HR job title
- Professor
- Contact Info
- 1 979 458 0763
Nikolov, Zivko Professor and Associate Department Head
Positions
- Professor and Associate Department Head, Biological and Agricultural Engineering, College of Agriculture and Life Sciences
- Faculty Affiliate, Energy Institute, Texas A&M Engineering Experiment Station (TEES)
Nikolov's Bioseparations Lab conducts transformative research in bioprocess engineering aimed at the development of novel and cost-effective strategies for extraction and purification of recombinant and native biomolecules. Bioseparations Lab leverages scientific and engineering expertise of lab members to find solutions for a variety of bioprocessing and separations challenges that currently face plant and algal biotechnology. To guide early process development and identify constraints posed by biological system and final product lab members use process simulation. Past and current research projects directed by Dr. Nikolov include industrial protein products derived from rice, sugarcane, tobacco, Lemna minor, and microalgae.
- Overview
- Publications
- Research
- Teaching
- Works By Students
- Background
- Contact
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Overview
Publications
selected publications
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academic article
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Soto-Sierra, L., Wilken, L. R., Mallawarachchi, S., & Nikolov, Z. L.
(2021).
Process development of enzymatically-generated algal protein hydrolysates for specialty food applications. Algal Research.
55, 102248-102248.
-
Goike, J., Hsieh, C., Horton, A., Gardner, E. C., Bartzoka, F., Wang, N., ... Gollihar, J. D.
(2021).
Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality. 2(04-13), 2021.04.07.438849.
-
Soto-Sierra, L., Kulkarni, S., Woodard, S. L., & Nikolov, Z. L.
(2020).
Processing of permeabilized Chlorella vulgaris biomass into lutein and protein-rich products. JOURNAL OF APPLIED PHYCOLOGY.
32(3), 1697-1707.
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Ravi, A., Foster, E. R., Perez, L. M., & Nikolov, Z. L.
(2020).
Capture chromatography with mixed-mode resins: A case study with recombinant human thioredoxin from Escherichia coli. Journal of Chromatography A.
1625, 461327-461327.
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Damaj, M. B., Jifon, J. L., Woodard, S. L., Vargas-Bautista, C., Barros, G., Molina, J., ... Mandadi, K. K.
(2020).
Unprecedented enhancement of recombinant protein production in sugarcane culms using a combinatorial promoter stacking system. Scientific Reports.
10(1), 13713.
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Guo, S., Ravi, A., Mayfield, S., & L Nikolov, Z.
(2019).
Exploring the separation power of mixed-modal resins for purification of recombinant osteopontin from clarified Escherichia coli lysates. Biotechnology Progress.
35(1), e2722.
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Marrone, B. L., Lacey, R. E., Anderson, D. B., Bonner, J., Coons, J., Dale, T., ... Olivares, J. A.
(2018).
Review of the harvesting and extraction program within the National Alliance for Advanced Biofuels and Bioproducts. Algal Research.
33, 470-485.
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Ravi, A., Guo, S., Rasala, B., Tran, M., Mayfield, S., & Nikolov, Z. L.
(2018).
Separation Options for Phosphorylated Osteopontin from Transgenic Microalgae Chlamydomonas reinhardtii. International Journal of Molecular Sciences.
19(2), 585-585.
-
Soto-Sierra, L., Stoykova, P., & Nikolov, Z. L.
(2018).
Extraction and fractionation of microalgae-based protein products. Algal Research.
36, 175-192.
-
Kulkarni, S., & Nikolov, Z.
(2018).
Process for selective extraction of pigments and functional proteins from Chlorella vulgaris. Algal Research.
35, 185-193.
-
Wilken, L. R., Ogle, E. T., Lohrmann, T., & Nikolov, Z. L.
(2016).
Impact of Dry-milled Germ Processing on Aqueous Protein and Oil Extraction. Food and Bioprocess Technology.
9(4), 612-620.
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Munjal, N., Kulkarni, S., Quinones, K., Tran, M., Mayfield, S. P., & Nikolov, Z. L.
(2015).
Evaluation of pretreatment methods for primary recovery and capture of an antibody fragment (alpha CD22scFv) from Chlamydomonas reinhardtii lysates. Algal Research.
12, 455-462.
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Munjal, N., Juliana Garzon-Sanabria, A., Quinones, K. W., Gregory, J., & Nikolov, Z. L.
(2014).
