CANCER RESEARCH
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Overview
publication venue for
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Transient Activation of the Hedgehog-Gli Pathway Rescues Radiotherapy-Induced Dry Mouth via Recovering Salivary Gland Resident Macrophages..
80:5531-5542.
2020
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A Bis-Indole-Derived NR4A1 Antagonist Induces PD-L1 Degradation and Enhances Antitumor Immunity..
80:1011-1023.
2020
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Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition..
79:918-927.
2019
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Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer..
78:4459-4470.
2018
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Long-Chain n-3 Fatty Acids Attenuate Oncogenic KRas-Driven Proliferation by Altering Plasma Membrane Nanoscale Proteolipid Composition..
78:3899-3912.
2018
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PAX3-FOXO1A Expression in Rhabdomyosarcoma Is Driven by the Targetable Nuclear Receptor NR4A1..
77:732-741.
2017
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Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer..
75:5392-5397.
2015
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ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas..
75:1035-1045.
2015
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Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer..
74:5184-5194.
2014
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The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development..
74:38-43.
2014
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Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer..
73:6164-6174.
2013
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Chemopreventive activity of plant flavonoid isorhamnetin in colorectal cancer is mediated by oncogenic Src and β-catenin..
73:5473-5484.
2013
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The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer..
73:3997-4008.
2013
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FGFR1 is essential for prostate cancer progression and metastasis..
73:3716-3724.
2013
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Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer..
72:6490-6501.
2012
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In vivo diagnosis of melanoma and nonmelanoma skin cancer using oblique incidence diffuse reflectance spectrometry..
72:2738-2745.
2012
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Abstract 4007: Different expression ofAHCYL1affecting ovarian carcinogenesis between chickens and women.
72:4007-4007.
2012
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Autophagy enhanced by microtubule- and mitochondrion-associated MAP1S suppresses genome instability and hepatocarcinogenesis..
71:7537-7546.
2011
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In vivo programming of tumor antigen-specific T lymphocytes from pluripotent stem cells to promote cancer immunosurveillance..
71:4742-4747.
2011
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Abstract 1160: Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: Effect of a chemoprotective diet.
71:1160-1160.
2011
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Abstract 2729: Proteomic analysis reveals a network of inflammatory genes in epidermis associated with skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice.
71:2729-2729.
2011
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Activation of Toll-like receptor 5 on breast cancer cells by flagellin suppresses cell proliferation and tumor growth..
71:2466-2475.
2011
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Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk..
71:2098-2107.
2011
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Abstract P4-06-06: Singleminded-2s (Sim2s) Promotes Breast Tumor Cell Differentiation and Inhibits Metastasis in MCF10DCIS.COM Cells.
70:p4-06-06-p4-06-06.
2010
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Heparanase enhances local and systemic osteolysis in multiple myeloma by upregulating the expression and secretion of RANKL..
70:8329-8338.
2010
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Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth..
70:6824-6836.
2010
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Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia..
70:4949-4960.
2010
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Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells..
69:3405-3414.
2009
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Leptin enhances cholangiocarcinoma cell growth..
68:6752-6761.
2008
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Curcumin decreases specificity protein expression in bladder cancer cells..
68:5345-5354.
2008
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Conditional deletion of insulin-like growth factor-I receptor in prostate epithelium..
68:3495-3504.
2008
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Reduced colitis-associated colon cancer in Fat-1 (n-3 fatty acid desaturase) transgenic mice..
68:3985-3991.
2008
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Serotonin Metabolism Is Dysregulated in Cholangiocarcinoma, which Has Implications for Tumor Growth.
68:9184-9193.
2008
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Flat colorectal cancers are genetically determined and progress to invasion without going through a polypoid stage..
67:11594-11600.
2007
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Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway..
67:10782-10788.
2007
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The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells..
67:11001-11011.
2007
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The let-7 microRNA represses cell proliferation pathways in human cells..
67:7713-7722.
2007
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Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial Ca2+ accumulation..
67:5561-5568.
2007
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Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells..
67:3286-3294.
