HR job title
- Professor
- Contact Info
- 1 979 845 1797
Ko, Gladys Professor
Positions
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Overview
Publications
selected publications
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academic article
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Pham, D., Niemi, A., Blank, R., & Ko, G.
(2022).
Abstract 11032: Peptide Lv Promotes the Trafficking and Membrane Insertion of Endothelial KCa31 Through the MEK1/ERK Pathway. Circulation.
146(Suppl_1), a11032-a11032.
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Ko, G., Yu, F., Bayless, K. J., & Ko, M. L.
(2022).
MicroRNA-150 (miR-150) and Diabetic Retinopathy: Is miR-150 Only a Biomarker or Does It Contribute to Disease Progression?. 23(20), 12099-12099.
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McCauley, N., Lawless, L., Basra, M., DePadova, N., Loyola, X. A., Zhou, H., ... Xie, L.
(2022).
In ovo exposure to cadmium causes right ventricle hyperplasia due to cell proliferation of cardiomyocytes. Toxicology Letters.
366, 1-6.
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Uppada, S., Zou, D., Scott, E. M., Ko, G., Pflugfelder, S., Kumar, M., & Ganugula, R.
(2022).
Paclitaxel and Urolithin A Prevent Histamine-Induced Neurovascular Breakdown Alike, in an Ex Vivo Rat Eye Model. ACS Chemical Neuroscience.
13(14), 2092-2098.
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Pham, D. L., Niemi, A., Ko, M. L., & Ko, G.
(2022).
Peptide Lv augments intermediate-conductance calcium-dependent potassium channels (KCa3.1) in endothelial cells to promote angiogenesis. PLoS ONE.
17(10), e0276744-e0276744.
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Yu, F., Ko, M. L., & Ko, G.
(2021).
MicroRNA-150 and its target ETS-domain transcription factor 1 contribute to inflammation in diabetic photoreceptors. Journal of Cellular and Molecular Medicine.
25(22), 10724-10735.
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Yu, F., Ko, M. L., & Ko, G.
(2021).
Decreased MicroRNA-150 Exacerbates Neuronal Apoptosis in the Diabetic Retina. Biomedicines.
9(9), 1135-1135.
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Ding, Z., Zhou, H., McCauley, N., Ko, G., Zhang, K. K., & Xie, L.
(2020).
In ovo hyperglycemia causes congenital limb defects in chicken embryos via disruption of cell proliferation and apoptosis. BBA: Molecular Basis of Disease.
1866(12), 165955-165955.
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Yu, F., Chapman, S., Pham, D. L., Ko, M. L., Zhou, B., & Ko, G.
(2020).
Decreased miR-150 in obesity-associated type 2 diabetic mice increases intraocular inflammation and exacerbates retinal dysfunction. BMJ Open Diabetes Research and Care.
8(1), e001446-e001446.
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Ko, G.
(2020).
Circadian regulation in the retina: From molecules to network. European Journal of Neuroscience.
51(1), 194-216.
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Raghunathan, S., Islas, J. F., Mistretta, B., Iyer, D., Shi, L., Gunaratne, P. H., ... McConnell, B. K.
(2020).
Conversion of human cardiac progenitor cells into cardiac pacemaker-like cells. Journal of Molecular and Cellular Cardiology.
138, 12-22.
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Shi, L., Zhao, M., Abbey, C. A., Tsai, S., Xie, W., Pham, D., ... Ko, G.
(2019).
Newly Identified Peptide, Peptide Lv, Promotes Pathological Angiogenesis. Journal of the American Heart Association.
8(22), e013673.
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Chang, J., Yu, F., Shi, L., Ko, M. L., & Ko, G.
(2019).
Melatonin Affects Mitochondrial Fission/Fusion Dynamics in the Diabetic Retina. Journal of Diabetes Research.
2019, 8463125-17.
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Chang, J., Shi, L., Ko, M. L., & Ko, G.
(2018).
Circadian Regulation of Mitochondrial Dynamics in Retinal Photoreceptors. World of Information Business Intelligence Reports. Albania.
33(2), 151-165.
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Shi, L., Chang, J., Yu, F., Ko, M. L., & Ko, G.
(2017).
