The role of olfactory stimulus in adult mammalian neurogenesis. Academic Article

abstract

• Neurogenesis occurs in the adult mammalian brain in discrete regions related to olfactory sensory signaling and integration. The olfactory receptor cell population is in constant turn-over through local progenitor cells. Also, newborn neurons are added to the olfactory bulbs through a major migratory route from the subventricular zone, the rostral migratory stream. The olfactory bulbs project to different brain structures, including: piriform cortex, amygdala, entorhinal cortex, striatum and hippocampus. These structures play important roles in odor identification, feeding behavior, social interactions, reproductive behavior, behavioral reinforcement, emotional responses, learning and memory. In all of these regions neurogenesis has been described in normal and in manipulated mammalian brain. These data are reviewed in the context of a sensory-behavioral hypothesis on adult neurogenesis that olfactory input modulates neurogenesis in many different regions of the brain.

authors

• Shapiro, Lee

published proceedings

• Behav Brain Res

author list (cited authors)

• Arisi, G. M., Foresti, M. L., Mukherjee, S., & Shapiro, L. A.

citation count

• 26

complete list of authors

• Arisi, Gabriel M||Foresti, Maira L||Mukherjee, Sanjib||Shapiro, Lee A

publication date

• January 2012

publisher

• Elsevier  Publisher

published in

• Behavioural Brain Research  Journal

keywords

• Amygdala
• Animals
• Cell Movement
• Cell Proliferation
• Emotions
• Feeding Behavior
• Hippocampus
• Learning
• Neurogenesis
• Odorants
• Olfactory Bulb
• Olfactory Pathways
• Olfactory Receptor Neurons
• Social Behavior

Digital Object Identifier (DOI)

• 10.1016/j.bbr.2011.03.050

start page

• 356

end page

• 362

volume

• 227

issue

• 2

URL

• http://dx.doi.org/10.1016/j.bbr.2011.03.050