HR job title
- Research Professor
- Contact Info
- 1 979 845 2871
Bloomfield, Susan Professor
Positions
My research interests focus on the integrative physiology of bone, with specific reference to adaptations to disuse, microgravity, and caloric deficiency.
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Overview
Publications
selected publications
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academicarticle
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Wiggs, M. P., Lee, Y., Shimkus, K. L., O'Reilly, C. I., Lima, F., Macias, B. R., ... Fluckey, J. D.
(2023).
Combined effects of heavy ion exposure and simulated Lunar gravity on skeletal muscle. Life Sciences in Space Research.
37, 39-49.
-
Bloomfield, S. A., Dunbar, B. J., Schmit, C. D., Sawyer, A. J., & Charles, J. B.
(2022).
Developing an international database on long-term health effects of spaceflight. Acta Astronautica.
198, 347-353.
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Little-Letsinger, S. E., Turner, N. D., Ford, J. R., Suva, L. J., & Bloomfield, S. A.
(2021).
Omega-3 fatty acid modulation of serum and osteocyte tumor necrosis factor- in adult mice exposed to ionizing radiation. Journal of applied physiology.
130(3), 627-639.
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Mantri, A. V., Allaway, H., Brezicha, J. E., Hogan, H. A., & Bloomfield, S. A.
(2021).
Oral Estradiol Impact on Mitigating Unloading-Induced Bone Loss in Ovary-Intact Rats. Aerospace Medicine and Human Performance.
92(2), 65-74.
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Allaway, H., Pierson, R. A., Invik, J., & Bloomfield, S. A.
(2021).
A rodent model of human dose-equivalent progestin-only implantable contraception. Reproductive Biology and Endocrinology.
19(1), 47.
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Metzger, C. E., Anand Narayanan, S., Phan, P. H., & Bloomfield, S. A.
(2020).
Hindlimb unloading causes regional loading-dependent changes in osteocyte inflammatory cytokines that are modulated by exogenous irisin treatment. 6(1), 28.
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Bokhari, R. S., Metzger, C. E., Black, J. M., Franklin, K. A., Boudreaux, R. D., Allen, M. R., ... Bloomfield, S. A.
(2019).
Positive impact of low-dose, high-energy radiation on bone in partial- and/or full-weightbearing mice. 5(1), 13.
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Metzger, C. E., Narayanan, S. A., Elizondo, J. P., Carter, A. M., Zawieja, D. C., Hogan, H. A., & Bloomfield, S. A.
(2019).
DSS-induced colitis produces inflammation-induced bone loss while irisin treatment mitigates the inflammatory state in both gut and bone. Scientific Reports.
9(1), 15144.
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Metzger, C. E., Narayanan, S. A., Zawieja, D. C., & Bloomfield, S. A.
(2019).
A moderately elevated soy protein diet mitigates inflammatory changes in gut and in bone turnover during chronic TNBS-induced inflammatory bowel disease. 44(6), 595-605.
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Metzger, C. E., Gong, S., Aceves, M., Bloomfield, S. A., & Hook, M. A.
(2019).
Osteocytes reflect a pro-inflammatory state following spinal cord injury in a rodent model. BONE.
120, 465-475.
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Narayanan, S. A., Metzger, C. E., Bloomfield, S. A., & Zawieja, D. C.
(2018).
Inflammation-induced lymphatic architecture and bone turnover changes are ameliorated by irisin treatment in chronic inflammatory bowel disease. The FASEB Journal.
32(9), 4848-4861.
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Metzger, C. E., Swift, S. N., Baek, K., De Souza, M. J., & Bloomfield, S. A.
(2018).
Fat and Lean Mass Predict Bone Mass During Energy Restriction in Sedentary and Exercising Rodents. Frontiers in Physiology.
9(SEP), 1346.
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Metzger, C. E., Brezicha, J. E., Elizondo, J. P., Narayanan, S. A., Hogan, H. A., & Bloomfield, S. A.
(2017).
Differential responses of mechanosensitive osteocyte proteins in fore- and hindlimbs of hindlimb-unloaded rats. 105, 26-34.
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Lang, T., Van Loon, J., Bloomfield, S., Vico, L., Chopard, A., Rittweger, J., ... Cavanagh, P. R.
(2017).
Towards human exploration of space: the THESEUS review series on muscle and bone research priorities. 3(1), 8.
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Lima, F., Swift, J. M., Greene, E. S., Allen, M. R., Cunningham, D. A., Braby, L. A., & Bloomfield, S. A.
(2017).
Exposure to Low-Dose X-Ray Radiation Alters Bone Progenitor Cells and Bone Microarchitecture. RADIATION RESEARCH.
188(4), 433-442.
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Metzger, C. E., Narayanan, A., Zawieja, D. C., & Bloomfield, S. A.
(2017).
Inflammatory Bowel Disease in a Rodent Model Alters Osteocyte Protein Levels Controlling Bone Turnover. Journal of Bone and Mineral Research.
32(4), 802-813.
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Macias, B. R., Lima, F., Swift, J. M., Shirazi-Fard, Y., Greene, E. S., Allen, M. R., ... Bloomfield, S. A.
(2016).
Simulating the Lunar Environment: Partial Weightbearing and High-LET Radiation-Induce Bone Loss and Increase Sclerostin-Positive Osteocytes. RADIATION RESEARCH.
186(3), 254-263.
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Metzger, C. E., Baek, K., Swift, S. N., De Souza, M. J., & Bloomfield, S. A.
(2016).
Exercise during energy restriction mitigates bone loss but not alterations in estrogen status or metabolic hormones. 27(9), 2755-2764.
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Bloomfield, S. A., Martinez, D. A., Boudreaux, R. D., & Mantri, A. V.
(2016).
Microgravity Stress: Bone and Connective Tissue. Comprehensive Physiology.
6(2), 645-686.
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Ritchie, L. E., Taddeo, S. S., Weeks, B. R., Lima, F., Bloomfield, S. A., Azcarate-Peril, M. A., ... Turner, N. D.
(2015).
Space Environmental Factor Impacts upon Murine Colon Microbiota and Mucosal Homeostasis. PLoS ONE.
