HR job title
- Professor
- Contact Info
- 1 979 862 1332
Golding, Michael Associate Professor
Positions
- Associate Professor, Veterinary Physiology and Pharmacology, School of Veterinary Medicine and Biomedical Sciences
- Overview
- Publications
- Research
- Teaching
- Works By Students
- Background
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Overview
Publications
selected publications
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academic article
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Thomas, K. N., Derrico, D. D., & Golding, M. C.
(2023).
Paternal alcohol exposure and dental-facial anomalies in offspring. Reply. Journal of Clinical Investigation.
133(19), e174216.
-
Thomas, K. N., Srikanth, N., Bhadsavle, S. S., Thomas, K. R., Zimmel, K. N., Basel, A., ... Golding, M. C.
(2023).
Preconception paternal ethanol exposures induce alcohol-related craniofacial growth deficiencies in fetal offspring. Journal of Clinical Investigation.
133(11), e167624.
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Roach, A. N., Zimmel, K. N., Thomas, K. N., Basel, A., Bhadsavle, S. S., & Golding, M. C.
(2023).
Preconception paternal alcohol exposure decreases IVF embryo survival and pregnancy success rates in a mouse model. Molecular Human Reproduction.
29(2), gaad002.
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Bedi, Y. S., Wang, H., Thomas, K. N., Basel, A., Prunier, J., Robert, C., & Golding, M. C.
(2022).
Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming. Scientific Reports.
12(1), 8839.
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Bedi, Y. S., Roach, A. N., Thomas, K. N., Mehta, N. A., & Golding, M. C.
(2022).
Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome. Epigenetics and Chromatin.
15(1), 2.
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Behlen, J. C., Lau, C. H., Pendleton, D., Li, Y., Hoffmann, A. R., Golding, M. C., Zhang, R., & Johnson, N. M.
(2022).
NRF2-Dependent Placental Effects Vary by Sex and Dose following Gestational Exposure to Ultrafine Particles. Antioxidants.
11(2), 352-352.
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Thomas, K. N., Zimmel, K. N., Basel, A., Roach, A. N., Mehta, N. A., Thomas, K. R., ... Golding, M. C.
(2022).
Paternal alcohol exposures program intergenerational hormetic effects on offspring fetoplacental growth. Frontiers in Cell and Developmental Biology.
10, 930375.
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Bhadsavle, S. S., & Golding, M. C.
(2022).
Paternal epigenetic influences on placental health and their impacts on offspring development and disease. Frontiers in Genetics.
13, 1068408.
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Thomas, K. N., Zimmel, K. N., Roach, A. N., Basel, A., Mehta, N. A., Bedi, Y. S., & Golding, M. C.
(2021).
Maternal background alters the penetrance of growth phenotypes and sex-specific placental adaptation of offspring sired by alcohol-exposed males. 35(12), e22035.
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Behlen, J. C., Lau, C. H., Li, Y., Dhagat, P., Stanley, J. A., Rodrigues Hoffman, A., ... Johnson, N. M.
(2021).
Gestational Exposure to Ultrafine Particles Reveals Sex- and Dose-Specific Changes in Offspring Birth Outcomes, Placental Morphology, and Gene Networks. TOXICOLOGICAL SCIENCES.
184(2), 204-213.
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Chang, R. C., Thomas, K. N., Mehta, N. A., Veazey, K. J., Parnell, S. E., & Golding, M. C.
(2021).
Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription. Epigenetics and Chromatin.
14(1), 27.
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Pinzon-Arteaga, C., Snyder, M. D., Lazzarotto, C. R., Moreno, N. F., Juras, R., Raudsepp, T., ... Long, C. R.
(2020).
Efficient correction of a deleterious point mutation in primary horse fibroblasts with CRISPR-Cas9. Scientific Reports.
10(1), 7411.
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Mustapha, T. A., Chang, R. C., Garcia-Rhodes, D., Pendleton, D., Johnson, N. M., & Golding, M. C.
(2020).
Gestational exposure to particulate air pollution exacerbates the growth phenotypes induced by preconception paternal alcohol use: a multiplex model of exposure. Environmental Epigenetics.
6(1), dvaa011.
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Rychlik, K. A., Secrest, J. R., Lau, C., Pulczinski, J., Zamora, M. L., Leal, J., ... Johnson, N. M.
