Cancer Research
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Abstract 5276: Immunomodulatory activity of intermittent low-dose erlotinib plus sulindac: Implications for hereditary and sporadic colorectal cancer.
84:5276-5276.
2024
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Abstract 1231: A stochastic data-driven model predicts the timing and distribution of the epithelial-mesenchymal transition.
83:1231-1231.
2023
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Abstract 2847: Concurrent inactivation of PI3K and PLK1 is synergistic and overcomes acquired resistance to PI3K inhibitors in NOTCH1 MUT HNSCC.
83:2847-2847.
2023
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Abstract 3443: Aryl hydrocarbon receptor and its ligands influence the formation of colonic tertiary lymphoid tissues.
83:3443-3443.
2023
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Abstract 453: Targeting FOXL2C402G vulnerabilities in adult type ovarian granulosa cell tumors.
83:453-453.
2023
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Abstract 4994: Crizotinib enhances the efficacy of BX-795 identified by high-throughput screening of pan-active drugs in colorectal cancer cells.
83:4994-4994.
2023
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Epigenetic-Metabolic Interplay in the DNA Damage Response and Therapeutic Resistance of Breast Cancer..
83:657-666.
2023
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Abstract P6-07-01: Costs of breast cancer recurrence after initial treatment for high risk early breast cancer using SEER-Medicare linked data.
83:p6-07-01-p6-07-01.
2023
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Abstract P6-10-19: Screening of GPCR-targeting drugs for repositioning in breast cancer.
83:p6-10-19-p6-10-19.
2023
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Abstract 236: Nuclear receptor 4A1 ligands target T-cell exhaustion in colorectal cancer.
82:236-236.
2022
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Abstract 5631: Immunomodulatory activity of sulindac plus erlotinib for colon cancer prevention in familial adenomatous polyposis.
82:5631-5631.
2022
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Abstract 5632: Combinatorial epigenetic targeting of PRC2 complexes upregulates MHC antigen presentation components in melanoma and gastrointestinal cancer cells.
82:5632-5632.
2022
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Abstract 5712: Dietary polyphenols as BRD7 and 9 inhibitors for cancer interception.
82:5712-5712.
2022
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Abstract 5713: Alternative splicing of the chromatin modifier gene BAZ1A in colorectal cancer.
82:5713-5713.
2022
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Abstract 5815: Metabolomics in an Apc-mutant genetic background: Mechanistic insights from acute vs. chronic spinach intake.
82:5815-5815.
2022
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Abstract 1858: Rb deficient HPV+ HNSCC experienced enhanced sensitivity to aurora kinase inhibitors by altering the balance of MAD2 and TRIP13 levels.
82:1858-1858.
2022
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Abstract 410: Development of novel, non-toxic rifamycins that reverse drug resistance.
82:410-410.
2022
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Abstract 819: ERBB4 mediates IL10-induced growth of EGFR-independent colon tumors.
82:819-819.
2022
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Abstract GS1-09: Inhibition of GPX4 induces preferential death of p53-mutant triple-negative breast cancer cells.
82:gs1-09-gs1-09.
2022
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Abstract 1553: Intratumoral delivery of STING agonist results in radiographic response in spontaneous canine high-grade glioma.
81:1553-1553.
2021
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Abstract 2106: Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells.
81:2106-2106.
2021
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Abstract 368: Aurora kinase inhibitors cause cell death in HPV+ cells: A plausible treatment option for HPV+ cancers.
81:368-368.
2021
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Abstract 369: Identification of pathways that enhance cell death in NOTCH1-mutant HNSCC.
81:369-369.
2021
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Transient Activation of the Hedgehog-Gli Pathway Rescues Radiotherapy-Induced Dry Mouth via Recovering Salivary Gland Resident Macrophages..
80:5531-5542.
2020
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Abstract 1: Sulindac plus phospholipid is effective for polyp reduction and safer than sulindac alone.
80:1-1.
