-
Tsai, Shang-Pu (2016-05). Ubx as a Novel Protein-Based Material: Structural Insights, Functionalization via Gene Fusion and Biomedical Applications.
Background
education and training
- Ph.D. in Medical Physiology, Texas A&M Health Science Center - (College Station, Texas, United States) 1999
- B.S. in Molecular Biology, Texas Lutheran University - (Seguin, Texas, United States) 1994
- Texas A&M Health Science Center - (College Station, Texas, United States) , Postdoctoral Training 2004
awards and honors
Contact
first name
- Kayla
has last name
- Bayless
mailing address
-
Texas A&M Health Science Center
Molecular And Cellular Medicine
1114 TAMUS
College Station, TX 77843-1114
USA
Other
- kaylajb@tamu.edu