Light-Induced Production of An Antibody Fragment and Malaria Vaccine Antigen from Chlamydomonas reinhardtii. 2(3), 625-638.
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Hood, N. C., Hood, K. R., Woodard, S. L., Devaiah, S. P., Jeoh, T., Wilken, L., ... Hood, E. E.
(2014).
Purification and characterization of recombinant Cel7A from maize seed. Applied Biochemistry and Biotechnology.
174(8), 2864-2874.
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Egelkrout, E., McGaughey, K., Keener, T., Ferleman, A., Woodard, S., Devaiah, S., ... Howard, J.
(2013).
Enhanced Expression Levels of Cellulase Enzymes Using Multiple Transcription Units. 6(2), 699-710.
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Garzon-Sanabria, A. J., Ramirez-Caballero, S. S., Moss, F., & Nikolov, Z. L.
(2013).
Effect of algogenic organic matter (AOM) and sodium chloride on Nannochloropsis salina flocculation efficiency. 143, 231-237.
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Barros, G., Ballen, M., Woodard, S. L., Wilken, L. R., White, S. G., Damaj, M. B., Mirkov, T. E., & Nikolov, Z. L.
(2013).
Recovery of bovine lysozyme from transgenic sugarcane stalks: extraction, membrane filtration, and purification. Bioprocess Biosyst Eng.
36(10), 1407-1416.
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Wilken, L. R., & Nikolov, Z. L.
(2012).
Recovery and purification of plant-made recombinant proteins. 30(2), 419-433.
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Garzon-Sanabria, A. J., Davis, R. T., & Nikolov, Z. L.
(2012).
Harvesting Nannochloris oculata by inorganic electrolyte flocculation: effect of initial cell density, ionic strength, coagulant dosage, and media pH. 118, 418-424.
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Wilken, L. R., & Nikolov, Z. L.
(2011).
Process evaluations and economic analyses of recombinant human lysozyme and hen egg‐white lysozyme purifications. Biotechnology Progress.
27(3), 733-743.
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Barros, G., Woodard, S. L., & Nikolov, Z. L.
(2011).
Phenolics removal from transgenic Lemna minor extracts expressing mAb and impact on mAb production cost. 27(2), 410-418.
-
Wilken, L. R., & Nikolov, Z. L.
(2010).
Evaluation of alternatives for human lysozyme purification from transgenic rice: impact of phytic acid and buffer. 26(5), 1303-1311.
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Woodard, S. L., Wilken, L. R., Barros, G., White, S. G., & Nikolov, Z. L.
(2009).
Evaluation of monoclonal antibody and phenolic extraction from transgenic Lemna for purification process development. Biotechnology and Bioengineering.
104(3), 562-571.
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Wilken, L. R., & Nikolov, Z. L.
(2006).
Factors influencing recombinant human lysozyme extraction and cation exchange adsorption. Biotechnology Progress.
22(3), 745-752.
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Zhu, L., van de Lavoir, M., Albanese, J., Beenhouwer, D. O., Cardarelli, P. M., Cuison, S., ... Etches, R. J.
(2005).
Production of human monoclonal antibody in eggs of chimeric chickens. Nature Biotechnology.
23(9), 1159-1169.
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Azzoni, A. R., Takahashi, K., Woodard, S. L., Miranda, E. A., & Nikolov, Z. L.
(2005).
Purification of recombinant aprotinin produced in transgenic corn seed: Separation from CTI utilizing ion-exchange chromatography. 22(3), 323-330.
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Menkhaus, T. J., Bai, Y., Zhang, C., Nikolov, Z. L., & Glatz, C. E.
(2004).
Considerations for the recovery of recombinant proteins from plants. Biotechnology Progress.
20(4), 1001-1014.
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Nikolov, Z. L., & Woodard, S. L.
(2004).
Downstream processing of recombinant proteins from transgenic feedstock. Current Opinion in Biotechnology.
15(5), 479-486.
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Azzoni, A. R., Kusnadi, A. R., Miranda, E. A., & Nikolov, Z. L.
(2002).
Recombinant aprotinin produced in transgenic corn seed: Extraction and purification studies. Biotechnology and Bioengineering.
80(3), 268-276.
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Hood, E. E., & Nikolov, Z. L.
(2002).
Making therapeutic proteins in transgenic corn. GENETIC ENGINEERING NEWS.
22(16), 48-48.
