HR job title
- Associate Professor
- Contact Info
- 1 979 845 9180
Nabity, Mary Associate Professor
Positions
- Associate Professor, Veterinary Pathobiology, School of Veterinary Medicine and Biomedical Sciences
My research interests involve the pathogenesis of kidney disease and investigation of novel biomarkers in dogs and cats with chronic kidney disease and their relation to conventional measures of renal function. In our lab, we are actively exploring urinary proteins, mRNAs, and miRNAs in dogs with naturally occurring glomerular disease in order to determine their ability to serve as early markers of renal disease, specific markers of certain types of renal disease and disease progression, and targets for novel therapies. Our goal is to improve our understanding of the development and progression of kidney disease and to develop and validate testing methods in order to more effectively diagnosis and monitor renal disease in companion animals and humans.
Research Areas
- Overview
- Publications
- Research
- Teaching
- Background
- Contact
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Overview
Publications
selected publications
-
academic article
-
Grimes, M., Heseltine, J. C., Nabity, M. B., Lawhon, S. D., Wheeler, L., Cigarroa, A., & Lidbury, J. A.
(2020).
Characteristics associated with bacterial growth in urine in 451 proteinuric dogs (2008-2018). Journal of Veterinary Internal Medicine (JVIM).
34(2), 770-776.
-
Chu, C. P., Hokamp, J. A., Cianciolo, R. E., Dabney, A. R., Brinkmeyer-Langford, C., Lees, G. E., & Nabity, M. B.
(2020).
Author Correction: RNA-seq of serial kidney biopsies obtained during progression of chronic kidney disease from dogs with X-linked hereditary nephropathy. Scientific Reports.
10(1), 2381.
-
Zou, D., Ganugula, R., Arora, M., Nabity, M. B., Sheikh-Hamad, D., & Kumar, M.
(2019).
Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI. American Journal of Physiology: Renal Physiology.
317(5), F1255-F1264.
-
Rhode, H., Muckova, P., Bchler, R., Wendler, S., Tautkus, B., Vogel, M., ... Nabity, M.
(2019).
A next generation setup for pre-fractionation of non-denatured proteins reveals diverse albumin proteoforms each carrying several post-translational modifications. Scientific Reports.
9(1), 11733.
-
Chu, C. P., & Nabity, M. B.
(2019).
Comparison of RNA isolation and library preparation methods for small RNA sequencing of canine biofluids. Veterinary Clinical Pathology.
48(2), 310-319.
-
Boyd, C. J., Claus, M. A., Raisis, A. L., Cianciolo, R., Bosio, E., Hosgood, G., ... Smart, L.
(2019).
Evaluation of biomarkers of kidney injury following 4% succinylated gelatin and 6% hydroxyethyl starch 130/0.4 administration in a canine hemorrhagic shock model. Journal of Veterinary Emergency and Critical Care.
29(2), 132-142.
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Clark, S. D., Song, W., Cianciolo, R., Lees, G., Nabity, M., & Liu, S.
(2019).
Abnormal Expression of miR-21 in Kidney Tissue of Dogs With X-Linked Hereditary Nephropathy: A Canine Model of Chronic Kidney Disease. Veterinary Pathology.
56(1), 93-105.
-
Hernandez, A. M., Bilbrough, G., DeNicola, D. B., Myrick, C., Edwards, S., Hammond, J. M., ... Nabity, M. B.
(2019).
Comparison of the performance of the IDEXX SediVue Dx with manual microscopy for the detection of cells and 2 crystal types in canine and feline urine. JOURNAL OF VETERINARY INTERNAL MEDICINE.
33(1), 167-177.
-
Nabity, M. B., Polli, J. W., Vaidya, V., Krolewski, A., & Glaab, W. E.
(2018).
New Frontiers: Approaches to Understand the Mechanistic Basis of Renal Toxicity. Toxicologic Pathology.
46(8), 1002-1005.
-
Nabity, M. B.
(2018).
Traditional Renal Biomarkers and New Approaches to Diagnostics. Toxicologic Pathology.
46(8), 999-1001.
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Hokamp, J. A., Leidy, S. A., Gaynanova, I., Cianciolo, R. E., & Nabity, M. B.
(2018).
Correlation of electrophoretic urine protein banding patterns with severity of renal damage in dogs with proteinuric chronic kidney disease. Veterinary Clinical Pathology.