The Contribution of L-Type Cav1.3 Channels to Retinal Light Responses. Frontiers in Molecular Neuroscience.
10, 394.
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Shi, L., Ko, M. L., & Ko, G.
(2017).
Retinoschisin Facilitates the Function of L-Type Voltage-Gated Calcium Channels. Frontiers in Cellular Neuroscience.
11, 232.
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Kim, A. J., Chang, J., Shi, L., Chang, R., Ko, M. L., & Ko, G.
(2017).
The Effects of Metformin on Obesity-Induced Dysfunctional Retinas. Invest Ophthalmol Vis Sci.
58(1), 106-118.
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Shi, L., Kim, A. J., Chang, R., Chang, J., Ying, W., Ko, M. L., Zhou, B., & Ko, G.
(2016).
Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice. PLoS ONE.
11(6), e0157543-e0157543.
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Huang, C., Shi, L., Lin, C., Kim, A. J., Ko, M. L., & Ko, G.
(2015).
A new role for AMP-activated protein kinase in the circadian regulation of L-type voltage-gated calcium channels in late-stage embryonic retinal photoreceptors. Journal of Neurochemistry.
135(4), 727-741.
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Shi, L., Ko, S., Ko, M. L., Kim, A. J., & Ko, G.
(2015).
Peptide Lv augments L-type voltage-gated calcium channels through vascular endothelial growth factor receptor 2 (VEGFR2) signaling. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics.
1853(5), 1154-1164.
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Chang, R., Shi, L., Huang, C., Kim, A. J., Ko, M. L., Zhou, B., & Ko, G.
(2015).
High-Fat Diet-Induced Retinal Dysfunction. Invest Ophthalmol Vis Sci.
56(4), 2367-2380.
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Chang, R., Shi, L., Huang, C., Kim, A. J., Ko, M. L., Zhou, B., & Ko, G.
(2015).
High-Fat DietInduced Retinal DysfunctionHigh-Fat DietInduced Retinal Dysfunction. Investigative Ophthalmology and Visual Science.
56(4), 2367-2380.
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Shi, L., Ko, M. L., Huang, C., Park, S., Hong, M., Wu, C., & Ko, G.
(2014).
Chicken embryos as a potential new model for early onset type I diabetes. Journal of Diabetes Research.
2014, 354094-10.
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Ko, M. L., Shi, L., Huang, C., Grushin, K., Park, S., & Ko, G.
(2013).
Circadian phase-dependent effect of nitric oxide on L-type voltage-gated calcium channels in avian cone photoreceptors. Journal of Neurochemistry.
127(3), 314-328.
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Huang, C., Ko, M. L., & Ko, G.
(2013).
A new functional role for mechanistic/mammalian target of rapamycin complex 1 (mTORC1) in the circadian regulation of L-type voltage-gated calcium channels in avian cone photoreceptors. PLoS ONE.
8(8), e73315-e73315.
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Shi, L., Ko, M. L., Abbott, L. C., & Ko, G.
(2012).
Identification of Peptide lv, a novel putative neuropeptide that regulates the expression of L-type voltage-gated calcium channels in photoreceptors. PLoS ONE.
7(8), e43091-e43091.
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Huang, C., Ko, M. L., Vernikovskaya, D. I., & Ko, G.
(2012).
Calcineurin serves in the circadian output pathway to regulate the daily rhythm of L-type voltage-gated calcium channels in the retina. Journal of Cellular Biochemistry.
113(3), 911-922.
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Ko, M. L., Shi, L., Tsai, J., Young, M. E., Neuendorff, N., Earnest, D. J., & Ko, G.
(2011).
Cardiac-specific mutation of Clock alters the quantitative measurements of physical activities without changing behavioral circadian rhythms. World of Information Business Intelligence Reports. Albania.
26(5), 412-422.
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Ko, M. L., Shi, L., Grushin, K., Nigussie, F., & Ko, G.
(2010).
Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathways. Chronobiology International: the journal of biological and medical rhythm research.
27(9-10), 1673-1696.
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Rocha, A., Jian, K., Ko, G., & Liang, H.
(2010).
Neuron adhesion and strengthening. Journal of Applied Physics.
108(2), 024702-024702.
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Shi, L., Ko, M. L., & Ko, G.
(2009).
