HR job title
- Instructional Associate Professor
- Contact Info
- ORCiD
- 0000-0003-3266-7988
Yadav, Kamlesh Instructional Associate Professor
Positions
- Instructional Associate Professor, School of Medicine, Health Science Center
Dr. Yadav's primary interest is in translational research, specifically biomarker discoveries and novel therapeutics in cancer (especially prostate) through a combination of biochemistry and genomics. He is also interested in mining EMRs for personalized diagnosis, prognosis and therapeutics using real worlds evidence (RWE) data coupled with machine-learning/AI-algorithms.
Research Areas
- Overview
- Publications
- Background
- Contact
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Overview
Publications
selected publications
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academic article
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Dagar, G., Kumar, R., Yadav, K. K., Singh, M., & Pandita, T. K.
(2023).
Ubiquitination and deubiquitination: Implications on cancer therapy. 1866(4), 194979-194979.
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Das, C., Adhikari, S., Bhattacharya, A., Chakraborty, S., Mondal, P., Yadav, S. S., ... Pandita, T. K.
(2023).
Epigenetic-Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer. Cancer Research.
83(5), 657-666.
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Koyilot, M. C., Natarajan, P., Hunt, C. R., Sivarajkumar, S., Roy, R., Joglekar, S., ... Yadav, K. K.
(2022).
Breakthroughs and Applications of Organ-on-a-Chip Technology. Cells.
11(11), 1828-1828.
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Chakravarty, D., Ratnani, P., Huang, L. i., Dovey, Z., Sobotka, S., Berryhill, R., ... Tewari, A. K.
(2022).
Association between Incidental Pelvic Inflammation and Aggressive Prostate Cancer. Cancers.
14(11), 2734-2734.
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Roy, R., Marakkar, S., Vayalil, M. P., Shahanaz, A., Anil, A. P., Kunnathpeedikayil, S., ... Yadav, K. K.
(2022).
Drug-food Interactions in the Era of Molecular Big Data, Machine Intelligence, and Personalized Health. 13(1), 27-50.
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Ayers, K. L., Mullaney, T., Zhou, X., Liu, J. J., Lee, K., Ma, M., ... Chen, R.
(2021).
Analysis of Real-World Data to Investigate the Impact of Race and Ethnicity on Response to Programmed Cell Death-1 and Programmed Cell Death-Ligand 1 Inhibitors in Advanced Non-Small Cell Lung Cancers. The Oncologist.
26(7), e1226-e1239.
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Stockert, J. A., Weil, R., Yadav, K. K., Kyprianou, N., & Tewari, A. K.
(2021).
Pseudouridine as a novel biomarker in prostate cancer. Urologic Oncology: seminars and original investigations.
39(1), 63-71.
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Rayford, W., Beksac, A. T., Alger, J., Alshalalfa, M., Ahmed, M., Khan, I., ... Tewari, A. K.
(2021).
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences. Communications Biology.
4(1), 670.
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Woo, J., Santasusagna, S., Banks, J., Pastor-Lopez, S., Yadav, K., Carceles-Cordon, M., ... Domingo-Domenech, J.
(2020).
Urine Extracellular Vesicle GATA2 mRNA Discriminates Biopsy Result in Men with Suspicion of Prostate Cancer. 204(4), 691-700.
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Hectors, S. J., Cherny, M., Yadav, K. K., Beksa, A. T., Thulasidass, H., Lewis, S., ... Taouli, B.
(2019).
Radiomics Features Measured with Multiparametric Magnetic Resonance Imaging Predict Prostate Cancer Aggressiveness. Investigative urology.
202(3), 498-505.
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Rai, R., Yadav, S. S., Pan, H., Khan, I., O'Connor, J., Alshalalfa, M., ... Yadav, K. K.
(2019).
Epigenetic analysis identifies factors driving racial disparity in prostate cancer. Cancer Reports.
2(2), e1153-e1153.
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Woo, J., Santasusagna, S., Leiby, B., Yadav, K. K., Dominguez-Andres, A., Pippa, R., ... Domingo-Domenech, J.
(2019).
GATA2 exosomal mRNA: A novel urine biomarker for the diagnosis of clinically significant prostate cancer. Journal of Clinical Oncology.
37(7_suppl), 18-18.
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Woo, J., Santasusagna, S., Banks, J., Dominguez-Andres, A., Yadav, K., Pippa, R., ... Domingo-Domenech, J.
(2019).
