selected publications academic article Pham, D., Niemi, A., Blank, R., & Ko, G. (2022). Abstract 11032: Peptide Lv Promotes the Trafficking and Membrane Insertion of Endothelial KCa31 Through the MEK1/ERK Pathway. Circulation. 146(Suppl_1), a11032-a11032. Ko, G., Yu, F., Bayless, K. J., & Ko, M. L. (2022). MicroRNA-150 (miR-150) and Diabetic Retinopathy: Is miR-150 Only a Biomarker or Does It Contribute to Disease Progression?. 23(20), 12099-12099. McCauley, N., Lawless, L., Basra, M., DePadova, N., Loyola, X. A., Zhou, H., ... Xie, L. (2022). In ovo exposure to cadmium causes right ventricle hyperplasia due to cell proliferation of cardiomyocytes. Toxicology Letters. 366, 1-6. Uppada, S., Zou, D., Scott, E. M., Ko, G., Pflugfelder, S., Kumar, M., & Ganugula, R. (2022). Paclitaxel and Urolithin A Prevent Histamine-Induced Neurovascular Breakdown Alike, in an Ex Vivo Rat Eye Model. ACS Chemical Neuroscience. 13(14), 2092-2098. Pham, D. L., Niemi, A., Ko, M. L., & Ko, G. (2022). Peptide Lv augments intermediate-conductance calcium-dependent potassium channels (KCa3.1) in endothelial cells to promote angiogenesis. PLoS ONE. 17(10), e0276744-e0276744. Yu, F., Ko, M. L., & Ko, G. (2021). MicroRNA-150 and its target ETS-domain transcription factor 1 contribute to inflammation in diabetic photoreceptors. Journal of Cellular and Molecular Medicine. 25(22), 10724-10735. Yu, F., Ko, M. L., & Ko, G. (2021). Decreased MicroRNA-150 Exacerbates Neuronal Apoptosis in the Diabetic Retina. Biomedicines. 9(9), 1135-1135. Ding, Z., Zhou, H., McCauley, N., Ko, G., Zhang, K. K., & Xie, L. (2020). In ovo hyperglycemia causes congenital limb defects in chicken embryos via disruption of cell proliferation and apoptosis. BBA: Molecular Basis of Disease. 1866(12), 165955-165955. Yu, F., Chapman, S., Pham, D. L., Ko, M. L., Zhou, B., & Ko, G. (2020). Decreased miR-150 in obesity-associated type 2 diabetic mice increases intraocular inflammation and exacerbates retinal dysfunction. BMJ Open Diabetes Research and Care. 8(1), e001446-e001446. Ko, G. (2020). Circadian regulation in the retina: From molecules to network. European Journal of Neuroscience. 51(1), 194-216. Raghunathan, S., Islas, J. F., Mistretta, B., Iyer, D., Shi, L., Gunaratne, P. H., ... McConnell, B. K. (2020). Conversion of human cardiac progenitor cells into cardiac pacemaker-like cells. Journal of Molecular and Cellular Cardiology. 138, 12-22. Shi, L., Zhao, M., Abbey, C. A., Tsai, S., Xie, W., Pham, D., ... Ko, G. (2019). Newly Identified Peptide, Peptide Lv, Promotes Pathological Angiogenesis. Journal of the American Heart Association. 8(22), e013673. Chang, J., Yu, F., Shi, L., Ko, M. L., & Ko, G. (2019). Melatonin Affects Mitochondrial Fission/Fusion Dynamics in the Diabetic Retina. Journal of Diabetes Research. 2019, 8463125-17. Chang, J., Shi, L., Ko, M. L., & Ko, G. (2018). Circadian Regulation of Mitochondrial Dynamics in Retinal Photoreceptors. World of Information Business Intelligence Reports. Albania. 33(2), 151-165. Shi, L., Chang, J., Yu, F., Ko, M. L., & Ko, G. (2017). The Contribution of L-Type Cav1.3 Channels to Retinal Light Responses. Frontiers in Molecular Neuroscience. 10, 394. Shi, L., Ko, M. L., & Ko, G. (2017). Retinoschisin Facilitates the Function of L-Type Voltage-Gated Calcium Channels. Frontiers in Cellular Neuroscience. 