2007
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Betulinic acid inhibits prostate cancer growth through inhibition of specificity protein transcription factors..
67:2816-2823.
2007
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Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway..
67:289-299.
2007
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Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways..
67:674-683.
2007
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Activation of human long interspersed nuclear element 1 retrotransposition by benzo(a)pyrene, an ubiquitous environmental carcinogen..
66:2616-2620.
2006
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3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha..
66:2459-2467.
2006
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Ectopic activity of fibroblast growth factor receptor 1 in hepatocytes accelerates hepatocarcinogenesis by driving proliferation and vascular endothelial growth factor-induced angiogenesis..
66:1481-1490.
2006
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In utero exposure of mice to dibenzo[a,l]pyrene produces lymphoma in the offspring: role of the aryl hydrocarbon receptor..
66:755-762.
2006
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Inhibition of bladder tumor growth by 1,1-bis(3'-indolyl)-1-(p-substitutedphenyl)methanes: a new class of peroxisome proliferator-activated receptor gamma agonists..
66:412-418.
2006
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High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor..
65:11478-11485.
2005
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Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway..
65:11001-11009.
2005
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gamma-Aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway..
65:11437-11446.
2005
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Mechanism of cell cycle regulation by FIP200 in human breast cancer cells..
65:6676-6684.
2005
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Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene..
65:6534-6542.
2005
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Expression of heparanase by primary breast tumors promotes bone resorption in the absence of detectable bone metastases..
65:5778-5784.
2005
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A novel ring-substituted diindolylmethane,1,1-bis[3'-(5-methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia..
65:2890-2898.
2005
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Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis..
65:887-897.
2005
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Erratum: Nuclear factor-B is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma (Cancer Research (September 2004) 64 (6511-6523).
64:8130.
2004
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1,1-Bis(3'-indolyl)-1-(p-substitutedphenyl)methanes induce peroxisome proliferator-activated receptor gamma-mediated growth inhibition, transactivation, and differentiation markers in colon cancer cells..
64:5994-6001.
2004
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Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat..
64:6797-6804.
2004
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Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma..
64:6511-6523.
2004
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Role of Sp proteins in regulation of vascular endothelial growth factor expression and proliferation of pancreatic cancer cells..
64:6740-6749.
2004
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A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase..
64:5767-5774.
2004
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Directionally specific paracrine communication mediated by epithelial FGF9 to stromal FGFR3 in two-compartment premalignant prostate tumors..
64:4555-4562.
2004
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Interaction of the aryl hydrocarbon receptor ligand 6-methyl-1,3,8-trichlorodibenzofuran with estrogen receptor alpha..
64:2889-2897.
2004
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Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators..
64:1050-1057.
2004
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Cooperation between ectopic FGFR1 and depression of FGFR2 in induction of prostatic intraepithelial neoplasia in the mouse prostate..
63:8784-8790.
2003
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Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors..
63:4936-4944.
2003
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Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin..
63:1254-1261.
2003
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Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells..
63:958-964.
2003
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Microarray reveals differences in both tumors and vascular specific gene expression in de novo CD5+ and CD5- diffuse large B-cell lymphomas..
63:60-66.
2003
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Expression of interleukin 8 and not parathyroid hormone-related protein by human breast cancer cells correlates with bone metastasis in vivo..
62:5571-5579.
2002
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Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines..
62:2313-2317.
2002
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Fibroblast growth factor receptor 1 phosphotyrosine 766: molecular target for prevention of progression of prostate tumors to malignancy..
62:1898-1903.
2002
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p53-dependent suppression of uridine phosphorylase gene expression through direct promoter interaction..
61:6899-6905.
2001
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A rare premalignant prostate tumor epithelial cell syndecan-1 forms a fibroblast growth factor-binding complex with progression-promoting ectopic fibroblast growth factor receptor 1..
61:5295-5302.
2001
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Tamoxifen-induced antitumorigenic/antiestrogenic action synergized by a selective aryl hydrocarbon receptor modulator..
61:3902-3907.
2001
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Macrophage arginase promotes tumor cell growth and suppresses nitric oxide-mediated tumor cytotoxicity..