10(6), e0125792-e0125792.
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Avin, K. G., Bloomfield, S. A., Gross, T. S., & Warden, S. J.
(2015).
Biomechanical aspects of the muscle-bone interaction. 13(1), 1-8.
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Shirazi-Fard, Y., Metzger, C. E., Kwaczala, A. T., Judex, S., Bloomfield, S. A., & Hogan, H. A.
(2015).
Moderate intensity resistive exercise improves metaphyseal cancellous bone recovery following an initial disuse period, but does not mitigate decrements during a subsequent disuse period in adult rats (vol 66, pg 296, 2014). 71, 265-265.
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Swift, S. N., Swift, J. M., & Bloomfield, S. A.
(2014).
Mechanical loading increases detection of estrogen receptor-alpha in osteocytes and osteoblasts despite chronic energy restriction. Journal of applied physiology.
117(11), 1349-1355.
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Swift, J. M., Swift, S. N., Allen, M. R., & Bloomfield, S. A.
(2014).
Beta-1 adrenergic agonist treatment mitigates negative changes in cancellous bone microarchitecture and inhibits osteocyte apoptosis during disuse. PLoS ONE.
9(9), e106904-e106904.
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Shirazi-Fard, Y., Metzger, C. E., Kwaczala, A. T., Judex, S., Bloomfield, S. A., & Hogan, H. A.
(2014).
Moderate intensity resistive exercise improves metaphyseal cancellous bone recovery following an initial disuse period, but does not mitigate decrements during a subsequent disuse period in adult rats. BONE.
66, 296-305.
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Boudreaux, R. D., Metzger, C. E., Macias, B. R., Shirazi-Fard, Y., Hogan, H. A., & Bloomfield, S. A.
(2014).
Bone loss during partial weight bearing (1/6th gravity) is mitigated by resistance and aerobic exercise in mice. Acta Astronautica.
99(1), 71-77.
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Boudreaux, R. D., Swift, J. M., Gasier, H. G., Wiggs, M. P., Hogan, H. A., Fluckey, J. D., & Bloomfield, S. A.
(2014).
Increased resistance during jump exercise does not enhance cortical bone formation. 46(5), 982-989.
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Ploutz-Snyder, L., Bloomfield, S., Smith, S. M., Hunter, S. K., Templeton, K., & Bemben, D.
(2014).
Effects of Sex and Gender on Adaptation to Space: Musculoskeletal Health. Journal of Women's Health.
23(11), 963-966.
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Swift, J. M., Lima, F., Macias, B. R., Allen, M. R., Greene, E. S., Shirazi-Fard, Y., ... Bloomfield, S. A.
(2013).
Partial weight bearing does not prevent musculoskeletal losses associated with disuse. 45(11), 2052-2060.
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Shirazi-Fard, Y., Anthony, R. A., Kwaczala, A. T., Judex, S., Bloomfield, S. A., & Hogan, H. A.
(2013).
Previous exposure to simulated microgravity does not exacerbate bone loss during subsequent exposure in the proximal tibia of adult rats. BONE.
56(2), 461-473.
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Swift, J. M., Hogan, H. A., & Bloomfield, S. A.
(2013).
-1 adrenergic agonist mitigates unloading-induced bone loss by maintaining formation. 45(9), 1665-1673.
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Shirazi-Fard, Y., Kupke, J. S., Bloomfield, S. A., & Hogan, H. A.
(2013).
Discordant recovery of bone mass and mechanical properties during prolonged recovery from disuse. BONE.
52(1), 433-443.
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Baek, K., & Bloomfield, S. A.
(2012).
Blocking -adrenergic signaling attenuates reductions in circulating leptin, cancellous bone mass, and marrow adiposity seen with dietary energy restriction. Journal of applied physiology.
113(11), 1792-1801.
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Kim, W. K., Bloomfield, S. A., Sugiyama, T., & Ricke, S. C.
(2012).
Concepts and methods for understanding bone metabolism in laying hens. 68(1), 71-82.
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Macias, B. R., Swift, J. M., Nilsson, M. I., Hogan, H. A., Bouse, S. D., & Bloomfield, S. A.
(2012).
Simulated resistance training, but not alendronate, increases cortical bone formation and suppresses sclerostin during disuse. 112(5), 918-925.
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Swift, S. N., Baek, K., Swift, J. M., & Bloomfield, S. A.
(2012).
Restriction of dietary energy intake has a greater impact on bone integrity than does restriction of calcium in exercising female rats. Journal of Nutrition.
142(6), 1038-1045.
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Swift, J. M., Swift, S. N., Nilsson, M. I., Hogan, H. A., Bouse, S. D., & Bloomfield, S. A.
(2011).
Cancellous bone formation response to simulated resistance training during disuse is blunted by concurrent alendronate treatment. Journal of Bone and Mineral Research.
26(9), 2140-2150.
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Kim, W. K., Bloomfield, S. A., & Ricke, S. C.
(2011).
Effects of age, vitamin D3, and fructooligosaccharides on bone growth and skeletal integrity of broiler chicks. 90(11), 2425-2432.
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Swift, J. M., Gasier, H. G., Swift, S. N., Wiggs, M. P., Hogan, H. A., Fluckey, J. D., & Bloomfield, S. A.
(2010).
Increased training loads do not magnify cancellous bone gains with rodent jump resistance exercise. 109(6), 1600-1607.
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Swift, J. M., Nilsson, M. I., Hogan, H. A., Sumner, L. R., & Bloomfield, S. A.
(2010).
Simulated resistance training during hindlimb unloading abolishes disuse bone loss and maintains muscle strength. 25(3), 564-574.
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Bloomfield, S. A.
(2010).
Disuse osteopenia. Current Osteoporosis Reports.
8(2), 91-97.
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Baek, K., & Bloomfield, S. A.
(2009).
Beta-adrenergic blockade and leptin replacement effectively mitigate disuse bone loss. Journal of Bone and Mineral Research.
24(5), 792-799.
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Prisby, R. D., Swift, J. M., Bloomfield, S. A., Hogan, H. A., & Delp, M. D.
(2008).