887P Urine extracellular vesicle GATA2 mRNA alone and in a multigene test predicts initial prostate biopsy result. ANNALS OF ONCOLOGY.
30, v349-v349.
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Mohamed, N. E., Tewari, A. K., & Yadav, K. K.
(2019).
Development and validation of a polygenic hazard score for aggressive prostate cancer identification. Translational cancer research.
8(Suppl 2), S124-S125.
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Murillo, O. D., Thistlethwaite, W., Rozowsky, J., Subramanian, S. L., Lucero, R., Shah, N., ... Milosavljevic, A.
(2019).
exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids. Cell.
177(2), 463-477.e15.
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Stockert, J. A., Gupta, A., Herzog, B., Yadav, S. S., Tewari, A. K., & Yadav, K. K.
(2019).
Predictive value of pseudouridine in prostate cancer. American journal of clinical and experimental urology.
7(4), 262-272.
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Smith, J. T., Wunsch, B. H., Dogra, N., Ahsen, M. E., Lee, K., Yadav, K. K., ... Gifford, S. M.
(2018).
Integrated nanoscale deterministic lateral displacement arrays for separation of extracellular vesicles from clinically-relevant volumes of biological samples. Lab on a Chip.
18(24), 3913-3925.
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Hieronymus, H., Murali, R., Tin, A., Yadav, K., Abida, W., Moller, H., ... Sawyers, C. L.
(2018).
Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death. eLife.
7, e37294.
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Yadav, K. K.
(2018).
How AI Is Optimizing the Detection and Management of Prostate Cancer. IEEE Pulse.
9(5), 19-19.
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Yadav, S. S., Stockert, J. A., Hackert, V., Yadav, K. K., & Tewari, A. K.
(2018).
Intratumor heterogeneity in prostate cancer. Urologic Oncology: seminars and original investigations.
36(8), 349-360.
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Beksac, A. T., Cumarasamy, S., Falagario, U., Xu, P., Takhar, M., Alshalalfa, M., ... Tewari, A.
(2018).
Multiparametric Magnetic Resonance Imaging Features Identify Aggressive Prostate Cancer at the Phenotypic and Transcriptomic Level. 200(6), 1241-1249.
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Rayford, W., Alger, J., Takhar, M., Jordan, J., Yadav, K., Alshalalfa, M., ... Tewari, A.
(2018).
PD56-01 COMPARATIVE GENOMIC ANALYSIS OF 1,043 AFRICAN AMERICAN AND NON-AFRICAN AMERICAN PROSTATE CANCERS: A REPORT FROM THE DECIPHER GRID COLLABORATIVE. Investigative urology.
199(4), e1062.
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Olsson, C. A., Lavery, H. J., Yadav, K. K., Anderson, A. E., & Kapoor, D.
(2018).
Histologic Changes in Prostate Cancer Detected Subsequent to the 2012 United States Preventive Services Task Force (USPSTF) Prostate Cancer Screening Recommendation. Reviews in urology.
20(3), 125-130.
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Yadav, S. S., Li, J., Stockert, J. A., Herzog, B., O'Connor, J., Garzon-Manco, L., ... Yadav, K. K.
(2017).
Induction of Neuroendocrine Differentiation in Prostate Cancer Cells by Dovitinib (TKI-258) and its Therapeutic Implications. Transl Oncol.
10(3), 357-366.
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Yadav, K. K., Shameer, K., Yadav, S. S., Elaiho, C., Li, L. i., O'Connor, J., ... Tewari, A.
(2017).
MP14-08 A MULTISCALE SURVEY OF INFLAMMATORY DISEASES AND PROSTATE ONCOPHENOTYPES. Investigative urology.
197(4), e164-e165.
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Stockert, J., Yadav, S. S., Tewari, A., & Yadav, K. K.
(2017).
MP33-09 CLINICAL UTILITY OF PSEUDOURIDINE AS A DIAGNOSTIC MARKER TO DETECT PROSTATE CANCER. Investigative urology.
197(4), e420.
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Rai, R., Elaiho, C., Hackert, V., Yadav, K. K., Tewari, A., & Yadav, S. S.
(2017).
MP87-09 DISTINCT EPIGENETIC AND TRANSCRIPTOMIC VARIATIONS IN AFRICAN AMERICAN MEN AS COMPARED TO CAUCASIAN IN PROSTATE CANCER. Investigative urology.
197(4), e1169.
