HR job title
- Professor
- Contact Info
- 1 979 458 3110
Myles, Kevin Professor
Positions
- Associate Professor, Entomology, College of Agriculture and Life Sciences
- Overview
- Publications
- Research
- Teaching
- Background
- Contact
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Overview
Publications
selected publications
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academic article
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Khan, S. A., Eggleston, H., Myles, K. M., & Adelman, Z. N.
(2019).
Differentially and Co-expressed Genes in Embryo, Germ-Line and Somatic Tissues of Tribolium castaneum. G3: Genes, Genomes, Genetics.
9(7), 2363-2373.
-
Zapletal, J., Gupta, H., Erraguntla, M., Adelman, Z. N., Myles, K. M., & Lawley, M. A.
(2019).
Predicting aquatic development and mortality rates of Aedes aegypti. PLoS ONE.
14(5), e0217199-e0217199.
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Samuel, G. H., Adelman, Z. N., & Myles, K. M.
(2018).
Antiviral Immunity and Virus-Mediated Antagonism in Disease Vector Mosquitoes. TRENDS IN MICROBIOLOGY.
26(5), 447-461.
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Zapletal, J., Erraguntla, M., Adelman, Z. N., Myles, K. M., & Lawley, M. A.
(2018).
Impacts of diurnal temperature and larval density on aquatic development of Aedes aegypti. PLoS ONE.
13(3), e0194025-e0194025.
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Tsujimoto, H., Anderson, M., Myles, K. M., & Adelman, Z. N.
(2018).
Identification of Candidate Iron Transporters From the ZIP/ZnT Gene Families in the Mosquito Aedes aegypti. Frontiers in Physiology.
9(APR), 380.
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Adelman, Z. N., & Myles, K. M.
(2018).
The C-Type Lectin Domain Gene Family in Aedes aegypti and Their Role in Arbovirus Infection. Viruses.
10(7), 367-367.
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Adelman, Z. N., Pledger, D., & Myles, K. M.
(2017).
Developing standard operating procedures for gene drive research in disease vector mosquitoes. PATHOGENS AND GLOBAL HEALTH.
111(8), 436-447.
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Samuel, G. H., Wiley, M. R., Badawi, A., Adelman, Z. N., & Myles, K. M.
(2016).
Yellow fever virus capsid protein is a potent suppressor of RNA silencing that binds double-stranded RNA. Proceedings of the National Academy of Sciences of the United States of America.
113(48), 13863-13868.
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Myles, K., & Adelman, Z.
(2016).
Editorial overview: Vectors and medical and veterinary entomology: Summary. Current Opinion in Insect Science.
16, v-vi.
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Samuel, G. H., Adelman, Z. N., & Myles, K. M.
(2016).
Temperature-dependent effects on the replication and transmission of arthropod-borne viruses in their insect hosts. Current Opinion in Insect Science.
16, 108-113.
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Haac, M. E., Anderson, M., Eggleston, H., Myles, K. M., & Adelman, Z. N.
(2015).
The hub protein loquacious connects the microRNA and short interfering RNA pathways in mosquitoes. Nucleic Acids Research (NAR).
43(7), 3688-3700.
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Basu, S., Aryan, A., Overcash, J. M., Samuel, G. H., Anderson, M., Dahlem, T. J., Myles, K. M., & Adelman, Z. N.
(2015).
Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti. Proceedings of the National Academy of Sciences of the United States of America.
112(13), 4038-4043.
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Overcash, J. M., Aryan, A., Myles, K. M., & Adelman, Z. N.
(2015).
Understanding the DNA damage response in order to achieve desired gene editing outcomes in mosquitoes. Chromosome Research: the international journal for all aspects of chromosome and nuclear biology.
23(1), 31-42.
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O'Neal, S. T., Samuel, G. H., Adelman, Z. N., & Myles, K. M.
(2014).
Mosquito-borne viruses and suppressors of invertebrate antiviral RNA silencing. Viruses.
6(11), 4314-4331.
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Allen, W. J., Wiley, M. R., Myles, K. M., Adelman, Z. N., & Bevan, D. R.
(2014).
Steered molecular dynamics identifies critical residues of the Nodamura virus B2 suppressor of RNAi. Journal of Molecular Modeling.
20(3), 2092.
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Aryan, A., Myles, K. M., & Adelman, Z. N.
(2014).
Targeted genome editing in Aedes aegypti using TALENs. Methods.
69(1), 38-45.
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Adelman, Z. N., Miller, D. M., & Myles, K. M.
(2013).
Bed bugs and infectious disease: a case for the arboviruses. PLOS Pathogens.
9(8), e1003462-e1003462.
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Aryan, A., Anderson, M., Myles, K. M., & Adelman, Z. N.
(2013).
TALEN-based gene disruption in the dengue vector Aedes aegypti. PLoS ONE.
8(3), e60082-e60082.
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Aryan, A., Anderson, M., Myles, K. M., & Adelman, Z. N.