Altered bone mass, geometry and mechanical properties during the development and progression of type 2 diabetes in the Zucker diabetic fatty rat. 199(3), 379-388.
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Baek, K., Barlow, A. A., Allen, M. R., & Bloomfield, S. A.
(2008).
Food restriction and simulated microgravity: effects on bone and serum leptin. Journal of applied physiology.
104(4), 1086-1093.
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Kim, W. K., Donalson, L. M., Bloomfield, S. A., Hogan, H. A., Kubena, L. F., Nisbet, D. J., & Ricke, S. C.
(2007).
Molt performance and bone density of cortical, medullary, and cancellous bone in laying hens during feed restriction or alfalfa-based feed molt. 86(9), 1821-1830.
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Wallace, J. M., Rajachar, R. M., Allen, M. R., Bloomfield, S. A., Robey, P. G., Young, M. F., & Kohn, D. H.
(2007).
Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific. BONE.
40(4), 1120-1127.
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Bloomfield, S. A.
(2006).
Does altered blood flow to bone in microgravity impact on mechanotransduction?. 6(4), 324-326.
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Bloomfield, S. A.
(2006).
Summary - Bone in microgravity environments: "Houston, we have a problem". 6(4), 329-330.
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Allen, M. R., Hogan, H. A., & Bloomfield, S. A.
(2006).
Differential bone and muscle recovery following hindlimb unloading in skeletally mature male rats. 6(3), 217-225.
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Wallace, J. M., Rajachar, R. M., Chen, X., Shi, S., Allen, M. R., Bloomfield, S. A., ... Kohn, D. H.
(2006).
The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific. BONE.
39(1), 106-116.
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Bloomfield, S. A., Allen, M. R., Lemmon, H., & Hogan, H. A.
(2005).
Cancellous Bone Volume Is Restored By Intermittent PTH After Mechanical Unloading. 37(5), S342-S342.
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Hubal, M. J., Ingalls, C. P., Allen, M. R., Wenke, J. C., Hogan, H. A., & Bloomfield, S. A.
(2005).
Effects of eccentric exercise training on cortical bone and muscle strength in the estrogen-deficient mouse. Journal of applied physiology.
98(5), 1674-1681.
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Bloomfield, S. A.
(2005).
Contributions of physical activity to bone health over the lifespan. Topics in Geriatric Rehabilitation.
21(1), 68-76.
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Yao, Z., Lafage-Proust, M., Plout, J., Bloomfield, S., Alexandre, C., & Vico, L.
(2004).
Increase of both angiogenesis and bone mass in response to exercise depends on VEGF. Journal of Bone and Mineral Research.
19(9), 1471-1480.
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Kohrt, W. M., Bloomfield, S. A., Little, K. D., Nelson, M. E., Yingling, V. R., & American College of Sports Medicine.
(2004).
American College of Sports Medicine Position Stand: physical activity and bone health. Medicine & Science in Sports & Exercise.
36(11), 1985-1996.
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Narayanan, R., Allen, M. R., Gaddy, D., Bloomfield, S. A., Smith, C. L., & Weigel, N. L.
(2004).
Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089). BONE.
35(1), 134-143.
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Warren, G. L., Stallone, J. L., Allen, M. R., & Bloomfield, S. A.
(2004).
Functional recovery of the plantarflexor muscle group after hindlimb unloading in the rat. European Journal of Applied Physiology.
93(1-2), 130-138.
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Allen, M. R., & Bloomfield, S. A.
(2003).
Hindlimb unloading has a greater effect on cortical compared with cancellous bone in mature female rats. Journal of applied physiology.
94(2), 642-650.
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Mekraldi, S., Lafage-Proust, M., Bloomfield, S., Alexandre, C., & Vico, L.
(2003).
Changes in vasoactive factors associated with altered vessel morphology in the tibial metaphysis during ovariectomy-induced bone loss in rats. BONE.
32(6), 630-641.
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Bloomfield, S. A., Allen, M. R., Hogan, H. A., & Delp, M. D.
(2002).
Site- and compartment-specific changes in bone with hindlimb unloading in mature adult rats. 31(1), 149-157.
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Bloomfield, S. A., Hogan, H. A., & Delp, M. D.
(2002).
Decreases in bone blood flow and bone material properties in aging Fischer-344 rats. Clinical Orthopaedics and Related Research.
396(396), 248-257.
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Bloomfield, S. A.
(2001).
Cellular and molecular mechanisms for the bone response to mechanical loading. International Journal of Sport Nutrition and Exercise Metabolism.
11 Suppl(s1), S128-S136.
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Colleran, P. N., Wilkerson, M. K., Bloomfield, S. A., Suva, L. J., Turner, R. T., & Delp, M. D.
(2000).
Alterations in skeletal perfusion with simulated microgravity: a possible mechanism for bone remodeling. Journal of applied physiology.
89(3), 1046-1054.
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Schultheis, L., Ruff, C. B., Rastogi, S., Bloomfield, S., Hogan, H. A., Fedarko, N., ... Shapiro, J. R.
(2000).
Disuse bone loss in hindquarter suspended rats: partial weightbearing, exercise and ibandronate treatment as countermeasures. 7(2), P13-P14.
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Inman, C. L., Warren, G. L., Hogan, H. A., & Bloomfield, S. A.
(1999).
Mechanical loading attenuates bone loss due to immobilization and calcium deficiency. 87(1), 189-195.
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Turner, R. T., Wronski, T. J., Zhang, M., Kidder, L. S., Bloomfield, S. A., & Sibonga, J. D.
(1998).
Effects of ethanol on gene expression in rat bone: transient dose-dependent changes in mRNA levels for matrix proteins, skeletal growth factors, and cytokines are followed by reductions in bone formation. Alcoholism: Clinical and Experimental Research.
22(7), 1591-1599.
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Bloomfield, S. A., Girten, B. E., & Weisbrode, S. E.
(1997).
Effects of vigorous exercise training and beta-agonist administration on bone response to hindlimb suspension. Journal of applied physiology.
83(1), 172-178.
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Convertino, V. A., Bloomfield, S. A., & Greenleaf, J. E.
(1997).