61:1100-1106.
2001
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Signaling events triggered by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): caspase-8 is required for TRAIL-induced apoptosis..
61:1138-1143.
2001
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Modulation of tumor angiogenesis by stem cell factor..
60:6757-6762.
2000
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Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators..
60:4798-4803.
2000
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Genomic structure, chromosomal mapping, and promoter region analysis of murine uridine phosphorylase gene..
59:4997-5001.
1999
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Estrogen receptor activation via activation function 2 predicts agonism of xenoestrogens in normal and neoplastic cells of the uterine myometrium..
59:3090-3099.
1999
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A novel synthetic oleanane triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, with potent differentiating, antiproliferative, and anti-inflammatory activity..
59:336-341.
1999
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High frequency of beta-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat..
58:1127-1129.
1998
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Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells..
57:5369-5378.
1997
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Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid..
57:3424-3428.
1997
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Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras..
57:3180-3188.
1997
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A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice..
57:162-168.
1997
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Inhibition of apoptosis in colon tumors induced in the rat by 2-amino-3-methylimidazo[4,5-f]quinoline..
56:4307-4310.
1996
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Retinoid-induced suppression of squamous cell differentiation in human oral squamous cell carcinoma xenografts (line 1483) in athymic nude mice..
55:3183-3191.
1995
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Dietary fat, fiber, and carcinogen alter fecal diacylglycerol composition and mass..
55:2293-2298.
1995
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Anticarcinogenic activity of indole-3-carbinol acid products: ultrasensitive bioassay by trout embryo microinjection..
54:3617-3619.
1994
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Sequence-specific interaction of a conformational domain of p53 with DNA..
53:5361-5364.
1993
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Characterization of the aryl hydrocarbon receptor and aryl hydrocarbon responsiveness in human ovarian carcinoma cell lines..
53:1802-1807.
1993
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Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1..
51:5304-5307.
1991
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Promotion of aflatoxin B1 carcinogenesis by the natural tumor modulator indole-3-carbinol: influence of dose, duration, and intermittent exposure on indole-3-carbinol promotional potency..
51:2362-2365.
1991
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Rat ovarian granulosa cell culture: a model system for the study of cell-cell communication during multistep transformation..
51:696-706.
1991
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds on the occupied nuclear estrogen receptor in MCF-7 human breast cancer cells..
50:3579-3584.
1990
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Linoleic acid metabolism in metastatic and nonmetastatic murine mammary tumor cells..
49:4724-4728.
1989
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Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterization of the Ah receptor..
49:4531-4535.
1989
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Epidermal growth factor receptor protein-tyrosine kinase activity in human cell lines established from squamous carcinomas of the head and neck..
49:1130-1137.
1989
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Gene for ovarian granulosa cell tumor susceptibility, Gct, in SWXJ recombinant inbred strains of mice revealed by dehydroepiandrosterone..
48:5092-5095.
1988
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Quantitative structure-activity relationships: analysis of interactions of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2-substituted analogues with rat, mouse, guinea pig, and hamster cytosolic receptor..
47:5108-5111.
1987
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Analysis of P210bcr-abl tyrosine protein kinase activity in various subtypes of Philadelphia chromosome-positive cells from chronic myelogenous leukemia patients..
47:1731-1739.
1987
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Quantitative Structure-Activity Relationships: Analysis of Interactions of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and 2-Substituted Analogues with Rat, Mouse, Guinea Pig, and Hamster Cytosolic Receptor1.
47:5092-5140.
1987
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Significance of 1,25-dihydroxyvitamin D3 receptor in primary breast cancers..
46:5406-5408.
1986
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Membrane lipids and enzymes of cultured high- and low-metastatic B16 melanoma variants..
44:3262-3269.
1984
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Video time-lapse microscopy of phagocytosis and intracellular fate of crystalline nickel sulfide particles in cultured mammalian cells..
42:2729-2735.
1982
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Presence of 1,25-dihydroxyvitamin D3 receptors in established human cancer cell lines in culture..
42:1116-1119.
