This paper studies the vibration mitigation of a sandwich beam with tip mass using piezoelectric active control. The core of the sandwich beam is made of foam and the face sheets are made of steel with a bonded piezoelectric actuator and sensor. The three-layer sandwich beam is clamped at one end and carries a payload at the other end. The tip mass is such that its center of mass is offset from the point of attachment. The extended higher-order sandwich panel (HSAPT) theory is employed in conjunction with the Hamilton’s principle to derive the governing equations of motion and boundary conditions. The obtained partial differential equations are solved using the generalized differential quadrature (GDQ) method. Free and forced vibration analyses are carried out and the results are compared with those obtained from the use of the commercial finite element software ANSYS. Derivative feedback control algorithm is employed to control the vibration of the system. Parametric studies are conducted to examine the arrangement impact of the piezoelectric sensors and actuators on the system vibrational behavior.