TOXICOLOGY AND APPLIED PHARMACOLOGY
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Overview
publication venue for
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Lactational transfer of sulforaphane-N-acetylcysteine in vivo and in human breast milk..
482:116796-116796.
2023
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Exposure of environmental trace elements in prostate cancer patients: A multiple metal analysis..
479:116728-116728.
2023
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Decanoic acid suppresses proliferation and invasiveness of human trophoblast cells by disrupting mitochondrial function..
339:121-132.
2018
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Effects of pirfenidone in acute and sub-chronic liver fibrosis, and an initiation-promotion cancer model in the mouse..
339:1-9.
2018
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Inactivation of the orphan nuclear receptor NR4A1 contributes to apoptosis induction by fangchinoline in pancreatic cancer cells..
332:32-39.
2017
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In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model..
322:60-74.
2017
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The role of microRNAs in the development and progression of chemical-associated cancers..
312:3-10.
2016
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A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways..
310:129-139.
2016
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2,3,7,8-Tetrachlorodibenzo-p-dioxin has both pro-carcinogenic and anti-carcinogenic effects on neuroendocrine prostate carcinoma formation in TRAMP mice..
305:242-249.
2016
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Development and application of a rat PBPK model to elucidate kidney and liver effects induced by ETBE and tert-butanol..
288:439-452.
2015
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Prediction of binding affinity and efficacy of thyroid hormone receptor ligands using QSAR and structure-based modeling methods..
280:177-189.
2014
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Aspirin-triggered resolvin D1 down-regulates inflammatory responses and protects against endotoxin-induced acute kidney injury..
277:118-123.
2014
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Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity..
273:500-507.
2013
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Identification of putative estrogen receptor-mediated endocrine disrupting chemicals using QSAR- and structure-based virtual screening approaches..
272:67-76.
2013
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Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: maternal diets rich in indole-3-carbinol versus sulforaphane..
270:60-69.
2013
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Acetaminophen-induced acute liver injury in HCV transgenic mice..
266:224-232.
2013
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3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells..
263:345-351.
2012
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Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet..
262:52-59.
2012
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Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity..
249:208-216.
2010
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ATP7B detoxifies silver in ciliated airway epithelial cells..
243:315-322.
2010
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Role of retinoic acid in the modulation of benzo(a)pyrene-DNA adducts in human hepatoma cells: Implications for cancer prevention.
249:224-230.
2010
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Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine..
238:90-99.
2009
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Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liver..
235:199-207.
2009
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Disruption of period gene expression alters the inductive effects of dioxin on the AhR signaling pathway in the mouse liver..
234:370-377.
2009
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Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease..
232:236-243.
2008
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Ligand-dependent interactions of the Ah receptor with coactivators in a mammalian two-hybrid assay..
227:196-206.
2008
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Time course investigation of PPARalpha- and Kupffer cell-dependent effects of WY-14,643 in mouse liver using microarray gene expression..
225:267-277.
2007
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Cobaltous chloride and hypoxia inhibit aryl hydrocarbon receptor-mediated responses in breast cancer cells..
223:28-38.
2007
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Comparative non-cholinergic neurotoxic effects of paraoxon and diisopropyl fluorophosphate (DFP) on human neuroblastoma and astrocytoma cell lines..
219:162-171.
2007
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Isolation and characterization of two disintegrins inhibiting ADP-induced human platelet aggregation from the venom of Crotalus scutulatus scutulatus (Mohave Rattlesnake)..
212:59-68.
2006
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Physiological role of mGSTA4-4, a glutathione S-transferase metabolizing 4-hydroxynonenal: generation and analysis of mGsta4 null mouse..
194:296-308.
2004
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The hidden effect of estrogenic/antiandrogenic methoxychlor on spermatogenesis..
180:129-135.
2002
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Cytotoxicity and aromatase (CYP19) activity modulation by organochlorines in human placental JEG-3 and JAR choriocarcinoma cells..
160:10-20.
1999
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Chlorophyllin chemoprevention in trout initiated by aflatoxin B(1) bath treatment: An evaluation of reduced bioavailability vs. target organ protective mechanisms..
158:141-151.
1999
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Halogenated aromatic hydrocarbons suppress CA1 field excitatory postsynaptic potentials in rat hippocampal slices..
148:7-13.
