HR job title
- Instructional Assistant Professor
- Contact Info
- 1 979 862 9144
- ORCiD
- 0000-0002-6034-939X
Wu, Chia Shan Research Assistant Professor
Positions
- Research Assistant Professor, Nutrition, College of Agriculture and Life Sciences
- Overview
- Publications
- Research
- Teaching
- Background
- Contact
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Overview
Publications
selected publications
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academic article
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Muthyala, S., Chapkin, R. S., Wu, C., & Wu, C.
(2022).
Ghrelin Alleviates Experimental Ulcerative Colitis in Old Mice and Modulates Colonocyte Metabolism via PPAR Pathway. International Journal of Molecular Sciences.
24(1), 565-565.
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Tuchaai, E., Endres, V., Jones, B., Shankar, S., Klemashevich, C., Sun, Y., & Wu, C.
(2022).
Deletion of ghrelin alters tryptophan metabolism and exacerbates experimental ulcerative colitis in aged mice. Experimental Biology and Medicine.
247(17), 1558-1569.
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Wu, C., & Endres, V.
(2022).
Prior episode of colitis impairs contextual fear memory. Molecular Brain.
15(1), 74.
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Muthyala, S., Shankar, S., Klemashevich, C., Blazier, J. C., Hillhouse, A., & Wu, C.
(2022).
Differential effects of the soluble fiber inulin in reducing adiposity and altering gut microbiome in aging mice. JOURNAL OF NUTRITIONAL BIOCHEMISTRY.
105, 108999-108999.
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Pradhan, G., Lee, J. H., Wu, C., Wang, H., Lin, L., Donti, T., ... Sun, Y.
(2022).
Mechanistic Investigation of GHS-R Mediated Glucose-Stimulated Insulin Secretion in Pancreatic Islets. Biomolecules.
12(3), 407-407.
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Noh, J. Y., Wu, C., DeLuca, J., Devaraj, S., Jayaraman, A., Alaniz, R. C., ... Sun, Y.
(2022).
Novel Role of Ghrelin Receptor in Gut Dysbiosis and Experimental Colitis in Aging. International Journal of Molecular Sciences.
23(4), 2219-2219.
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Perez, J. L., Shivanagoudra, S. R., Perera, W. H., Kim, D. M., Wu, C. S., Sun, Y., Jayaprakasha, G. K., & Patil, B. S.
(2021).
Bitter melon extracts and cucurbitane-type triterpenoid glycosides antagonize lipopolysaccharide-induced inflammation via suppression of NLRP3 inflammasome. Journal of Functional Foods.
86, 104720-104720.
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Wei, Q., Lee, J. H., Wu, C., Zang, Q. S., Guo, S., Lu, H., & Sun, Y.
(2021).
Metabolic and inflammatory functions of cannabinoid receptor type 1 are differentially modulated by adiponectin. World Journal of Diabetes.
12(10), 1750-1764.
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Lee, J. H., Fang, C., Li, X., Wu, C. S., Noh, J. Y., Ye, X., ... Sun, Y.
(2021).
GHS-R suppression in adipose tissues protects against obesity and insulin resistance by regulating adipose angiogenesis and fibrosis. INTERNATIONAL JOURNAL OF OBESITY.
45(7), 1565-1575.
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Pradhan, G., Wu, C., Villarreal, D., Lee, J. H., Han, H. W., Gaharwar, A., ... Sun, Y.
(2021).
Cell GHS-R Regulates Insulin Secretion and Sensitivity. International Journal of Molecular Sciences.
22(8), 3950-3950.
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Wu, C., Muthyala, S., Klemashevich, C., Ufondu, A. U., Menon, R., Chen, Z., ... Sun, Y.
(2021).
Age-dependent remodeling of gut microbiome and host serum metabolome in mice. Aging.
13(5), 6330-6345.
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Wu, C., Wei, Q., Wang, H., Kim, D. M., Balderas, M., Wu, G., ... Sun, Y.
(2020).
Protective Effects of Ghrelin on Fasting-Induced Muscle Atrophy in Aging Mice. Journal of Gerontology Series A: Biological Sciences and Medical Sciences.
75(4), 621-630.
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Wu, C., Jew, C. P., Sun, H., Ballester Rosado, C. J., & Lu, H.
(2020).
mGlu5 in GABAergic neurons modulates spontaneous and psychostimulant-induced locomotor activity. Psychopharmacology.
237(2), 345-361.
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Wu, C., Noh, J., Tuchaai, E., DeLuca, J. A., Allred, K. F., Allred, C. D., & Sun, Y.
(2019).
SUPPRESSION OF GHRELIN SIGNALING EXACERBATES ULCERATIVE COLITIS IN OLDER MICE. Innovation in Aging.
3(Supplement_1), s87-s87.
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Villarreal, D., Pradhan, G., Wu, C., Allred, C. D., Guo, S., & Sun, Y.
(2019).
A Simple High Efficiency Protocol for Pancreatic Islet Isolation from Mice. Journal of Visualized Experiments.
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Villarreal, D., Pradhan, G., Wu, C., Allred, C. D., Guo, S., & Sun, Y.
