publisher of
- Paternal alcohol exposure and dental-facial anomalies in offspring. Reply.. Journal of Clinical Investigation. 133:e174216. 2023
- Adding robustness to rigor and reproducibility for the three Rs of improving translational medical research.. Journal of Clinical Investigation. 133:e173750. 2023
- Preconception paternal ethanol exposures induce alcohol-related craniofacial growth deficiencies in fetal offspring.. Journal of Clinical Investigation. 133:e167624. 2023
- Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy.. Journal of Clinical Investigation. 133:e153837. 2023
- The mRNA-binding protein DDX3 mediates TGF-1 upregulation of translation and promotes pulmonary fibrosis.. JCI INSIGHT. 8:e167566. 2023
- Mitochondrial dysfunction reactivates -fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models.. Journal of Clinical Investigation. 133:e154684. 2023
- Chronic alcohol drinking persistently suppresses thalamostriatal excitation of cholinergic neurons to impair cognitive flexibility.. Journal of Clinical Investigation. 132:e154969. 2022
- Innovations in MD-only physician-scientist training: experiences from the Burroughs Wellcome Fund physician-scientist institutional award initiative.. Journal of Clinical Investigation. 131:e149948. 2021
- Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation.. Journal of Clinical Investigation. 130:2041-2053. 2020
- Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis. 2020
- Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice.. JCI INSIGHT. 5:e131277. 2020
- Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice.. JCI INSIGHT. 4:e131692. 2019
- Stem cell-derived tissue-associated regulatory T cells suppress the activity of pathogenic cells in autoimmune diabetes.. JCI INSIGHT. 4:126471. 2019
- Ascorbic acid-induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma. 2019
- Lipoprotein lipase reaches the capillary lumen in chickens despite an apparent absence of GPIHBP1.. JCI INSIGHT. 2:e96783. 2017
- Mutations in 5-methylcytosine oxidase TET2 and RhoA cooperatively disrupt T cell homeostasis.. Journal of Clinical Investigation. 127:2998-3012. 2017
- Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.. JCI INSIGHT. 2:e90521. 2017
- RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis. 2016
- Ultrasound ablation enhances drug accumulation and survival in mammary carcinoma models.. Journal of Clinical Investigation. 126:99-111. 2016
- MicroRNA-223 is a crucial mediator of PPAR-regulated alternative macrophage activation.. Journal of Clinical Investigation. 125:4149-4159. 2015
- Phosphatidylinositol 3-kinase signaling determines kidney size.. Journal of Clinical Investigation. 125:2429-2444. 2015
- Suppression of NLRX1 in chronic obstructive pulmonary disease. 2015
- Incorporation of therapeutically modified bacteria into gut microbiota inhibits obesity. Journal of Clinical Investigation. 124:3391-3406. 2014
- Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation.. Journal of Clinical Investigation. 124:3241-3251. 2014
- BMPR2 is required for postimplantation uterine function and pregnancy maintenance. 2013
- Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK. 2013
- Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.. Journal of Clinical Investigation. 123:611-622. 2013
- Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization.. Journal of Clinical Investigation. 122:1803-1815. 2012
- Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice.. Journal of Clinical Investigation. 122:192-204. 2012
- Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. 2011
- Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.. Journal of Clinical Investigation. 119:2702-2713. 2009
- GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak.. Journal of Clinical Investigation. 118:2157-2168. 2008
- Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia. 2008
- Ghrelin promotes thymopoiesis during aging.. Journal of Clinical Investigation. 117:2778-2790. 2007
- Endocarditis and biofilm-associated pili of Enterococcus faecalis. 2006
- Response to: "Rescuing the NIH before it is too late".. Journal of Clinical Investigation. 116:1462-1463. 2006
- Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.. Journal of Clinical Investigation. 116:217-227. 2006
- Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia. 2004
- The Staphylococcus aureus Map protein is an immunomodulator that interferes with T cell-mediated responses.. Journal of Clinical Investigation. 110:1461-1471. 2002
- Proteasomal regulation of betac signaling reveals a novel mechanism for cytokine receptor heterotypic desensitization.. Journal of Clinical Investigation. 108:1797-1806. 2001
- Resistance to Lyme disease in decorin-deficient mice. 2001
- Overexpression of 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production. 2001
