Phages will out: strategies of host cell lysis. Academic Article uri icon


  • Most phages accomplish host lysis using a muralytic enzyme, or endolysin, and a holin, which permeabilizes the membrane at a programmed time and thus controls the length of the vegetative cycle. By contrast, lytic single-stranded RNA and DNA phages accomplish lysis by producing a single lysis protein without muralytic activity.

published proceedings

  • Trends Microbiol

altmetric score

  • 3

author list (cited authors)

  • Young, I., Wang, I., & Roof, W. D.

citation count

  • 319

complete list of authors

  • Young, I||Wang, I||Roof, WD

publication date

  • January 2000