(2019).
A Simple High Efficiency Protocol for Pancreatic Islet Isolation from Mice. Journal of Visualized Experiments.
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Shivanagoudra, S. R., Perera, W. H., Perez, J. L., Athrey, G., Sun, Y., Wu, C. S., Jayaprakasha, G. K., & Patil, B. S.
(2019).
In vitro and in silico elucidation of antidiabetic and anti-inflammatory activities of bioactive compounds from Momordica charantia L. Bioorganic and Medicinal Chemistry.
27(14), 3097-3109.
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Wu, C., Bongmba, O., Lee, J. H., Tuchaai, E., Zhou, Y. u., Li, D., ... Sun, Y.
(2019).
Ghrelin receptor in agouti-related peptide neurones regulates metabolic adaptation to calorie restriction. Journal of Neuroendocrinology.
31(7), e12763.
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Wu, C., Noh, J. Y., Tuchaai, E., Devaraj, S., Chen, Z., & Sun, Y.
(2019).
Aging gut microbiome profile and ghrelin signaling in microbiome homeostasis. The FASEB Journal.
33(S1), 794.17-794.17.
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Mohankumar, K., Lee, J., Wu, C. S., Sun, Y., & Safe, S.
(2018).
Bis-Indole-Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells. ENDOCRINOLOGY.
159(5), 1950-1963.
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Qiu, X., Guo, H., Yang, J., Ji, Y., Wu, C., & Chen, X.
(2018).
Down-regulation of guanylate binding protein 1 causes mitochondrial dysfunction and cellular senescence in macrophages. Scientific Reports.
8(1), 1679.
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Wei, Q., Lee, J. H., Wang, H., Bongmba, O., Wu, C., Pradhan, G., ... Sun, Y.
(2017).
Adiponectin is required for maintaining normal body temperature in a cold environment. BMC Physiology.
17(1), 8.
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Ma, X., Lin, L., Yue, J., Wu, C., Guo, C. A., Wang, R., ... Sun, Y.
(2017).
Suppression of Ghrelin Exacerbates HFCS-Induced Adiposity and Insulin Resistance. International Journal of Molecular Sciences.
18(6), 1302-1302.
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Pradhan, G., Wu, C., Han Lee, J., Kanikarla, P., Guo, S., Yechoor, V. K., Samson, S. L., & Sun, Y.
(2017).
Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R. Scientific Reports.
7(1), 979.
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Wu, C., Bongmba, O., Yue, J., Lee, J. H., Lin, L., Saito, K., ... Sun, Y.
(2017).
Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis. International Journal of Molecular Sciences.
18(4), 832-832.
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Meadows, A., Lee, J. H., Wu, C., Wei, Q., Pradhan, G., Yafi, M., Lu, H., & Sun, Y.
(2016).
Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity. INTERNATIONAL JOURNAL OF OBESITY.
40(3), 417-424.
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Wu, C., Morgan, D., Jew, C. P., Haskins, C., Andrews, M., Leishman, E., ... Lu, H.
(2014).
Long-term consequences of perinatal fatty acid amino hydrolase inhibition. British Journal of Pharmacology.
171(6), 1420-1434.
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Sun, Y., Pita-Almenar, J. D., Wu, C., Renger, J. J., Uebele, V. N., Lu, H., & Beierlein, M.
(2013).
Biphasic cholinergic synaptic transmission controls action potential activity in thalamic reticular nucleus neurons. Journal of Neuroscience.
33(5), 2048-2059.
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Wu, C., Chen, H., Sun, H., Zhu, J., Jew, C. P., Wager-Miller, J., ... Lu, H.
(2013).
GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination. PLoS ONE.
8(4), e60314-e60314.
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Jew, C. P., Wu, C., Sun, H., Zhu, J., Huang, J., Yu, D., Justice, N. J., & Lu, H.
(2013).
mGluR5 ablation in cortical glutamatergic neurons increases novelty-induced locomotion. PLoS ONE.
8(8), e70415-e70415.
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Daz-Alonso, J., Aguado, T., Wu, C., Palazuelos, J., Hofmann, C., Garcez, P., ... Galve-Roperh, I.
(2012).
The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. Journal of Neuroscience.
32(47), 16651-16665.
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Sun, Y., Wu, C., Renger, J. J., Uebele, V. N., Lu, H., & Beierlein, M.
(2012).
GABAergic synaptic transmission triggers action potentials in thalamic reticular nucleus neurons. Journal of Neuroscience.
32(23), 7782-7790.
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Ljungberg, M. C., Ali, Y. O., Zhu, J., Wu, C., Oka, K., Zhai, R. G., & Lu, H.
(2012).
CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy. Human Molecular Genetics.
21(2), 251-267.
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Wu, C., Lin, J., Chien, C., Chang, W., Lai, H., Chang, C., & Chern, Y.
(2011).
Type VI adenylyl cyclase regulates neurite extension by binding to Snapin and Snap25. Molecular and Cellular Biology.
31(24), 4874-4886.
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Wu, C., Ballester Rosado, C. J., & Lu, H.
(2011).
What can we get from 'barrels': the rodent barrel cortex as a model for studying the establishment of neural circuits. European Journal of Neuroscience.