An overview of the issues: physiological effects of bed rest and restricted physical activity. Medicine & Science in Sports & Exercise.
29(2), 187-190.
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Warren, G. L., Lowe, D. A., Inman, C. L., Orr, O. M., Hogan, H. A., Bloomfield, S. A., & Armstrong, R. B.
(1996).
Estradiol effect on anterior crural muscles-tibial bone relationship and susceptibility to injury. 80(5), 1660-1665.
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Bloomfield, S. A., Mysiw, W. J., & Jackson, R. D.
(1996).
Bone mass and endocrine adaptations to training in spinal cord injured individuals. BONE.
19(1), 61-68.
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Bloomfield, S. A., Jackson, R. D., & Mysiw, W. J.
(1994).
Catecholamine response to exercise and training in individuals with spinal cord injury. Medicine & Science in Sports & Exercise.
26(10), 1213-1219.
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Bloomfield, S. A., Williams, N. I., Lamb, D. R., & Jackson, R. D.
(1993).
Non-weightbearing exercise may increase lumbar spine bone mineral density in healthy postmenopausal women. American Journal of Physical Medicine and Rehabilitation.
72(4), 204-209.
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Sherman, W. M., Lash, J. M., Simonsen, J. C., & Bloomfield, S. A.
(1992).
Effects of downhill running on the responses to an oral glucose challenge. International journal of sport nutrition.
2(3), 251-259.
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Bloomfield, S., Girten, B., Weisbrode, S., Eveland, E., & Kazarian, L.
(1989).
Modifications of bone atrophy seen with hindlimb suspension by exercise and dobutamine. Physiologist.
32(1 Suppl), S27-S28.
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Ward, K. M., & Bloomfield, S. A.
(1987).
Clinical laboratory services in preventive, rehabilitative, and research-related exercise programs. Journal of medical technology : official publication of American Medical Technologists [and] American Society for Medical Technology.
1(1), 604-608.
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Martin, W. H., Coyle, E. F., Bloomfield, S. A., & Ehsani, A. A.
(1986).
Effects of physical deconditioning after intense endurance training on left ventricular dimensions and stroke volume. Journal of the American College of Cardiology.
7(5), 982-989.
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Ward, K. M., & Bloomfield, S. A.
(1986).
Clinical laboratory services in preventive, rehabilitative, and research-related exercise programs. Journal of medical technology : official publication of American Medical Technologists [and] American Society for Medical Technology.
3(12), 604-608.
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Coyle, E. F., Martin, W. H., Bloomfield, S. A., Lowry, O. H., & Holloszy, J. O.
(1985).
Effects of detraining on responses to submaximal exercise. Journal of applied physiology.
59(3), 853-859.
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Martin, W. H., Heath, G., Coyle, E. F., Bloomfield, S. A., Holloszy, J. O., & Ehsani, A. A.
(1984).
Effect of prolonged intense endurance training on systolic time intervals in patients with coronary artery disease. American Heart Journal.
107(1), 75-81.
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Heath, G. W., Gavin, J. R., Hinderliter, J. M., Hagberg, J. M., Bloomfield, S. A., & Holloszy, J. O.
(1983).
Effects of exercise and lack of exercise on glucose tolerance and insulin sensitivity. Journal of Applied Physiology.
55(2), 512-517.
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Coyle, E. F., Martin, W. H., Ehsani, A. A., Hagberg, J. M., Bloomfield, S. A., Sinacore, D. R., & Holloszy, J. O.
(1983).
Blood lactate threshold in some well-trained ischemic heart disease patients. Journal of Applied Physiology.
54(1), 18-23.
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Ehsani, A. A., Martin 3d, W. H., Heath, G. W., & Bloomfield, S. A.
(1982).
Left ventricular response to graded isometric exercise in patients with coronary heart disease. 2(3), 215-224.
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Gisolfi, C. V., Mora, F., Bloomfield, S., Beattie, M., & Magnes, S.
(1980).
Effects of apomorphine and pimozide on temperature regulation during exercise in the rat. Journal of Applied Physiology.
49(3), 363-366.
-
Wiggs, M. P., Lee, Y., Shimkus, K. L., O'Reilly, C. I., Lima, F., Macias, B. R., ... Fluckey, J. D.
(2023).
Combined effects of heavy ion exposure and simulated Lunar gravity on skeletal muscle. Life Sciences in Space Research.
37, 39-49.
-
chapter
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Bloomfield, S. A., & Metzger, C. E.
(2013).
Novel Findings in Bone Biology: Impact on Bone Health for Women. Integrative Biology of Womens Health.
(pp. 17-33).
Springer Nature.
-
Bloomfield, S. A., & Metzger, C. E.
(2013).
Novel Findings in Bone Biology: Impact on Bone Health for Women. Integrative Biology of Womens Health.
(pp. 17-33).
Springer Nature.
-
conference paper
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Little, S. E., Letsinger, A. C., Elizondo, J. P., Hogan, H. A., Lightfoot, J. T., & Bloomfield, S. A.
(2020).
EFFECTS OF DIET ALTERATIONS, WITH OR WITHOUT FECAL MICROBIAL TRANSPLANTS, ON BONE INTEGRITY. Medicine & Science in Sports & Exercise.
491-491.
-
Allaway, H. C., Elizondo, J. P., Little, S. E., Hogan, H. A., & Bloomfield, S. A.
(2020).
LARC Implant Use Does Not Exacerbate Bone Loss Associated With Hindlimb Unloading. Medicine & Science in Sports & Exercise.
73-74.
-
O'Reilly, C., Wiggs, M., Hogan, H., Bloomfield, S., & Fluckey, J.
(2020).
Combined Effects of Lunar Gravity and Heavy Ion Exposure on Skeletal Muscle Anabolic Signaling. The FASEB Journal.
1-1.
-
Little, S. E., Allaway, H., Bokhari, R. S., Seidel, D. V., Wahl, K. L., Turner, N. D., ... Bloomfield, S. A.
(2019).
Can Acute Galactic Cosmic Radiation-induced Bone Loss Be Mitigated By Dietary Modulation Of Inflammatory Cytokines?. Medicine & Science in Sports & Exercise.