2020
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A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity..
80:1011-1023.
2020
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Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis..
80:163-169.
2020
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Abstract 1662: In vivo drug response evaluation in anaplastic thyroid cancer patient-derived tumor xenografts following high-throughput screening.
80:1662-1662.
2020
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Abstract A10: Fusobacteria upregulates PD-L1 in head and neck cancer cell lines: Potential mechanism for immune evasion.
80:a10-a10.
2020
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Abstract P3-03-08: Identification of drugs that induce the death or suppress the growth of p53-mutant breast cancer.
80:p3-03-08-p3-03-08.
2020
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Abstract 1195: Stochastic co-evolution of the adaptive immune system and an evading cancer population.
79:1195-1195.
2019
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Abstract 2783: OMICS analysis of breast cancer PDX tumors to determine CTC-cluster-specific signature in predicting breast cancer metastasis.
79:2783-2783.
2019
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CCAR2 acetylation establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition.
79:2614-2614.
2019
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Overcoming therapy resistance in stem cell-rich triple negative breast cancer through p38 MAP kinase inhibition.
79:4669-4669.
2019
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Spleen Tyrosine Kinase-Mediated Autophagy Is Required for Epithelial-Mesenchymal Plasticity and Metastasis in Breast Cancer..
79:1831-1843.
2019
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Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition..
79:918-927.
2019
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Abstract 2824: Modulation of oral cancer cells survival and invasiveness by fusobacteria.
79:2824-2824.
2019
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Abstract LB-320: PPTC testing of an OLIG2 inhibitor CT-179 in patient-derived orthotopic xenograft mouse models of pediatric GBM.
79:lb-320-lb-320.
2019
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Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer..
78:4459-4470.
2018
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Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition..
78:3899-3912.
2018
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Immuno-modulation of macrophages by ovarian cancer stem cells in an in vitro 3D spheroid platform.
78:118-118.
2018
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Abstract 2945: Arsenic trioxide sensitizes glioma stem cells to brain penetrant PI3K and mTOR inhibitor GDC-0084.
78:2945-2945.
2018
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Abstract 4819: High-throughput screening of glioma stem-like cells (GSCs) identifies synergistic therapeutic combination of FGFR inhibitor and CDK4/6 inhibitor.
78:4819-4819.
2018
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Abstract 5139: F. nucleatum induces invasive phenotypes in oral cancer cells in vitro.
78:5139-5139.
2018
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Abstract LB-041: Establishment and characterization of patient derived orthotopic xenograft mouse models representing a serial of primary and recurrent pediatric brain tumors.
78:lb-041-lb-041.
2018
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HNF1B Loss Exacerbates the Development of Chromophobe Renal Cell Carcinomas..
77:5313-5326.
2017
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Abstract 563: Quantitative EMT expression score for predicting survival outcome.
77:563-563.
2017
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Abstract 576: Neoadjuvant immunotherapy improves efficacy of image-guided thermal ablation to generate curative responses in a murine breast cancer model.
77:576-576.
2017
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Prevention by tolfenamic acid and characterization of the molecular targets in Pirc and FAP colorectal adenomas.
77:2229-2229.
2017
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PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1..
77:732-741.
2017
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Abstract 1244: An in vitro biological assay to identify small molecule upregulators of let-7 miRNA in LIN28- positive ovarian cancer cells.
77:1244-1244.
2017
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Abstract 4214: Identification of personalized active agents in pediatric gliomas through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft (PDOX) neurosphere and monolayer cells.
77:4214-4214.
2017
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Novel polypectomy system in a preclinical model of colon cancer.
76:839-839.
2016
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Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer..
75:5392-5397.
2015
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ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas..
75:1035-1045.
2015
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The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development..
74:38-43.
2014
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Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and -catenin..
73:5473-5484.
2013
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FGFR1 is essential for prostate cancer progression and metastasis..
73:3716-3724.
2013
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FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer..