(2019).
In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression. Proceedings of the National Academy of Sciences of the United States of America.
116(9), 3443-3448.
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Bedi, Y., Chang, R. C., Gibbs, R., Clement, T. M., & Golding, M. C.
(2019).
Alterations in sperm-inherited noncoding RNAs associate with late-term fetal growth restriction induced by preconception paternal alcohol use. Reproductive Toxicology.
87, 11-20.
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Chang, R. C., Wang, H., Bedi, Y., & Golding, M. C.
(2019).
Preconception paternal alcohol exposure exerts sex-specific effects on offspring growth and long-term metabolic programming. Epigenetics and Chromatin.
12(1), 9.
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Chang, R. C., Thomas, K. N., Bedi, Y. S., & Golding, M. C.
(2019).
Programmed increases in LXR induced by paternal alcohol use enhance offspring metabolic adaptation to high-fat diet induced obesity. Molecular Metabolism.
30, 161-172.
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Sachani, S. S., Landschoot, L. S., Zhang, L., White, C. R., MacDonald, W. A., Golding, M. C., & Mann, M.
(2018).
Nucleoporin 107, 62 and 153 mediate Kcnq1ot1 imprinted domain regulation in extraembryonic endoderm stem cells. Nature Communications.
9(1), 2795.
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Skiles, W. M., Kester, A., Pryor, J. H., Westhusin, M. E., Golding, M. C., & Long, C. R.
(2018).
Oxygen-induced alterations in the expression of chromatin modifying enzymes and the transcriptional regulation of imprinted genes. Gene Expression Patterns.
28, 1-11.
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Chang, R. C., Skiles, W. M., Chronister, S. S., Wang, H., Sutton, G. I., Bedi, Y. S., ... Golding, M. C.
(2017).
DNA methylation-independent growth restriction and altered developmental programming in a mouse model of preconception male alcohol exposure. Epigenetics.
12(10), 841-853.
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Veazey, K. J., Wang, H., Bedi, Y. S., Skiles, W. M., Chang, R., & Golding, M. C.
(2017).
Disconnect between alcohol-induced alterations in chromatin structure and gene transcription in a mouse embryonic stem cell model of exposure. ALCOHOL.
60, 121-133.
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Lunde, E. R., Washburn, S. E., Golding, M. C., Bake, S., Miranda, R. C., & Ramadoss, J.
(2016).
Alcohol-Induced Developmental Origins of Adult-Onset Diseases. Alcoholism: Clinical and Experimental Research.
40(7), 1403-1414.
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Ying, W., Tseng, A., Chang, R., Wang, H., Lin, Y., Kanameni, S., ... Zhou, B.
(2016).
miR-150 regulates obesity-associated insulin resistance by controlling B cell functions. Scientific Reports.
6(1), 20176.
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Singh, N., Ramrez-Carvajal, L., de Los Santos, T., Golding, M. C., & Long, C. R.
(2016).
Inhibition of EHMT2 Induces a Robust Antiviral Response Against Foot-and-Mouth Disease and Vesicular Stomatitis Virus Infections in Bovine Cells. Journal of Interferon and Cytokine Research.
36(1), 37-47.
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Veazey, K. J., Parnell, S. E., Miranda, R. C., & Golding, M. C.
(2015).
Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects. Epigenetics and Chromatin.
8(1), 39.
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Ying, W., Tseng, A., Chang, R., Morin, A., Brehm, T., Triff, K., ... Zhou, B.
(2015).
MicroRNA-223 is a crucial mediator of PPAR-regulated alternative macrophage activation. Journal of Clinical Investigation.
125(11), 4149-4159.
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Golding, M. C., Snyder, M., Williamson, G. L., Veazey, K. J., Peoples, M., Pryor, J. H., Westhusin, M. E., & Long, C. R.
(2015).
Histone-lysine N-methyltransferase SETDB1 is required for development of the bovine blastocyst. THERIOGENOLOGY.
84(8), 1411-1422.
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Long, C. R., Westhusin, M. E., & Golding, M. C.
(2014).
Reshaping the transcriptional frontier: epigenetics and somatic cell nuclear transfer. Molecular Reproduction and Development.
81(2), 183-193.
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Veazey, K. J., Muller, D., & Golding, M. C.
(2013).