1982
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Frequency of 1,25-dihydroxyvitamin D3 receptor in human breast cancer..
41:5121-5124.
1981
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FREQUENCY OF 1,25-DIHYDROXYVITAMIN-D3 RECEPTOR IN HUMAN-BREAST CANCER.
41:5121-5124.
1981
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Duavee (R) improves metabolic health without increasing cancer risk: findings from a preclinical model of obesity and postmenopausal breast cancer.
2021
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Tet2 Inactivation Enhances the Antitumor Activity of Tumor-Infiltrating Lymphocytes.
2021
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Randomized trial of 12 months of omega-3 fatty acids vs placebo during a weight loss intervention in post-menopausal women at increased risk for breast cancer
2021
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Combined deacetylase and bromodomain inhibition downregulates ERCC2 and suppresses growth of metastatic colon cancer cells.
2021
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Abstract 21: Optimization of dosing regimens of sulindac in combination with erlotinib for small intestine and colorectal cancer prevention
2020
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Abstract 3477: Dietary polyphenols as epigenetic ‘reader' inhibitors
2020
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Abstract 4340: Out-of-pocket expenditure, probability of underinsurance and health services utilization among non-elderly cancer survivors
2020
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Abstract PD5-01: Prospective multi-institutional evaluation of pathologist assessment of PD-L1 assays in triple negative breast cancer
2020
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Abstract 1402: Single cell transcriptomic profiling ofex vivotumoroid models reveal therapeutic vulnerabilities of pancreatic ductal adenocarcinoma
2019
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Abstract 2406: A general probabilistic algorithm to predict de novo mutations in familial diseases as demonstrated in Li-Fraumeni Syndrome
2019
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Abstract 5074: Optimizing erlotinib plus sulindac dosing regimens in a preclinical model of FAP
2019
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Abstract P6-14-03: Metastatic breast cancer alliance's patient education and access to trials: Perceptions and actions
2019
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Abstract 1661: Discovery of potent Abelson kinase inhibitors from the scaffold of pyrano[2,3-d]pyrimidin-7-one
2018
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Abstract 4646: Pharmacogenomic screen identifiesKMT2Dmutations as a biomarker of sensitivity to Aurora kinase inhibition in head and neck and cervical squamous cell carcinoma
2018
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Abstract 5401: Dysregulated microRNAs in aflatoxin-induced hepatocellular carcinoma: Serum miR-182 as a potential predictive biomarker
2018
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Abstract LB-237: Circadian dysregulation via exposure to light at night alters DNA methylation of cancer-associated genes in murine mammary tissue
2018
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Abstract 1542: Identifying genetic modifiers ofPTENusing the Collaborative Cross mouse panel
2017
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Abstract 179: Plasma membrane lipid therapy: disruption of oncogenic Ras spatiotemporal organization by membrane-targeted dietary bioactives (MTDB)
2017
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Abstract 255: Dietary amphiphilic polyphenols modulate the biophysical properties of plasma membrane organization and membrane-dependent macropinocytosis
2017
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Abstract 3400: Progression of epidermal growth factor receptor (EGFR)-independent colorectal cancer
2017
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Abstract A15: Progression of colorectal cancer through epidermal growth factor receptor (EGFR)-independent mechanisms
2017
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Abstract LB-039: Genetic dissection of mechanisms underlying epidermal growth factor receptor-independent colorectal cancer development
2016
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Abstract P2-05-23: TWIST1 silences FOXA1 transcription to promote breast cancer progression
2016
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Abstract B36: NF-kappaB-dependent and -independent roles for NIK in regulating GBM cell invasion
2015
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Abstract 1041: PTHrP(12-48) localization is intracellular and it inhibits cell proliferation and osteoclastogenesis
2015
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Abstract 3742: The influence of masculinity, racism, and social support on colorectal cancer screening uptake among African American men: A systematic review
2015
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Abstract LB-098: Antitumor studies: Design, synthesis, antitumor activity and molecular docking study of novel 2-deoxo-2-substituted-5-deazaalloxazines
2015
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Abstract 4291: An optimized therapeutic nanoparticle delivery platform of miRNA in preclinical murine models of malignancy
2015
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Abstract 265: Early life exposure to air pollution and promoter methylation in breast tumors in the Western New York Exposures and Breast Cancer Study
2014
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Abstract 5169: Diagnostic yield of clinical tumor and germline exome sequencing for newly diagnosed children with solid tumors
2014
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Abstract SY04-02: Dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner
2014
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Abstract 3464: CEBPD (C/EBP) acts as a tumor suppressor in hormone receptor positive breast cancer cells and may serve as biomarker to predict the need for adjuvant therapy.