406-406.
-
Allaway, H., Little, S. E., Hogan, H. A., & Bloomfield, S. A.
(2019).
Impact Of Long-acting Reversible Contraceptives On Bone Density During Simulated Microgravity. Medicine & Science in Sports & Exercise.
405-406.
-
Metzger, C. E., Narayanan, S. A., Anderson, A. M., Zaweija, D. C., & Bloomfield, S. A.
(2018).
Exogenous Irisin Treatment Ameliorates Inflammatory Changes in Osteocyte Proteins and Altered Bone Turnover in Chronic DSS-induced Inflammatory Bowel Disease. Journal of Bone and Mineral Research.
382-382.
-
Metzger, C. E., Junior, M., Brezicha, J. E., Hogan, H. A., & Bloomfield, S. A.
(2017).
Local Adaptations of Osteocyte Proteins to Increased and Decreased Mechanical Forces Correlate with Osteoblast Levels. Medicine & Science in Sports & Exercise.
394-395.
-
OReilly, C. L., Deaver, J. W., Wiggs, M. P., Lima, F., Swift, J. M., Greene, E. S., Bloomfield, S. A., & Fluckey, J. D.
(2017).
Partial or Complete Unloading of Skeletal Muscle Leads to Specific Alterations of Anabolic Signal Transduction. Medicine & Science in Sports & Exercise.
769-769.
-
Metzger, C. E., Gong, S., Aceves, M., Hook, M. A., & Bloomfield, S. A.
(2017).
Elevated osteocyte TNF-, IL-6, and sclerostin in a rodent model of spinal cord injury correlates with altered bone turnover. Journal of Bone and Mineral Research.
S239-S239.
-
Metzger, C. E., Brezicha, J. E., Lenfest, S. E., Hogan, H. A., & Bloomfield, S. A.
(2016).
Beyond Sclerostin: Influence of Disuse and Recovery from Disuse on Mechanosensitive Osteocyte Proteins. Medicine & Science in Sports & Exercise.
307-307.
-
Metzger, C. E., Swift, S., Baek, K., De Souza, M. J., & Bloomfield, S. A.
(2015).
Fat and Lean Mass Predict Total Body Bone Mineral Content during Energy Restriction with Exercise. Medicine & Science in Sports & Exercise.
414-414.
-
Metzger, C. E., Lee, T. V., McBurnett, P. K., Riechman, S. E., & Bloomfield, S. A.
(2014).
Does Osteocyte Sclerostin Response to Unloading and Exercise Vary across Bone Compartments?. Medicine & Science in Sports & Exercise.
39-39.
-
Shirazi-Fard, Y., Gonzalez, E., Morgan, D. S., Davis, J. M., Shimkus, K. L., Boudreaux, R. D., Bloomfield, S. A., & Hogan, H. A.
(2012).
BONE RESPONSE TO EXERCISE DURING RECOVERY BETWEEN UNLOADING BOUTS IN ADULT MALE RATS. 47-48.
-
Yuen, E., Morgan, J. L., Zwart, S. R., Gonzales, E., Camp, K., Macias, B. R., Smith, S. M., & Bloomfield, S. A.
(2012).
High dietary iron and 137Cs radiation exposure induce oxidative stress and reduce bone mass. The FASEB Journal.
-
Camp, K. A., Swift, S. N., Lima, F., Greene, E. S., De Souza, M. J., & Bloomfield, S. A.
(2012).
Is peak bone mass achieved following recovery from reduced energy availability?. The FASEB Journal.
-
Macias, B. R., Lima, F., Shirazi-Fard, Y., Wiggs, M. P., Fluckey, J. D., Greene, E. S., ... Bloomfield, S. A.
(2011).
Low dose X-ray but not silicon radiation exposure can exacerbate cancellous bone loss during partial weightbearing. BONE.
S175-S175.
-
Camp, K. A., Swift, S. N., Greene, E. S., Lima, F., & Bloomfield, S. A.
(2011).
Short-Term Reduction in Energy Availability Does Not Impair Exercise-Induced Gains in Bone Formation Rate. Medicine & Science in Sports & Exercise.
46-46.
-
Swift, J. M., Swift, S. N., Bouse, S. D., Hogan, H. A., & Bloomfield, S. A.
(2010).
Alendronate Inhibits Bone Formation Response To Simulated Resistance Training During Disuse. Medicine & Science in Sports & Exercise.
704-704.
-
Swift, S. N., Swift, J. M., Greene, E. S., De Souza, M. J., & Bloomfield, S. A.
(2010).
Energy Restriction Effects on Cancellous Bone Microarchitecture: Impact of Endurance Exercise. Medicine & Science in Sports & Exercise.
19-20.
-
Wiggs, M. P., Swift, J. M., Lima, F., Greene, E. S., Bloomfield, S. A., & Fluckey, J. D.
(2010).
The effect of simulated 1/6th and 1/3rd gravity on gastrocnemius muscle mass and fractional protein synthesis rates in mice. The FASEB Journal.
616.6-616.6.
-
Macias, B. R., Swift, J. M., Lima, F., Greene, E. S., Allen, M. R., & Bloomfield, S. A.
(2010).
Weightbearing In Simulated 1/6th and 1/3rd Gravity Does Not Prevent Cancellous Bone Loss. The FASEB Journal.
-
Bouse, S. D., Swift, J., Bloomfield, S. A., & Hogan, H. A.
(2009).
ANALYSIS OF IN VIVO STRAINS IN THE TIBIAL METAPHYSIS OF ADULT RATS DURING VOLUNTARY EXERCISING PROTOCOLS. 23-24.
-
Lucas, M. W., Swift, J. M., Shirazi-Fard, Y., Greene, E. S., Bloomfield, S. A., & Hogan, H. A.
(2009).
CHARACTERIZING STRAINS IN THE TIBIA OF HINDLIMB UNLOADED RATS DURING COMBINED ISOMETRIC AND ECCENTRIC STIMULATED MUSCLE CONTRACTION. 653-654.
-
Swift, S., Greene, E. S., De Souza, M. J., & Bloomfield, S. A.