Prenatal alcohol exposure and cellular differentiation: a role for Polycomb and Trithorax group proteins in FAS phenotypes?. 35(1), 77-85.
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Veazey, K. J., Carnahan, M. N., Muller, D., Miranda, R. C., & Golding, M. C.
(2013).
Alcohol-induced epigenetic alterations to developmentally crucial genes regulating neural stemness and differentiation. Alcoholism: Clinical and Experimental Research.
37(7), 1111-1122.
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Carnahan, M. N., Veazey, K. J., Muller, D., Tingling, J. D., Miranda, R. C., & Golding, M. C.
(2013).
Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure. ALCOHOL.
47(2), 109-120.
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Golding, M. C.
(2012).
Generation of trophoblast stem cells. Methods in molecular biology (Clifton, N.J.).
925, 49-59.
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Tessanne, K., Golding, M. C., Long, C. R., Peoples, M. D., Hannon, G., & Westhusin, M. E.
(2012).
Production of transgenic calves expressing an shRNA targeting myostatin. Molecular Reproduction and Development.
79(3), 176-185.
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Golding, M. C., Magri, L. S., Zhang, L., Lalone, S. A., Higgins, M. J., & Mann, M.
(2011).
Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells. Development.
138(17), 3667-3678.
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Golding, M. C., Williamson, G. L., Stroud, T. K., Westhusin, M. E., & Long, C. R.
(2011).
Examination of DNA methyltransferase expression in cloned embryos reveals an essential role for Dnmt1 in bovine development. Molecular Reproduction and Development.
78(5), 306-317.
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Golding, M. C., & Mann, M.
(2011).
A bidirectional promoter architecture enhances lentiviral transgenesis in embryonic and extraembryonic stem cells. Gene Therapy (Basingstoke).
18(8), 817-826.
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Veazey, K. J., & Golding, M. C.
(2011).
Selection of stable reference genes for quantitative rt-PCR comparisons of mouse embryonic and extra-embryonic stem cells. PLoS ONE.
6(11), e27592-e27592.
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Long, C. R., Tessanne, K. J., & Golding, M. C.
(2010).
Applications of RNA interference-based gene silencing in animal agriculture. Reproduction, Fertility and Development.
22(1), 47-58.
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Golding, M. C., Zhang, L., & Mann, M.
(2010).
Multiple epigenetic modifiers induce aggressive viral extinction in extraembryonic endoderm stem cells. Cell Stem Cell.
6(5), 457-467.
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Silva, J. M., Marran, K., Parker, J. S., Silva, J., Golding, M., Schlabach, M. R., ... Chang, K.
(2008).
Profiling Essential Genes in Human Mammary Cells by Multiplex RNAi Screening. Science.
319(5863), 617-620.
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Kuzmin, A., Han, Z., Golding, M. C., Mann, M., Latham, K. E., & Varmuza, S.
(2008).
The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues. Gene Expression Patterns.
8(2), 107-116.
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Willingham-Rocky, L. A., Golding, M. C., Wright, J. M., Kraemer, D. C., Westhusin, M. E., & Burghardt, R. C.
(2007).
Cloning of GJA1 (connexin43) and its expression in canine ovarian follicles throughout the estrous cycle. Gene Expression Patterns.
7(1-2), 66-71.
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Golding, M. C., Long, C. R., Carmell, M. A., Hannon, G. J., & Westhusin, M. E.
(2006).
Suppression of prion protein in livestock by RNA interference. Proceedings of the National Academy of Sciences of the United States of America.
103(14), 5285-5290.
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Harrington, J. R., Golding, M. C., Martens, R. J., Halbert, N. D., & Cohen, N. D.
(2005).
Evaluation of a real-time quantitative polymerase chain reaction assay for detection and quantitation of virulent Rhodococcus equi. American Journal of Veterinary Research.
66(5), 755-761.
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Silva, J. M., Li, M. Z., Chang, K., Ge, W., Golding, M. C., Rickles, R. J., ... Hannon, G. J.
(2005).
Second-generation shRNA libraries covering the mouse and human genomes. Nature Genetics.
37(11), 1281-1288.
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Golding, M. C., & Westhusin, M. E.
(2003).
Analysis of DNA (cytosine 5) methyltransferase mRNA sequence and expression in bovine preimplantation embryos, fetal and adult tissues. Gene Expression Patterns.