34(10), 1663-1676.
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Asprer, J., Lee, B., Wu, C., Vadakkan, T., Dickinson, M. E., Lu, H., & Lee, S.
(2011).
LMO4 functions as a co-activator of neurogenin 2 in the developing cortex. Development.
138(13), 2823-2832.
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Wu, C., Jew, C. P., & Lu, H.
(2011).
Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain. Future Neurology.
6(4), 459-480.
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Sun, Y., Wu, C., Lu, H., & Beierlein, M.
(2011).
Target-dependent control of synaptic inhibition by endocannabinoids in the thalamus. Journal of Neuroscience.
31(25), 9222-9230.
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Ballester-Rosado, C. J., Albright, M. J., Wu, C., Liao, C., Zhu, J., Xu, J., Lee, L., & Lu, H.
(2010).
mGluR5 in cortical excitatory neurons exerts both cell-autonomous and -nonautonomous influences on cortical somatosensory circuit formation. Journal of Neuroscience.
30(50), 16896-16909.
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Wu, C., Zhu, J., Wager-Miller, J., Wang, S., O'Leary, D., Monory, K., ... Lu, H.
(2010).
Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. European Journal of Neuroscience.
32(5), 693-706.
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Wu, C., Greenwood, D. R., Cooney, J. M., Jensen, D. J., Tatnell, M. A., Cooper, G., & Mountjoy, K. G.
(2006).
Peripherally administered desacetyl alpha-MSH and alpha-MSH both influence postnatal rat growth and associated rat hypothalamic protein expression. American Journal of Physiology: Endocrinology and Metabolism.
291(6), E1372-E1380.
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Dumont, L. M., Wu, C., Tatnell, M. A., Cornish, J., & Mountjoy, K. G.
(2005).
Evidence for direct actions of melanocortin peptides on bone metabolism. Peptides.
26(10), 1929-1935.
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Daniel, P. B., Fernando, C., Wu, C., Marnane, R., Broadhurst, R., & Mountjoy, K. G.
(2005).
1 kb of 5' flanking sequence from mouse MC4R gene is sufficient for tissue specific expression in a transgenic mouse. Molecular and Cellular Endocrinology.
239(1-2), 63-71.
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Mountjoy, K. G., Jenny Wu, C., Dumont, L. M., & Wild, J. M.
(2003).
Melanocortin-4 receptor messenger ribonucleic acid expression in rat cardiorespiratory, musculoskeletal, and integumentary systems. ENDOCRINOLOGY.
144(12), 5488-5496.
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Mountjoy, K. G., Wu, C., Cornish, J., & Callon, K. E.
(2003).
alpha-MSH and desacetyl-alpha-MSH signaling through melanocortin receptors. Annals of the New York Academy of Sciences.
994(1), 58-65.
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Dumont, L. M., Wu, C. S., Aschkenasi, C. J., Elmquist, J. K., Lowell, B. B., & Mountjoy, K. G.
(2001).
Mouse melanocortin-4 receptor gene 5'-flanking region imparts cell specific expression in vitro. Molecular and Cellular Endocrinology.
184(1-2), 173-185.
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Iqbal, J., Pompolo, S., Dumont, L. M., Wu, C. S., Mountjoy, K. G., Henry, B. A., & Clarke, I. J.
(2001).
Long-term alterations in body weight do not affect the expression of melanocortin receptor-3 and -4 mRNA in the ovine hypothalamus. Neuroscience.
105(4), 931-940.
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Muthyala, S., Chapkin, R. S., Wu, C., & Wu, C.
(2022).
Ghrelin Alleviates Experimental Ulcerative Colitis in Old Mice and Modulates Colonocyte Metabolism via PPAR Pathway. International Journal of Molecular Sciences.
24(1), 565-565.
Research
principal investigator on
- Ghrelin deficiency predisposes mice to aging-associated inflammation through compromised gut function and microbiota dysbiosis awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2019 - 2021
- Ghrelin Signaling Regulates Microbiome-Gut-Brain Axis in Inflammatory Bowel Disease and Post-Traumatic Stress Disorder awarded by Congressionally Directed Medical Research Programs - (Frederick, Maryland, United States) 2018 - 2019
Teaching
teaching activities
- NFSC204 Perspectives Nutr Fstc Instructor
- NFSC485 Directed Studies Instructor
- NFSC491 Hnr- Research Instructor
- NUTR366 Nutrients & Human Body I Instructor
- NUTR469 Exp Nutr Lab Instructor
- NUTR481 Seminar Instructor
- NUTR485 Directed Studies Instructor
- NUTR491 Hnr-research Instructor
- NUTR691 Research Instructor
Background
education and training
- Ph.D. in Physiology, University of Auckland - (Auckland, New Zealand) 2005
- B.T. in Biomedical Sciences, University of Auckland - (Auckland, New Zealand) 1998
Contact
first name
- Chia Shan
has last name
- Wu
mailing address
-
Texas A&M Agrilife Research
Nutrition
2253 TAMUS
College Station, TX 77843-2253
USA
Other
- cjwu@tamu.edu