HR job title
- Associate Professor
- Contact Info
- 1 979 862 9141
Xie, Linglin Associate Professor
Positions
- Assistant Professor, Nutrition, College of Agriculture and Life Sciences
- Overview
- Publications
- Research
- Teaching
- Background
- Contact
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Overview
Publications
selected publications
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academic article
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He, L., Wang, X., Ding, Z., Liu, L., Cheng, H., Bily, D., ... Xie, L.
(2023).
Deleting Gata4 in hepatocytes promoted the progression of NAFLD via increasing steatosis and apoptosis, and desensitizing insulin signaling. JOURNAL OF NUTRITIONAL BIOCHEMISTRY.
111, 109157-109157.
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Peng, H., Li, J., Xu, H., Wang, X., He, L., McCauley, N., Zhang, K. K., & Xie, L.
(2023).
Offspring NAFLD liver phospholipid profiles are differentially programmed by maternal high-fat diet and maternal one carbon supplement. JOURNAL OF NUTRITIONAL BIOCHEMISTRY.
111, 109187-109187.
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Liu, L., Zhou, Y. i., Liu, Z., Li, J., Hu, L., He, L., ... Xie, L.
(2023).
Osr1 Regulates Macrophage-mediated Liver Inflammation in Nonalcoholic Fatty Liver Disease Progression. CMGH Cellular and Molecular Gastroenterology and Hepatology.
15(5), 1117-1133.
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Lynch, E. C., Liu, Z., Liu, L., Wang, X., Zhang, K. K., & Xie, L.
(2022).
Disrupting Osr1 expression promoted hepatic steatosis and inflammation induced by high-fat diet in the mouse model. PLoS ONE.
17(6), e0268344-e0268344.
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Peng, H., Xu, H., Wu, J., Li, J., Zhou, Y. i., Ding, Z., ... Xie, L.
(2021).
Maternal high-fat diet disrupted one-carbon metabolism in offspring, contributing to nonalcoholic fatty liver disease. Liver International.
41(6), 1305-1319.
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Xie, L.
(2021).
Mog1 to tbx5-cryab/hspb2: A novel signalling network potentiates heart failure?. Acta Physiologica.
231(3), e13593.
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Chen, L., Zhou, T., Wu, N., O'Brien, A., Venter, J., Ceci, L., ... Glaser, S.
(2019).
Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. BBA: Molecular Basis of Disease.
1865(6), 1525-1539.
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Liu, J., Cheng, H., Xiang, M., Zhou, L., Wu, B., Moskowitz, I. P., Zhang, K. e., & Xie, L.
(2019).
Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development. PLOS Genetics.
15(5), e1007711-e1007711.
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Zhou, Y. i., Peng, H., Liu, Z., Zhang, K. K., Jendrusch, C., Drake, M., Hao, Y. i., & Xie, L.
(2019).
Sex-associated preventive effects of low-dose aspirin on obesity and non-alcoholic fatty liver disease in mouse offspring with over-nutrition in utero. Laboratory Investigation.
99(2), 244-259.
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Xu, H., Fu, Q., Zhou, Y. i., Xue, C., Olson, P., Lynch, E. C., ... Xie, L.
(2018).
A long-term maternal diet intervention is necessary to avoid the obesogenic effect of maternal high-fat diet in the offspring. JOURNAL OF NUTRITIONAL BIOCHEMISTRY.
62, 210-220.
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Summerfield, M., Zhou, Y. i., Zhou, T., Wu, C., Alpini, G., Zhang, K. K., & Xie, L.
(2018).
A long-term maternal diet transition from high-fat diet to normal fat diet during pre-pregnancy avoids adipose tissue inflammation in next generation. PLoS ONE.
13(12), e0209053-e0209053.
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Guo, X., Shu, C., Li, H., Pei, Y. a., Woo, S., Zheng, J., ... Wu, C.
(2017).
Cyclic GMP-AMP Ameliorates Diet-induced Metabolic Dysregulation and Regulates Proinflammatory Responses Distinctly from STING Activation. Scientific Reports.
7(1), 6355.
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Zhou, L., Liu, J., Xiang, M., Olson, P., Guzzetta, A., Zhang, K. e., Moskowitz, I. P., & Xie, L.
(2017).
Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation. Proceedings of the National Academy of Sciences of the United States of America.
114(8), E1422-E1431.
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Xie, L., Zhang, K. e., Rasmussen, D., Wang, J., Wu, D., Roemmich, J. N., ... Claycombe, K.