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Bai, Y., Nikolov, Z. L., & Glatz, C. E.
(2002).
Aqueous extraction of beta-glucuronidase from transgenic canola: kinetics and microstructure. Biotechnology Progress.
18(6), 1301-1305.
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Yildirim, S., Fuentes, R. G., Evangelista, R., & Nikolov, Z. L.
(2002).
Fractionation of transgenic corn for recovery of recombinant enzymes. JAOCS.
79(8), 809-814.
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Bai, Y., & Nikolov, Z. L.
(2001).
Effect of processing on the recovery of recombinant beta-glucuronidase (rGUS) from transgenic canola. Biotechnology Progress.
17(1), 168-174.
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Ferreira, S., Nikolov, Z. L., Doraiswamy, L. K., Meireles, M., & Petenate, A. J.
(1999).
Supercritical fluid extraction of black pepper (Piper nigrun L.) essential oil. 14(3), 235-245.
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Kusnadi, A. R., Evangelista, R. L., Hood, E. E., Howard, J. A., & Nikolov, Z. L.
(1998).
Processing of transgenic corn seed and its effect on the recovery of recombinant beta-glucuronidase. 60(1), 44-52.
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Chang, H. Y., Irwin, P. M., & Nikolov, Z. L.
(1998).
Effects of mutations in the starch-binding domain of Bacillus macerans cyclodextrin glycosyltransferase. Journal of Biotechnology.
65(2-3), 191-202.
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Evangelista, R. L., Kusnadi, A. R., Howard, J. A., & Nikolov, Z. L.
(1998).
Process and economic evaluation of the extraction and purification of recombinant beta-glucuronidase from transgenic corn. Biotechnology Progress.
14(4), 607-614.
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Kusnadi, A. R., Evangelista, R. L., Hood, E. E., Howard, J. A., & Nikolov, Z. L.
(1998).
Processing of transgenic corn seed and its effect on the recovery of recombinant -glucuronidase. Biotechnology and Bioengineering.
60(1), 44-52.
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Kusnadi, A. R., Hood, E. E., Witcher, D. R., Howard, J. A., & Nikolov, Z. L.
(1998).
Production and purification of two recombinant proteins from transgenic corn. Biotechnology Progress.
14(1), 149-155.
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Kusnadi, A. R., Nikolov, Z. L., & Howard, J. A.
(1997).
Production of recombinant proteins in transgenic plants: Practical considerations. 56(5), 473-484.
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Maheshwari, P., Murphy, P. A., & Nikolov, Z. L.
(1997).
Characterization and application of porcine liver aldehyde oxidase in the off-flavor reduction of soy proteins. Journal of Agricultural and Food Chemistry.
45(7), 2488-2494.
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Kusnadi, A. R., Nikolov, Z. L., & Howard, J. A.
(1997).
Production of recombinant proteins in transgenic plants: Practical considerations. Biotechnology and Bioengineering.
56(5), 473-484.
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Evangelista, R. L., & Nikolov, Z. L.
(1996).
Recovery and purification of lactic acid from fermentation broth by adsorption. 57-8(1), 471-480.
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MAHESHWARI, P., OOI, E. T., & NIKOLOV, Z. L.
(1995).
OFF-FLAVOR REMOVAL FROM SOY-PROTEIN ISOLATE BY USING LIQUID AND SUPERCRITICAL CARBON-DIOXIDE. 72(10), 1107-1115.
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Dalmia, B. K., Schtte, K., & Nikolov, Z. L.
(1995).
Domain E of Bacillus macerans cyclodextrin glucanotransferase: An independent starch-binding domain. Biotechnology and Bioengineering.
47(5), 575-584.
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CANTARELLA, L., NIKOLOV, Z. L., & REILLY, P. J.
(1994).
DISACCHARIDE PRODUCTION BY GLUCOAMYLASE IN AQUEOUS ETHER MIXTURES. 16(5), 383-387.
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EVANGELISTA, R. L., MANGOLD, A. J., & NIKOLOV, Z. L.
(1994).
RECOVERY OF LACTIC-ACID BY SORPTION - RESIN EVALUATION. 45-6(1), 131-144.
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Dalmia, B. K., & Nikolov, Z. L.
(1994).
A glutathione S-transferase fusion protein with the starch-binding domain of Aspergillus glucoamylase. Annals of the New York Academy of Sciences.
721(1), 160-167.