(2013).
Germline excision of transgenes in Aedes aegypti by homing endonucleases. Scientific Reports.
3(1), 1603.
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Lucas, K. J., Myles, K. M., & Raikhel, A. S.
(2013).
Small RNAs: a new frontier in mosquito biology. Trends in Parasitology.
29(6), 295-303.
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Adelman, Z. N., Anderson, M., Wiley, M. R., Murreddu, M. G., Samuel, G. H., Morazzani, E. M., & Myles, K. M.
(2013).
Cooler temperatures destabilize RNA interference and increase susceptibility of disease vector mosquitoes to viral infection. 7(5), e2239-e2239.
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Adelman, Z. N., Anderson, M., Liu, M., Zhang, L., & Myles, K. M.
(2012).
Sindbis virus induces the production of a novel class of endogenous siRNAs in Aedes aegypti mosquitoes. INSECT MOLECULAR BIOLOGY.
21(3), 357-368.
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Carpenetti, T., Aryan, A., Myles, K. M., & Adelman, Z. N.
(2012).
Robust heat-inducible gene expression by two endogenous hsp70-derived promoters in transgenic Aedes aegypti. INSECT MOLECULAR BIOLOGY.
21(1), 97-106.
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Morazzani, E. M., Wiley, M. R., Murreddu, M. G., Adelman, Z. N., & Myles, K. M.
(2012).
Production of virus-derived ping-pong-dependent piRNA-like small RNAs in the mosquito soma. PLOS Pathogens.
8(1), e1002470-e1002470.
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Wiley, M. R., Roberts, L. O., Adelman, Z. N., & Myles, K. M.
(2010).
Double subgenomic alphaviruses expressing multiple fluorescent proteins using a Rhopalosiphum padi virus internal ribosome entry site element. PLoS ONE.
5(11), e13924-e13924.
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Anderson, M., Gross, T. L., Myles, K. M., & Adelman, Z. N.
(2010).
Validation of novel promoter sequences derived from two endogenous ubiquitin genes in transgenic Aedes aegypti. INSECT MOLECULAR BIOLOGY.
19(4), 441-449.
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Plaskon, N. E., Adelman, Z. N., & Myles, K. M.
(2009).
Accurate strand-specific quantification of viral RNA. PLoS ONE.
4(10), e7468-e7468.
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Myles, K. M., Morazzani, E. M., & Adelman, Z. N.
(2009).
Origins of alphavirus-derived small RNAs in mosquitoes. RNA Biology.
6(4), 387-391.
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Gross, T. L., Myles, K. M., & Adelman, Z. N.
(2009).
Identification and characterization of heat shock 70 genes in Aedes aegypti (Diptera: Culicidae). Journal of Medical Entomology.
46(3), 496-504.
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Myles, K. M., Morazzani, E. M., & Adelman, Z. N.
(2009).
Origins of alphavirus-derived small RNAs in mosquitoes. RNA Biology.
6(4), 387-391.
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Myles, K. M., Wiley, M. R., Morazzani, E. M., & Adelman, Z. N.
(2008).
Alphavirus-derived small RNAs modulate pathogenesis in disease vector mosquitoes. Proceedings of the National Academy of Sciences of the United States of America.
105(50), 19938-19943.
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Adelman, Z. N., Anderson, M., Morazzani, E. M., & Myles, K. M.
(2008).
A transgenic sensor strain for monitoring the RNAi pathway in the yellow fever mosquito, Aedes aegypti. Insect Biochemistry and Molecular Biology.
38(7), 705-713.
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Myles, K. M., Kelly, C., Ledermann, J. P., & Powers, A. M.
(2006).
Effects of an opal termination codon preceding the nsP4 gene sequence in the O'Nyong-Nyong virus genome on Anopheles gambiae infectivity. Journal of Virology.
80(10), 4992-4997.
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Brault, A. C., Foy, B. D., Myles, K. M., Kelly, C., Higgs, S., Weaver, S. C., ... Powers, A. M.
(2004).
Infection patterns of o'nyong nyong virus in the malaria-transmitting mosquito, Anopheles gambiae. INSECT MOLECULAR BIOLOGY.
13(6), 625-635.
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Foy, B. D., Myles, K. M., Pierro, D. J., Sanchez-Vargas, I., Uhlrov, M., Jindra, M., Beaty, B. J., & Olson, K. E.
(2004).
Development of a new Sindbis virus transducing system and its characterization in three Culicine mosquitoes and two Lepidopteran species. INSECT MOLECULAR BIOLOGY.
13(1), 89-100.
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Myles, K. M., Pierro, D. J., & Olson, K. E.
(2004).
Comparison of the transmission potential of two genetically distinct Sindbis viruses after oral infection of Aedes aegypti (Diptera: Culicidae). Journal of Medical Entomology.
41(1), 95-106.
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Myles, K. M., Pierro, D. J., & Olson, K. E.
(2003).