1998
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Additive estrogenic activities of a binary mixture of 2',4',6'-trichloro- and 2',3',4',5'-tetrachloro-4-biphenylol..
147:93-100.
1997
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Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships..
145:111-123.
1997
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Antiestrogenic activity of hydroxylated polychlorinated biphenyl congeners identified in human serum..
142:160-168.
1997
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Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring..
141:68-75.
1996
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on insulin-induced responses in MCF-7 human breast cancer cells..
138:242-250.
1996
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Eptastigmine-phosphotriesterase combination in DFP intoxication..
140:364-369.
1996
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Phosphotriesterase, pralidoxime-2-chloride (2-PAM) and eptastigmine treatments and their combinations in DFP intoxication..
141:555-560.
1996
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Alkyl polychlorinated dibenzofurans and related compounds as antiestrogens in the female rat uterus: structure-activity studies..
135:287-298.
1995
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Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin and retinoic acid in MCF-7 human breast cancer cells..
127:1-8.
1994
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Encapsulation of phosphotriesterase within murine erythrocytes..
124:296-301.
1994
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Mechanism of action of alpha-naphthoflavone as an Ah receptor antagonist in MCF-7 human breast cancer cells..
120:179-185.
1993
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Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) as antiestrogens in MCF-7 human breast cancer cells: quantitative structure-activity relationships..
120:55-61.
1993
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Phosphotriesterase decreases paraoxon toxicity in mice..
121:275-278.
1993
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6-Methyl-1,3,8-trichlorodibenzofuran (MCDF) as an antiestrogen in human and rodent cancer cell lines: evidence for the role of the Ah receptor..
113:311-318.
1992
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The effect of 6-nitro-1,3,8-trichlorodibenzofuran as a partial estrogen in the female rat uterus..
113:55-63.
1992
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Reply.
108:568-569.
1991
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Evaluation of the developmental toxicity of chlorinated phenols utilizing Hydra attenuata and postimplantation rat embryos in culture..
108:253-266.
1991
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Immunosuppressive and monooxygenase induction activities of polychlorinated diphenyl ether congeners in C57BL/6N mice: quantitative structure-activity relationships..
105:254-263.
1990
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Structure-dependent induction of aryl hydrocarbon hydroxylase activity in C57BL/6 mice by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related congeners: mechanistic studies..
105:243-253.
1990
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on I-compounds in hepatic DNA of Sprague-Dawley rats: sex-specific effects and structure-activity relationships..
103:271-280.
1990
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2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced porphyria in genetically inbred mice: partial antagonism and mechanistic studies..
100:208-216.
1989
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2,2',4,4',5,5'-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice..
97:561-571.
1989
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Modulation of diethylnitrosamine-induced hepatocarcinogenesis and O6-ethylguanine formation in rainbow trout by indole-3-carbinol, beta-naphthoflavone, and Aroclor 1254..
96:93-100.
1988
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Comparative antiestrogenic activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 6-methyl-1,3,8-trichlorodibenzofuran in the female rat..
95:435-443.
1988
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Allylamine-induced vascular toxicity in vitro: prevention by semicarbazide-sensitive amine oxidase inhibitors..
95:61-71.
1988
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Immunosuppressive activities of polychlorinated dibenzofuran congeners: quantitative structure-activity relationships and interactive effects..
94:141-149.
1988
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Comparative activities of 2,3,7,8-tetrachlorodibenzo-p-dioxin and progesterone as antiestrogens in the female rat uterus..
92:368-380.
1988
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Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic and uterine estrogen receptor levels in rats..
87:306-314.
1987
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Monoclonal antibodies to chlorinated dibenzo-p-dioxins..
82:256-263.
1986
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Comparative influences of different PB-type and 3-MC-type polychlorinated biphenyl-induced phenotypes on cytocidal hepatotoxicity of bromobenzene and acetaminophen..
76:118-127.
1984
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2-hexanone potentiation of [14C]chloroform hepatotoxicity: covalent interaction of a reactive intermediate with rat liver phospholipid..
73:478-491.
1984
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Cytotoxicity of isoproterenol to cultured heart cells: effects of antioxidants on modifying membrane damage..
70:317-323.
1983
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The comparative biologic and toxic potencies of polychlorinated biphenyls and polybrominated biphenyls..
70:204-215.