(2009).
Thresholds for bone loss with energy restriction change with exercise status. The FASEB Journal.
-
Swift, J. M., Swift, S. N., & Bloomfield, S. A.
(2008).
Beta-Adrenergic Receptor Agonist Administration During Hindlimb Unloading Effectively Mitigates Reductions in Cancellous Bone Formation. Journal of Bone and Mineral Research.
S231-S231.
-
Hogan, H. A., Swift, J. M., Nilsson, M. I., & Bloomfield, S. A.
(2008).
Effects of Simulated Resistive Exercise on Cortical Bone in the Tibia Mid-Diapyhsis of Hindlimb Unloaded Rats. Journal of Bone and Mineral Research.
S232-S232.
-
Swift, S. N., Back, K., De Souza, M. J., & Bloomfield, S. A.
(2008).
Treadmill Exercise Provides Only Short-Term Protection Against Cancellous Bone Loss with Reduced Dietary Energy Intake: Endocrine Mechanisms. Journal of Bone and Mineral Research.
S218-S218.
-
Jeffery, J. M., Murphey, M. C., Stallone, J. L., Bloomfield, S. A., & Hogan, H. A.
(2007).
Characterizing strain in the tibia of rats exposed to hindlimb unloading with an exercise countermeasure. 909-910.
-
Swift, J. M., Ali, J. T., Stallone, J. L., Hogan, H. A., & Bloomfield, S. A.
(2007).
Beta-adrenergic receptor agonist administration during hindlimb unloading attenuates losses in bone geometry, structure, and mechanical properties. Journal of Bone and Mineral Research.
S134-S135.
-
Sumner, L. R., Nilsson, M. L., Swift, J. M., Jeffery, J. M., Walthall, C. J., Stallone, J. L., Bloomfield, S. A., & Hogan, H. A.
(2007).
Electrically stimulated eccentric muscle contraction benefits bone in the tibia of hindlimb unloaded rats at both the mid-diaphysis and proximal methaphysis. Journal of Bone and Mineral Research.
S488-S488.
-
Miller, S. N., Baek, K., Nilsson, M. I., Stallone, J. L., Lemmon, J., Hogan, H. A., & Bloomfield, S. A.
(2007).
Restricting dietary protein may improve skeletal integrity in exercising female rats. Journal of Bone and Mineral Research.
S321-S321.
-
Nilsson, M., Swift, J. M., Walthall, C. J., Stallone, J. L., Hogan, H. A., Fluckey, J. D., & Bloomfield, S. A.
(2007).
The effect of resistance exercise on in vivo-derived tomography measures and mechanical properties of rodent bone: Is more load always better?. Journal of Bone and Mineral Research.
S490-S490.
-
Hogan, H. A., Alcorn, J. D., Vyvial, B. A., & Bloomfield, S. A.
(2006).
Simulated resistive exercise benefits bone in hindlimb unloaded rats. Journal of Bone and Mineral Research.
S151-S151.
-
Hogan, H. A., Vyvial, B. A., Alcorn, J. D., Swift, J. M., Prisby, R. D., Bloomfield, S. A., & Delp, M. D.
(2005).
Alterations in the mechanical properties of bone due to Type II diabetes. Journal of Bone and Mineral Research.
S422-S422.
-
Baek, K., & Bloomfield, S. A.
(2005).
Beta-blockade mitigates bone loss with hindlimb unloading. Journal of Bone and Mineral Research.
S74-S74.
-
Kim, W. K., Donalson, L. M., Stallon, J. L., Bloomfield, S. A., Kubena, L. F., Nisbet, D. J., & Rickc, S. C.
(2005).
Effects of alfalfa based molt diets on cortical, cancellous and medullary bone qualities using pQCT. 131-131.
-
Swift, J. M., Allen, M. R., Hogan, H. A., & Bloomfield, S. A.
(2005).
Intermittent PTH Restores Cancellous BMD And Mechanical Properties During Recovery From Hindlimb Unloading. Medicine & Science in Sports & Exercise.
S150-S151.
-
Narayanan, R., Seng, C., Weigel, N. L., Bloomfield, S. A., & Smith, C. L.
(2004).
Attentuation of disuse-induced bone loss by estrogen and vitamin D receptor ligands in unloaded and ambulatory female rats. Journal of Bone and Mineral Research.
S482-S482.
-
Baek, K., Stallone, J. L., & Bloomfield, S. A.
(2004).
Beta-blockade mitigates bone loss with hindlimb unloading. The FASEB Journal.
A758-A758.
-
Bloomfield, S. A., Baek, K., Stallone, J. L., & Allen, M. R.
(2004).
Intermittent PTH during recovery replaces cancellous bone lost during hindlimb unloading by increasing bone formation rate. The FASEB Journal.
A691-A691.
-
Nielsen, K. L., Allen, M. R., Bloomfield, S. A., Andersen, T. L., Chen, X., Poulsen, H. S., Young, M. F., & Heegaard, A.
(2003).
Biglycan deficiency interferes with ovariectomy-induced bone loss. Journal of Bone and Mineral Research.
2152-2158.
-
Allen, M. R., & Bloomfield, S. A.
(2003).
Absence of mechanical load results in an attenuation of marrow ablation-induced increase in cancellous bone formation rate. Journal of Bone and Mineral Research.
S332-S332.
-
Sajid, M., Nolan, C., Allen, M. R., Bloomfield, S. A., & Smith, C. L.
(2003).
Changes in gene expression by estrogen receptor Ligands in the femora of Hindlimb unloaded male rats. Journal of Bone and Mineral Research.
S179-S179.
-
Baek, K., Currado, A., Allen, M. R., & Bloomfield, S. A.
(2003).
Comparison of serum leptin concentration under simulated microgravity condition or food restriction or combination of two. Journal of Bone and Mineral Research.
S333-S333.
-
Bloomfield, S. A., Allen, M. R., Lemmon, H., & Hogan, H. A.
(2003).
PTH replaces cancellous bone lost during 28 days of hindlimb unloading in skeletally mature rats. Journal of Bone and Mineral Research.
S11-S11.