Rhythmic expression of microRNA-26a regulates the L-type voltage-gated calcium channel alpha1C subunit in chicken cone photoreceptors. 284(38), 25791-25803.
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Jian, K., Barhoumi, R., Ko, M. L., & Ko, G.
(2009).
Inhibitory effect of somatostatin-14 on L-type voltage-gated calcium channels in cultured cone photoreceptors requires intracellular calcium. Journal of Neurophysiology.
102(3), 1801-1810.
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Ko, G., Shi, L., & Ko, M. L.
(2009).
Circadian regulation of ion channels and their functions. Journal of Neurochemistry.
110(4), 1150-1169.
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Ko, M. L., Jian, K., Shi, L., & Ko, G.
(2009).
Phosphatidylinositol 3 kinase-Akt signaling serves as a circadian output in the retina. Journal of Neurochemistry.
108(6), 1607-1620.
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Shi, L., Jian, K., Ko, M. L., Trump, D., & Ko, G.
(2009).
Retinoschisin, a new binding partner for L-type voltage-gated calcium channels in the retina. Journal of Biological Chemistry.
284(6), 3966-3975.
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Ko, M. L., Shi, L., & Ko, G.
(2009).
Circadian controls outweigh acute illumination effects on the activity of extracellular signal-regulated kinase (ERK) in the retina. NEUROSCIENCE LETTERS.
451(1), 74-78.
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Ko, M. L., Liu, Y., Shi, L., Trump, D., & Ko, G.
(2008).
Circadian regulation of retinoschisin in the chick retina. Investigative Ophthalmology and Visual Science.
49(4), 1615-1621.
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Chen, S., Ko, G., & Dryer, S. E.
(2007).
Somatostatin peptides produce multiple effects on gating properties of native cone photoreceptor cGMP-gated channels that depend on circadian phase and previous illumination. 27(45), 12168-12175.
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Ko, M. L., Liu, Y., Dryer, S. E., & Ko, G.
(2007).
The expression of L-type voltage-gated calcium channels in retinal photoreceptors is under circadian control. Journal of Neurochemistry.
103(2), 784-792.
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Chae, K., Ko, G., & Dryer, S. E.
(2007).
Tyrosine phosphorylation of cGMP-gated ion channels is under circadian control in chick retina photoreceptors. Investigative Ophthalmology and Visual Science.
48(2), 901-906.
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Ko, G., Ko, M., & Dryer, S. E.
(2004).
Circadian and cAMP-dependent modulation of retinal cone cGMP-gated channels does not require protein synthesis or calcium influx through L-type channels. BRAIN RESEARCH.
1021(2), 277-280.
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Ko, G., Ko, M. L., & Dryer, S. E.
(2004).
Circadian regulation of cGMP-gated channels of vertebrate cone photoreceptors: role of cAMP and Ras. 24(6), 1296-1304.
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Ko, G., Ko, M. L., & Dryer, S. E.
(2003).
Circadian phase-dependent modulation of cGMP-gated channels of cone photoreceptors by dopamine and D2 agonist. 23(8), 3145-3153.
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Ko, G. Y., Ko, M. L., & Dryer, S. E.
(2001).
Circadian regulation of cGMP-gated cationic channels of chick retinal cones. Erk MAP Kinase and Ca2+/calmodulin-dependent protein kinase II. Neuron.
29(1), 255-266.
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Ko, G. Y., Ko, M. L., & Dryer, S. E.
(2001).
Developmental expression of retinal cone cGMP-gated channels: evidence for rapid turnover and trophic regulation. 21(1), 221-229.
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Ko, G. Y., & Kelly, P. T.
(1999).
Nitric oxide acts as a postsynaptic signaling molecule in calcium/calmodulin-induced synaptic potentiation in hippocampal CA1 pyramidal neurons. 19(16), 6784-6794.
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Wang, J. H., Ko, G. Y., & Kelly, P. T.
(1997).
Cellular and molecular bases of memory: synaptic and neuronal plasticity. Journal of Clinical Neurophysiology.
14(4), 264-293.
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Ko, G. Y., Brown-Croyts, L. M., & Teyler, T. J.
(1997).
The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus. Brain Research Bulletin.
42(4), 297-302.