73:1981-1992.
2013
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In vivo diagnosis of melanoma and nonmelanoma skin cancer using oblique incidence diffuse reflectance spectrometry..
72:2738-2745.
2012
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Different expression of AHCYL1 affecting ovarian carcinogenesis between chickens and women.
72:4007-4007.
2012
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Ultrasound increases nanoparticle delivery by reducing intratumoral pressure and increasing transport in epithelial and epithelial-mesenchymal transition tumors..
72:1485-1493.
2012
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Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis..
71:7537-7546.
2011
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Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: Effect of a chemoprotective diet.
71:1160-1160.
2011
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Activation of Toll-like receptor 5 on breast cancer cells by flagellin suppresses cell proliferation and tumor growth..
71:2466-2475.
2011
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Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk..
71:2098-2107.
2011
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Abstract 1379: High throughput screening to identify molecules that alter VHL stability.
71:1379-1379.
2011
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Singleminded-2s (Sim2s) Promotes Breast Tumor Cell Differentiation and Inhibits Metastasis in MCF10DCIS.COM Cells.
70:p4-06-06-p4-06-06.
2010
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Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth..
70:6824-6836.
2010
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Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia..
70:4949-4960.
2010
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Abstract 582: Targeting the blood-brain barrier with a non-canonical iron-mimicry mechanism: A translational approach for the detection and treatment of human brain tumors.
70:582-582.
2010
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Leptin enhances cholangiocarcinoma cell growth..
68:6752-6761.
2008
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Reduced colitis-associated colon cancer in Fat-1 (n-3 fatty acid desaturase) transgenic mice..
68:3985-3991.
2008
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Serotonin Metabolism Is Dysregulated in Cholangiocarcinoma, which Has Implications for Tumor Growth.
68:9184-9193.
2008
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Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage..
67:11594-11600.
2007
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The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells..
67:11001-11011.
2007
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Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2+ accumulation..
67:5561-5568.
2007
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Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells..
67:3286-3294.
2007
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Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors..
67:2816-2823.
2007
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Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways..
67:674-683.
2007
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Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway..
67:289-299.
2007
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Activation of human long interspersed nuclear element 1 retrotransposition by benzo(a)pyrene, an ubiquitous environmental carcinogen..
66:2616-2620.
2006
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3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha..
66:2459-2467.
2006
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Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis..
66:1481-1490.
2006
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In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor..
66:755-762.
2006
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Inhibition of bladder tumor growth by 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes: a new class of peroxisome proliferator-activated receptor gamma agonists..
66:412-418.
2006
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High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor..
65:11478-11485.
2005
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gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway..
65:11437-11446.
2005
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Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway..
65:11001-11009.
2005
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Mechanism of cell cycle regulation by FIP200 in human breast cancer cells..
65:6676-6684.
2005
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Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene..
65:6534-6542.
2005
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Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis..
65:887-897.
2005
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Erratum: Nuclear factor-B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma (Cancer Research (September 2004) 64 (6511-6523).
64:8130.
2004
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Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat..
64:6797-6804.
2004
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Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells..
64:6740-6749.
2004
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1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells..
64:5994-6001.
2004
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A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase..
64:5767-5774.
2004
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Interaction of the aryl hydrocarbon receptor ligand 6-methyl-1,3,8-trichlorodibenzofuran with estrogen receptor alpha..
64:2889-2897.
2004
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Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators..
64:1050-1057.
2004
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Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate..
63:8784-8790.
2003
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Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors..
63:4936-4944.
2003
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Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin..
63:1254-1261.
2003
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Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells..
63:958-964.
2003
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Microarray reveals differences in both tumors and vascular specific gene expression in de novo CD5+ and CD5- diffuse large B-cell lymphomas..
63:60-66.
2003
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Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo..
62:5571-5579.
2002
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Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines..
62:2313-2317.
2002
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Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy..
62:1898-1903.
2002
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p53-dependent suppression of uridine phosphorylase gene expression through direct promoter interaction..