-
Wallace, J. M., Rajacher, R. M., Chen, X., Shi, S., Allen, M. R., Bloomfield, S. A., Robey, P. G., & Young, M. F.
(2003).
Rescuing the phenotype of biglycan-deficient mice via exercise. Journal of Bone and Mineral Research.
S45-S45.
-
Song, W., Lawler, J. M., & Bloomfield, S. A.
(2003).
Hindlimb unloading increases iNOS protein expression and NF-kappaB DNA binding activity in rat skeletal muscle. The FASEB Journal.
A945-A945.
-
Chen, X., Allen, M. R., Bloomfield, S., Xu, T., & Young, M.
(2003).
Biglycan-deficient mice have delayed osteogenesis after marrow ablation. Calcified Tissue International.
577-582.
-
Wallace, J. M., Rajachar, R. M., Chen, X., Shi, S., Allen, M. R., Bloomfield, S. A., ... Kohn, D. H.
(2003).
Exercise Can Reverse the Phenotype of Biglycan Deficient Mice. American Society of Mechanical Engineerings, Bioengineering Division (Publication) BED.
37-38.
-
Bloomfield, S. A., Allen, M. R., Nolan, C., & Smith, C. L.
(2002).
Attenuation of disuse bone loss by estrogen and raloxifene in mature male rats. Journal of Bone and Mineral Research.
S433-S433.
-
Nielsen, K. L., Allen, M. R., Bloomfield, S. A., Timm, I. A., Chen, X. D., Young, M. F., & Heegaard, A.
(2002).
Biglycan deficiency interferes with ovariectomy-induced bone loss. Journal of Bone and Mineral Research.
S170-S170.
-
Allen, M. R., Hogan, H. A., & Bloomfield, S. A.
(2002).
Bone and muscle recovery after 28 days of hindlimb unloading in mature male rats. Journal of Bone and Mineral Research.
S434-S434.
-
Bloomfield, S. A.
(2001).
Cellular and molecular mechanisms for the bone response to mechanical loading. International journal of sport nutrition.
-
Hogan, H. A., Allen, M. R., Rogers, W. E., Weigel, N. L., & Bloomfield, S. A.
(2001).
1,25(OH)(2)D-3 and EB1089 produce higher femoral cancellous bone density after 28-d hindlimb unloading while only 1,25(OH)(2)D-3 enhances material properties. Journal of Bone and Mineral Research.
S484-S484.
-
Chen, X., Allen, M. R., Bloomfield, S. A., Xu, T., & Young, M. F.
(2001).
Biglycan deficient mice have delayed bone formation after bone marrow ablation. Journal of Bone and Mineral Research.
S450-S450.
-
Allen, M. R., Currado, A. C., & Bloomfield, S. A.
(2001).
Cancellous bone loss in adult rats following reduction in chow calcium and Vitamin D contents to NRC-recommended levels. Journal of Bone and Mineral Research.
S279-S279.
-
Narayanan, R., Allen, M. R., Stafinsky, J. L., Bloomfield, S. A., Smith, C. L., & Weigel, N. L.
(2001).
Effects of 1,25-(OH)2D3 and EB1089 on bone cells and bones of hindlimb unloaded adult male rats. Journal of Bone and Mineral Research.
S432-S432.
-
Allen, M. R., Stafinsky, J. L., Nolan, C., Bloomfield, S. A., & Smith, C. L.
(2001).
Raloxifene attenuates bone loss in mechanically unloaded, ovariectomized female rats. Journal of Bone and Mineral Research.
S414-S414.
-
Bloomfield, S. A., Allen, M. R., Zhang, M., & Turner, R. T.
(2001).
Greater deficit of bone formation in the mature adult rat with 28-d hindlimb unloading. The FASEB Journal.
A1113-A1113.
-
Allen, M. R., & Bloomfield, S. A.
(2001).
MATURE RAT SKELETAL CHANGES IN RESPONSE TO SIMULATED MIRCROGRAVITY: A GENDER COMPARISON. Medicine & Science in Sports & Exercise.
S299-S299.
-
Allen, M. R., Gordon, S. E., Davis, B., Fiorotto, M. L., Schwartz, R. J., Booth, F. W., & Bloomfield, S. A.
(2000).
Skeletal muscle IGF-I overexpression alters bone development and prevents short-term hindlimb unloading bone loss in adult mouse tibia. Journal of Bone and Mineral Research.
S368-S368.
-
Bloomfield, S. A.
(2000).
Cellular and molecular responses to altered loading of bone. JOURNAL OF AGING AND PHYSICAL ACTIVITY.
247-247.
-
Allen, M. R., Zhang, M., Turner, R. T., & Bloomfield, S. A.
(2000).
Short-term hind-limb unloading alters TGF-beta and cytokine gene expression in femur and humeri of rats. JOURNAL OF AGING AND PHYSICAL ACTIVITY.
276-277.
-
Allen, M. R., Ingalls, C. P., Warren, G. L., & Bloomfield, S. A.
(1999).
Time course of bone and muscle alterations after hindlimb suspension and 24-hour reambulation in mice. Journal of Bone and Mineral Research.
S217-S217.
-
Delp, M. D., Colleran, P. N., Wilkerson, M. K., Lorenz, E. P., Allen, M. R., Hogan, H. A., Suva, L. J., & Bloomfield, S. A.
(1999).
Short-term hindlimb unloading diminishes bone mineral density, area and blood flow in rats. Journal of Bone and Mineral Research.
S315-S315.
-
Bloomfield, S. A.
(1997).
Changes in musculoskeletal structure and function with prolonged bed rest. Medicine & Science in Sports & Exercise.
197-206.
-
BLOOMFIELD, S. A., WARREN, G. L., INMAN, C. L., & ARMSTRONG, R. B.
(1995).
EARLY ENZYME CHANGES IN MURINE TIBIAE AFTER HIGH-FORCE MUSCLE CONTRACTIONS. Journal of Bone and Mineral Research.
S409-S409.
-
Little, S. E., Letsinger, A. C., Elizondo, J. P., Hogan, H. A., Lightfoot, J. T., & Bloomfield, S. A.
(2020).