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Yadav, K. K., Shameer, K., Stockert, J., Elaiho, C., Readhead, B., Yadav, S. S., Dudley, J., & Tewari, A.
(2017).
PD37-10 BIOCHEMICAL VALIDATION OF PIPERLONGUMINE AS A POTENT THERAPEUTIC AGAINST NEUROENDOCRINE PROSTATE CANCER. Investigative urology.
197(4), e677-e678.
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Alford, A. V., Brito, J. M., Yadav, K. K., Yadav, S. S., Tewari, A. K., & Renzulli, J.
(2017).
The Use of Biomarkers in Prostate Cancer Screening and Treatment. Reviews in urology.
19(4), 221-234.
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Yadav, K. K., Shameer, K., Readhead, B., Yadav, S. S., Li, L. i., Kasarskis, A., Tewari, A. K., & Dudley, J. T.
(2016).
Systems Medicine Approaches to Improving Understanding, Treatment, and Clinical Management of Neuroendocrine Prostate Cancer. Current Pharmaceutical Design.
22(34), 5234-5248.
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Yadav, S. S., Li, J., Stockert, J. A., O'Connor, J., Herzog, B., Elaiho, C., ... Yadav, K. K.
(2016).
Combination effect of therapies targeting the PI3K- and AR-signaling pathways in prostate cancer. Oncotarget.
7(46), 76181-76196.
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Yadav, S. S., Li, J., Herzog, B., Stockert, J., O'Connor, J., Manco, L. G., ... Yadav, K. K.
(2016).
MP90-11 INDUCTION OF NEUROENDOCRINE DIFFERENTIATION IN PROSTATE CANCER CELLS BY DOVITINIB (TKI-258) AND ITS ASSOCIATED THERAPEUTIC IMPLICATIONS. Investigative urology.
195(4), e1148-e1149.
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Christensen, S. M., Tu, H., Jun, J. E., Alvarez, S., Triplet, M. G., Iwig, J. S., ... Groves, J. T.
(2016).
One-way membrane trafficking of SOS in receptor-triggered Ras activation. Nature Structural and Molecular Biology.
23(9), 838-846.
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Li, J., Yadav, S. S., O'Connor, J., Herzog, B., Elaiho, C., Yadav, K. K., & Tewari, A. K.
(2016).
PD32-09 COMBINATION EFFECT OF THERAPIES TARGETING THE PI3K-MTOR AND AR SIGNALING PATHWAYS IN PROSTATE CANCER. Investigative urology.
195(4), e764.
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Yadav, S. S., Li, J., Lavery, H. J., Yadav, K. K., & Tewari, A. K.
(2015).
Next-generation sequencing technology in prostate cancer diagnosis, prognosis, and personalized treatment. Urologic Oncology: seminars and original investigations.
33(6), 267.e1-267.13.
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Patgiri, A., Yadav, K. K., Arora, P. S., & Bar-Sagi, D.
(2011).
An orthosteric inhibitor of the Ras-Sos interaction. Nature Chemical Biology.
7(9), 585-587.
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Yadav, K. K., & Bar-Sagi, D.
(2010).
Allosteric gating of Son of sevenless activity by the histone domain. Proceedings of the National Academy of Sciences of the United States of America.
107(8), 3436-3440.
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Yadav, K. K., & BarSagi, D.
(2009).
Histonefolds: A novel membraneanchoring domain in Son of Sevenless. The FASEB Journal.
23(S1), 697.1-697.1.
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Tartaglia, M., Pennacchio, L. A., Zhao, C., Yadav, K. K., Fodale, V., Sarkozy, A., ... Gelb, B. D.
(2007).
Erratum: Corrigendum: Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome. Nature Genetics.
39(2), 276-276.
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Tartaglia, M., Pennacchio, L. A., Zhao, C., Yadav, K. K., Fodale, V., Sarkozy, A., ... Gelb, B. D.
(2007).
Gain-of-function SOS1 mutations cause a distinctive form of Noonan syndrome. Nature Genetics.
39(1), 75-79.
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Dagar, G., Kumar, R., Yadav, K. K., Singh, M., & Pandita, T. K.
(2023).
Ubiquitination and deubiquitination: Implications on cancer therapy. 1866(4), 194979-194979.
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chapter
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Tewari, A. K., Stockert, J. A., Yadav, S. S., Yadav, K. K., & Khan, I.
(2018).
Inflammation and Prostate Cancer. Advances in Experimental Medicine and Biology.