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Teyler, T. J., Cavus, I., Coussens, C., DiScenna, P., Grover, L., Lee, Y. P., & Little, Z.
(1994).
Multideterminant role of calcium in hippocampal synaptic plasticity. The Hippocampus.
4(6), 623-634.
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Teyler, T. J., Cavus, I., Coussens, C., DiScenna, P. G., Grover, L., Lee, Y., & Little, Z.
(1994).
18. Advances in understanding the mechanisms underlying synaptic plasticity. Journal of Neuroscience Methods.
52(1), a8-A8.
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Brown, L. M., Lee, Y. P., & Teyler, T. J.
(1994).
Antiepileptics inhibit cortical N-methyl-D-aspartate-evoked [3H]norepinephrine efflux. European Journal of Pharmacology.
254(3), 307-309.
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Pham, D., Niemi, A., Blank, R., & Ko, G.
(2022).
Abstract 11032: Peptide Lv Promotes the Trafficking and Membrane Insertion of Endothelial KCa31 Through the MEK1/ERK Pathway. Circulation.
146(Suppl_1), a11032-a11032.
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chapter
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Schurr, A., Rigor, B. M., Teyler, T. J., Cavus, I., Coussens, C., DiScenna, P., ... Little, Z.
(2020).
Advances in Understanding the Mechanisms Underlying Synaptic Plasticity. BRAIN SLICES in BASIC and CLINICAL RESEARCH.
(pp. 1-25).
Taylor & Francis.
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Ko, G.
(2017).
Circadian Regulation of Ion Channels in Photoreceptors. Reference Module in Neuroscience and Biobehavioral Psychology.
Elsevier.
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Ko, G., JIan, K., Shi, L., & Ko, M. L.
(2011).
Circadian regulation of ion channels in photoreceptors. Besharse, J. C., & Bok, D. (Eds.),
The Retina and its Disorders.
(pp. 118-123).
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Ko, G., Jian, K., Shi, L., & Ko, M. L.
(2010).
Circadian Regulation of Ion Channels in Photoreceptors. Encyclopedia of the Eye.
(pp. 296-301).
Elsevier.
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Schurr, A., Rigor, B. M., Teyler, T. J., Cavus, I., Coussens, C., DiScenna, P., ... Little, Z.
(2020).
Advances in Understanding the Mechanisms Underlying Synaptic Plasticity. BRAIN SLICES in BASIC and CLINICAL RESEARCH.
(pp. 1-25).
Taylor & Francis.
Research
principal investigator on
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- BIMS491 Research Instructor
- NFSC485 Hnr-directed Studies Instructor
- NRSC101 Neuroscience Overview Instructor
- NRSC277 Essential Neuroscience Instructor
- NRSC450 Mammal Function Neuro Instructor
- NRSC485 Directed Studies Instructor
- NRSC491 Hnr-research Instructor
- NRSC681 Seminar Instructor
- NRSC685 Directed Studies Instructor
- NRSC691 Research Instructor
- VIBS101 Neuroscience Overview Instructor
- VIBS102 Scientific Notations Neurosci Instructor
- VIBS277 Essential Neuroscience Instructor
- VIBS285 Directed Studies Instructor
- VIBS289 Sptp: Neuroscience 101 Instructor
- VIBS450 Mammal Function Neuro Instructor
- VIBS485 Directed Studies Instructor
- VIBS489 Sptp: Neuroscience 101 Instructor
- VIBS685 Directed Studies Instructor
- VIBS691 Research Instructor
Works By Students
chaired theses and dissertations
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Chang, Ya-An (2018-10). The Efficacy of Melatonin in Protecting Neural Retina and Retinal Microvasculature in Early Diabetes.
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Huang, Chia-Yu (2014-11). Circadian Regulation of L-Type Voltage-Gated Calcium Channels in Avian Retina.
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Kim, Jeesu (2017-07). The Effects of Metformin on Obesity-Induced Diabetic Retinas.
Background
education and training
- Ph.D. in Neuroscience, Kent State University - (Kent, Ohio, United States) 1996
awards and honors
Contact
first name
- Gladys
has last name
- Ko
mailing address
-
Texas A&M University
Veterinary Integrative Biosciences
4458 TAMU
College Station, TX 77843-4458
USA
Other
- gko@tamu.edu