Relation between growth and replication in bacteria.

abstract

• The control of chromosome replication in bacteria depends on the cell growth; a round of replication is initiated when the cell mass (or protein) per replication origin has reached a certain critical level. Relative values of this "initiation mass" have previously been estimated from the evaluation of experiments involving age fractionation of radioactively labelled bacterial cultures. Here a theoretical analysis is presented which permits a simple and accurate method to determine this initiation mass from a few parameters easily observable with exponential cultures, without the need for age fractionation. 1979.

authors

• Young, Ryland

published proceedings

• J Theor Biol

author list (cited authors)

• Bremer, H., Churchward, G., & Young, R.

citation count

• 28

complete list of authors

• Bremer, H||Churchward, G||Young, R

publication date

• January 1979

publisher

• Elsevier  Publisher

published in

• Journal of Theoretical Biology  Journal

keywords

• Bacteria
• Bacterial Proteins
• Cell Division
• Chromosomes, Bacterial
• DNA Replication
• DNA, Bacterial
• Models, Biological
• Time Factors

Digital Object Identifier (DOI)

• 10.1016/0022-5193(79)90051-1

start page

• 533

end page

• 545

volume

• 81

issue

• 3

URL

• http://dx.doi.org/10.1016/0022-5193(79)90051-1