HR job title
- Professor
- Contact Info
- Websites
- ORCiD
- 0000-0002-9701-5422
Shireman, Paula Professor
Positions
- Professor, Primary Care & Rural Medicine, Texas A&M University Naresh K. Vashisht College of Medicine, Health Science Center
- Professor, Medical Physiology, Texas A&M University Naresh K. Vashisht College of Medicine
Dr. Shireman is a Professor in the TAMU College of Medicine. She is board certified in vascular surgery, general surgery, wound care and clinical informatics. She is the PI of a pilot clinical trial with the College of Engineering on establishing artificial intelligence algorithms to monitor activities of daily living (ADL) in elderly subjects. Potential applications include aging in place, improved monitoring in healthcare/assisted living institutions and remote monitoring.
She was the PI of an NIH multicenter U01 grant developing predictive models for surgical outcomes including frailty and social risk factors. The goal is to use data to transform health care, influence federal policy and design financially sustainable care pathways improving outcomes for frail and low socioeconomic status patients.
Her interests include predictive modeling, machine learning, developing aging in place technologies, Health Digital Twins for clinical decision support and simulation. She was a member of the MACRA Episode-Based Cost Measure Clinical Subcommittee to develop measures for Peripheral Vascular Disease Management and Chair of the Clinical Subcommittee Workgroup for Hemodialysis Access Creation.
Her bench-based research interests include wound healing, especially for diabetic foot ulcers and burn wounds, and developing technologies to monitor wound healing.
She was the PI of an NIH multicenter U01 grant developing predictive models for surgical outcomes including frailty and social risk factors. The goal is to use data to transform health care, influence federal policy and design financially sustainable care pathways improving outcomes for frail and low socioeconomic status patients.
Her interests include predictive modeling, machine learning, developing aging in place technologies, Health Digital Twins for clinical decision support and simulation. She was a member of the MACRA Episode-Based Cost Measure Clinical Subcommittee to develop measures for Peripheral Vascular Disease Management and Chair of the Clinical Subcommittee Workgroup for Hemodialysis Access Creation.
Her bench-based research interests include wound healing, especially for diabetic foot ulcers and burn wounds, and developing technologies to monitor wound healing.
Research Areas
- Overview
- Publications
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Overview
Publications
selected publications
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academic article
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Schmidt, S., Jacobs, M. A., Kim, J., Hall, D. E., Stitzenberg, K. B., Kao, L. S., ... Shireman, P. K.
(2024).
Presentation Acuity and Surgical Outcomes for Patients With Health Insurance Living in Highly Deprived Neighborhoods. JAMA Surgery.
159(4), 411-419.
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Jacobs, M. A., Schmidt, S., Hall, D. E., Stitzenberg, K. B., Kao, L. S., Brimhall, B. B., ... Shireman, P. K.
(2024).
A Surgical Desirability of Outcome Ranking (DOOR) Reveals Complex Relationships Between Race/Ethnicity, Insurance Type, and Neighborhood Deprivation. ANNALS OF SURGERY.
279(2), 246-257.
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Craven, C. K., Highfield, L., Basit, M., Bernstam, E. V., Choi, B. Y., Ferrer, R. L., ... Schmidt, S.
(2024).
Erratum: Toward standardization, harmonization, and integration of social determinants of health data: A Texas Clinical and Translational Science Award institutions collaboration - CORRIGENDUM. Journal of Clinical and Translational Science.
8(1), e62.
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Craven, C. K., Highfield, L., Basit, M., Bernstam, E. V., Choi, B. Y., Ferrer, R. L., ... Schmidt, S.
(2024).
Towards Standardization, Harmonization, and Integration of Social Determinants of Health Data: A Texas Clinical and Translational Science Award Institutions Collaboration. 8(1), 1-34.
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Jacobs, M. A., Schmidt, S., Hall, D. E., Stitzenberg, K. B., Kao, L. S., Wang, C., Manuel, L. S., & Shireman, P. K.
(2023).
Differentiating Urgent from Elective Cases Matters in Minority Populations: Developing an Ordinal "Desirability of Outcome Ranking" to Increase Granularity and Sensitivity of Surgical Outcomes Assessment. Journal of the American College of Surgeons.
237(3), 545-555.
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Jacobs, M. A., Tetley, J. C., Kim, J., Schmidt, S., Brimhall, B. B., Mika, V., ... Shireman, P. K.
(2023).
Association of Cumulative Colorectal Surgery Hospital Costs, Readmissions, and Emergency Department/Observation Stays with Insurance Type. Journal of Gastrointestinal Surgery.
27(5), 965-979.
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Jacobs, M. A., Kim, J., Tetley, J. C., Schmidt, S., Brimhall, B. B., Mika, V., ... Shireman, P. K.
(2023).
Association of Insurance Type with Inpatient Surgical 30-day Readmissions, Emergency Department Visits/Observation Stays, and Costs. 4(1), e235-e235.
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Schmidt, S., Kim, J., Jacobs, M. A., Hall, D. E., Stitzenberg, K. B., Kao, L. S., ... Shireman, P. K.
(2023).
Independent Associations of Neighborhood Deprivation and Patient-level Social Determinants of Health with Textbook Outcomes after Inpatient Surgery. 4(1), e237-e237.
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Yan, Q. i., Kim, J., Hall, D. E., Shinall, M. C., Reitz, K. M., Stitzenberg, K. B., ... Shireman, P. K.
(2023).
Association of Frailty and the Expanded Operative Stress Score with Preoperative Acute Serious Conditions, Complications, and Mortality in Males Compared to Females: A Retrospective Observational Study. ANNALS OF SURGERY.
277(2), e294-e304.