47(3), 425-434.
-
Parambeth, J. C., Hernandez, A. M., Nabity, M. B., Russell, K. E., Myers, A. N., Puchot, M. L., Creevy, K. E., & Lidbury, J. A.
(2018).
What is your diagnosis? Unusual urinary crystals from a cat. Veterinary Clinical Pathology.
47(3), 507-508.
-
Heilmann, R. M., Grtzner, N., Hokamp, J. A., Lidbury, J. A., Xenoulis, P. G., Suchodolski, J. S., ... Steiner, J. M.
(2018).
Serum 1-proteinase inhibitor concentrations in dogs with exocrine pancreatic disease, chronic hepatitis or proteinuric chronic kidney disease. The Veterinary Journal.
236, 68-71.
-
Nabity, M. B., Harr, K. E., Camus, M. S., Flatland, B., & Vap, L. M.
(2018).
ASVCP guidelines: Allowable total error hematology. Veterinary Clinical Pathology.
47(1), 9-21.
-
Brinkmeyer-Langford, C., Chu, C., Balog-Alvarez, C., Yu, X., Cai, J. J., Nabity, M., & Kornegay, J. N.
(2018).
Expression profiling of disease progression in canine model of Duchenne muscular dystrophy. PLoS ONE.
13(3), e0194485-e0194485.
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Curtis-Robles, R., Auckland, L. D., Hodo, C. L., Snowden, K. F., Nabity, M. B., & Hamer, S. A.
(2018).
Trypanosoma cruzi discrete typing unit TcIV implicated in a case of acute disseminated canine Chagas disease. Veterinary Parasitology: Regional Studies and Reports.
12, 85-88.
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Chu, C. P., Hokamp, J. A., Cianciolo, R. E., Dabney, A. R., Brinkmeyer-Langford, C., Lees, G. E., & Nabity, M. B.
(2017).
RNA-seq of serial kidney biopsies obtained during progression of chronic kidney disease from dogs with X-linked hereditary nephropathy. 7(1), 16776.
-
Martnez-Jimnez, D., Garner, B., Coutermarsh-Ott, S., Burrell, C., Clark, S., Nabity, M., ... Cazzini, P.
(2017).
Eosinophilic leukemia in three African pygmy hedgehogs ( Atelerix albiventris) and validation of Luna stain. Journal of Veterinary Diagnostic Investigation.
29(2), 217-223.
-
Clark, S. D., Nabity, M. B., Cianciolo, R. E., Dufek, B., & Cosgrove, D.
(2016).
X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage. PLoS ONE.
11(12), e0168343-e0168343.
-
Cianciolo, R., Hokamp, J., & Nabity, M.
(2016).
Advances in the evaluation of canine renal disease. 215, 21-29.
-
Minard, H. M., Burrell, C., Delgado, J. D., Rech, R. R., & Nabity, M. B.
(2016).
What's your diagnosis? Skin impression smear from a Bearded Dragon. Veterinary Clinical Pathology.
45(3), 505-506.
-
Benali, S. L., Lees, G. E., Nabity, M. B., Aric, A., Drigo, M., Gallo, E., Giantin, M., & Aresu, L.
(2016).
X-Linked Hereditary Nephropathy in Navasota Dogs: Clinical Pathology, Morphology, and Gene Expression During Disease Progression. Veterinary Pathology.
53(4), 803-812.
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Davis, J., Raisis, A. L., Cianciolo, R. E., Miller, D. W., Shiel, R. E., Nabity, M. B., & Hosgood, G. L.
(2016).
Urinary neutrophil gelatinase-associated lipocalin concentration changes after acute haemorrhage and colloid-mediated reperfusion in anaesthetized dogs. 43(3), 262-270.
-
Hokamp, J. A., & Nabity, M. B.
(2016).
Renal biomarkers in domestic species. 45(1), 28-56.
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Hokamp, J. A., Cianciolo, R. E., Boggess, M., Lees, G. E., Benali, S. L., Kovarsky, M., & Nabity, M. B.
(2016).
Correlation of Urine and Serum Biomarkers with Renal Damage and Survival in Dogs with Naturally Occurring Proteinuric Chronic Kidney Disease. 30(2), 591-601.
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Cowgill, L. D., Polzin, D. J., Elliott, J., Nabity, M. B., Segev, G., Grauer, G. F., ... van Dongen, A. M.
(2016).
