Genes expressed in neurons of adult male Drosophila. Academic Article uri icon


  • We have identified two genes, roX1 and roX2, whose expression in the adult fly is restricted to neurons of males. The two genes reside on the X chromosome, and each encodes an RNA with no apparent open reading frame. Both genes are physically linked to female-specific genes that encode proteins expressed in the ovary: opt1, a novel peptide transporter, and nod, a member of the kinesin family. The male-specific transcripts are positively regulated by the dosage compensation pathway in an all-or-none fashion. Our data suggest that the multimeric complex of dosage compensation proteins may operate in different ways on different sets of X-linked genes.

published proceedings

  • Cell

altmetric score

  • 9

author list (cited authors)

  • Amrein, H., & Axel, R.

citation count

  • 192

complete list of authors

  • Amrein, H||Axel, R

publication date

  • February 1997

published in