Relation between growth and replication in bacteria. Academic Article uri icon


  • The control of chromosome replication in bacteria depends on the cell growth; a round of replication is initiated when the cell mass (or protein) per replication origin has reached a certain critical level. Relative values of this "initiation mass" have previously been estimated from the evaluation of experiments involving age fractionation of radioactively labelled bacterial cultures. Here a theoretical analysis is presented which permits a simple and accurate method to determine this initiation mass from a few parameters easily observable with exponential cultures, without the need for age fractionation. 1979.

published proceedings

  • J Theor Biol

author list (cited authors)

  • Bremer, H., Churchward, G., & Young, R.

citation count

  • 28

complete list of authors

  • Bremer, H||Churchward, G||Young, R

publication date

  • January 1979