2013
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Abstract P5-07-03: Gallotannins and Gallic acid From Mango Fruit (Mangifera Indica L) Suppress Breast Cancer Tumor Growth by Targeting Phosphatidylinositol3-kinase (PI3K)-Akt-NF-kB Pathway and Associated microRNAs
2012
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Abstract 3296: SRC-3 is a critical mediator in the development of castration-resistant prostate cancer
2012
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Abstract 5430: Analysis of genome-wide DNA methylation in CCRF-CEM cells confirms hypermethylation at reported epigenetic markers of T-cell lymphoblastic leukemia and identifies novel therapeutic targets with reduced methylation upon treatment with dietary indoles
2012
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Abstract LB-184: Differential effects of sulforaphane and related isothiocyanates on HDAC turnover and the DNA damage response in colon cancer cells
2012
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P4-16-01: Proteomic Analysis of Patient Plasma Identifies Parathyroid Hormone Related Protein (PTHrP12-48) as a Potential Biomarker of Breast Cancer Bone Metastasis.
2011
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Abstract 1928: Travel distance and pattern of care for laryngeal cancer in Kentucky
2011
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Abstract 476: Defining two populations of prostate cancer cells with distinct molecular, biological, and tumor-propagating properties
2011
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Abstract 702: Drug resistance and invasion in diffuse large B-cell lymphoma are mediated by Akt, 14-3-3, and Vimentin
2011
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Abstract 2126: Quantitative trait locus analysis of tumor morphology in a mouse model of human colorectal cancer
2010
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Abstract 276: Docosahexaenoic acid alters the spatio-temporal segregation and activation of EGF receptor
2010
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Abstract 4210: Gsta4 modifies susceptibility to skin tumor development in mice and humans
2010
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Abstract 955: n-3 polyunsaturated fatty acids promote apoptosis in oxidatively stressed transgenic mouse models
2010
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Abstract 72: Metformin enhances tumor regression and reduces tumor burden in a preclinical paradigm modeling obesity's impact on postmenopausal breast cancer
2010
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Dysregulated eicosanoid signaling associated with COX-2 overexpression in the BK5.COX-2 mouse model of pancreatic cancer
2009
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Histone deacetylase inhibitor induces autophagy through targeting mitochondria
2009
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Bub1 up-regulation and hyper-phosphorylation are major features promoting malignant transformation in SV40 Tag -induced transgenic mouse models
2006
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Characterization of EGFR-independent signaling pathways in ApcMin tumors
2006
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Characterization of proliferative responses of rat lymphatic endothelial cells RMLEC in vitro
2006
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Colonic cyclopurines induced by azoxymethane and irradiation are decreased by dietary fish oil
2006
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Diverse tumor promoting agents induce epidermal Glutathione S-transferase alpha 4 (Gsta4) levels in tumor promotion resistant C57BL/6 mice
2006
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Growth inhibitory and differentiating effects of anthocyanin-enriched fruit extracts on colon cancer cells
2006
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Identifying resistance modifiers of azoxymethane induced colon cancer.
2006
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Regulation of Stat3 gene transcription by triplex-forming oliogonucleotides in mice
2006
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Role of IGFBP-3 in the proliferation of MDA-MB-231 breast carcinoma cells in bone metastasis
2006
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TPA-induced expression of the Nmes1 homolog in mouse epidermis is associated with resistance to skin tumor promotion
2006
Identity
International Standard Serial Number (ISSN)