Is Progressive Chronic Kidney Disease a Slow Acute Kidney Injury?. Veterinary Clinics of North America - Small Animal Practice.
46(6), 995-1013.
-
Nabity, M. B., Lees, G. E., Boggess, M. M., Yerramilli, M., Obare, E., Yerramilli, M., ... Relford, R.
(2015).
Symmetric Dimethylarginine Assay Validation, Stability, and Evaluation as a Marker for the Early Detection of Chronic Kidney Disease in Dogs. 29(4), 1036-1044.
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Weir, H., Chen, P. L., Deiss, T. C., Jacobs, N., Nabity, M. B., Young, M., & Criscitiello, M. F.
(2015).
DNP-KLH Yields Changes in Leukocyte Populations and Immunoglobulin Isotype Use with Different Immunization Routes in Zebrafish. Frontiers in Immunology.
6(DEC), 606.
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Harr, K. E., Flatland, B., Nabity, M., Freeman, K. P., & ASVCP.
(2013).
ASVCP guidelines: allowable total error guidelines for biochemistry. Veterinary Clinical Pathology.
42(4), 424-436.
-
Kvitko-White, H. L., Cook, A. K., Nabity, M. B., Zhang, S., & Lawhon, S. D.
(2013).
Evaluation of a catalase-based urine test for the detection of urinary tract infection in dogs and cats. Journal of Veterinary Internal Medicine (JVIM).
27(6), 1379-1384.
-
Brown, M. R., Cianciolo, R. E., Nabity, M. B., Brown, C. A., Clubb, F. J., & Lees, G. E.
(2013).
Masitinib-associated minimal change disease with acute tubular necrosis resulting in acute kidney injury in a dog. Journal of Veterinary Internal Medicine (JVIM).
27(6), 1622-1626.
-
Nabity, M. B., Lees, G. E., Boggess, M., Yerramilli, M., Obare, E., Yerramilli, M., Aguiar, J., & Relford, R.
(2013).
CORRELATION OF SYMMETRIC DIMETHYLARGININE WITH GLOMERULAR FILTRATION RATE IN DOGS WITH CHRONIC PROGRESSIVE RENAL DISEASE. Journal of Veterinary Internal Medicine (JVIM).
27(3), 733-733.
-
Benali, S. L., Lees, G. E., Nabity, M. B., Mantovani, R., Bonsembiante, F., & Aresu, L.
(2013).
De novo expression of human leukocyte antigen-DR (HLA-DR) and loss of beta-catenin expression in tubular epithelial cells: a possible event in epithelial-mesenchymal transition in canine renal diseases. The Veterinary Journal.
198(1), 229-234.
-
Schneider, S. M., Cianciolo, R. E., Nabity, M. B., Clubb, F. J., Brown, C. A., & Lees, G. E.
(2013).
Prevalence of immune-complex glomerulonephritides in dogs biopsied for suspected glomerular disease: 501 cases (2007-2012). Journal of Veterinary Internal Medicine (JVIM).
27 Suppl 1(S1), S67-S75.
-
Nabity, M. B., Lees, G. E., Boggess, M., Yerramilli, M., Obare, E., Yerramilli, M., Aguiar, J., & Relford, R.
(2013).
WEEK-TO-WEEK VARIABILITY OF IOHEXOL CLEARANCE, SERUM CREATININE, AND SYMMETRIC DIMETHYLARGININE IN DOGS WITH STABLE CHRONIC RENAL DISEASE. Journal of Veterinary Internal Medicine (JVIM).
27(3), 734-734.
-
Cooper, T. K., Zhong, Q., Nabity, M., Rosenberg, G., & Weiss, W. J.
(2012).
Use of urinary biomarkers of renal ischemia in a lamb preclinical left ventricular assist device model. Artificial Organs.
36(9), 820-824.
-
Nowend, K. L., Starr-Moss, A. N., Lees, G. E., Berridge, B. R., Clubb, F. J., Kashtan, C. E., Nabity, M. B., & Murphy, K. E.
(2012).
Characterization of the genetic basis for autosomal recessive hereditary nephropathy in the English Springer Spaniel. Journal of Veterinary Internal Medicine (JVIM).
26(2), 294-301.
-
Nabity, M. B., Lees, G. E., Cianciolo, R., Boggess, M. M., Steiner, J. M., & Suchodolski, J. S.
(2012).