Cell & Molecular Biology of Prostate Cancer.
(pp. 41-65).
Springer Nature.
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Tewari, A. K., Stockert, J. A., Yadav, S. S., Yadav, K. K., & Khan, I.
(2018).
Inflammation and Prostate Cancer. Advances in Experimental Medicine and Biology.
Cell & Molecular Biology of Prostate Cancer.
(pp. 41-65).
Springer Nature.
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conference paper
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Ma, M., Zhou, X., Goldsweig, H., Hahner, N., Han, D., Dietz, M., ... Chen, R.
(2019).
Analysis of real-world data (RWD) on treatment (tx) sequencing in patients with advanced non-small cell lung cancer (aNSCLC). Journal of Clinical Oncology.
e20642-e20642.
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Liu, Z., Ma, M., Grover, K., Li, L. i., Goldsweig, H., Yadav, K., ... Chen, R.
(2019).
Investigating racial differences in treatment responses through analysis of real-world data (RWD). Journal of Clinical Oncology.
e18141-e18141.
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Woo, J., Santasusagna, S., Banks, J., Dominguez-Andres, A., Yadav, K., Pippa, R., ... Domingo-Domenech, J.
(2019).
Urine extracellular vesicle GATA2 mRNA alone and in a multigene test predicts initial prostate biopsy result. ANNALS OF ONCOLOGY.
-
Yadav, K. K., Shameer, K., Stockert, J. A., Elaiho, C., Readhead, B., Yadav, S. S., Dudley, J., & Tewari, A. K.
(2018).
Abstract B023: Identification and biochemical validation of piperlongumine as a potent therapeutic against neuroendocrine prostate cancer. Cancer Research.
b023-b023.
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Yadav, K. K., Shameer, K., Readhead, B., Stockert, J. A., Elaiho, C., Yadav, S. S., ... Dudley, J. T.
(2017).
Abstract 3250: Computational drug repositioning and biochemical validation of piperlongumine as a potent therapeutic agent for neuroendocrine prostate cancer. Cancer Research.
3250-3250.
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Shameer, K., Yadav, K. K., Li, L. i., Yadav, S. S., Glicksberg, B., Khan, I., ... Tewari, A. K.
(2017).
Abstract 3772: A multi-scale survey to assess the impact of inflammatory diseases of the abdominal cavity and prostate cancer severity. Cancer Research.
3772-3772.
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Ma, M., Zhou, X., Goldsweig, H., Hahner, N., Han, D., Dietz, M., ... Chen, R.
(2019).
Analysis of real-world data (RWD) on treatment (tx) sequencing in patients with advanced non-small cell lung cancer (aNSCLC). Journal of Clinical Oncology.
e20642-e20642.
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institutional repository document
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Mehaboob, A. K., Natarajan, P. D., Vayalil, M. P., Marakkar, S., Koyilot, M. C., Shameer, K., & Yadav, K. K.
(2022).
A Novel Design For A COVID-19 Diagnosis System Using Machine Learning And Drone Technology (COVIDRONE-20)
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Dogra, N., Ahsen, M. E., Kozlova, E. E., Chen, T., Allette, K., Olsen, R., ... Stolovitzky, G.
(2020).
exRNA Signatures in Extracellular Vesicles and their Tumor-Lineage from Prostate Cancer
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Rai, R., Yadav, S. S., Pan, H., OConnor, J., Alshalalfa, M., Davicioni, E., ... Yadav, K. K.
(2018).
Epigenetic analysis identifies factors driving racial disparity in prostate cancer
-
Mehaboob, A. K., Natarajan, P. D., Vayalil, M. P., Marakkar, S., Koyilot, M. C., Shameer, K., & Yadav, K. K.
(2022).
A Novel Design For A COVID-19 Diagnosis System Using Machine Learning And Drone Technology (COVIDRONE-20)
Background
education and training
- Ph.D. in Cell and Molecular Biology, New York University School of Medicine - (New York, New York, United States) 2010
- M.Tech. in Environmental Engineering and Management, Indian Institute of Technology Kanpur - (Kanpur, Uttar Pradesh, India) 2003
- M.Sc. in Biochemistry, Banaras Hindu University - (Varanasi, Uttar Pradesh, India) 2001
- Memorial Sloan Kettering Cancer Center - (New York, New York, United States) , Postdoctoral Training 2014
Contact
first name
- Kamlesh
has last name
- Yadav
Other
- kamlesh.yadav@tamu.edu