Adherence to pharmacological interventions. Current trends and future directions. The Pharmacological Intervention Working Group. Academic Article uri icon


  • The complexity of adherence to pharmacological interventions is frequently underestimated. Consequently, little research has been done to understand, improve, or evaluate the effects of adherence to drug protocols. While efforts to better measure and increase adherence require dedicated resources, improved adherence in existing clinical research can potentially cut costs in trial size and length. This paper outlines strategies to facilitate research on adherence to pharmacological interventions including: reporting of adherence data, changing how we conceptualize adherence to pharmaceuticals, understanding issues unique to older adults' pill-taking behavior, and creating standardized methodologies to measure adherence. Further, we describe some promising research areas that may lead to effective interventions: adherence "typologies" and modality matching. Control Clin Trials 2000;21:218S-225S

published proceedings

  • Control Clin Trials

author list (cited authors)

  • Ellis, S., Shumaker, S., Sieber, W., & Rand, C.

citation count

  • 41

complete list of authors

  • Ellis, S||Shumaker, S||Sieber, W||Rand, C

publication date

  • October 2000