Urinary biomarkers of renal disease in dogs with X-linked hereditary nephropathy. Journal of Veterinary Internal Medicine (JVIM).
26(2), 282-293.
-
Backlund, B., Zoran, D. L., Nabity, M. B., Norby, B. o., & Bauer, J. E.
(2011).
Effects of dietary protein content on renal parameters in normal cats. Journal of Feline Medicine and Surgery.
13(10), 698-704.
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Nabity, M. B., Lees, G. E., Dangott, L. J., Cianciolo, R., Suchodolski, J. S., & Steiner, J. M.
(2011).
Proteomic analysis of urine from male dogs during early stages of tubulointerstitial injury in a canine model of progressive glomerular disease. Veterinary Clinical Pathology.
40(2), 222-236.
-
Ralph, A. G., Saunders, A. B., Hariu, C. D., & Nabity, M.
(2011).
Spontaneous echocardiographic contrast in three dogs. Journal of Veterinary Emergency and Critical Care.
21(2), 158-165.
-
Daly, M., Sheppard, S., Cohen, N., Nabity, M., Moussy, A., Hermine, O., & Wilson, H.
(2011).
Safety of masitinib mesylate in healthy cats. Journal of Veterinary Internal Medicine (JVIM).
25(2), 297-302.
-
Nabity, M. B.
(2011).
Re-evaluating urine dipstick protein in dogs: when should you be concerned?. Advances in Small Animal Medicine and Surgery.
24(11), 1-3.
-
Nabity, M. B., Brock, R., Brown, J. S., Cianciolo, R., Hunter, C., & Lees, G. E.
(2010).
COMPARISON OF URINE SODIUM DODECYL SULFATE-POLYACRYLAMIDE GEL ELECTROPHORESIS (SDS-PAGE) WITH RENAL HISTOLOGIC FINDINGS IN DOGS WITH RENAL DISEASE. Journal of Veterinary Internal Medicine (JVIM).
24(3), 769-769.
-
Backlund, B., Zoran, D. L., Bauer, J. E., Nabity, M. B., & Norby, B.
(2010).
EFFECTS OF THE LEVEL OF DIETARY PROTEIN ON RENAL INDICES IN NORMAL ADULT CATS. Journal of Veterinary Internal Medicine (JVIM).
24(3), 774-774.
-
Nabity, M. B., Lees, G. E., Steiner, J. M., & Suchodolski, J. S.
(2010).
SURFACE ENHANCED LASER DESORPTION IONIZATION (SELDI) ANALYSIS OF URINE FROM MALE DOGS IN EARLY STAGES OF PROGRESSIVE TUBULOINTERSTITIAL INJURY DUE TO X-LINKED HEREDITARY NEPHROPATHY. Journal of Veterinary Internal Medicine (JVIM).
24(3), 770-770.
-
Stacy, N. I., Nabity, M. B., Hackendahl, N., Buote, M., Ward, J., Ginn, P. E., ... Harvey, J. W.
(2009).
B-cell lymphoma with Mott cell differentiation in two young adult dogs. Veterinary Clinical Pathology.
38(1), 113-120.
-
Chapman, S., Nabity, M., & Calise, D.
(2008).
What is your diagnosis? Lingual mass in a dog. Veterinary Clinical Pathology.
37(1), 133-139.
-
Chapman, S., Pittman, J., Nabity, M., & Johnson, M.
(2008).
Sodium hypochlorite bleach ingestion in two dogs. VETERINARY MEDICINE.
103(1), 13-18.
-
Nabity, M. B., Boggess, M. M., Kashtan, C. E., & Lees, G. E.
(2007).
Day-to-Day variation of the urine protein: creatinine ratio in female dogs with stable glomerular proteinuria caused by X-linked hereditary nephropathy. Journal of Veterinary Internal Medicine (JVIM).
21(3), 425-430.
-
Nabity, M. B., Barnhart, K., Logan, K. S., Santos, R. L., Kessell, A., Melmed, C., & Snowden, K. F.
(2006).
An atypical case of Trypanosoma cruzi infection in a young English Mastiff. Veterinary Parasitology.
140(3-4), 356-361.
-
Grimes, M., Heseltine, J. C., Nabity, M. B., Lawhon, S. D., Wheeler, L., Cigarroa, A., & Lidbury, J. A.
(2020).