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Kusnadi, A. R., Chang, H. Y., Nikolov, Z. L., Metzler, D. E., & Metzler, C. M.
(1994).
Starch-binding domain of Aspergillus glucoamylase-I. Interaction with beta-cyclodextrin and maltoheptaose. Annals of the New York Academy of Sciences.
721(1), 168-177.
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DALMIA, B. K., & NIKOLOV, Z. L.
(1994).
CHARACTERIZATION OF A BETA-GALACTOSIDASE FUSION PROTEIN CONTAINING THE STARCH-BINDING DOMAIN OF ASPERGILLUS GLUCOAMYLASE. 16(1), 18-23.
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Johnson, K. E., Pometto, A. L., & Nikolov, Z. L.
(1993).
Degradation of Degradable Starch-Polyethylene Plastics in a Compost Environment. Applied and Environmental Microbiology.
59(4), 1155-1161.
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Kusnadi, A. R., Ford, C., & Nikolov, Z. L.
(1993).
Functional starch-binding domain of Aspergillus glucoamylase I in Escherichia coli. Gene.
127(2), 193-197.
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MAHESHWARI, P., NIKOLOV, Z. L., WHITE, T. M., & HARTEL, R.
(1992).
SOLUBILITY OF FATTY-ACIDS IN SUPERCRITICAL CARBON-DIOXIDE. 69(11), 1069-1076.
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SUNG, W., & NIKOLOV, Z. L.
(1992).
ACCELERATED DEGRADATION STUDIES OF STARCH-FILLED POLYETHYLENE FILMS. Industrial & Engineering Chemistry Research.
31(10), 2332-2339.
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DALMIA, B. K., & NIKOLOV, Z. L.
(1991).
CHARACTERIZATION OF GLUCOAMYLASE ADSORPTION TO RAW STARCH. 13(12), 982-990.
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Chen, L. J., Ford, C., Kusnadi, A., & Nikolov, Z. L.
(1991).
Improved adsorption to starch of a beta-galactosidase fusion protein containing the starch-binding domain from Aspergillus glucoamylase. Biotechnology Progress.
7(3), 225-229.
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FRATZKE, A. R., SUNG, W., EVANGELISTA, R. L., & NIKOLOV, Z. L.
(1991).
CHEMICAL METHOD FOR THE DETERMINATION OF STARCH IN POLYETHYLENE. ANALYTICAL LETTERS.
24(5), 847-856.
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EVANGELISTA, R. L., NIKOLOV, Z. L., WEI, S., JANE, J. L., & GELINA, R. J.
(1991).
EFFECT OF COMPOUNDING AND STARCH MODIFICATION ON PROPERTIES OF STARCH-FILLED LOW-DENSITY POLYETHYLENE. Industrial & Engineering Chemistry Research.
30(8), 1841-1846.
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BEDNARSKI, W., JEDRYCHOWSKI, L., HAMMOND, E. G., & NIKOLOV, Z. L.
(1989).
A METHOD FOR THE DETERMINATION OF ALPHA-DICARBONYL COMPOUNDS. Journal of Dairy Science.
72(10), 2474-2477.
-
Nikolov, Z. L., Meagher, M. M., & Reilly, P. J.
(1989).
Kinetics, equilibria, and modeling of the formation of oligosaccharides from D‐glucose with Aspergillus niger glucoamylases I and II. Biotechnology and Bioengineering.
34(5), 694-704.
-
Meagher, M. M., Nikolov, Z. L., & Reilly, P. J.
(1989).
Subsite mapping of Aspergillus niger glucoamylases I and II with malto‐ and isomaltooligosaccharides. Biotechnology and Bioengineering.
34(5), 681-688.
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JAKOVLJEVIC, J. B., NIKOLOV, Z. L., & BOSKOV, Z. M.
(1986).
SOME ANALYTICAL ASPECTS OF ENZYME DEGRADATION OF STARCH AND INULIN INTO MALTOOLIGOSACCHARIDE AND FRUCTOOLIGOSACCHARIDE. NAHRUNG-FOOD.
30(2), 171-176.
-
NIKOLOV, Z. L., MEAGHER, M. M., & REILLY, P. J.
(1985).
HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF DISACCHARIDES ON AMINE-BONDED SILICA COLUMNS. 319(1), 51-57.
-
NIKOLOV, Z. L., MEAGHER, M. M., & REILLY, P. J.