11, 232. Kim, A. J., Chang, J., Shi, L., Chang, R., Ko, M. L., & Ko, G. (2017). The Effects of Metformin on Obesity-Induced Dysfunctional Retinas. Invest Ophthalmol Vis Sci. 58(1), 106-118. Shi, L., Kim, A. J., Chang, R., Chang, J., Ying, W., Ko, M. L., Zhou, B., & Ko, G. (2016). Deletion of miR-150 Exacerbates Retinal Vascular Overgrowth in High-Fat-Diet Induced Diabetic Mice. PLoS ONE. 11(6), e0157543-e0157543. Huang, C., Shi, L., Lin, C., Kim, A. J., Ko, M. L., & Ko, G. (2015). A new role for AMP-activated protein kinase in the circadian regulation of L-type voltage-gated calcium channels in late-stage embryonic retinal photoreceptors. Journal of Neurochemistry. 135(4), 727-741. Shi, L., Ko, S., Ko, M. L., Kim, A. J., & Ko, G. (2015). Peptide Lv augments L-type voltage-gated calcium channels through vascular endothelial growth factor receptor 2 (VEGFR2) signaling. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 1853(5), 1154-1164. Chang, R., Shi, L., Huang, C., Kim, A. J., Ko, M. L., Zhou, B., & Ko, G. (2015). High-Fat Diet-Induced Retinal Dysfunction. Invest Ophthalmol Vis Sci. 56(4), 2367-2380. Chang, R., Shi, L., Huang, C., Kim, A. J., Ko, M. L., Zhou, B., & Ko, G. (2015). High-Fat DietInduced Retinal DysfunctionHigh-Fat DietInduced Retinal Dysfunction. Investigative Ophthalmology and Visual Science. 56(4), 2367-2380. Shi, L., Ko, M. L., Huang, C., Park, S., Hong, M., Wu, C., & Ko, G. (2014). Chicken embryos as a potential new model for early onset type I diabetes. Journal of Diabetes Research. 2014, 354094-10. Ko, M. L., Shi, L., Huang, C., Grushin, K., Park, S., & Ko, G. (2013). Circadian phase-dependent effect of nitric oxide on L-type voltage-gated calcium channels in avian cone photoreceptors. Journal of Neurochemistry. 127(3), 314-328. Huang, C., Ko, M. L., & Ko, G. (2013). A new functional role for mechanistic/mammalian target of rapamycin complex 1 (mTORC1) in the circadian regulation of L-type voltage-gated calcium channels in avian cone photoreceptors. PLoS ONE. 8(8), e73315-e73315. Shi, L., Ko, M. L., Abbott, L. C., & Ko, G. (2012). Identification of Peptide lv, a novel putative neuropeptide that regulates the expression of L-type voltage-gated calcium channels in photoreceptors. PLoS ONE. 7(8), e43091-e43091. Huang, C., Ko, M. L., Vernikovskaya, D. I., & Ko, G. (2012). Calcineurin serves in the circadian output pathway to regulate the daily rhythm of L-type voltage-gated calcium channels in the retina. Journal of Cellular Biochemistry. 113(3), 911-922. Ko, M. L., Shi, L., Tsai, J., Young, M. E., Neuendorff, N., Earnest, D. J., & Ko, G. (2011). Cardiac-specific mutation of Clock alters the quantitative measurements of physical activities without changing behavioral circadian rhythms. World of Information Business Intelligence Reports. Albania. 26(5), 412-422. Ko, M. L., Shi, L., Grushin, K., Nigussie, F., & Ko, G. (2010). Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathways. Chronobiology International: the journal of biological and medical rhythm research. 27(9-10), 1673-1696. Rocha, A., Jian, K., Ko, G., & Liang, H. (2010). Neuron adhesion and strengthening. Journal of Applied Physics. 