61:6899-6905.
2001
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A rare premalignant prostate tumor epithelial cell syndecan-1 forms a fibroblast growth factor-binding complex with progression-promoting ectopic fibroblast growth factor receptor 1..
61:5295-5302.
2001
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Tamoxifen-induced antitumorigenic/antiestrogenic action synergized by a selective aryl hydrocarbon receptor modulator..
61:3902-3907.
2001
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Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity..
61:1100-1106.
2001
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Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis..
61:1138-1143.
2001
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Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.
61:6120-6130.
2001
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Modulation of tumor angiogenesis by stem cell factor..
60:6757-6762.
2000
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Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators..
60:4798-4803.
2000
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Genomic structure, chromosomal mapping, and promoter region analysis of murine uridine phosphorylase gene..
59:4997-5001.
1999
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Estrogen receptor activation via activation function 2 predicts agonism of xenoestrogens in normal and neoplastic cells of the uterine myometrium..
59:3090-3099.
1999
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A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity..
59:336-341.
1999
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High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat..
58:1127-1129.
1998
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Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells..
57:5369-5378.
1997
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Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid..
57:3424-3428.
1997
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Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras..
57:3180-3188.
1997
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A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice..
57:162-168.
1997
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Inhibition of apoptosis in colon tumors induced in the rat by 2-amino-3-methylimidazo[4,5-f]quinoline..
56:4307-4310.
1996
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Retinoid-induced suppression of squamous cell differentiation in human oral squamous cell carcinoma xenografts (line 1483) in athymic nude mice..
55:3183-3191.
1995
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Dietary fat, fiber, and carcinogen alter fecal diacylglycerol composition and mass..
55:2293-2298.
1995
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Anticarcinogenic activity of indole-3-carbinol acid products: ultrasensitive bioassay by trout embryo microinjection..
54:3617-3619.
1994
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Sequence-specific interaction of a conformational domain of p53 with DNA..
53:5361-5364.
1993
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Characterization of the aryl hydrocarbon receptor and aryl hydrocarbon responsiveness in human ovarian carcinoma cell lines..
53:1802-1807.
1993
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Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1..
51:5304-5307.
1991
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Promotion of aflatoxin B1 carcinogenesis by the natural tumor modulator indole-3-carbinol: influence of dose, duration, and intermittent exposure on indole-3-carbinol promotional potency..
51:2362-2365.
1991
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Rat ovarian granulosa cell culture: a model system for the study of cell-cell communication during multistep transformation..
51:696-706.
1991
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds on the occupied nuclear estrogen receptor in MCF-7 human breast cancer cells..
50:3579-3584.
1990
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Linoleic acid metabolism in metastatic and nonmetastatic murine mammary tumor cells..
49:4724-4728.
1989
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Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor..
49:4531-4535.
1989
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Epidermal growth factor receptor protein-tyrosine kinase activity in human cell lines established from squamous carcinomas of the head and neck..
49:1130-1137.
1989
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Gene for ovarian granulosa cell tumor susceptibility, Gct, in SWXJ recombinant inbred strains of mice revealed by dehydroepiandrosterone..
48:5092-5095.
1988
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Quantitative structure-activity relationships: analysis of interactions of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2-substituted analogues with rat, mouse, guinea pig, and hamster cytosolic receptor..
47:5108-5111.
1987
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Analysis of P210bcr-abl tyrosine protein kinase activity in various subtypes of Philadelphia chromosome-positive cells from chronic myelogenous leukemia patients..
47:1731-1739.
1987
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Quantitative Structure-Activity Relationships: Analysis of Interactions of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and 2-Substituted Analogues with Rat, Mouse, Guinea Pig, and Hamster Cytosolic Receptor1.
47:5092-5140.
1987
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Significance of 1,25-dihydroxyvitamin D3 receptor in primary breast cancers..
46:5406-5408.