Characteristics associated with bacterial growth in urine in 451 proteinuric dogs (2008-2018). Journal of Veterinary Internal Medicine (JVIM).
34(2), 770-776.
-
chapter
-
Clark, S. D., & Nabity, M. B.
(2020).
24 Male Reproductive Tract Prostate, Testes, Penis, and Semen. Cowell and Tyler's Diagnostic Cytology and Hematology of the Dog and Cat.
(pp. 406-422).
Elsevier.
-
Nabity, M. B., & Ramaiah, S. K.
(2012).
Blood and bone marrow toxicity. VETERINARY TOXICOLOGY: BASIC AND CLINICAL PRINCIPLES, 2ND EDITION.
(pp. 351-363).
Elsevier.
-
Nabity, M. B., & Ramaiah, S. K.
(2012).
Chapter 22 Blood and bone marrow toxicity. Veterinary Toxicology.
(pp. 351-363).
Elsevier.
-
Nabity, M. B.
(2011).
Urine protein and microalbuminuria. NEPHROLOGY AND UROLOGY OF SMALL ANIMALS.
(pp. 58-61).
Wiley.
-
Ramaiah, S. K., & Nabity, M. B.
(2007).
Blood and bone marrow toxicity. VETERINARY TOXICOLOGY: BASIC AND CLINICAL PRINCIPLES.
(pp. 277-288).
Elsevier.
-
Ramaiah, S. K., & Nabity, M. B.
(2007).
Chapter 17 Blood and bone marrow toxicity. Veterinary Toxicology.
(pp. 277-v).
Elsevier.
-
Clark, S. D., & Nabity, M. B.
(2020).
24 Male Reproductive Tract Prostate, Testes, Penis, and Semen. Cowell and Tyler's Diagnostic Cytology and Hematology of the Dog and Cat.
(pp. 406-422).
Elsevier.
Research
principal investigator on
- MicroRNA profiling in dogs with chronic kidney disease caused by glomerular diseases awarded by American Kennel Club Canine Health Foundation - (Raleigh, North Carolina, United States) 2015 - 2018
- Investigation of microRNAs as non-invasive biomarkers of chronic kidney disease in dogs awarded by American Kennel Club Canine Health Foundation - (Raleigh, North Carolina, United States) 2014 - 2018
- Urinary protein and gene expression characterization and comparison with renal biopsy findings and clinical data in dogs with proteinuric renal diseases awarded by American Kennel Club Canine Health Foundation - (Raleigh, North Carolina, United States) 2012 - 2014
- Correlation of urine biomarkers with chronic renal disease progression in dogs awarded by Morris Animal Foundation - (Denver, Colorado, United States) 2007 - 2010
investigator on
- FDA Vet-LIRN Site Application –Agrilife and the Texas A&M University System awarded by United States Food and Drug Administration - (Silver Spring, Maryland, United States) 2017 - 2022
- AAV2- CRiSPR/Cas9 preclinical trial on a naturally occurring ATS dog model awarded by Alport Syndrome Foundation - (Phoenix, Arizona, United States) 2018 - 2021
- Characterization of Renal Disease in American Boxer Dogs awarded by American Kennel Club Canine Health Foundation - (Raleigh, North Carolina, United States) 2018 - 2021
- Characterization of Kidney Disease in Dalmatians awarded by American Kennel Club Canine Health Foundation - (Raleigh, North Carolina, United States) 2016 - 2020
Teaching
teaching activities
- BIMS491 Research Instructor
- VPAT640 Advanced Mechanisms Of Disease Instructor
- VPAT640 Mechanisms Of Disease Instructor
- VPAT685 Directed Studies Instructor
- VPAT691 Research Instructor
- VTMI685 Directed Studies Instructor
- VTMI691 Research Instructor
- VTPB285 Directed Studies Instructor
- VTPB485 Directed Studies Instructor
Background
education and training
- Ph.D. in Veterinary Pathology, Texas A&M University - (College Station, Texas, United States) 2010
- D.V.M. in Veterinary Medicine, Cornell University - (Ithaca, New York, United States) 2002
- B.S. in Biochemistry, University of Nebraska–Lincoln - (Lincoln, United States) 1998
Contact
first name
- Mary
has last name
- Nabity
mailing address
-
Texas A&M University
Vet Med Pathobiology
4467 TAMU
College Station, TX 77843-4467
USA
Other
- mnabity@tamu.edu