1983
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The role of lysosomes in the pathogenesis of copper-induced hepatotoxicity. II. Intracellular distribution of copper in hepatocytes..
67:238-245.
1983
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Induction of drug-metabolizing enzymes by fractionated commercial polybrominated biphenyls (PBBs)..
57:254-262.
1981
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Effect of penicillic acid on adenosine triphosphatase activity in the mouse..
49:365-372.
1979
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Isomerically pure bromobiphenyl congeners and hepatic mono-oxygenase activities in the rat: influence of position and degree of bromination..
47:341-352.
1979
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COMPARATIVE METABOLISM OF HALOGENATED BIPHENYLS.
48:A181-A181.
1979
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In vitro and in vivo effects of penicillic acid on adenosine triphosphatase activities in mouse.
48.
1979
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Inhibitory characteristics of the mycotoxin penicillic acid on (Na+-K+)-activated adenosine triphosphatase.
48.
1979
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The comparative metabolism of halogenated biphenyls.
48.
1979
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Acute toxicity of patulin.
45.
1978
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Halogen substituents at the 4- and 4'-positions of biphenyl: influence on hepatic function in the rat..
42:359-366.
1977
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Effects of patulin on adenosine triphosphatase activities in the mouse..
42:175-187.
1977
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Effects of chronic lead treatment on some cardiovascular responses to norepinephrine in the rat..
40:407-413.
1977
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HALOGEN SUBSTITUENTS AT 4-POSITION AND 4'-POSITION OF BIPHENYL - INFLUENCE ON HEPATIC FUNCTION IN RAT.
41:220-220.
1977
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A fetal whole ovarian culture model for the evaluation of CrVI-induced developmental toxicity during germ cell nest breakdown..
289:58-69.
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An approach for integrating toxicogenomic data in risk assessment: the dibutyl phthalate case study..
271:324-335.
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An in vitro-in silico workflow for predicting renal clearance of PFAS..
489:117015-117015.
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Approaches to advancing quantitative human health risk assessment of environmental chemicals in the post-genomic era..
271:309-323.
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Attenuation of gossypol cytotoxicity by cyclic AMP in a rat liver cell line..
151:311-318.
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Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver and kidney slices..
152:302-308.
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Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach..
241:36-60.
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Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice..
228:315-325.
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Comparative toxicity of eugenol and its quinone methide metabolite in cultured liver cells using kinetic fluorescence bioassays..
149:55-63.
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Development and evaluation of a harmonized physiologically based pharmacokinetic (PBPK) model for perchloroethylene toxicokinetics in mice, rats, and humans..
253:203-234.
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Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in TCE-induced hepatomegaly..
236:329-340.
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Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53..
251:253-266.
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Incorporation of the glutathione conjugation pathway in an updated physiologically-based pharmacokinetic model for perchloroethylene in mice..
352:142-152.
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Induction of endoplasmic reticulum stress might be responsible for defective autophagy in cadmium-induced prostate carcinogenesis..
373:62-68.
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Lactational exposure to hexavalent chromium delays puberty by impairing ovarian development, steroidogenesis and pituitary hormone synthesis in developing Wistar rats..
232:180-189.
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Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line..
253:45-56.
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NOX4 mediates cytoprotective autophagy induced by the EGFR inhibitor erlotinib in head and neck cancer cells..
272:736-745.
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Neurotoxicity induced in differentiated SK-N-SH-SY5Y human neuroblastoma cells by organophosphorus compounds..
186:110-118.
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PBPK modeling of impact of nonalcoholic fatty liver disease on toxicokinetics of perchloroethylene in mice..
400:115069-115069.
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Patulin-induced cellular toxicity: a vital fluorescence study..
112:235-244.
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Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes..
381:114711-114711.
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Profiling of differentially expressed genes in cadmium-induced prostate carcinogenesis..
375:57-63.
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Resveratrol protects the ovary against chromium-toxicity by enhancing endogenous antioxidant enzymes and inhibiting metabolic clearance of estradiol..
303:65-78.
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Sulfur mustard induces an endoplasmic reticulum stress response in the mouse ear vesicant model..
268:178-187.
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Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment..
271:299-308.
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Detoxification of organophosphate nerve agents by bacterial phosphotriesterase.
2005
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Engineered variants of phosphotriesterase for enhanced detoxification of organophosphate nerve agents
2004
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