1986
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Membrane lipids and enzymes of cultured high- and low-metastatic B16 melanoma variants..
44:3262-3269.
1984
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Video time-lapse microscopy of phagocytosis and intracellular fate of crystalline nickel sulfide particles in cultured mammalian cells..
42:2729-2735.
1982
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Presence of 1,25-dihydroxyvitamin D3 receptors in established human cancer cell lines in culture..
42:1116-1119.
1982
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Frequency of 1,25-dihydroxyvitamin D3 receptor in human breast cancer..
41:5121-5124.
1981
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FREQUENCY OF 1,25-DIHYDROXYVITAMIN-D3 RECEPTOR IN HUMAN-BREAST CANCER.
41:5121-5124.
1981
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Gain-of-Function Chromatin Remodeling Activity of Oncogenic FOXL2-C134W Reprograms Glucocorticoid Receptor Occupancy to Drive Granulosa Cell Tumors.
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In vivo programming of tumor antigen-specific T lymphocytes from pluripotent stem cells to promote cancer immunosurveillance..
71:4742-4747.
-
Proteomic analysis reveals a network of inflammatory genes in epidermis associated with skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice.
71:2729-2729.
-
Activation of NFKB is responsible for defective autophagy in cadmium-induced transformation of prostate cells
2022
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Alternative splicing of the chromatin modifier gene BAZ1A in colorectal cancer.
2022
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Alternative splicing of the chromatin modifier gene BAZ1A in colorectal cancer
2022
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An 18-gene expression model predicts resistance to standard of care therapy on 3-month follow up 18FDG-PET in locally advanced cervical cancer
2022
-
Combinatorial epigenetic targeting of PRC2 complexes upregulates MHC antigen presentation components in melanoma and gastrointestinal cancer cells
2022
-
Combinatorial epigenetic targeting of PRC2 complexes upregulates MHC antigen presentation components in melanoma and gastrointestinal cancer cells.
2022
-
Determining efficacy of combining the MEK inhibitor trametinib with vincristine identified by unbiased high throughput screening in RAS-mutated colorectal cancer cells
2022
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Developing a multifaceted approach to target androgen receptor (AR) in castration resistant prostate cancer
2022
-
Development of novel, non-toxic rifamycins that reverse drug resistance
2022
-
Dietary polyphenols as BRD7 and 9 inhibitors for cancer interception
2022
-
Dietary polyphenols as BRD7 and 9 inhibitors for cancer interception.
2022
-
Discovery of a small molecule inhibitor for triple-negative breast cancer (TNBC)
2022
-
ERBB4 mediates IL10-induced growth of EGFR-independent colon tumors
2022
-
Immunomodulatory activity of sulindac plus erlotinib for colon cancer prevention in familial adenomatous polyposis
2022
-
Immunomodulatory activity of sulindac plus erlotinib for colon cancer prevention in familial adenomatous polyposis.
2022
-
Metabolomics in an Apc-mutant genetic background: Mechanistic insights from acute vs. chronic spinach intake
2022
-
Metabolomics in an Apc-mutant genetic background: Mechanistic insights from acute vs. chronic spinach intake.
2022
-
Molecular landscape of arsenic-induced bladder carcinogenesis
2022
-
Nuclear receptor 4A1 ligands target T-cell exhaustion in colorectal cancer
2022
-
Rb deficient HPV plus HNSCC experienced enhanced sensitivity to aurora kinase inhibitors by altering the balance of MAD2 and TRIP13 levels
2022
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Selective ubiquitination of androgen receptor and its splice variants inhibits castration resistant prostate cancer
2022
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Stochastic modeling uncovers the interplay between early cancer progression and adaptive immune-specific cancer escape
2022
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Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes.
2021
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Aurora kinase inhibitors cause cell death in HPV plus cells: A plausible treatment option for HPV plus cancers.
2021
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Identification of pathways that enhance cell death in NOTCH1-mutant HNSCC.