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Simon, R. C., Kim, J., Schmidt, S., Brimhall, B. B., Salazar, C. I., Wang, C., ... Shireman, P. K.
(2023).
Association of Insurance Type With Inpatient Surgery 30-Day Complications and Costs. Journal of Surgical Research.
282, 22-33.
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Jacobs, M. A., Kim, J., Tetley, J. C., Schmidt, S., Brimhall, B. B., Mika, V., ... Shireman, P. K.
(2023).
Cost of Failure to Achieve Textbook Outcomes: Association of Insurance Type with Outcomes and Cumulative Cost for Inpatient Surgery. Journal of the American College of Surgeons.
236(2), 352-364.
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Yan, Q. i., Kim, J., Hall, D. E., Shinall, M. C., Reitz, K. M., Stitzenberg, K. B., ... Shireman, P. K.
(2023).
Sex-Related Differences in Acuity and Postoperative Complications, Mortality and Failure to Rescue. Journal of Surgical Research.
282, 34-46.
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Kim, J., Jacobs, M. A., Schmidt, S., Brimhall, B. B., Salazar, C. I., Wang, C., ... Shireman, P. K.
(2022).
Retrospective cohort study comparing surgical inpatient charges, total costs, and variable costs as hospital cost savings measures. Medicine.
101(50), e32037-e32037.
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Tetley, J. C., Jacobs, M. A., Kim, J., Schmidt, S., Brimhall, B. B., Mika, V., ... Shireman, P. K.
(2022).
Association of Insurance Type With Colorectal Surgery Outcomes and Costs at a Safety-Net Hospital: A Retrospective Observational Study. 3(4), e215-e215.
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Li, S. R., Reitz, K. M., Kennedy, J., Gabriel, L., Phillips, A. R., Shireman, P. K., Eslami, M. H., & Tzeng, E.
(2022).
Epidemiology of age-, sex-, and race-specific hospitalizations for abdominal aortic aneurysms highlights gaps in current screening recommendations. Journal of Vascular Surgery.
76(5), 1216-1226.e4.
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Copeland, L. A., Pugh, M. J., Bollinger, M. J., Wang, C., Amuan, M. E., Rivera, J. C., & Shireman, P. K.
(2022).
The VA vascular injury study: A glimpse at quality of care in Veterans with traumatic vascular injury repair. Injury.
53(6), 1947-1953.
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Fedorova, E., Zhang, G. Q., Shireman, P. K., Woo, K., & Hicks, C. W.
(2022).
Association of preoperative vein mapping with hemodialysis access characteristics and outcomes in the Vascular Quality Initiative. Journal of Vascular Surgery.
75(4), 1395-1402.e5.
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George, E. L., Massarweh, N. N., Youk, A., Reitz, K. M., Shinall, M. C., Chen, R., ... Hall, D. E.
(2022).
Comparing Veterans Affairs and Private Sector Perioperative Outcomes After Noncardiac Surgery. JAMA Surgery.
157(3), 231-239.
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Bernstam, E. V., Shireman, P. K., Meric-Bernstam, F., N Zozus, M., Jiang, X., Brimhall, B. B., ... Becich, M. J.
(2022).
Artificial intelligence in clinical and translational science: Successes, challenges and opportunities. Clinical and Translational Science.
15(2), 309-321.
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Reitz, K. M., Althouse, A. D., Meyer, J., Arya, S., Goodney, P. P., Shireman, P. K., Hall, D. E., & Tzeng, E.
(2022).
Association of Smoking With Postprocedural Complications Following Open and Endovascular Interventions for Intermittent Claudication. JAMA Cardiology.
7(1), 45-54.
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Fischer, U. M., Shireman, P. K., & Lin, J. C.
(2021).
Current applications of artificial intelligence in vascular surgery. Seminars in Vascular Surgery.
34(4), 268-271.
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Reitz, K. M., Hall, D. E., Shinall, M. C., Shireman, P. K., & Silverstein, J. C.
(2021).
Using the Unified Medical Language System to Expand the Operative Stress Score - First Use Case. Journal of Surgical Research.
268, 552-561.
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Hicks, C. W., Vavra, A. K., Goldsborough, E., Rebuffatti, M., Almeida, J., Duwayri, Y. M., ... Woo, K.
(2021).
Current status of patient-reported outcome measures in vascular surgery. Journal of Vascular Surgery.
74(5), 1693-1706.e1.
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Sorber, R., Canner, J. K., Abularrage, C. J., Shireman, P. K., Segev, D. L., Black Iii, J. H., Woo, K., & Hicks, C. W.
(2021).
Quantifying The Costs of Creating and Maintaining Hemodialysis Access in An All-Payer Rate-Controlled Health System. Annals of Vascular Surgery: international journal of vascular surgery.
76, 142-151.
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Reitz, K. M., Varley, P. R., Liang, N. L., Youk, A., George, E. L., Shinall, M. C., ... Hall, D. E.
(2021).
The Correlation Between Case Total Work Relative Value Unit, Operative Stress, and Patient Frailty: Retrospective Cohort Study. ANNALS OF SURGERY.
274(4), 637-645.
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Ghirimoldi, F. M., Schmidt, S., Simon, R. C., Wang, C., Wang, Z., Brimhall, B. B., ... Shireman, P. K.
(2021).
Association of Socioeconomic Area Deprivation Index with Hospital Readmissions After Colon and Rectal Surgery. Journal of Gastrointestinal Surgery.
25(3), 795-808.
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Haney, L. J., Pugh, M., Copeland, L. A., Wang, C., MacCarthy, D. J., Amuan, M. E., & Shireman, P. K.
(2021).
Persistent Pain, Physical Dysfunction, and Decreased Quality of Life After Combat Extremity Vascular Trauma. Annals of Vascular Surgery: international journal of vascular surgery.
