A novel computer-controlled conditioned avoidance apparatus for rats. Academic Article

abstract

• Described and evaluated here is a newly designed apparatus for the assessment of conditioned avoidance response (CAR) performance in rats. The system is computer-assisted using a design and system control development package based on the virtual instrument concept (LabView). The program, which allows for significant flexibility, greatly facilitated and simplified the process of timing and data acquisition. The apparatus was found effective and appropriately designed for CAR performance training, as well as for a reliable assessment of the effects of antipsychotic and potentially antipsychotic compounds on CAR in rats. The design presents a new, effective, and inexpensive option for laboratories involved in animal behavioral research.

authors

• Hicks, Paul
• Young, Keith

published proceedings

• J Pharmacol Toxicol Methods

author list (cited authors)

• Wadenberg, M. L., Young, K. A., Trompler, R. A., Zavodny, R. A., Richter, T. J., & Hicks, P. B.

citation count

• 18

complete list of authors

• Wadenberg, ML||Young, KA||Trompler, RA||Zavodny, RA||Richter, TJ||Hicks, PB

publication date

• January 1997

publisher

• Elsevier  Publisher

published in

• Journal of Pharmacological and Toxicological Methods  Journal

keywords

• Amphetamines
• Animals
• Antipsychotic Agents
• Avoidance Learning
• Benzazepines
• Clozapine
• Computers
• Cross-Over Studies
• Dopamine Antagonists
• Fluorobenzenes
• Haloperidol
• Male
• Physical Conditioning, Animal
• Piperidines
• Raclopride
• Rats
• Rats, Sprague-Dawley
• Salicylamides
• Serotonin Antagonists
• Serotonin Receptor Agonists

PubMed Central ID

• 9566445

Digital Object Identifier (DOI)

• 10.1016/s1056-8719(97)00104-4

start page

• 211

end page

• 215

volume

• 38

issue

• 4

URL

• http://dx.doi.org/10.1016/s1056-8719(97)00104-4