2021
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Nuclear receptor 4A1 (NR4A1) antagonists target PD-L1 in colon cancer.
2021
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Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells.
2021
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Flavonoids are NR4A1 antagonists and target PAX3-FOXO1 and G9a in alveolar rhabdomyosarcoma cells.
2021
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NR4A1 ligands inhibits PSPC1 regulated EMT and stemness markers in breast, lung and liver cancer cells.
2021
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Determining efficacy of drug combinations identified by unbiased high throughput screening for RAS-mutated colorectal cancer
2020
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Dietary polyphenols as epigenetic 'reader' inhibitors
2020
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High throughput chemical profiling of chemoresistant triple negative breast cancer
2020
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Optimization of dosing regimens of sulindac in combination with erlotinib for small intestine and colorectal cancer prevention
2020
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Out-of-pocket expenditure, probability of underinsurance and health services utilization among non-elderly cancer survivors
2020
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Prospective multi-institutional evaluation of pathologist assessment of PD-L1 assays in triple negative breast cancer
2020
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Promotion of colorectal cancer by Streptococcus gallolyticus-a novel mechanism.
2020
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The involvement of a type VII secretion system in the interactions between Streptococcus gallolyticus subspecies gallolyticus and colorectal cancer.
2020
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Abstract 2171: Activatable nanodelivery of high payload gemcitabine augments therapeutic efficacy in murine breast and pancreatic cancer models
2019
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Abstract 3952: Localized nanodelivery combined with immunotherapy promotes curative anti-tumor responses in a murine breast cancer model
2019
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Optimizing erlotinib plus sulindac dosing regimens in a preclinical model of FAP
2019
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Single cell transcriptomic profiling of ex vivo tumoroid models reveal therapeutic vulnerabilities of pancreatic ductal adenocarcinoma
2019
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Metastatic breast cancer alliance's patient education and access to trials: Perceptions and actions
2019
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A general probabilistic algorithm to predict de novo mutations in familial diseases as demonstrated in Li-Fraumeni Syndrome
2019
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Breast cancer cells exhibit enhanced proliferation, invasion, PLAU expression and chemoresistance when exposed to fluid shear stress in an innovative 3D bioreactor
2018
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Circadian dysregulation via exposure to light at night alters DNA methylation of cancer-associated genes in murine mammary tissue
2018
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Discovery of potent Abelson kinase inhibitors from the scaffold of pyrano[2,3-d]pyrimidin-7-one
2018
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Dysregulated microRNAs in aflatoxin-induced hepatocellular carcinoma: Serum miR-182 as a potential predictive biomarker
2018
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Genomic profiling of canine glioma: Comparative analyses with respect to drivers of human glioma
2018
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Identification of personalized active agents in pediatric medulloblastoma through high-throughput drug screening in matching pairs of patient derived orthotopic xenograft neurosphere and monolayer cells
2018
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Pharmacogenomic screen identifies KMT2D mutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma
2018
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Streptococcus gallolyticus in colorectal cancer development
2018
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Abstract B023: Identification and biochemical validation of piperlongumine as a potent therapeutic against neuroendocrine prostate cancer
2018
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A miRNA signature linked to human environmental risk defined from carcinogen-induced and genetically-driven colon carcinogenesis models
2017
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Abstract 3250: Computational drug repositioning and biochemical validation of piperlongumine as a potent therapeutic agent for neuroendocrine prostate cancer
2017
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Abstract 3772: A multi-scale survey to assess the impact of inflammatory diseases of the abdominal cavity and prostate cancer severity
2017
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Abstract 4603: Protocol optimization combining activatable nanodelivery with immunotherapy in a murine breast cancer model
2017
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Abstract LB-222: A nanoscale optical reporter implant for miRNA biomarkers in vivo
2017
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Dietary amphiphilic polyphenols modulate the biophysical properties of plasma membrane organization and membrane-dependent macropinocytosis
2017