3(5), 551-558.
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Jones, D. H., Golding, M. C., Barr, K. J., Fong, G. H., & Kidder, G. M.
(2001).
The mouse Na + -K + -ATPase -subunit gene (Fxyd2) encodes three developmentally regulated transcripts. Physiological Genomics.
2001(6), 129-135.
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Roach, A. N., Bhadsavle, S. S., Higgins, S. L., Derrico, D. D., Basel, A., Thomas, K. N., & Golding, M. C.
Alterations in sperm RNAs persist after alcohol cessation and correlate with epididymal mitochondrial dysfunction. 12(5), 1012-1023.
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Linger, G. D., Bormann, C. L., Peoples, M., Golding, M. C., & Long, C. R.
Expression profiling of histone-modifying genes in bovine preimplantation embryos
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Bhadsavle, S. S., Scaturro, K. Z., & Golding, M. C.
Maternal 129S1/SvImJ background attenuates the placental phenotypes induced by chronic paternal alcohol exposure
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Linger, G. D., Bormann, C. L., Peoples, M. D., Golding, M. C., & Long, C. R.
TRANSCRIPTIONAL PROFILING OF HISTONE-MODIFYING GENES DURING BOVINE PRE-IMPLANTATION EMBRYO DEVELOPMENT IN VITRO
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Golding, M. C.
Teratogenesis and the epigenetic programming of congenital defects: Why paternal exposures matter. 115(19), 1825-1834.
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Thomas, K. N., Derrico, D. D., & Golding, M. C.
(2023).
Paternal alcohol exposure and dental-facial anomalies in offspring. Reply. Journal of Clinical Investigation.
133(19), e174216.
-
conference paper
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Veazey, K. J., Skiles, W. M., Miranda, R. C., Parnell, S. E., & Golding, M. C.
AN EPIGENETIC BASIS TO THE ETIOLOGY OF FETAL ALCOHOL SPECTRUM DISORDERS. Alcoholism: Clinical and Experimental Research.
47A-47A.
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Dunlap, K. A., Simmons, R. M., Uzelac, M. G., Greff, S. M., Golding, M. C., & Satterfield, M. C.
Altered Renal Gene Expression in Both IUGR and Non-IUGR Offspring from Nutrient-Restricted Ewes. REPRODUCTIVE SCIENCES.
157A-157A.
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Thomas, K. N., Roach, A. R., Thomas, K. R., Basel, A., & Golding, M. C.
DEVELOPMENTAL TOXICITY OF DUAL PARENTAL ALCOHOL CONSUMPTION AND THE LONG-TERM EFFECTS ON OFFSPRING GROWTH, CRANIOFACIAL, AND NEUROLOGICAL DEVELOPMENT. Alcoholism: Clinical and Experimental Research.
47A-47A.
-
Golding, M. C.
HERITABLE ALTERATIONS IN CHROMATIN STRUCTURE ARISING FROM A PRENATAL ETHANOL EXPOSURE CORRELATE WITH THE DEVELOPMENT OF FAS BIRTH DEFECTS. Alcoholism: Clinical and Experimental Research.
299A-299A.
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Pinzon, C. A., Carrillo, D., Moreno, N., Saavalainen, J., Schmitz, D., Golding, M. C., Wu, J., & Long, C. R.
Harnessing a viral protein for efficient homologous recombination during mammalian genome editing. TRANSGENIC RESEARCH.
481-481.
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Long, C. R., Golding, M. C., & Westhusin, M. E.
Lentivirus mediated transgenic livestock: applications in biomedical research. TRANSGENIC RESEARCH.
192-193.
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Burroughs, C. A., Williamson, G. L., Golding, M. C., & Long, C. R.
OXIDATIVE STRESS INDUCED CHANGES IN EPIGENETIC MODIFYING GENE mRNA IN PRE-IMPLANTATION IN VITRO BOVINE EMBRYOS. Reproduction, Fertility and Development.
149-149.
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Golding, M. C.
PATERNAL ALCOHOL USE CONTRIBUTES TO FETAL ALCOHOL SPECTRUM DISORDER GROWTH & METABOLIC DEFECTS. Alcoholism: Clinical and Experimental Research.
32A-32A.
