selected publications academic article Prutsch, N., Vromman, A., Leeper, B., Chen, M., He, S., Ren, S., ... Look, A. T. (2023). Mechanisms and Therapeutic Strategies to Reverse TET2 Mutant Clonal Hematopoiesis and the Risk of MDS, AML, and Atherosclerotic Cardiovascular Disease. Blood. 142(Supplement 1), 937-937. Pagan, L. U., Gomes, M. J., Damatto, F. C., Oliveira, J., Gatto, M., Souza, L. M., ... Okoshi, K. (2023). Effects of SGLT2 inhibition on cardiac remodeling and heart failure development in rats with aortic stenosis. European Heart Journal. 44(Supplement_2), ehad655.1661. Rodrigues, E. A., Lima, A., Gomes, M. J., Souza, L. M., Pontes, T., Pagan, L. U., ... Okoshi, M. P. (2023). Influence of Isolated Resistance Exercise on Cardiac Remodeling, Myocardial Oxidative Stress, and Metabolism in Infarcted Rats. Antioxidants. 12(4), 896-896. Souza, L. M., Gomes, M. J., Brandao, B. B., Pagan, L. U., Gatto, M., Damatto, F. C., ... Okoshi, M. P. (2023). Effects of Resistance Exercise on Slow-Twitch Soleus Muscle of Infarcted Rats. Antioxidants. 12(2), 291-291. Janini Gomes, M., Sabela, A. K., Ferreira, I., de Souza, S., Mota, G., da Silva, V. L., ... Pacagnelli, F. L. (2023). Effects of aerobic exercise on cardiac function and gene expression of NADPH oxidases in diaphragm muscle of rats with aortic stenosis-induced heart failure. Frontiers in Physiology. 14, 1182303. Rodrigues, E., Souza, L. M., Pontes, T., Gomes, M. J., Pagan, L. U., Murata, G. M., ... Okoshi, M. P. (2022). Effects of resistance exercise in the cardiac remodeling of myocardial infarction rats. European Heart Journal. 43(Supplement_2), Damatto, F. C., Paschoareli, G. L., Rosa, C. M., Gomes, M. J., Pagan, L. U., Damatto, R. L., ... Okoshi, K. (2022). Influence of the SGLT2 inhibitor empagliflozin on post myocardial infarction rat hearts. European Heart Journal. 43(Supplement_2), Rosa, C. M., Campos, D., Reyes, D., Damatto, F. C., Kurosaki, L. Y., Pagan, L. U., ... Okoshi, K. (2022). Effects of the SGLT2 Inhibition on Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats, a Model of Type 1 Diabetes Mellitus. Antioxidants. 11(5), 982-982. Pagan, L. U., Gomes, M. J., Martinez, P. F., & Okoshi, M. P. (2022). Oxidative Stress and Heart Failure: Mechanisms, Signalling Pathways, and Therapeutics. Oxidative Medicine and Cellular Longevity. 2022, 9829505-3. Pagan, L. U., Gomes, M. J., Gatto, M., Mota, G., Okoshi, K., & Okoshi, M. P. (2022). The Role of Oxidative Stress in the Aging Heart. Antioxidants. 11(2), 336-336. Gatto, M., Mota, G., Pagan, L. U., Gomes, M. J., & Okoshi, M. P. (2021). Preconditioning in Ischemia-Reperfusion Lesion. Arquivos Brasileiros de Cardiologia. 117(6), 1145-1146. Souza, L. M., Gomes, M. J., Pagan, L. U., Rodrigues, E. A., Pontes, T., Fernandes, A., ... Okoshi, M. P. (2021). Influence of resistance exercise on cardiac remodeling and soleus muscle of infarcted rats. European Heart Journal. 42(Supplement_1), ehab724.2677. Souza, L. M., Okoshi, M. P., Gomes, M. J., Gatto, M., Rodrigues, E. A., Pontes, T., ... Pagan, L. U. (2021). Effects of Late Aerobic Exercise on Cardiac Remodeling of Rats with Small-Sized Myocardial Infarction. Arquivos Brasileiros de Cardiologia. 116(4), 784-792. Lawler, J. M., Hord, J. M., Ryan, P., Holly, D., Janini Gomes, M., Rodriguez, D., ... Kamal, K. Y. (2021). Nox2 Inhibition Regulates Stress Response and Mitigates Skeletal Muscle Fiber Atrophy during Simulated Microgravity. International Journal of Molecular Sciences. 22(6), 3252-3252. Pagan, L. U., Gomes, M. J., Damatto, R. L., Lima, A., Cezar, M., Damatto, F. C., ... Okoshi, K. (2021). Aerobic Exercise During Advance Stage of Uncontrolled Arterial Hypertension. Frontiers in Physiology. 12, 675778. Gomes, M. J., & Pagan, L. U. (2020). Heart Rate Control in Heart Failure. Arquivos Brasileiros de Cardiologia. 115(6), 1070-1071. Souza, L. M., Okoshi, M. P., Gomes, M. J., Rodrigues, E. A., Pontes, T., Damatto, F. C., ... Pagan, L. U. (2020). Effects of late aerobic exercise on cardiac remodeling of rats with small myocardial infarction. European Heart Journal. 41(Supplement_2), Pagan, L. U., Gomes, M. J., & Okoshi, M. P. (2020). Overview of Recent Advances in Experimental Cardiovascular Research. Arquivos Brasileiros de Cardiologia. 115(4), 593-594. Pacagnelli, F. L., Aguiar, A. F., Engel, L. E., Bongiovani, A. C., & Gomes, M. J. (2020). Intermittent Diet in Exercise-Induced Cardiac Remodeling. Arquivos Brasileiros de Cardiologia. 