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Identifying genetic modifiers of PTEN using the Collaborative Cross mouse panel
2017
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Plasma membrane lipid therapy: disruption of oncogenic Ras spatiotemporal organization by membrane-targeted dietary bioactives (MTDB)
2017
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Progression of epidermal growth factor receptor (EGFR)-independent colorectal cancer
2017
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Progression of colorectal cancer through epidermal growth factor receptor (EGFR)-independent mechanisms
2017
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Abstract 4448: Elevated levels of circulating miR-34a-5p and miR-181c-3p during cancer initiation by aflatoxin B1
2017
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Genetic dissection of mechanisms underlying epidermal growth factor receptor-independent colorectal cancer development
2016
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Photoacoustic detection and imaging of single cancer cells with peptide conjugated gold nanoparticles
2016
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Abstract 465: CD44 as a potential therapeutic target and prognosis marker for glioblastoma
2016
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Abstract LB-052: Activatable nanodelivery combined with CpG-ODN and anti-PD-1 achieves a complete response in directly-treated and contralateral tumors in a murine breast cancer model
2016
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TWIST1 silences FOXA1 transcription to promote breast cancer progression
2016
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Abstract P5-11-03: Development of an interactive text messaging tool to improve adherence with adjuvant endocrine therapy: Breast cancer endocrine therapy adherence (BETA) pilot study
2016
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Abstract 1083: Temporal trends in microRNAs during subchronic aflatoxin dosing and modulation by the chemopreventive oleane triterpenoid, CDDO-Im
2016
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NF-kappaB-dependent and - independent roles for NIK in regulating GBM cell invasion
2015
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Abstract 3879: Patient preferences for disclosure of incidental genetic information discovered through high-throughput sequencing
2015
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An optimized therapeutic nanoparticle delivery platform of miRNA in preclinical murine models of malignancy
2015
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Antitumor studies: Design, synthesis, antitumor activity and molecular docking study of novel 2-deoxo-2-substituted-5-deazaalloxazines
2015
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PTHrP(12-48) localization is intracellular and it inhibits cell proliferation and osteoclastogenesis
2015
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The influence of masculinity, racism, and social support on colorectal cancer screening uptake among African American men: A systematic review
2015
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Abstract P3-11-02: Predictors of complete pathological response to neoadjuvant chemotherapy for breast cancer: 19,310 cases from the national cancer database treated in 2010 and 2011
2015
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Abstract 695: Synergistic antitumor effects of polo like kinase inhibitor volasertib in combination with ionizing radiation in glioblastoma
2015
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Abstract 1536: Whole genome sequencing of high-grade treatment-nave prostate tumors
2014
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Diagnostic yield of clinical tumor and germline exome sequencing for newly diagnosed children with solid tumors
2014
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Dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner
2014
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Early life exposure to air pollution and promoter methylation in breast tumors in the Western New York Exposures and Breast Cancer Study
2014
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High content clonogenic survival assay for drug library screening identifies potent radiation sensitizers for non-small cell lung cancer
2014
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High-throughput in vitro screening of glioma stem cell lines: Evaluation of over 350 tyrosine kinase inhibitors
2014
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The microRNA profile is altered in fibrosis-associated hepatocarcinogenesis in mice
2014
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CEBPD (C/EBP) acts as a tumor suppressor in hormone receptor positive breast cancer cells and may serve as biomarker to predict the need for adjuvant therapy
2013
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Pharmacokinetic and pharmacodynamic evaluation of novel dual channel spray dried enteric coated self-emulsifying capsules for anti-cancer agents in dogs.
2013
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Abstract 1352: Epithelial-mesenchymal transition (EMT) gene variants influence epithelial ovarian cancer risk in women of European, African and Asian ancestry.
2013
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Abstract 3644: Variation in transmembrane transport genes influence epithelial ovarian cancer risk and histopathologic subtype.
2013
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Abstract 4850: Variation in circadian rhythm genes influence epithelial ovarian cancer risk and invasiveness.