(1985).
HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF TRISACCHARIDES ON AMINE-BONDED SILICA COLUMNS. 321(2), 393-399.
-
NIKOLOV, Z. L., & REILLY, P. J.
(1985).
RETENTION OF CARBOHYDRATES ON SILICA AND AMINE-BONDED SILICA STATIONARY PHASES - APPLICATION OF THE HYDRATION MODEL. 325(1), 287-293.
-
NIKOLOV, Z. L., JAKOVLJEVIC, J. B., & BOSKOV, Z. M.
(1984).
HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF OLIGOSACCHARIDES USING AMINE MODIFIED SILICA COLUMNS. Starch.
36(3), 97-100.
-
NIKOLOV, Z. L., & REILLY, P. J.
(1983).
ISOTHERMAL CAPILLARY COLUMN GAS-CHROMATOGRAPHY OF TRIMETHYLSILYL DISACCHARIDES. 254(JAN), 157-162.
-
Soto-Sierra, L., Wilken, L. R., Mallawarachchi, S., & Nikolov, Z. L.
(2021).
Process development of enzymatically-generated algal protein hydrolysates for specialty food applications. Algal Research.
55, 102248-102248.
-
chapter
-
Nikolov, Z. L., Regan, J. T., Dickey, L. F., & Woodard, S. L.
(2017).
Purification of Monoclonal Antibodies From Plants. Gottschalk, U. (Eds.),
Process Scale Purification of Antibodies, Second Edition.
(pp. 631-653).
Wiley.
-
Wilken, L. R., & Nikolov, Z. L.
(2016).
Aqueous Fractionation of Dry-Milled Corn Germ for Food Protein Production. Nedović, V., Raspor, P., Lević, J., Tumbas Šaponjac, V., & Barbosa-Cánovas, G. V. (Eds.),
Emerging and Traditional Technologies for Safe, Healthy and Quality Food.
(pp. 443-461).
Springer International Publishing.
-
Nikolov, Z., & Woodard, S. L.
(2014).
Bioseparation: Proteins. Encyclopedia of Agricultural, Food, and Biological Engineering, Second Edition.
-
Wilken, L. R., & Nikolov, Z. L.
(2012).
Downstream Processing of Transgenic Plant Systems: Protein Recovery and Purification Strategies. MOLECULAR FARMING IN PLANTS: RECENT ADVANCES AND FUTURE PROSPECTS.
(pp. 217-257).
Springer Nature.
-
Nikolov, Z. L., Regan, J. T., Dickey, L. F., & Woodard, S. L.
(2009).
Purification of Antibodies From Transgenic Plants. Process Scale Purification of Antibodies.
(pp. 387-406).
Wiley.
-
Nikolov, Z. L., & Fuentes-Granados, R.
(1999).
Soybean (Fermentation, Meal Oil). Encyclopedia of Bioprocess Technology.
Wiley.
-
Evangelista, R. L., & Nikolov, Z. L.
(1996).
Recovery and Purification of Lactic Acid from Fermentation Broth by Adsorption. Seventeenth Symposium on Biotechnology for Fuels and Chemicals.
(pp. 471-480).
Springer Nature.
-
NIKOLOV, ., MAHESHWARI, P., HARDWICK, J. E., MURPHY, P. A., & JOHNSON, L. A.
(1992).
Potential Applications for Supercritical Carbon Dioxide Separations in Soybean Processing. Developments in Food Science.
Food Science and Human Nutrition.
(pp. 595-616).
Elsevier.
-
Nikolov, Z. L., & Reilly, P. J.
(1991).
Enzymatic Depolymerization of Starch. Biocatalysts for Industry.
(pp. 37-62).
Springer Nature.
-
Nikolov, Z. L., Regan, J. T., Dickey, L. F., & Woodard, S. L.
(2017).
Purification of Monoclonal Antibodies From Plants. Gottschalk, U. (Eds.),
Process Scale Purification of Antibodies, Second Edition.
(pp. 631-653).
Wiley.
-
conference paper
-
Kulkarni, S. V., & Nikolov, Z. L.
(2017).
Selective extraction of carotenoids and proteins from Chlorella vulgaris
-
Wilson, K., Munjal, N., Gregory, J. A., Mayfield, S. P., & Nikolov, Z. L.
(2014).