71, 167-180.
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George, E. L., Hall, D. E., Youk, A., Chen, R., Kashikar, A., Trickey, A. W., ... Arya, S.
(2021).
Association Between Patient Frailty and Postoperative Mortality Across Multiple Noncardiac Surgical Specialties. JAMA Surgery.
156(1), e205152-e205152.
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Haney, L. J., Bae, E., Pugh, M., Copeland, L. A., Wang, C., MacCarthy, D. J., Amuan, M. E., & Shireman, P. K.
(2020).
Patency of arterial repairs from wartime extremity vascular injuries. Trauma Surgery & Acute Care Open.
5(1), e000616-e000616.
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Pearson, T. A., Califf, R. M., Roper, R., Engelgau, M. M., Khoury, M. J., Alcantara, C., ... Mensah, G. A.
(2020).
Precision Health Analytics With Predictive Analytics and Implementation Research: JACC State-of-the-Art Review. Journal of the American College of Cardiology.
76(3), 306-320.
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Shinall, M. C., Youk, A., Massarweh, N. N., Shireman, P. K., Arya, S., George, E. L., & Hall, D. E.
(2020).
Association of Preoperative Frailty and Operative Stress With Mortality After Elective vs Emergency Surgery. JAMA network open.
3(7), e2010358-e2010358.
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Shinall, M. C., Shireman, P. K., & Hall, D. E.
(2020).
Implications of Preoperative Patient Frailty on Stratified Postoperative Mortality-Reply. JAMA Surgery.
155(7), 670-671.
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Ritter, J. P., Ghirimoldi, F. M., Manuel, L., Moffett, E. E., Novicki, T. J., McClay, J. C., Shireman, P. K., & Brimhall, B. B.
(2020).
Cost of Unnecessary Amylase and Lipase Testing at Multiple Academic Health Systems. American Journal of Clinical Pathology.
153(3), 346-352.
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Shinall, M. C., Arya, S., Youk, A., Varley, P., Shah, R., Massarweh, N. N., ... Hall, D. E.
(2020).
Association of Preoperative Patient Frailty and Operative Stress With Postoperative Mortality. JAMA Surgery.
155(1), e194620-e194620.
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Ramirez, R., Herrera, A. M., Ramirez, J., Qian, C., Melton, D. W., Shireman, P. K., & Jin, Y.
(2019).
Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles. BMC Bioinformatics.
20(1), 725.
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Shireman, P. K., Woo, K., & Lipsitz, E. C.
(2019).
Field testing and refining the hemodialysis access creation episode-based cost measure. Journal of Vascular Surgery.
69(5), 1643-1643.
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Shireman, P. K., Woo, K., & Lipsitz, E. C.
(2019).
Hemodialysis access creation episode-based cost measure. Journal of Vascular Surgery.
69(4), 1322-1322.
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Smith, T. A., Ryan, P., Shireman, P. K., Rathbun, J., & Woo, K.
(2018).
Accessing your Quality Payment Program feedback reports. Journal of Vascular Surgery.
68(6), 1954-1954.
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Woo, K., Rathbun, J., Lipsitz, E. C., & Shireman, P. K.
(2018).
Field testing for the critical limb ischemia cost measure. Journal of Vascular Surgery.
67(6), 1933-1933.
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Schmidt, S., Shay, L. A., Saygin, C., Wan, H., Schulz, K., Clark, R. A., & Shireman, P. K.
(2018).
Improving pilot project application and review processes: A novel application of lean six sigma in translational science. Journal of Clinical and Translational Science.
2(3), 135-138.
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Lipsitz, E. C., Woo, K., Rathbun, J., & Shireman, P. K.
(2018).
Constructing cost measures for critical limb ischemia. Journal of Vascular Surgery.
67(5), 1627-1627.
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Halpern, V. J., Shireman, P. K., Woo, K., Rathbun, J., & Johnson, B.
(2017).
What is an Advanced Alternative Payment Model?. Journal of Vascular Surgery.
66(4), 1299-1299.
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Schmidt, S., Goros, M., Parsons, H. M., Saygin, C., Wan, H., Shireman, P. K., & Gelfond, J.
(2017).
Improving Initiation and Tracking of Research Projects at an Academic Health Center: A Case Study. Evaluation and the Health Professions.
40(3), 372-379.
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Melton, D. W., Roberts, A. C., Wang, H., Sarwar, Z., Wetzel, M. D., Wells, J. T., ... Shireman, P. K.
(2016).
Absence of CCR2 results in an inflammaging environment in young mice with age-independent impairments in muscle regeneration. 100(5), 1011-1025.
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Fearing, C. M., Melton, D. W., Lei, X., Hancock, H., Wang, H., Sarwar, Z. U., ... Shireman, P. K.
(2016).
Increased Adipocyte Area in Injured Muscle With Aging and Impaired Remodeling in Female Mice. Journal of Gerontology Series A: Biological Sciences and Medical Sciences.
71(8), 992-1004.
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Melton, D. W., Lei, X., Gelfond, J., & Shireman, P. K.
(2016).
Dynamic macrophage polarization-specific miRNA patterns reveal increased soluble VEGF receptor 1 by miR-125a-5p inhibition. Physiological Genomics.
48(5), 345-360.
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Melton, D. W., McManus, L. M., Gelfond, J., & Shireman, P. K.
(2015).
Temporal phenotypic features distinguish polarized macrophages in vitro. Autoimmunity.
48(3), 161-176.
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Shireman, P. K., Rasmussen, T. E., Jaramillo, C. A., & Pugh, M. J.
(2015).
VA Vascular Injury Study (VAVIS): VA-DoD extremity injury outcomes collaboration. BMC Surgery.