2013
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Abstract A39: Multimodal imaging of blood-brain barrier disruption during brain metastatic progression in a relevant experimental mouse model
2013
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Gallotannins and Gallic acid From Mango Fruit (Mangifera Indica L) Suppress Breast Cancer Tumor Growth by Targeting Phosphatidylinositol3-kinase (PI3K)-Akt-NF-kB Pathway and Associated microRNAs
2012
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Analysis of genome-wide DNA methylation in CCRF-CEM cells confirms hypermethylation at reported epigenetic markers of T-cell lymphoblastic leukemia and identifies novel therapeutic targets with reduced methylation upon treatment with dietary indoles
2012
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Differential effects of sulforaphane and related isothiocyanates on HDAC turnover and the DNA damage response in colon cancer cells
2012
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SRC-3 is a critical mediator in the development of castration-resistant prostate cancer
2012
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Senescence reversion contributes to acquired drug resistance
2012
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Abstract 3592: Risk factors of prostate cancer in African American men
2012
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Proteomic Analysis of Patient Plasma Identifies Parathyroid Hormone Related Protein (PTHrP12-48) as a Potential Biomarker of Breast Cancer Bone Metastasis.
2011
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Defining two populations of prostate cancer cells with distinct molecular, biological, and tumor-propagating properties
2011
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Drug resistance and invasion in diffuse large B-cell lymphoma are mediated by Akt, 14-3-3 zeta, and Vimentin
2011
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Travel distance and pattern of care for laryngeal cancer in Kentucky
2011
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Whole methylome explorations of paired tumor and non-tumor clinical samples using HELP
2011
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Docosahexaenoic acid alters the spatio-temporal segregation and activation of EGF receptor
2010
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Quantitative trait locus analysis of tumor morphology in a mouse model of human colorectal cancer
2010
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n-3 polyunsaturated fatty acids promote apoptosis in oxidatively stressed transgenic mouse models
2010
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Abstract 18: Targeted epidermal ablation of EGFR causes local and systemic inflammation
2010
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Abstract 5538: Enhanced tumor cytotoxicity of a combinational therapy using liposomal copper-doxorubicin, rapamycin, and ultrasound
2010
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Dysregulated eicosanoid signaling associated with COX-2 overexpression in the BK5.COX-2 mouse model of pancreatic cancer
2009
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Histone deacetylase inhibitor induces autophagy through targeting mitochondria
2009
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Bub1 up-regulation and hyper-phosphorylation are major features promoting malignant transformation in SV40 Tag -induced transgenic mouse models
2006
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Growth inhibitory and differentiating effects of anthocyanin-enriched fruit extracts on colon cancer cells
2006
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Characterization of EGFR-independent signaling pathways in ApcMin tumors
2006
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Characterization of proliferative responses of rat lymphatic endothelial cells RMLEC in vitro
2006
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Colonic cyclopurines induced by azoxymethane and irradiation are decreased by dietary fish oil
2006
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Identifying resistance modifiers of azoxymethane induced colon cancer.
2006
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Regulation of Stat3 gene transcription by triplex-forming oliogonucleotides in mice
2006
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TPA-induced expression of the Nmes1 homolog in mouse epidermis is associated with resistance to skin tumor promotion
2006
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Chlorophylls purified by a new large-scale method inhibit aflatoxin carcinogenesis in the rat
2006
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Interactions between white tea and sulindac in the prevention of intestinal cancer
2006
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Natural chlorophyll inhibits dibenzo[a,l]pyrene-induced liver and stomach carcinogenesis in rainbow trout
2006
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Suppression of intestinal tumorigenesis by activator protein 2
2006
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Diverse tumor promoting agents induce epidermal Glutathione S-transferase alpha 4 (Gsta4) levels in tumor promotion resistant C57BL/6 mice
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Gsta4 modifies susceptibility to skin tumor development in mice and humans
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