115(2), 194-196. Gomes, M. J., Pagan, L. U., Lima, A., Reyes, D., Martinez, P. F., Damatto, F. C., ... Okoshi, M. P. (2020). Effects of aerobic and resistance exercise on cardiac remodelling and skeletal muscle oxidative stress of infarcted rats. Journal of Cellular and Molecular Medicine. 24(9), 5352-5362. Pagan, L. U., Damatto, R. L., Gomes, M. J., Lima, A., Cezar, M., Damatto, F. C., ... Okoshi, K. (2019). Low-intensity aerobic exercise improves cardiac remodelling of adult spontaneously hypertensive rats. Journal of Cellular and Molecular Medicine. 23(9), 6504-6507. Gomes, M. J., Pagan, L. U., & Okoshi, M. P. (2019). Non-Pharmacological Treatment of Cardiovascular Disease | Importance of Physical Exercise. Arquivos Brasileiros de Cardiologia. 113(1), 9-10. Cezar, M., Pagan, L. U., Damatto, R. L., Lima, A., & Gomes, M. J. (2019). Cardioprotective Effects of Resistance Training on Obesity. Arquivos Brasileiros de Cardiologia. 112(5), 553-554. Lawler, J. M., Garcia-Villatoro, E. L., Guzzoni, V., Hord, J. M., Botchlett, R., Holly, D., ... Talcott, S. (2019). Effect of combined fish oil & Curcumin on murine skeletal muscle morphology and stress response proteins during mechanical unloading. NUTRITION RESEARCH. 65, 17-28. Reyes, D., Gomes, M. J., Rosa, C. M., Pagan, L. U., Zanati, S. G., Damatto, R. L., ... Okoshi, M. P. (2019). Exercise during transition from compensated left ventricular hypertrophy to heart failure in aortic stenosis rats. Journal of Cellular and Molecular Medicine. 23(2), 1235-1245. Cezar, M., Gomes, M. J., & Damatto, R. L. (2019). Prenatal Stress: Molecular Mechanisms and Cardiovascular Disease. Arquivos Brasileiros de Cardiologia. 112(1), 76-77. Pagan, L. U., Gomes, M. J., & Okoshi, M. P. (2018). Endothelial Function and Physical Exercise. Arquivos Brasileiros de Cardiologia. 111(4), 540-541. Kuczmarski, J. M., Hord, J. M., Lee, Y., Guzzoni, V., Rodriguez, D., Lawler, M. S., ... Lawler, J. M. (2018). Effect of Eukarion-134 on Akt-mTOR signalling in the rat soleus during 7days of mechanical unloading. 103(4), 545-558. Lima, A., Pagan, L. U., Damatto, R. L., Cezar, M., Bonomo, C., Gomes, M. J., ... Okoshi, M. P. (2017). Effects of growth hormone on cardiac remodeling and soleus muscle in rats with aortic stenosis-induced heart failure. Oncotarget. 8(47), 83009-83021. Gomes, M. J., Martinez, P. F., Pagan, L. U., Damatto, R. L., Cezar, M., Lima, A., Okoshi, K., & Okoshi, M. P. (2017). Skeletal muscle aging: influence of oxidative stress and physical exercise. Oncotarget. 8(12), 20428-20440. Reyes, D., Gomes, M. J., Rosa, C. M., Pagan, L. U., Damatto, F. C., Damatto, R. L., ... Okoshi, M. P. (2017). N-Acetylcysteine Influence on Oxidative Stress and Cardiac Remodeling in Rats During Transition from Compensated Left Ventricular Hypertrophy to Heart Failure. Cellular Physiology and Biochemistry. 44(6), 2310-2321. Guizoni, D. M., Oliveira-Junior, S. A., Noor, S., Pagan, L. U., Martinez, P. F., Lima, A., ... Okoshi, M. P. (2016). Effects of late exercise on cardiac remodeling and myocardial calcium handling proteins in rats with moderate and large size myocardial infarction. International Journal of Cardiology. 221, 406-412. Gomes, M. J., Martinez, P. F., Campos, D., Pagan, L. U., Bonomo, C., Lima, A., ... Okoshi, M. P. (2016). Beneficial Effects of Physical Exercise on Functional Capacity and Skeletal Muscle Oxidative Stress in Rats with Aortic Stenosis-Induced Heart Failure. Oxidative Medicine and Cellular Longevity. 2016, 8695716-12. Cezar, M., Damatto, R. L., Pagan, L. U., Lima, A., Martinez, P. F., Bonomo, C., ... Okoshi, K. (2015). Early Spironolactone Treatment Attenuates Heart Failure Development by Improving Myocardial Function and Reducing Fibrosis in Spontaneously Hypertensive Rats. Cellular Physiology and Biochemistry. 36(4), 1453-1466. Pagan, L. U., Damatto, R. L., Cezar, M., Lima, A., Bonomo, C., Campos, D., ... Okoshi, K. (2015). Long-term low intensity physical exercise attenuates heart failure development in aging spontaneously hypertensive rats. Cellular Physiology and Biochemistry. 36(1), 61-74.
teaching activities KINE433 Physiology Of Exercise Instructor KINE491 Research Instructor KINE684 Prof Internship Instructor KINE685 Directed Studies Instructor
education and training Ph.D. in Internal Medicine, Sao Paulo State University - (São Paulo, Brazil) 2019