15(1), 13.
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Wang, H., Melton, D. W., Porter, L., Sarwar, Z. U., McManus, L. M., & Shireman, P. K.
(2014).
Altered macrophage phenotype transition impairs skeletal muscle regeneration. American Journal of Pathology.
184(4), 1167-1184.
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Chen, Y., Melton, D. W., Gelfond, J., McManus, L. M., & Shireman, P. K.
(2012).
MiR-351 transiently increases during muscle regeneration and promotes progenitor cell proliferation and survival upon differentiation. Physiological Genomics.
44(21), 1042-1051.
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McHale, M. J., Sarwar, Z. U., Cardenas, D. P., Porter, L., Salinas, A. S., Michalek, J. E., McManus, L. M., & Shireman, P. K.
(2012).
Increased fat deposition in injured skeletal muscle is regulated by sex-specific hormones. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology.
302(3), R331-R339.
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Chen, Y., Gelfond, J., McManus, L. M., & Shireman, P. K.
(2011).
Temporal microRNA expression during in vitro myogenic progenitor cell proliferation and differentiation: regulation of proliferation by miR-682. Physiological Genomics.
43(10), 621-630.
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Martinez, C. O., McHale, M. J., Wells, J. T., Ochoa, O., Michalek, J. E., McManus, L. M., & Shireman, P. K.
(2010).
Regulation of skeletal muscle regeneration by CCR2-activating chemokines is directly related to macrophage recruitment. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology.
299(3), R832-R842.
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Prajapati, S. I., Martinez, C. O., Abraham, J., McCleish, A. T., Michalek, J. E., McManus, L. M., ... Keller, C.
(2010).
Crimson carrier, a long-acting contrast agent for in vivo near-infrared imaging of injured and diseased muscle. Muscle and Nerve.
42(2), 245-251.
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Martinez, R., Fierro, C. A., Shireman, P. K., & Han, H.
(2010).
Mechanical buckling of veins under internal pressure. Annals of Biomedical Engineering.
38(4), 1345-1353.
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Chen, Y., Gelfond, J., McManus, L. M., & Shireman, P. K.
(2009).
Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis. BMC GENOMICS.
10(1), 407-407.
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Sun, D., Martinez, C. O., Ochoa, O., Ruiz-Willhite, L., Bonilla, J. R., Centonze, V. E., ... Shireman, P. K.
(2009).
Bone marrow-derived cell regulation of skeletal muscle regeneration. The FASEB Journal.
23(2), 382-395.
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Prajapati, S. I., Martinez, C. O., Bahadur, A. N., Wu, I. Q., Zheng, W., Lechleiter, J. D., ... Keller, C.
(2009).
Near-infrared imaging of injured tissue in living subjects using IR-820. Molecular Imaging.
8(1), 45-54.
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Pierce, A. P., de Waal, E., McManus, L. M., Shireman, P. K., & Chaudhuri, A. R.
(2007).
Oxidation and structural perturbation of redox-sensitive enzymes in injured skeletal muscle. Free Radical Biology and Medicine.
43(12), 1584-1593.
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Ochoa, O., Torres, F. M., & Shireman, P. K.
(2007).
Chemokines and diabetic wound healing. 15(6), 350-355.
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Ochoa, O., Sun, D., Reyes-Reyna, S. M., Waite, L. L., Michalek, J. E., McManus, L. M., & Shireman, P. K.
(2007).
Delayed angiogenesis and VEGF production in CCR2-/- mice during impaired skeletal muscle regeneration. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology.
293(2), R651-R661.
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Shireman, P. K.
(2007).
The chemokine system in arteriogenesis and hind limb ischemia. Journal of Vascular Surgery.
45 Suppl A(Suppl A), A48-A56.
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Shireman, P. K., Contreras-Shannon, V., Ochoa, O., Karia, B. P., Michalek, J. E., & McManus, L. M.
(2007).
MCP-1 deficiency causes altered inflammation with impaired skeletal muscle regeneration. 81(3), 775-785.
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Contreras-Shannon, V., Ochoa, O., Reyes-Reyna, S. M., Sun, D., Michalek, J. E., Kuziel, W. A., McManus, L. M., & Shireman, P. K.
(2007).
Fat accumulation with altered inflammation and regeneration in skeletal muscle of CCR2-/- mice following ischemic injury. American Journal of Physiology: Cell Physiology.
292(2), C953-C967.
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Lee, S., Shin, H. S., Shireman, P. K., Vasilaki, A., Van Remmen, H., & Csete, M. E.
(2006).
Glutathione-peroxidase-1 null muscle progenitor cells are globally defective. Free Radical Biology and Medicine.
41(7), 1174-1184.
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Shireman, P. K., Contreras-Shannon, V., Reyes-Reyna, S. M., Robinson, S. C., & McManus, L. M.
(2006).
MCP-1 parallels inflammatory and regenerative responses in ischemic muscle. Journal of Surgical Research.
134(1), 145-157.
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La Fontaine, J., Harkless, L. B., Davis, C. E., Allen, M. A., & Shireman, P. K.
(2006).
Current concepts in diabetic microvascular dysfunction. Journal of the American Podiatric Medical Association.
96(3), 245-252.
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Shireman, P. K., & Quinones, M. P.
(2005).
Differential necrosis despite similar perfusion in mouse strains after ischemia. Journal of Surgical Research.
129(2), 242-250.
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Toursarkissian, B., Hagino, R. T., Khan, K., Schoolfield, J., Shireman, P. K., & Harkless, L.
(2005).
Healing of transmetatarsal amputation in the diabetic patient: is angiography predictive?. Annals of Vascular Surgery: international journal of vascular surgery.
19(6), 769-773.
