Research in my laboratory encompasses a range of studies that address the genetics of virulence and pathogenicity. The model systems used in our studies are members of the Burkholderia Cepacia Complex (BCC) composed of nine species. The BCC are recognized as significant pathogens in cystic fibrosis patients. We are currently studying secretion systems responsible for export of a cytotoxic protein(s) in both B. cepacia (plant pathogen) and B. cenocepacia (human pathogen) to determine common mechanisms for pathogenicity. In addition we are conducting genomic analysis of BCC bacteriophage.
Duarte, I., Wang, G., Gill, J. J., Young, R. F., LiPuma, J. J., & Gonzalez, C. F.
(2010).A broad host range tailocin from Burkholderia. Phytopathology: International Journal of the American Phytopathological Society.