Martinez-Moczygemba, Margarita Research Associate Professor

The research focus of the Moczygemba laboratory is to develop interventional strategies that block allergic inflammation through our increased understanding of cytokine signaling and eosinophil biology. The eosinophil and its major activator, IL-5, play an important role in the pathogenesis of allergies and asthma. Thus, one of our goals is to understand regulatory mechanisms that control the intensity and duration of IL-5-mediated eosinophilic signaling. To this end, we employ various cellular, immunological, and biochemical techniques to help us identify novel targets capable of modulating inflammatory signals triggered by eosinophils.