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Jones, W. T., Toursarkissian, B., Dayala, M., Shireman, P. K., & Schoolfield, J.
(2003).
Duplex screening for asymptomatic carotid artery disease in Hispanic diabetic patients undergoing lower extremity revascularization: is it a worthwhile endeavor?. Texas Medicine.
99(12), 50-53.
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Toursarkissian, B., Shireman, P. K., Schoolfield, J., & Blumoff, R. L.
(2003).
Outcomes following distal bypass graft occlusion in diabetics. Annals of Vascular Surgery: international journal of vascular surgery.
17(6), 670-675.
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Toursarkissian, B., Stefanidis, D., Hagino, R. T., D'Ayala, M., Schoolfield, J., Shireman, P. K., & Sykes, M. T.
(2002).
Early duplex-derived hemodynamic parameters after lower extremity bypass in diabetics: implications for mid-term outcomes. Annals of Vascular Surgery: international journal of vascular surgery.
16(5), 601-607.
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Toursarkissian, B., Shireman, P. K., Harrison, A., D'Ayala, M., Schoolfield, J., & Sykes, M. T.
(2002).
Major lower-extremity amputation: contemporary experience in a single Veterans Affairs institution. American Surgeon.
68(7), 606-610.
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Toursarkissian, B., Connaughton, J. C., D'Ayala, M., Shireman, P. K., Harrison, A., Schoolfield, J., & Sykes, M. T.
(2002).
Does lower limb revascularization result in an improvement in sensory perception thresholds?. Annals of Vascular Surgery: international journal of vascular surgery.
16(3), 309-313.
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Toursarkissian, B., Jones, W. T., D'Ayala, M. D., Shireman, P. K., Harrison, A., Schoolfield, J., & Sykes, M. T.
(2002).
Does the efficacy of dorsalis pedis artery bypasses vary among diabetic patients of different ethnic backgrounds?. Vascular and Endovascular Surgery.
36(3), 207-212.
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Toursarkissian, B., D'Ayala, M., Stefanidis, D., Shireman, P. K., Harrison, A., Schoolfield, J., & Sykes, M. T.
(2002).
Angiographic scoring of vascular occlusive disease in the diabetic foot: relevance to bypass graft patency and limb salvage. Journal of Vascular Surgery.
35(3), 494-500.
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Toursarkissian, B., D'Ayala, M., Shireman, P. K., Schoolfield, J., & Sykes, M. T.
(2001).
Lower extremity bypass graft revision in diabetics. Vascular surgery.
35(5), 369-377.
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Sheehan, M. K., Shireman, P. K., Littooy, F. N., & Baker, W. H.
(2001).
Ureteral injury during aortic aneurysm repair by the retroperitoneal approach. Annals of Vascular Surgery: international journal of vascular surgery.
15(4), 481-484.
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Toursarkissian, B., Mejia, A., Smilanich, R. P., Shireman, P. K., & Sykes, M. T.
(2001).
Changing patterns of access site complications with the use of percutaneous closure devices. Vascular surgery.
35(3), 203-206.
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Toursarkissian, B., Mejia, A., Smilanich, R. P., Schoolfield, J., Shireman, P. K., & Sykes, M. T.
(2001).
Noninvasive localization of infrainguinal arterial occlusive disease in diabetics. Annals of Vascular Surgery: international journal of vascular surgery.
15(1), 73-78.
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Xue, L., Shireman, P. K., Hampton, B., Burgess, W. H., & Greisler, H. P.
(2000).
The cysteine-free fibroblast growth factor 1 mutant induces heparin-independent proliferation of endothelial cells and smooth muscle cells. Journal of Surgical Research.
92(2), 255-260.
-
Shireman, P. K., & Greisler, H. P.
(2000).
Mitogenicity and release of vascular endothelial growth factor with and without heparin from fibrin glue. Journal of Vascular Surgery.
31(5), 936-943.
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Shireman, P. K., Xue, L., Maddox, E., Burgess, W. H., & Greisler, H. P.
(2000).
The S130K fibroblast growth factor-1 mutant induces heparin-independent proliferation and is resistant to thrombin degradation in fibrin glue. Journal of Vascular Surgery.
31(2), 382-390.
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Shireman, P. K., Hampton, B., Burgess, W. H., & Greisler, H. P.
(1999).
Modulation of vascular cell growth kinetics by local cytokine delivery from fibrin glue suspensions. Journal of Vascular Surgery.
29(5), 852-861.
-
Shireman, P. K., & Greisler, H. P.
(1998).
Fibrin sealant in vascular surgery: a review. Journal of Long-Term Effects of Medical Implants.
8(2), 117-132.
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Shireman, P. K., McCarthy, W. J., Yao, J. S., & Vogelzang, R. L.
(1997).
Treatment of venous malformations by direct injection with ethanol. Journal of Vascular Surgery.
26(5), 838-844.
-
Shireman, P. K., McCarthy, W. J., Pearce, W. H., Shively, V. P., Cipollone, M., & Kwaan, H. C.
(1997).
Elevations of tissue-type plasminogen activator and differential expression of urokinase-type plasminogen activator in diseased aorta. Journal of Vascular Surgery.
25(1), 157-164.
-
Shireman, P. K., McCarthy, W. J., Pearce, W. H., Shively, V. P., Cipollone, M., Kwaan, H. C., & Yao, J. S.
(1996).
Plasminogen activator levels are influenced by location and varicosity in greater saphenous vein. Journal of Vascular Surgery.
24(5), 719-724.
-
Shireman, P. K., McCarthy, W. J., Pearce, W. H., Patterson, B. K., Shively, V. P., Cipollone, M., ... Kwaan, H. C.
(1996).