EFFECTS OF DIET ALTERATIONS, WITH OR WITHOUT FECAL MICROBIAL TRANSPLANTS, ON BONE INTEGRITY. Medicine & Science in Sports & Exercise.
491-491.
Research
principal investigator on
- Mitigating Radiation Induced Bone Loss via Dietary Modulation of Inflammatory Cytokines awarded by Johnson Space Center - (Houston, Texas, United States) 2016 - 2019
- Iron Overload and Oxidative Damage: Regulators of Bone Homeostasis in the Space Environment awarded by Ames Research Center - (Mountain View, California, United States) 2013 - 2018
- Sclerostin's role in regulating bone formation during long-term simulated microgravity and subsequent recovery- awarded by Johnson Space Center - (Houston, Texas, United States) 2014 - 2017
co-principal investigator on
- Inflamm-aging and bone loss in a rodent model of spinal cord injury awarded by Craig H Neilsen Foundation - (Los Angeles, California, United States) 2019 - 2021
- Retired Astronauts Medical Data Repository (RADAR): a Feasibility Project awarded by National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States) 2019 - 2020
- Pre-Treatment Approaches for Improving the Response of Bone to Disuse and Recovery - awarded by National Aeronautics and Space Administration - (Washington D.C., District of Columbia, United States) 2013 - 2018
Teaching
teaching activities
- KINE491 Research Instructor
- KINE681 Seminar Instructor
- KINE682 Hot Topics In Bone Biology Instructor
- KINE684 Prof Internship Instructor
- KINE685 Directed Studies Instructor
- KINE691 Research Instructor
- KINE691 Research Instructor
- MSCI691 Research Credit: Medical Sci Instructor
- NUEN681 Seminar Instructor
Works By Students
chaired theses and dissertations
-
Alcorn, Justin Dow (2007-09). Osteogenic effect of electric muscle stimulation as a countermeasure during hindlimb unloading.
-
Allen, Matthew Robert (2004-11). Mechanisms of impaired osteoblast function during disuse.
-
Baek, Kyunghwa (2009-05). Bone loss during energy restriction: mechanistic role of leptin.
-
Bokhari, Rihana (2018-07). Skeletal Impacts of Continuous Low-Dose-Rate Gamma Radiation Exposure During Simulated Microgravity.
-
Boudreaux, Ramon (2014-03). Sequential High-Impact, Free-Fall Loading and Zoledronic Acid as a Novel Pre-Treatment for Disuse-Induced Bone Loss.
-
Bouse, Scott (2010-07). Investigation of Transfer Function Analysis as a Means to Predict Strain on Rat Tibiae from Ankle Torque Waveforms.
-
Camp, Kaleigh Ann (2013-04). Impact of Omega-3 Polyunsaturated Fatty Acids on Bone Adaptations to Simulated Resistance Training.
-
Cunningham, David (2012-02). Ibuprofen Administered Pre- or Post- Simulated Resistance Exercise Training Does Not Diminsh Gains in Bone Formation or Bone Mass.
-
Davis, Joshua Morgan (2012-02). Characterization of the Bone Loss and Recovery Response at the Distal Femur Metaphysis of the Adult Male Hindlimb Unloaded Rat.
-
Gerges, Amira Sami (2005-02). Dietary calcium intake and overweight in adolescence.
-
Jeffery, Jay Melvin (2009-05). Quantifying the strain response in the rat tibia during simulated resistance training used as a disuse countermeasure.
-
Little, Sarah Elizabeth (2020-04). Dietary Modulation of Inflammation-Mediated Effects on Skeletal Biology.
-
Lucas, Matthew W. (2010-01). A Novel Method for the Evaluation of Mechanical Properties of Cancellous Bone in the Rat Distal Femur.
-
Macias, Brandon 1979- (2012-10). Bone Canonical WNT/B-Catenin Signaling in Models of Reduced Microgravity.
-
Marich, Alexandra Marie (2018-05). CONTINUOUS, LOW DOSE IRRADIATION RESULTS IN NO DETRIMENT TO BONE AFTER 4, 12, AND 28 DAYS.
-
Metzger, Corinne Elizabeth (2018-02). Inflammatory Bowel Disease and Bone: Mechanisms and Interventions for Inflammation-Induced Bone Alterations.
-
Miller, Sibyl Nichole 1980- (2009-05). Paradoxical effects of variant nutrients' restriction on bone health during a long-term aerobic exercise paradigm in female rats.
-
Shirazi-Fard, Yasaman (2013-04). Skeletal Response to Simulated Microgravity Exposures and Exercise in the Adult Rat Model.
-
Sumner, Lindsay Rebecca (2009-05). Osteogenic effect of optimized muscle stimulation exercise as a countermeasure during hindlimb unloading.
-
Swift, Joshua Michael (2011-08). Mitigating Disuse Bone Loss: Role of Resistance Exercise and Beta-Adrenergic Signaling.
-
Swift, Sibyl Nichole (2011-10). Energy Restriction Effects on Estrogen Status and the Skeletal Response to Loading.
-
Vyvial, Brent Aron (2007-09). Characterizing strain in the proximal rat tibia during electrical muscle stimulation.
-
Yuen, Evelyn P (2013-04). Effects of High Dietary Iron and Gamma Radiation on Oxidative Stress and Bone.
Background
education and training
- Ph.D. in Exercise Physiology, The Ohio State University - (Columbus, Ohio, United States) 1992
- M.A. in Physical Education, University of Iowa - (Iowa City, Iowa, United States) 1978
- B.A. in Biology, Oberlin College - (Oberlin, Ohio, United States) 1974
awards and honors
- Citation Award, conferred by American College of Sports Medicine - (Indianapolis, Indiana, United States), 2016
- Honor Award, conferred by American College of Sports Medicine - (Indianapolis, Indiana, United States), 2004
- Established Professional/Research Career Enhancement Awards, conferred by American Physiological Society - (Bethesda, Maryland, United States), 1997
Contact
first name
- Susan
has last name
- Bloomfield
mailing address
-
Texas A&M University
Health And Kinesiology
1113 TAMU
College Station, TX 77843-1113
USA
Other
- sbloom@tamu.edu