Deletions in the putative cell receptor-binding domain of Sindbis virus strain MRE16 E2 glycoprotein reduce midgut infectivity in Aedes aegypti. Journal of Virology.
77(16), 8872-8881.
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Pierro, D. J., Myles, K. M., Foy, B. D., Beaty, B. J., & Olson, K. E.
(2003).
Development of an orally infectious Sindbis virus transducing system that efficiently disseminates and expresses green fluorescent protein in Aedes aegypti. INSECT MOLECULAR BIOLOGY.
12(2), 107-116.
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de Lara Capurro, M., Coleman, J., Beerntsen, B. T., Myles, K. M., Olson, K. E., Rocha, E., Krettli, A. U., & James, A. A.
(2000).
Virus-expressed, recombinant single-chain antibody blocks sporozoite infection of salivary glands in Plasmodium gallinaceum-infected Aedes aegypti. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE.
62(4), 427-433.
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Olson, K. E., Myles, K. M., Seabaugh, R. C., Higgs, S., Carlson, J. O., & Beaty, B. J.
(2000).
Development of a Sindbis virus expression system that efficiently expresses green fluorescent protein in midguts of Aedes aegypti following per os infection. INSECT MOLECULAR BIOLOGY.
9(1), 57-65.
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Higgs, S., Oray, C. T., Myles, K., Olson, K. E., & Beaty, B. J.
(1999).
Infecting larval arthropods with a chimeric, double subgenomic Sindbis virus vector to express genes of interest. BioTechniques.
27(5), 908-911.
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Khan, S. A., Eggleston, H., Myles, K. M., & Adelman, Z. N.
(2019).
Differentially and Co-expressed Genes in Embryo, Germ-Line and Somatic Tissues of Tribolium castaneum. G3: Genes, Genomes, Genetics.
9(7), 2363-2373.
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chapter
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Adelman, Z. N., Basu, S., & Myles, K. M.
(2016).
Gene Insertion and Deletion in Mosquitoes. GENETIC CONTROL OF MALARIA AND DENGUE.
(pp. 139-168).
Elsevier.
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Adelman, Z. N., Basu, S., & Myles, K. M.
(2016).
Engineering Pathogen Resistance in Mosquitoes. Genetic Control of Malaria and Dengue.
(pp. 277-304).
Elsevier.
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Basu, S., Aryan, A., Haac, M. E., Myles, K. M., & Adelman, Z. N.
(2016).
Methods for TALEN Evaluation, Use, and Mutation Detection in the Mosquito Aedes aegypti. Methods in molecular biology (Clifton, N.J.).
TALENS: METHODS AND PROTOCOLS.
(pp. 157-177).
Springer Nature.
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Adelman, Z. N., Basu, S., & Myles, K. M.
(2016).
Gene Insertion and Deletion in Mosquitoes. GENETIC CONTROL OF MALARIA AND DENGUE.
(pp. 139-168).
Elsevier.
Research
principal investigator on
- NBAF Scientist Training Program (NSTP) awarded by United States Department of Agriculture - (Washington D.C., District of Columbia, United States) 2019 - 2023
- Hierarchical antiviral immunity in disease vector mosquitoes awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2016 - 2020
co-principal investigator on
- Self-eliminating strategy to control gene drive awarded by National Institute of Allergy and Infectious Diseases - (Bethesda, Maryland, United States) 2020 - 2025
- Making Gene Drives Biodegradable awarded by United States Department of Defense - (Washington D.C., District of Columbia, United States) 2016 - 2018
investigator on
- Programmable elimination of gene drive transgenes from an agricultural pest insect awarded by United States Department of Agriculture - (Washington D.C., District of Columbia, United States) 2019 - 2022
- DNA Repair Pathway Choice and Significance in Targeted Genome Editing of Aedes Aegypti awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2018 - 2022
- Identification and disruption of mosquito heme transporters awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2016 - 2018
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- ENTO210 Global Public Health Ent Instructor
- ENTO442 Mosquito Hist Human Survival Instructor
- ENTO489 Sptp: Mosq Virus Vect Control Instructor
- ENTO489 Sptp:mos-borne Vir Vect Con Instructor
- ENTO491 Research Instructor
- ENTO642 Mosquito Hist Human Survival Instructor
- ENTO646 Invertebrate Immunology Instructor
- ENTO689 Sptp: Invertebrate Immunology Instructor
- ENTO691 Research Instructor
- GENE491 Hnr-research Instructor
- GENE691 Research Instructor
Background
education and training
- Ph.D. in Microbiology, Colorado State University - (Fort Collins, Colorado, United States) 2003
- B.S. in Microbiology, Colorado State University - (Fort Collins, Colorado, United States) 1997
Contact
first name
- Kevin
has last name
- Myles
mailing address
-
Texas A&M University
Entomology
2475 TAMU
College Station, TX 77843-2475
USA
Other
In the News
- mylesk@tamu.edu