Elevated levels of plasminogen-activator inhibitor type 1 in atherosclerotic aorta. Journal of Vascular Surgery.
23(5), 810-817.
-
Shireman, P. K., & Pearce, W. H.
(1996).
Endothelial cell function: biologic and physiologic functions in health and disease. American Journal of Roentgenology.
166(1), 7-13.
-
Keen, R. R., McCarthy, W. J., Shireman, P. K., Feinglass, J., Pearce, W. H., Durham, J. R., & Yao, J. S.
(1995).
Surgical management of atheroembolization. Journal of Vascular Surgery.
21(5), 773-780.
-
Mesh, C. L., McCarthy, W. J., Pearce, W. H., Flinn, W. R., Shireman, P. K., & Yao, J. S.
(1993).
Upper extremity bypass grafting. A 15-year experience. Archives of Surgery.
128(7), 795-801.
-
Duncan, C. A., Jacobs, M. A., Gao, Y., Mader, M., Schmidt, S., Davila, H., ... Hall, D. E.
Care Fragmentation, Social Determinants of Health, and Postoperative Mortality in Older Veterans. Journal of Surgical Research.
300, 514-525.
-
Hadlandsmyth, K., Lund, B. C., Gao, Y., Strayer, A. L., Davila, H., Hausmann, L., ... Sarrazin, M. V.
Social Determinants of Long-Term Opioid Use Following Total Knee Arthroplasty. Journal of Knee Surgery.
37(10), 742-748.
-
Schmidt, S., Jacobs, M. A., Kim, J., Hall, D. E., Stitzenberg, K. B., Kao, L. S., ... Shireman, P. K.
(2024).
Presentation Acuity and Surgical Outcomes for Patients With Health Insurance Living in Highly Deprived Neighborhoods. JAMA Surgery.
159(4), 411-419.
-
chapter
-
Shireman, P. K., & Martinez, C. O.
(2010).
CHAPTER 7 Arteriogenesis. Rutherford's Vascular Surgery.
(pp. 101-115).
Elsevier.
-
Shireman, P. K.
(2009).
Chapter 69. Deep Venous Thrombosis. Cohn, S. M. (Eds.),
Acute Care Surgery and Trauma Evidence-Based Practice.
(pp. 433-437).
Informa Healthcare, Inc.
-
Shireman, P. K., & Greisler, H. P.
(1999).
Angiogenesis in tissues and vascular grafts. Zilla, P., & Greisler, H. P. (Eds.),
Tissue Engineering of Prosthetic Vascular Grafts.
(pp. 279-286).
R G Landes Co.
-
Blumofe, K. A., Heilizer, T. J., Shireman, P. K., & Greisler, H. P.
(1999).
Fibroblast growth factors in angiogenesis and tissue engineering. Zilla, P., & Greisler, H. P. (Eds.),
Tissue Engineering of Prosthetic Vascular Grafts.
(pp. 301-312).
Landes Bioscience.
-
McCarthy, W. J., & Shireman, P. K.
(1995).
Composite prosthetic-vein grafts. Whittemore, A. D., & Bandyk, D. F. (Eds.),
Advances in Vascular Surgery.
(pp. 121-132).
Mosby Incorporated.
-
Shireman, P. K., & Martinez, C. O.
(2010).
CHAPTER 7 Arteriogenesis. Rutherford's Vascular Surgery.
(pp. 101-115).
Elsevier.
-
conference paper
-
Li, S. R., Reitz, K. M., Gabriel, L., Phillips, A. R., Shireman, P. K., Eslami, M., & Edith, T.
(2021).
Abstract 10519: The Epidemiology of Race- and Sex-Specific Hospitalizations for Abdominal Aortic Aneurysms. Circulation.
a10519-a10519.
-
Kim, J., Simon, R. C., Schmidt, S., Brimhall, B. B., Wang, C., Wang, Z., ... Shireman, P. K.
(2021).
Association of High Area Deprivation Index and Textbook Outcomes after Inpatient Surgical Procedures. Journal of the American College of Surgeons.
s117-S117.
-
Simon, R. C., Kim, J., Schmidt, S., Brimhall, B. B., Wang, C., Wang, Z., ... Shireman, P. K.
(2021).
Association of Insurance Status with Inpatient Surgery 30-day Outcomes At a Safety-net Hospital. Journal of the American College of Surgeons.
s117-s118.
-
Yan, Q. i., Kim, J., Reitz, K. M., Hall, D. E., Shinall, M. C., Stitzenberg, K. B., ... Shireman, P. K.
(2021).
Sex Differences in Postoperative Complications and Mortality. Journal of the American College of Surgeons.
s122-s123.
-
Sorber, R., Canner, J. K., Abularrage, C. J., Shireman, P. K., Segev, D. L., Black, J. H., Woo, K., & Hicks, C. W.
(2021).
Quantifying The Charges Of Creating And Maintaining Hemodialysis Access In An All-payer Rate-controlled Health System. Annals of Vascular Surgery: international journal of vascular surgery.
454-454.
-
Yan, Q. i., Hall, D. E., Shinall, M. C., Stitzenberg, K. B., Kao, L. S., George, E., ... Shireman, P. K.
(2020).
Association of Patient Frailty and Operative Stress with Postoperative Mortality: No Such Thing as Low-Risk Operations in Frail Adults. Journal of the American College of Surgeons.
s134-s135.
-
Reitz, K. M., Varley, P., Youk, A. O., Shinall, M. C., George, E., Tzeng, E., Shireman, P. K., & Hall, D. E.
(2020).
Relationship Between Operative Stress, Patient Frailty, and Financial Reimbursement. Journal of the American College of Surgeons.
s118-S118.