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Bedi, Y., Chang, R. C., Gibbs, R., Clement, T. M., & Golding, M. C.
PRECONCEPTION PATERNAL ALCOHOL EXPOSURE ALTERS THE SPERM NONCODING RNA CONTENT AND LEADS TO FETAL GROWTH RESTRICTION. Alcoholism: Clinical and Experimental Research.
195-195.
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Bedi, Y. S., Thomas, K. N., & Golding, M. C.
Preconception Paternal Alcohol Exposures, Epigenetic Programming of Sperm, and the Induction of Fetal-Placental Growth Defects. Birth Defects Research.
419-419.
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Williamson, G. L., Pryor, J. H., Tessanne, K., Golding, M. C., & Long, C. R.
SUPPRESSION OF Suz12 IN BOVINE PREIMPLANTATION EMBRYOS VIA CYTOPLASMIC SMALL INTERFERING RNA INJECTION. Reproduction, Fertility and Development.
200-200.
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Veazey, K. J., Skiles, W. M., Miranda, R. C., Parnell, S. E., & Golding, M. C.
AN EPIGENETIC BASIS TO THE ETIOLOGY OF FETAL ALCOHOL SPECTRUM DISORDERS. Alcoholism: Clinical and Experimental Research.
47A-47A.
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institutional repository document
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da Silveira, B. P., Kahn, S. K., Legere, R. M., Bray, J. M., Cole-Pfeiffer, H. M., Golding, M. C., Cohen, N. D., & Bordin, A. I.
Enteral immunization with live bacteria reprograms innate immune cells and protects neonatal foals from pneumonia
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da Silveira, B. P., Kahn, S. K., Legere, R. M., Bray, J. M., Cole-Pfeiffer, H. M., Golding, M. C., Cohen, N. D., & Bordin, A. I.
Enteral immunization with live bacteria reprograms innate immune cells and protects neonatal foals from pneumonia
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webpage
Research
principal investigator on
- HERITABLE, EPIGENETIC EFFECTS OF PATERNAL ALCOHOL USE ON FASD PHENOTYPES awarded by National Institute On Alcohol Abuse and Alcoholism - (Bethesda, Maryland, United States) 2020 - 2025
- To explore the mechanisms of paternal contributions to fetal alcohol spectrum disorders awarded by W. M. Keck Foundation - (Los Angeles, California, United States) 2019 - 2022
- Altered genomic imprinting as a basis for FASD placental growth defects awarded by National Institutes of Health - (Bethesda, Maryland, United States) 2014 - 2017
co-principal investigator on
Teaching
teaching activities
- BICH491 Hnr-research Instructor
- BIMS485 Directed Studies Instructor
- BIMS491 Hnr-research Instructor
- GENE491 Hnr-research Instructor
- GENE691 Research Instructor
- VTPP285 Directed Studies Instructor
- VTPP452 Fetal & Embryo Phys Instructor
- VTPP485 Directed Studies Instructor
- VTPP491 Research Instructor
- VTPP652 Fetal & Embryo Phys Instructor
- VTPP685 Directed Studies Instructor
- VTPP691 Research Instructor
Works By Students
chaired theses and dissertations
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Boone, Stephanie Rose (2017-12). Commonly Used Intra-Articular Medications Affect Bone Marrow-Derived Mesenchymal Stem Cell Growth and Viability.
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Chronister, Sarah Katherine (2016-08). Preconception Chronic Male Alcohol Exposure Induces FAS Like Growth Restriction.
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Skiles, William Mark (2017-12). Environmentally Induced Epimutations, Their Persistence, and Potential Causality in the Development of Disease in the Offspring of Exposed Individuals.
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Veazey, Kylee Jordan (2015-12). An Epigenetic Basis to the Etiology of Fetal Alcohol Spectrum Disorders.
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Wang, Haiqing (2017-04). Preconception Paternal Alcohol Exposure Disrupts Placental Gene Expression and Alters Chromatin Boundary Elements.
Background
education and training
- Ph.D. in Veterinary Physiology, Texas A&M University - (College Station, Texas, United States) 2003
awards and honors
Contact
first name
- Michael
has last name
- Golding
mailing address
-
Texas A&M University
Vet Med - Physiology & Pharmacology
4466 TAMU
College Station, TX 77843-4466
USA
Other
- mcgolding@tamu.edu