108(2), 024702-024702. Shi, L., Ko, M. L., & Ko, G. (2009). Rhythmic expression of microRNA-26a regulates the L-type voltage-gated calcium channel alpha1C subunit in chicken cone photoreceptors. 284(38), 25791-25803. Jian, K., Barhoumi, R., Ko, M. L., & Ko, G. (2009). Inhibitory effect of somatostatin-14 on L-type voltage-gated calcium channels in cultured cone photoreceptors requires intracellular calcium. Journal of Neurophysiology. 102(3), 1801-1810. Ko, G., Shi, L., & Ko, M. L. (2009). Circadian regulation of ion channels and their functions. Journal of Neurochemistry. 110(4), 1150-1169. Ko, M. L., Jian, K., Shi, L., & Ko, G. (2009). Phosphatidylinositol 3 kinase-Akt signaling serves as a circadian output in the retina. Journal of Neurochemistry. 108(6), 1607-1620. Shi, L., Jian, K., Ko, M. L., Trump, D., & Ko, G. (2009). Retinoschisin, a new binding partner for L-type voltage-gated calcium channels in the retina. Journal of Biological Chemistry. 284(6), 3966-3975. Ko, M. L., Shi, L., & Ko, G. (2009). Circadian controls outweigh acute illumination effects on the activity of extracellular signal-regulated kinase (ERK) in the retina. NEUROSCIENCE LETTERS. 451(1), 74-78. Ko, M. L., Liu, Y., Shi, L., Trump, D., & Ko, G. (2008). Circadian regulation of retinoschisin in the chick retina. Investigative Ophthalmology and Visual Science. 49(4), 1615-1621. Chen, S., Ko, G., & Dryer, S. E. (2007). Somatostatin peptides produce multiple effects on gating properties of native cone photoreceptor cGMP-gated channels that depend on circadian phase and previous illumination. 27(45), 12168-12175. Ko, M. L., Liu, Y., Dryer, S. E., & Ko, G. (2007). The expression of L-type voltage-gated calcium channels in retinal photoreceptors is under circadian control. Journal of Neurochemistry. 103(2), 784-792. Chae, K., Ko, G., & Dryer, S. E. (2007). Tyrosine phosphorylation of cGMP-gated ion channels is under circadian control in chick retina photoreceptors. Investigative Ophthalmology and Visual Science. 48(2), 901-906. Ko, G., Ko, M., & Dryer, S. E. (2004). Circadian and cAMP-dependent modulation of retinal cone cGMP-gated channels does not require protein synthesis or calcium influx through L-type channels. BRAIN RESEARCH. 1021(2), 277-280. Ko, G., Ko, M. L., & Dryer, S. E. (2004). Circadian regulation of cGMP-gated channels of vertebrate cone photoreceptors: role of cAMP and Ras. 24(6), 1296-1304. Ko, G., Ko, M. L., & Dryer, S. E. (2003). Circadian phase-dependent modulation of cGMP-gated channels of cone photoreceptors by dopamine and D2 agonist. 23(8), 3145-3153. Ko, G. Y., Ko, M. L., & Dryer, S. E. (2001). Circadian regulation of cGMP-gated cationic channels of chick retinal cones. Erk MAP Kinase and Ca2+/calmodulin-dependent protein kinase II. Neuron. 29(1), 255-266. Ko, G. Y., Ko, M. L., & Dryer, S. E. (2001). Developmental expression of retinal cone cGMP-gated channels: evidence for rapid turnover and trophic regulation. 21(1), 221-229. Ko, G. Y., & Kelly, P. T. (1999). Nitric oxide acts as a postsynaptic signaling molecule in calcium/calmodulin-induced synaptic potentiation in hippocampal CA1 pyramidal neurons. 19(16), 6784-6794. Wang, J. H., Ko, G. Y., & Kelly, P. T. (1997). Cellular and molecular bases of memory: synaptic and neuronal plasticity. Journal of Clinical Neurophysiology. 