-
Haney, L. J., Bae, E., Pugh, M., Copeland, L. A., Wang, C., MacCarthy, D. J., Amuan, M. E., & Shireman, P. K.
(2020).
Characteristics and Distribution of Extremity Vascular Injuries in a Wartime Military Cohort. Journal of Vascular Surgery.
e165-e166.
-
Bae, E., Haney, L. J., Pugh, M., Copeland, L. A., Wang, C., MacCarthy, D. J., Amuan, M. E., & Shireman, P. K.
(2020).
Durable Long-term Patency of Arterial Repairs From Wartime Extremity Vascular Injuries. Journal of Vascular Surgery.
e164-e165.
-
Ritter, J., Ghirimoldi, F., Manuel, L., Moffett, E., Shireman, P., & Brimhall, B.
(2019).
Choosing Wisely: Persistent Amylase Concurrent With Lipase Testing at Multiple Academic Health Systems. American Journal of Clinical Pathology.
s125-s125.
-
Fearing, C. M., Hancock, H. M., McHale, M. J., Porter, L., Sarwar, Z. U., McManus, L. M., & Shireman, P. K.
(2013).
Increased Adipocyte Deposition in Injured Muscle With Aging and Impaired Remodeling in Females. Journal of Surgical Research.
200-200.
-
Hancock, H. M., McHale, M., Porter, L., Sarwar, Z., McManus, L. M., & Shireman, P. K.
(2012).
PS214. Aging Does Not Affect Muscle Regenerative Capacity in Mice. Journal of Vascular Surgery.
81s-81S.
-
WANG, H., Porter, L., Sarwar, Z., McManus, L. M., & Shireman, P. K.
(2012).
Proinflammatory macrophage ablation in CD11bdiphtheria toxin receptor (DTR) transgenic mice impairs skeletal muscle regeneration. The FASEB Journal.
136.5-136.5.
-
Melton, D. W., Gelfond, J., Chen, Y., McManus, L., & Shireman, P.
(2012).
Unique microRNA expression patterns associated with macrophage infiltration following skeletal muscle injury. The FASEB Journal.
1034.18-1034.18.
-
Wang, H., Porter, L., Sarwar, Z. U., Wells, J. T., McManus, L. M., & Shireman, P. K.
(2011).
Macrophage Ablation in CD11bdiphtheria Toxin Receptor (DTR) Transgenic Mice Impairs Skeletal Muscle Regeneration. The FASEB Journal.
614.17-614.17.
-
Hancock, H. M., McHale, M., Porter, L., Sarwar, Z., McManus, L. M., & Shireman, P. K.
(2011).
Despite sarcopenia, aging does not affect myofiber regenerative capacity in mice. Pathobiology of Aging & Age-related Diseases.
15-15.
-
Melton, D. W., Gelfond, J., Chen, Y., McManus, L. M., & Shireman, P. K.
(2011).
Differential microRNA expression patterns in CCR2-/- versus wild type mice following skeletal muscle injury. Pathobiology of Aging & Age-related Diseases.
14729-14729.
-
Chen, Y., Gelfond, J., McManus, L. M., & Shireman, P. K.
(2010).
MiRNA Expression Patterns during Skeletal Muscle Regeneration. The FASEB Journal.
568.5-568.5.
-
McHale, M. J., Schlechter, A. K., Torres, F. M., Michalek, J. E., McManus, L. M., & Shireman, P. K.
(2010).
Gender-Specific Differences in Skeletal Muscle Regeneration. Journal of Surgical Research.
218-218.
-
Martinez, C. O., McManus, L. M., & Shireman, P. K.
(2009).
Kinetics of myogenic progenitor cell (MPC) expansion and bone marrowderived cell recruitment in skeletal muscle regeneration. The FASEB Journal.
739.1-739.1.
-
Chen, Y., Gelfond, J., McManus, L. M., & Shireman, P. K.
(2009).
Reproducibility of miRNA Expression by Proliferating C2C12 Cells Using RTPCR Array. The FASEB Journal.
361.4-361.4.
-
Sun, D., Wetzel, M. D., Waite, L. L., Michalek, J. E., McManus, L. M., & Shireman, P. K.
(2008).
92. Environmental Factors Determine In Vivo Myogenic Progenitor Cell Function. Journal of Surgical Research.
217-218.
-
Ochoa, O., Martinez, C. O., Torres, F. M., Ruiz-Willhite, L., Michalek, J. E., McManus, L. M., & Shireman, P. K.
(2008).
93. Differential Regulation of Skeletal Muscle Regeneration and Angiogenesis by CCR2 Activating Chemokines. Journal of Surgical Research.
218-219.
-
Sun, D., Wetzel, M. D., Waite, L. L., Michalek, J. E., McManus, L. M., & Shireman, P. K.
(2008).
P8. Environmental Factors Determine in Vivo Myogenic Progenitor Cell Function. Journal of Surgical Research.
447-447.
-
Ochoa, O., Solomon, D., Michalek, J., McManus, L. M., & Shireman, P. K.
(2007).
141 Similar capillary density despite decreased vascular endothelial growth factor (VEGF) levels and impaired skeletal muscle regeneration in CC chemokine receptor 2 (CCR2) / mice. Journal of Surgical Research.
211-212.
-
Sun, D., Ochoa, O., McManus, L. M., & Shireman, P. K.
(2007).
71 Bone marrow (BM) transplantation corrects impaired macrophage recruitment and muscle regeneration in CC chemokine receptor 2 (CCR2) -/- mice. Journal of Surgical Research.
180-181.
-
Ochoa, O., Shireman, P. K., & McManus, L. M.
(2006).
Altered inflammation increases intramuscular fat accumulation and impairs skeletal muscle regeneration following ischemic injury in CCR2/ mice. Journal of the American College of Surgeons.
s101-S101.
