selected publications academic article Wang, H., Shen, Z., Wu, C., Ji, P., Noh, J. Y., Geoffroy, C. G., ... Sun, Y. (2024). Neuronal ablation of GHSR mitigates diet-induced depression and memory impairment via AMPK-autophagy signaling-mediated inflammation. 15, 1339937. Samtani, G., Kim, S., Michaud, D., Hillhouse, A. E., Szule, J. A., Konganti, K., & Li, J. (2023). Brain region dependent molecular signatures and myelin repair following chronic demyelination. Frontiers in Cellular Neuroscience. 17, 1169786. Kim, S., Lu, H. C., Steelman, A. J., & Li, J. (2022). Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1 production and CD4 T cell activation in autoimmune demyelination. 119(24), e2117636119. Lu, H. C., Kim, S., Steelman, A. J., Tracy, K., Zhou, B., Michaud, D., ... Li, J. (2020). STAT3 signaling in myeloid cells promotes pathogenic myelin-specific T cell differentiation and autoimmune demyelination. 117(10), 5430-5441. Kim, S., Bielawski, J., Yang, H., Kong, Y. u., Zhou, B., & Li, J. (2018). Functional antagonism of sphingosine-1-phosphate receptor 1 prevents cuprizone-induced demyelination. 66(3), 654-669. Jeong, S., Kim, S., Buonocore, J., Park, J., Welsh, C. J., Li, J., & Han, A. (2018). A Three-Dimensional Arrayed Microfluidic Blood-Brain Barrier Model With Integrated Electrical Sensor Array. IEEE Transactions on Biomedical Engineering. 65(2), 431-439. Steelman, A. J., Zhou, Y., Koito, H., Kim, S., Payne, H. R., Lu, Q. R., & Li, J. (2016). Activation of oligodendroglial Stat3 is required for efficient remyelination. 91, 336-346. Kim, S., Park, J., Han, A., & Li, J. (2014). Microfluidic systems for axonal growth and regeneration research. NEURAL REGENERATION RESEARCH. 9(19), 1703-1705. Deng, Y., Kim, B., He, X., Kim, S., Lu, C., Wang, H., ... Lu, Q. R. (2014). Direct visualization of membrane architecture of myelinating cells in transgenic mice expressing membraneāanchored EGFP. 52(4), 341-349. Park, J., Kim, S., Park, S. I., Choe, Y., Li, J., & Han, A. (2014). A microchip for quantitative analysis of CNS axon growth under localized biomolecular treatments. 221, 166-174. Kim, S., Steelman, A. J., Zhang, Y., Kinney, H. C., & Li, J. (2012). Aberrant upregulation of astroglial ceramide potentiates oligodendrocyte injury. 22(1), 41-57. Kim, S., Steelman, A. J., Koito, H., & Li, J. (2011). Astrocytes promote TNF-mediated toxicity to oligodendrocyte precursors. 116(1), 53-66. Kim, S., Dayani, L., Rosenberg, P. A., & Li, J. (2010). RIP1 kinase mediates arachidonic acid-induced oxidative death of oligodendrocyte precursors. 2(2), 137-147. Yune, T. Y., Lee, J. Y., Jung, G. Y., Kim, S. J., Jiang, M. H., Kim, Y. C., ... Oh, T. H. (2007). Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury. Journal of Neuroscience. 27(29), 7751-7761. Kim, S. J., Yune, T. Y., Han, C. T., Kim, Y. C., Oh, Y. J., Markelonis, G. J., & Oh, T. H. (2007). Mitochondrial isocitrate dehydrogenase protects human neuroblastoma SH-SY5Y cells against oxidative stress. Journal of Neuroscience Research. 85(1), 139-152. Yune, T. Y., Lee, S. M., Kim, S. J., Park, H. K., Oh, Y. J., Kim, Y. C., Markelonis, G. J., & Oh, T. H. (2004). Manganese superoxide dismutase induced by TNF-beta is regulated transcriptionally by NF-kappaB after spinal cord injury in rats. JOURNAL OF NEUROTRAUMA. 21(12), 1778-1794. Lee, S. M., Yune, T. Y., Kim, S. J., Kim, Y. C., Oh, Y. J., Markelonis, G. J., & Oh, T. H. (2004). Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following iNOS/NO induction by lipopolysaccharide in neuron/glia co-cultures. Journal of Neurochemistry. 91(3), 568-578. Yune, T. Y., Kim, S. J., Lee, S. M., Lee, Y. K., Oh, Y. J., Kim, Y. C., Markelonis, G. J., & Oh, T. H. (2004). Systemic administration of 17beta-estradiol reduces apoptotic cell death and improves functional recovery following traumatic spinal cord injury in rats. JOURNAL OF NEUROTRAUMA. 21(3), 293-306. Lee, S. M., Yune, T. Y., Kim, S. J., Park, D. W., Lee, Y. K., Kim, Y. C., ... Oh, T. H. (2003). Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat. JOURNAL OF NEUROTRAUMA. 20(10), 1017-1027. Yune, T. Y., Chang, M. J., Kim, S. J., Lee, Y. B., Shin, S. W., Rhim, H., ... Oh, T. H. (2003). Increased production of tumor necrosis factor-alpha induces apoptosis after traumatic spinal cord injury in rats. JOURNAL OF NEUROTRAUMA. 20(2), 207-219. Kim, S., Lee, J., & Ahnn, J. (2000). Analysis of the fit-1 gene encoding a ECM protein, flectin, in Caenorhabditis elegans. 10(2), 226-231. chapter Park, J., Kim, S., Li, J., & Han, A. (2015). Multi-compartment Neuron-Glia Coculture Microsystem. Neuromethods. Biffi, E. (Eds.), MICROFLUIDIC AND COMPARTMENTALIZED PLATFORMS FOR NEUROBIOLOGICAL RESEARCH. (pp. 149-159). Springer Nature. Park, J., Kim, S., Li, J., & Han, A. (2014). Axon length quantification microfluidic culture platform for growth and regeneration study. Methods in molecular biology (Clifton, N.J.). Murray, A. J. (Eds.), AXON GROWTH AND REGENERATION: METHODS AND PROTOCOLS. (pp. 85-95). Springer Nature. conference paper Jeong, S. H., Kim, S., Buonocore, J., Park, J., Welsh, C. J., Li, J., & Han, A. (2016). A multi-channel in vitro blood-brain barrier model. 493-494. Park, J., Kim, S., Li, J., & Han, A. (2014). Brain-on-a-chip: An in vitro myelination model. 150-152.
co-principal investigator on Uncovering BIN1 functions in myelin-producing oligodendrocytes awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2021 - 2023
investigator on Role of glial sphingolipid ceramide in aging and Alzheimers disease awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2024 - 2028 Role of Caspase-8 in Neuroinflammation, Demyelination and Myelin Repair awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2015 - 2018
education and training Ph.D. in Neurobiology, Sogang University - (Seoul, South Korea) 2006 M.S. in Developmental Genetics, Gwangju Institute of Science and Technology - (Gwangju, South Korea) 2000 B.S. in Molecular Biology, Dankook University - (Cheonan, South Korea) 1998 Texas A&M University - (College Station, Texas, United States) , Postdoctoral Training 2010 Kyung Hee University - (Seoul, South Korea) , Postdoctoral Training 2008
mailing address TIGSS Business Office Rm# 440, Reynold Medical Bldg, 206 Olsen Blvd, 2470 TAMU College Station, TX 77843 USA