- Defining the atherogenicity of large and small lipoproteins containing apolipoprotein B100. 2000
- NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.. Journal of Clinical Investigation. 106:867-872. 2000
- Lipoprotein clearance mechanisms in LDL receptor-deficient "Apo-B48-only" and "Apo-B100-only" mice.. Journal of Clinical Investigation. 102:1559-1568. 1998
- Vaccination with a recombinant fragment of collagen adhesin provides protection against Staphylococcus aureus-mediated septic death.. Journal of Clinical Investigation. 101:2640-2649. 1998
- Expression of the human histocompatibility leukocyte antigen DR3 transgene reduces the severity of demyelination in a murine model of multiple sclerosis. 1998
- Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions.. Journal of Clinical Investigation. 100:1349-1362. 1997
- Kallistatin is a potent new vasodilator. 1997
- Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.. Journal of Clinical Investigation. 100:180-188. 1997
- Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor. 1997
- Inhibition of T cell apoptosis in the rheumatoid synovium. 1997
- Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/integrin interactions.. Journal of Clinical Investigation. 96:2364-2372. 1995
- Virulent strain associated outer membrane proteins of Borrelia burgdorferi.. Journal of Clinical Investigation. 96:2380-2392. 1995
- Rabbit model of Lyme borreliosis: erythema migrans, infection-derived immunity, and identification of Borrelia burgdorferi proteins associated with virulence and protective immunity. 1995
- An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance. 1995
- Phenotypic variability and incomplete penetrance of spontaneous fractures in an inbred strain of transgenic mice expressing a mutated collagen gene (COL1A1). 1994
- Mechanical strain and collagen potentiate mitogenic activity of angiotensin II in rat vascular smooth muscle cells. 1993
- Renal ammonia and glutamine metabolism during liver insufficiency-induced hyperammonemia in the rat.. Journal of Clinical Investigation. 92:2834-2840. 1993
- An inbred line of transgenic mice expressing an internally deleted gene for type II procollagen (COL2A1). Young mice have a variable phenotype of a chondrodysplasia and older mice have osteoarthritic changes in joints.. Journal of Clinical Investigation. 92:582-595. 1993
- Sequencing of cDNA from 50 unrelated patients reveals that mutations in the triple-helical domain of type III procollagen are an infrequent cause of aortic aneurysms. 1993
- Transgenic mice expressing a partially deleted gene for type I procollagen (COL1A1). A breeding line with a phenotype of spontaneous fractures and decreased bone collagen and mineral.. Journal of Clinical Investigation. 91:709-716. 1993
- Genetic causes of aortic aneurysms. Unlearning at least part of what the textbooks say.. Journal of Clinical Investigation. 88:1441-1444. 1991
- A mutation in the gene for type III procollagen (COL3A1) in a family with aortic aneurysms. 1990
- A lethal variant of osteogenesis imperfecta has a single base mutation that substitutes cysteine for glycine 904 of the alpha 1(I) chain of type I procollagen. The asymptomatic mother has an unidentified mutation producing an overmodified and unstable type I procollagen.. Journal of Clinical Investigation. 83:574-584. 1989
- Lysine and protein metabolism in young women. Subdivision based on the novel use of multiple stable isotopic labels. 1986
- Postnatal development of alveoli. Regulation and evidence for a critical period in rats.. Journal of Clinical Investigation. 76:1297-1305. 1985
- Modulation of procollagen gene expression by retinoids. Inhibition of collagen production by retinoic acid accompanied by reduced type I procollagen messenger ribonucleic acid levels in human skin fibroblast cultures.. Journal of Clinical Investigation. 75:1545-1553. 1985
- Mutations in collagen genes. Consequences for rare and common diseases.. Journal of Clinical Investigation. 75:783-787. 1985
- Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta.. Journal of Clinical Investigation. 72:1262-1267. 1983
- Prevention of collagen deposition following pulmonary oxygen toxicity in the rat by cis-4-hydroxy-L-proline.. Journal of Clinical Investigation. 65:643-651. 1980
- Collagen degradation and the response to parathyroid extract in the intact rhesus monkey.. Journal of Clinical Investigation. 46:217-224. 1967
- ISOTOPIC STUDIES ON COLLAGEN DEGRADATION AND THE URINE EXCRETION OF HYDROXYPROLINE.. Journal of Clinical Investigation. 43:453-460. 1964
- Isotopic Studies on Collagen Degradation and the Urine Excretion of Hydroxyproline *. Journal of Clinical Investigation. 43:453-460. 1964
- Significance of urinary hydroxyproline in man.. Journal of Clinical Investigation. 40:843-849. 1961