(2017).
Effects of prenatal low protein and postnatal high fat diets on visceral adipose tissue macrophage phenotypes and IL-6 expression in Sprague Dawley rat offspring. PLoS ONE.
12(1), e0169581-e0169581.
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Fu, Q., Olson, P., Rasmussen, D., Keith, B., Williamson, M., Zhang, K. K., & Xie, L.
(2016).
A short-term transition from a high-fat diet to a normal-fat diet before pregnancy exacerbates female mouse offspring obesity. INTERNATIONAL JOURNAL OF OBESITY.
40(4), 564-572.
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Zhang, K. K., Xiang, M., Zhou, L., Liu, J., Curry, N., Heine Suer, D., ... Xie, L.
(2016).
Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation. Human Molecular Genetics.
25(6), 1140-1151.
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Zhou, L., Liu, J., Olson, P., Zhang, K. e., Wynne, J., & Xie, L.
(2015).
Tbx5 and Osr1 interact to regulate posterior second heart field cell cycle progression for cardiac septation. Journal of Molecular and Cellular Cardiology.
85, 1-12.
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Xie, L., Fu, Q., Ortega, T. M., Zhou, L., Rasmussen, D., O'Keefe, J., Zhang, K. K., & Chapes, S. K.
(2014).
Overexpression of IL-10 in C2D macrophages promotes a macrophage phenotypic switch in adipose tissue environments. PLoS ONE.
9(1), e86541-e86541.
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King, B., Jiang, Y. u., Su, X., Xu, J., Xie, L., Standard, J., & Wang, W.
(2013).
Weight control, endocrine hormones and cancer prevention. Experimental Biology and Medicine.
238(5), 502-508.
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Clarke, K., Yang, Y. i., Marsh, R., Xie, L., & Zhang, K. K.
(2013).
Comparative analysis of de novo transcriptome assembly. Science China Life Sciences.
56(2), 156-162.
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Xie, L., & Wang, W.
(2013).
Weight control and cancer preventive mechanisms: role of insulin growth factor-1-mediated signaling pathways. Experimental Biology and Medicine.
238(2), 127-132.
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Xie, L., Hoffmann, A. D., Burnicka-Turek, O., Friedland-Little, J. M., Zhang, K. e., & Moskowitz, I. P.
(2012).
Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. Developmental Cell.
23(2), 280-291.
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Zhang, K. e., Yang, Y. i., Devanarayan, V., Xie, L., Deng, Y., & Donald, S.
(2011).
A hidden Markov model-based algorithm for identifying tumour subtype using array CGH data. BMC GENOMICS.
12 Suppl 5(Suppl 5), S10-S10.
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Xie, L., Weichel, B., Ohm, J. E., & Zhang, K. e.
(2011).
An integrative analysis of DNA methylation and RNA-Seq data for human heart, kidney and liver. BMC Systems Biology.
5 Suppl 3(Suppl 3), S4.
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Ortega, M. T., Xie, L., Mora, S., & Chapes, S. K.
(2011).
Evaluation of macrophage plasticity in brown and white adipose tissue. 271(1), 124-133.
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Xie, L., Ortega, M. T., Mora, S., & Chapes, S. K.
(2010).
Interactive changes between macrophages and adipocytes. Clinical and Vaccine Immunology.
17(4), 651-659.
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Ouyang, P., Jiang, Y. u., Doan, H. M., Xie, L., Vasquez, D., Welti, R., ... Wang, W.
(2010).
Weight Loss via exercise with controlled dietary intake may affect phospholipid profile for cancer prevention in murine skin tissues. Cancer Prevention Research.
3(4), 466-477.
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Xie, L., Jiang, Y., Ouyang, P., Chen, J., Doan, H., Herndon, B., ... Wang, W.
(2008).
Effects of dietary calorie restriction or exercise on the PI3K and Ras signaling pathways in the skin of mice (Journal of Biological Chemistry (2007) 282, (28025-28035)). Journal of Biological Chemistry.
283(23), 16268.
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Lu, J., Xie, L., Sylvester, J., Wang, J., Bai, J., Baybutt, R., & Wang, W.
(2008).
Erratum: Different Gene Expression of Skin Tissues between Mice with Weight Controlled by Either Calorie Restriction or Physical Exercise (Experimental Biology and Medicine (2007) 232 (473-480)). Experimental Biology and Medicine.
233(6), 775.
