Aberrant activation of the biological process, termed epithelial-mesenchymal transition (EMT) plays an important role
in the acquisition of malignant phenotypes as well as cancer stem (CSC) properties by epithelial cancer cells. EMT facilitates the metastatic dissemination which is the major cause of cancer related mortality. The main focus of my work is to identify the molecular mechanisms that induce EMT and to develop novel therapeutic strategies for preventing and treating metastasis.