Potential use of stem cells from bone marrow to repair the extracellular matrix and the central nervous system. Academic Article

abstract

• A subset of stem-like cells from bone marrow that are referred to as marrow stromal cells (MSCs) have been shown to be capable of differentiating into osteoblasts, chondrocytes, adipocytes, myocytes, astrocytes and perhaps neurons. Recently, conditions have been developed where human MSCs can be expanded almost without limit in culture without apparently losing their multipotentiality for differentiation. The cells appear to be potentially useful for the repair of extracellular matrix and the central nervous system.

authors

• Prockop, Darwin

published proceedings

• Biochem Soc Trans

altmetric score

• 3

author list (cited authors)

• Prockop, D. J., Azizi, S. A., Colter, D., Digirolamo, C., Kopen, G., & Phinney, D. G.

citation count

• 29

complete list of authors

• Prockop, DJ||Azizi, SA||Colter, D||Digirolamo, C||Kopen, G||Phinney, DG

publication date

• January 2000

publisher

• Portland Press  Publisher

published in

• Biochemical Society Transactions  Journal

keywords

• Animals
• Bone Diseases
• Bone Marrow Cells
• Brain
• Cell Differentiation
• Cells, Cultured
• Central Nervous System
• Central Nervous System Diseases
• Extracellular Matrix
• Female
• Humans
• In Situ Hybridization, Fluorescence
• Mice
• Mice, Transgenic
• Muscular Diseases
• Neurons
• Rats
• Stem Cells

Digital Object Identifier (DOI)

• 10.1042/bst0280341

start page

• 341

end page

• 345

volume

• 28

issue

• 4

URL

• http://dx.doi.org/10.1042/bst0280341