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Xie, L., O'Reilly, C. P., Chapes, S. K., & Mora, S.
(2008).
Adiponectin and leptin are secreted through distinct trafficking pathways in adipocytes. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.
1782(2), 99-108.
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Xie, L., Jiang, Y. u., Ouyang, P., Chen, J., Doan, H., Herndon, B., ... Wang, W.
(2007).
Effects of dietary calorie restriction or exercise on the PI3K and Ras signaling pathways in the skin of mice. Journal of Biological Chemistry.
282(38), 28025-28035.
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Lu, J., Xie, L., Sylvester, J., Wang, J., Bai, J., Baybutt, R., & Wang, W.
(2007).
Different gene expression of skin tissues between mice with weight controlled by either calorie restriction or physical exercise. Experimental Biology and Medicine.
232(4), 473-480.
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Xie, L., Boyle, D., Sanford, D., Scherer, P. E., Pessin, J. E., & Mora, S.
(2006).
Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles. Journal of Biological Chemistry.
281(11), 7253-7259.
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Xie, L., Gao, Q., & Xu, H.
(2003).
Ameliorative effect of L-methionine on Pb-exposed mice. Biological Trace Element Research.
93(1-3), 227-236.
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Xie, L., Zhu, C., Tian, W., & Gao, Q.
(2003).
[Effect of L-methionine on trace elements in lead-intoxicated mice]. Chinese Journal of Industrial Hygiene and Occupational Diseases.
21(2), 108-110.
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He, L., Wang, X., Ding, Z., Liu, L., Cheng, H., Bily, D., ... Xie, L.
(2023).
Deleting Gata4 in hepatocytes promoted the progression of NAFLD via increasing steatosis and apoptosis, and desensitizing insulin signaling. JOURNAL OF NUTRITIONAL BIOCHEMISTRY.
111, 109157-109157.
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conference paper
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Zhou, T., Kyritsi, K., Wu, N., Francis, H., Yang, Z., Chen, L., ... Glaser, S.
(2019).
Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2-/- mouse model of primary sclerosing cholangitis (PSC). EBioMedicine.
130-142.
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Kaitlin, C., Yi, Y., Ronald, M., Xie, L., & Zhang, K. K.
(2013).
Comparative analysis of de novo transcriptome assembly. 289-295.
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Zhou, T., Kyritsi, K., Wu, N., Francis, H., Yang, Z., Chen, L., ... Glaser, S.
(2019).
Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2-/- mouse model of primary sclerosing cholangitis (PSC). EBioMedicine.
130-142.
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institutional repository document
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Liu, J., Cheng, H., Xiang, M., Zhou, L., Zhang, K. e., Moskowitz, I. P., & Xie, L.
(2018).
Gata4 drives Hh-signaling for second heart field migration and outflow tract development
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Liu, J., Cheng, H., Xiang, M., Zhou, L., Zhang, K. e., Moskowitz, I. P., & Xie, L.
(2018).
Gata4 drives Hh-signaling for second heart field migration and outflow tract development
Research
principal investigator on
- A poly-omic study of the molecular mechanisms underlying maternal diet interventions for offspring obesity and NAFLD awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2017 - 2022
- A study of maternal Diet interventions on offspring obesity and non-alcoholic fatty liver disease. awarded by National Institute of Food and Agriculture - (Washington D.C., District of Columbia, United States) 2016 - 2021
- An Important Role of Osr1 in Outflow Tract Development awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2017 - 2019
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- GENE491 Hnr-research Instructor
- NFSC301 Nutr Through Life Instructor
- NFSC485 Directed Studies Instructor
- NFSC491 Reseach Instructor
- NFSC681 Seminar Instructor
- NFSC685 Directed Studies Instructor
- NFSC691 Research Instructor
- NUTR301 Nutr Through Life Instructor
- NUTR481 Seminar Instructor
- NUTR485 Directed Studies Instructor
- NUTR491 Hnr-research Instructor
- NUTR681 Seminar Instructor
- NUTR685 Directed Studies Instructor
- NUTR689 Sptp: Gene Epig Int Diet Instructor
- NUTR691 Research Instructor
Background
education and training
- Ph.D. in Biology, Kansas State University - (Manhattan, Kansas, United States) 2008
Contact
first name
- Linglin
has last name
- Xie
mailing address
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Texas A&M University
Nutrition & Food Science
2253 TAMU
College Station, TX 77843-2253
USA
Other
- linglin.xie@tamu.edu