-
Contreras-Shannon, V., McManus, L. M., & Shireman, P. K.
(2006).
Ischemia-induced enhanced transcription factor (Myod and STAT3) expression in MCP-1 / mice despite descreased skeletal muscle regeneration. Journal of Surgical Research.
183-184.
-
Toursarkissian, B., Mejia, A., Smilanich, R. P., Schoolfield, J., Shireman, P. K., & Sykes, M. T.
(2001).
Noninvasive localization of infrainguinal arterial occlusive disease in diabetics. Annals of Vascular Surgery: international journal of vascular surgery.
73-78.
-
Shireman, P. K., & Greisler, H. P.
(1999).
Mitogenicity of VEGF Heparin in Fibrin Glue (FG). Journal of Vascular and Interventional Radiology.
988-989.
-
Chen, Y., Gelfond, J. A., McManus, L. M., & Shireman, P. K.
MiR682 Antisense Inhibits Skeletal Muscle Regeneration. The FASEB Journal.
441.12-441.12.
-
Wells, J. T., McManus, L. M., & Shireman, P. K.
Skeletal Muscle Regeneration is Dependent upon CCR2 Expression on Bone Marrow (BM)Derived Cells. The FASEB Journal.
614.2-614.2.
-
Li, S. R., Reitz, K. M., Gabriel, L., Phillips, A. R., Shireman, P. K., Eslami, M., & Edith, T.
(2021).
Abstract 10519: The Epidemiology of Race- and Sex-Specific Hospitalizations for Abdominal Aortic Aneurysms. Circulation.
a10519-a10519.
Research
principal investigator on
- HX003095/IIR 19-414 Understanding the effect of rurality and social risk factors on barriers to care and surgical outcomes awarded by Veterans Health Administration - (Washington D.C., District of Columbia, United States) 2021 - 2025
- U01TR002393 Harnessing the power of CTSA-CDRN data networks: Using social determinants of health, frailty and functional status to identify at-risk patients & improve risk adjustment awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2018 - 2024
- HX001304/IIR 13-029 VA Vascular Injury Study (VAVIS): VA-DOD extremity injury outcomes collaboration awarded by Veterans Health Administration - (Washington D.C., District of Columbia, United States) 2015 - 2020
- BX001186 MicroRNA regulation of macrophage polarization in muscle regeneration awarded by Veterans Health Administration - (Washington D.C., District of Columbia, United States) 2011 - 2015
- Macrophage regulated muscle regeneration: fat deposition and function awarded by Veterans Health Administration - (Washington D.C., District of Columbia, United States) 2007 - 2011
- R01 HL074236 Chemokines and Immune Cells in Hind Limb Ischemia awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2003 - 2011
- Role of the MCP-1/CCR2 axis in hind limb ischemia awarded by Veterans Health Administration - (Washington D.C., District of Columbia, United States) 2004 - 2007
- KO8 HL70158 The chemokine system in collateral artery formation awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2002 - 2007
co-principal investigator on
- P30AG044271 San Antonio Claude D. Pepper Older Americans Independence Center awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2015 - 2025
- UL1TR002645 Institute for Integration of Medicine & Science: A Partnership to Improve Health (CTSA) awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2018 - 2023
- UL1 TR001120 Institute for Integration of Medicine and Science: A Partnership to Improve Health awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2013 - 2018
investigator on
Teaching
teaching activities
- MSCI689 Sptp: Intro To Clinical Pract Instructor
Background
education and training
- B.C. in Clinical Informatics, American Board of Preventive Medicine - (Chicago, Illinois, United States) 2020
- B.C. in Certified Wound Specialist Physician, American Board of Wound Management - (Washington D.C., ) 2020
- M.B.A. in Business Administration, The University of Texas at Austin - (Austin, Texas, United States) 2018
- M.S. in Clinical Investigation, The University of Texas Health Science Center at San Antonio - (San Antonio, Texas, United States) 2004
- B.C. in Vascular Surgery, The American Board of Surgery - (Philadelphia, Pennsylvania, United States) 2000
- B.C. in General Surgery, The American Board of Surgery - (Philadelphia, Pennsylvania, United States) 2000
- M.D., Indiana University School of Medicine - Indianapolis - (Indianapolis, Indiana, United States) 1990
- B.S. in Nutrition Science, Purdue University - (West Lafayette, Indiana, United States) 1986
- Loyola University Medical Center - (Maywood, Illinois, United States) , Medical Residency 1999
- Northwestern Memorial Hospital - (Chicago, Illinois, United States) , Medical Residency 1997
- Northwestern Medicine - (Chicago, Illinois, United States) , Postdoctoral Training 1995
awards and honors
- Nutrition Science Hall of Fame, conferred by Purdue University - (West Lafayette, Indiana, United States), 2014
- Dielmann Chair in Surgery, conferred by The University of Texas Health Science Center at San Antonio - (San Antonio, Texas, United States), 2011
- Distinguished Fellow, conferred by Society for Vascular Surgery - (Chicago, Illinois, United States), 2010
- Outstanding Alumni, conferred by Purdue University - (West Lafayette, Indiana, United States), 2004
- Presidential Junior Research Scholar Award, conferred by The University of Texas Health Science Center at San Antonio - (San Antonio, Texas, United States), 2004
- Alumni Hidden Diamond, conferred by Purdue University - (West Lafayette, Indiana, United States), 2001
- John L Keeley Surgical Fellowship, conferred by Loyola University Medical Center - (Maywood, Illinois, United States), 1999
Contact
first name
- Paula
has last name
- Shireman
mailing address
-
8447 Riverside Parkway
Bryan, Texas 77807
USA
Other
- shireman@tamu.edu