Production and recovery of multimeric malaria antigen (Pfs 25) complexes from Chlamydomonas reinhardtii chloroplast. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
Wilken, L. R., Ogle, E. T., Nikolov, Z. L., & Lohrmann, T.
(2014).
Corn protein & oil recovery after germ wet milling. 1501-1510.
-
Wilken, L. R., Tran, M., Mayfield, S., & Nikolov, Z. L.
(2012).
Expression and recovery of immunotoxins from Chlamydomonas reinhardtii chloroplast. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
Wilken, L. R., & Nikolov, Z. L.
(2010).
Commercial opportunities and challenges for protein products from corn. 10-22.
-
Barros, G., Woodard, S. L., & Nikolov, Z. L.
(2010).
Removal of phenolic compounds by adsorption on polymeric resins before protein purification. 1259-1267.
-
Wilken, L. R., & Nikolov, Z. L.
(2009).
Effect of phytic acid and buffer ions on recombinant human lysozyme purification. 5673-5681.
-
Nikolov, Z. L., Woodard, S. L., & Barros, G.
(2009).
BIOT 267-Pretreatment of plant extracts containing MAb may be desirable. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
Woodard, S. L., White, S. G., Damaj, M. B., Gonzalez, J., Mirkov, T. E., & Nikolov, Z. L.
(2009).
Evaluation of processing options for transgenic sugarcane tissue expressing bovine lysozyme. 4949-4954.
-
Wilken, L. R., Barros, G., Woodard, S. L., & Nikolov, Z. L.
(2008).
BIOT 211-Evaluation and removal of key plant-derived impurities during downstream process development. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
Wilken, L. R., Woodard, S., Barros, G., White, S., & Nikolov, Z. L.
(2007).
BIOT 251-Host system choice challenges bioprocessing of plant-derived therapeutics. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
Streatfield, S. J., Mayor, J. M., Barker, D. K., Brooks, C., Lamphear, B. J., Woodard, S. L., ... Howard, J. A.
(2002).
2000 Congress Symposium on Molecular Farming: Development of an edible subunit vaccine in corn against enterotoxigenic strains of Escherichia coli. In Vitro Cellular and Developmental Biology: Plant.
11-17.
-
Glatz, C. E., Zhang, C. M., Bai, Y., & Nikolov, Z. L.
(1999).
Processing considerations for use of canola for recombinant protein production. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
U162-U162.
-
Nikolov, Z. L., Kusnadi, A., Evangelista, R., Hood, E. E., & Howard, J. A.
(1998).
Expression and recovery of a recombinant protein from transgenic maize. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
U311-U312.
-
DALMIA, B. K., SCHUTTE, K., THIEM, E. A., & NIKOLOV, Z. L.
(1994).
BETA-GALACTOSIDASE FUSION PROTEINS WITH THE STARCH-BINDING DOMAINS OF GLUCOAMYLASE-I AND CYCLODEXTRIN GLUCANOTRANSFERASE. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
191-BIOT.
-
DALMIA, B., TALADRIZ, L. M., KUSNADI, A., FORD, C., & NIKOLOV, Z. L.
(1991).
EVALUATING STARCH-PROTEIN INTERACTIONS FOR RECOVERY OF RECOMBINANT PROTEINS. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
47-BIOT.
-
NIKOLOV, Z. L.
(1990).
GLUCOAMYLASE IN STARCH BIOPROCESSING. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
63-CELL.
-
DALMIA, B. K., & NIKOLOV, Z. L.
(1990).
BIOSPECIFIC ADSORPTION OF GLUCOAMYLASE-I FROM ASPERGILLUS-NIGER ON RAW STARCH. 87-99.
-
NIKOLOV, Z. L., SELOSSE, E., & REILLY, P. J.
(1984).
KINETICS AND EQUILIBRIA OF REVERSION REACTIONS CATALYZED BY GLUCOAMYLASE. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
35-CARB.
-
Kulkarni, S. V., & Nikolov, Z. L.
(2017).
Selective extraction of carotenoids and proteins from Chlorella vulgaris
-
patent
-
De Figueiredo, P., Li, L., Nikolov, Z., Shaw, B., Dickman, M., Louzada, E., Sturino, J., & Chang, Y.
(2016).
Transformation of glycerol and cellulosic materials into high energy fuels
-
De Figueiredo, P., Li, L., Nikolov, Z., Shaw, B., Dickman, M., Louzada, E., Sturino, J., & Chang, Y.
