A left ventricle model to predict post-revascularization ejection fraction based on cine magnetic resonance images. Academic Article

abstract

• The left ventricular ejection fraction (LVEF) is an important clinical indicator of the cardiac function and long-term outcome for patients with coronary artery disease. A biomechanical model of the left ventricle was developed to quantitatively predict post-revascularization LVEF based on noninvasive magnetic resonance imaging. The myocardium was categorized into normal, hibernating, and infarcted regions from the ventricular short-axis images. Assuming that hibernating tissue would potentially regain contractility after revascularization, the expected maximum post-revascularization LVEF was calculated for four patients with chronic left ventricular dysfunction. The predictions were within three ejection fraction points of the follow-up LVEFs. This model may be useful to estimate the outcome and efficacy of revascularization plans.

authors

• Pettigrew, Roderic

published proceedings

• J Biomech Eng

author list (cited authors)

• Han, H., Oshinski, J. N., Ku, D. N., & Pettigrew, R. I.

citation count

• 8

complete list of authors

• Han, Hai-Chao||Oshinski, John N||Ku, David N||Pettigrew, Roderic I

publication date

• February 2002

publisher

• ASME International  Publisher

published in

• Journal of Biomechanical Engineering  Journal

keywords

• Heart Ventricles
• Humans
• Image Processing, Computer-Assisted
• Magnetic Resonance Imaging, Cine
• Models, Cardiovascular
• Myocardial Contraction
• Myocardial Revascularization
• Myocardium
• Predictive Value Of Tests
• Stroke Volume
• Tissue Survival
• Treatment Outcome
• Ventricular Dysfunction, Left

PubMed Central ID

• 11871605

Digital Object Identifier (DOI)

• 10.1115/1.1428555

start page

• 52

end page

• 55

volume

• 124

issue

• 1

URL

• http://dx.doi.org/10.1115/1.1428555