14(4), 264-293. Ko, G. Y., Brown-Croyts, L. M., & Teyler, T. J. (1997). The effects of anticonvulsant drugs on NMDA-EPSP, AMPA-EPSP, and GABA-IPSP in the rat hippocampus. Brain Research Bulletin. 42(4), 297-302. Teyler, T. J., Cavus, I., Coussens, C., DiScenna, P., Grover, L., Lee, Y. P., & Little, Z. (1994). Multideterminant role of calcium in hippocampal synaptic plasticity. The Hippocampus. 4(6), 623-634. Teyler, T. J., Cavus, I., Coussens, C., DiScenna, P. G., Grover, L., Lee, Y., & Little, Z. (1994). 18. Advances in understanding the mechanisms underlying synaptic plasticity. Journal of Neuroscience Methods. 52(1), a8-A8. Brown, L. M., Lee, Y. P., & Teyler, T. J. (1994). Antiepileptics inhibit cortical N-methyl-D-aspartate-evoked [3H]norepinephrine efflux. European Journal of Pharmacology. 254(3), 307-309. chapter Schurr, A., Rigor, B. M., Teyler, T. J., Cavus, I., Coussens, C., DiScenna, P., ... Little, Z. (2020). Advances in Understanding the Mechanisms Underlying Synaptic Plasticity. BRAIN SLICES in BASIC and CLINICAL RESEARCH. (pp. 1-25). Taylor & Francis. Ko, G. (2017). Circadian Regulation of Ion Channels in Photoreceptors. Reference Module in Neuroscience and Biobehavioral Psychology. Elsevier. Ko, G., JIan, K., Shi, L., & Ko, M. L. (2011). Circadian regulation of ion channels in photoreceptors. Besharse, J. C., & Bok, D. (Eds.), The Retina and its Disorders. (pp. 118-123). Ko, G., Jian, K., Shi, L., & Ko, M. L. (2010). Circadian Regulation of Ion Channels in Photoreceptors. Encyclopedia of the Eye. (pp. 296-301). Elsevier.
principal investigator on Functional interactions among retinoschisin and its binding partners awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2013 - 2016
teaching activities BICH491 Hnr-research Instructor BIMS491 Hnr-research Instructor NFSC485 Hnr-directed Studies Instructor NRSC101 Neuroscience Overview Instructor NRSC277 Essential Neuroscience Instructor NRSC450 Mammal Function Neuro Instructor NRSC485 Directed Studies Instructor NRSC491 Hnr-research Instructor NRSC681 Seminar Instructor NRSC685 Directed Studies Instructor NRSC691 Research Instructor VIBS101 Neuroscience Overview Instructor VIBS102 Scientific Notations Neurosci Instructor VIBS277 Essential Neuroscience Instructor VIBS285 Directed Studies Instructor VIBS289 Sptp: Neuroscience 101 Instructor VIBS450 Mammal Function Neuro Instructor VIBS485 Directed Studies Instructor VIBS489 Sptp: Neuroscience 101 Instructor VIBS685 Directed Studies Instructor VIBS691 Research Instructor
chaired theses and dissertations Chang, Ya-An (2018-10). The Efficacy of Melatonin in Protecting Neural Retina and Retinal Microvasculature in Early Diabetes. Huang, Chia-Yu (2014-11). Circadian Regulation of L-Type Voltage-Gated Calcium Channels in Avian Retina. Kim, Jeesu (2017-07). The Effects of Metformin on Obesity-Induced Diabetic Retinas.
education and training Ph.D. in Neuroscience, Kent State University - (Kent, Ohio, United States) 1996
awards and honors Montague Center for Teaching Excellence (CTE) Scholar, conferred by Texas A&M University - (College Station, Texas, United States), 2007
mailing address Texas A&M University Veterinary Integrative Biosciences 4458 TAMU College Station, TX 77843-4458 USA