(2016).
Transformation of glycerol and cellulosic materials into high energy fuels
Research
principal investigator on
- Sustainable bioprocesses for recovery of high-value protein products from plants and microalgae awarded by National Institute of Food and Agriculture - (Washington D.C., District of Columbia, United States) 2018 - 2023
- UNS: Collaborative Research: Nanoengineering Biomimetic Nanobrushes for Pathogen Sensing awarded by National Science Foundation - (Arlington, Virginia, United States) 2015 - 2020
- FFATA: Collaborative Research: Development of an Integrated Algae Platform for Affordable Protein Therapeutic and Vaccine Molecules awarded by National Science Foundation - (Arlington, Virginia, United States) 2012 - 2016
investigator on
Teaching
teaching activities
- BAEN431 Fundamentals In Bioseparations Instructor
- BAEN465 Des Biol Waste Treat Sys Instructor
- BAEN471 Bioreactor Engineering Instructor
- BAEN491 Hnr-research Instructor
- BAEN491 Research Instructor
- BAEN631 Bioprcs Sep Biotec Instructor
- BAEN665 Des Biol Waste Treat Sys Instructor
- BAEN684 Professional Internship Instructor
- BAEN684 Professional Internship Instructor
- BAEN685 Directed Studies Instructor
- BAEN691 Research Instructor
- BIOT684 Directed Prof Internship Instructor
- BIOT684 Directed Prof Internshp Instructor
- BIOT685 Directed Studies Instructor
- BIOT689 Special Topics In Instructor
- BIOT689 Sptp: Biot Lab Techniques Instructor
- BIOT689 Sptp:biomanufacturing Lab Instructor
- CHEN471 Bioreactor Engineering Instructor
- CHEN651 Biochemical Engineerng Instructor
Works By Students
chaired theses and dissertations
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Barros, Georgia (2012-07). Downstream Processing of Recombinant Proteins from Transgenic Plant Systems: Phenolic Compounds Removal from Monoclonal Antibody Expressing Lemna minor and Purification of Recombinant Bovine Lysozyme from Sugarcane.
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Davis, Ryan T. (2012-02). Characterizing Microalgae (Nannochloris oculata) Harvesting by Aluminum Flocculation.
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Garzon Sanabria, Andrea J (2013-07). Bioprocessing of Microalgae for Bioenergy and Recombinant Protein Production.
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Guo, Shengchun (2018-05). Bioprocess Development for Recombinant Therapeutic Protein Osteopontin from Escherichia Coli.
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Imam, Tahmina (2010-01). SEPARATION OF PROTEINS BY ION EXCHANGE AND MEMBRANE CHROMATOGRAPHY: BUFFER COMPOSITION, INTERFERING IMPURITIES AND FOULING CONSIDERATIONS.
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Johnson, Jecori Shana (2018-04). Selective Separation of Proteins Using Stimuli-Responsive Polymers in an Aqueous System.
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Kulkarni, Sayali Vishwas (2018-06). Bioprocessing of Microalgae for Extraction of High-Value Products.
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Kulkarni, Sayali Vishwas (2018-08). Bioprocessing of Microalgae for Extraction of High-Value Products.
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Munjal, Neera (2014-12). Bioprocessing of Microalgae C. reinhardtii for Production and Purification of Single Chain Antibody Fragment.
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Quinones, Katelyn (2015-08). Bioprocessing of Recombinant Proteins Produced in the Chloroplast of Chlamydomonas reinhardtii.
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Ravi, Ayswarya (2019-07). EVALUATION OF MIXED-MODE CHROMATOGRAPHY RESINS FOR ISOLATION OF RECOMBINANT THERAPEUTIC PROTEINS.
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Wilken, Lisa Rachelle (2012-02). Recovery of Recombinant and Native Proteins from Rice and Corn Seed.
Background
education and training
- Ph.D. in Chemical Engineering, Iowa State University - (Ames, Iowa, United States) 1986
- M.S. in Chemical Engineering, Iowa State University - (Ames, Iowa, United States) 1983
- D.E. in Food Engineering, University of Novi Sad - (Novi Sad, Serbia) 1977
awards and honors
Contact
first name
- Zivko
has last name
- Nikolov
mailing address
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Texas A&M University
Biological & Agricultural Engineering
2117 TAMU
College Station, TX 77843-2117
USA
Other
In the News
- znikolov@tamu.edu