HR job title
- Assistant Professor
- Contact Info
- ORCiD
- 0000-0002-8248-2888
George, Jason Assistant Professor
Positions
- Assistant Professor, Biomedical Engineering, College of Engineering
- Overview
- Publications
- Teaching
- Contact
- Other
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Overview
Publications
selected publications
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academic article
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Wang, A., Lin, X., Chau, K. N., Onuchic, J. N., Levine, H., & George, J. T.
(2024).
RACER-m leverages structural features for sparse T cell specificity prediction. Science Advances.
10(20), eadl0161.
-
Najafi, A., Jolly, M. K., & George, J. T.
(2024).
Protocol for inferring epithelial-to-mesenchymal transition trajectories from single-cell RNA sequencing data using R. STAR Protocols.
5(1), 102819.
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George, J. T.
(2023).
Optimal phenotypic adaptation in fluctuating environments. Biophysical Journal.
122(22), 4414-4424.
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Najafi, A., Jolly, M. K., & George, J. T.
(2023).
Population dynamics of EMT elucidates the timing and distribution of phenotypic intra-tumoral heterogeneity. iScience.
26(7), 106964-106964.
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George, J. T., & Levine, H.
(2023).
Optimal cancer evasion in a dynamic immune microenvironment generates diverse post-escape tumor antigenicity profiles. eLife.
12, e82786.
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Najafi, A., Jolly, M. K., & George, J. T.
(2023).
Abstract 1231: A stochastic data-driven model predicts the timing and distribution of the epithelial-mesenchymal transition. Cancer Research.
83(7_Supplement), 1231-1231.
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Chau, K. N., George, J. T., Onuchic, J. N., Lin, X., & Levine, H.
(2023).
Contact map dependence of a T-cell receptor binding repertoire. 122(3), 271a-272a.
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Jain, P., Corbo, S., Mohammad, K., Sahoo, S., Ranganathan, S., George, J. T., ... Jolly, M. K.
(2023).
Epigenetic memory acquired during long-term EMT induction governs the recovery to the epithelial state. Journal of the Royal Society Interface.
20(198), 20220627.
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Ng Chau, K., George, J. T., Onuchic, J. N., Lin, X., & Levine, H.
(2022).
Contact map dependence of a T-cell receptor binding repertoire. Physical Review E.
106(1-1), 014406.
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Masuda, H., Harano, K., Miura, S., Wang, Y., Hirota, Y., Harada, O. i., ... Ueno, N. T.
(2022).
Changes in Triple-Negative Breast Cancer Molecular Subtypes in Patients Without Pathologic Complete Response After Neoadjuvant Systemic Chemotherapy. JCO Precision Oncology.
6(6), e2000368.
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Mandal, S., Tejaswi, T., Janivara, R., Srikrishnan, S., Thakur, P., Sahoo, S., ... Jolly, M. K.
(2021).
Transcriptomic-Based Quantification of the Epithelial-Hybrid-Mesenchymal Spectrum across Biological Contexts. Biomolecules.
12(1), 29-29.
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Lin, X., George, J. T., Schafer, N. P., Chau, K. N., Birnbaum, M. E., Clementi, C., Onuchic, J. N., & Levine, H.
(2021).
Rapid Assessment of T-Cell Receptor Specificity of the Immune Repertoire. 1(5), 362-373.
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Chakraborty, P., George, J. T., Woodward, W. A., Levine, H., & Jolly, M. K.
(2021).
Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum. Transl Oncol.
14(4), 101026-101026.
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George, J. T., & Levine, H.
(2021).
Implications of Tumor-Immune Coevolution on Cancer Evasion and Optimized Immunotherapy. 7(4), 373-383.
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Thankamony, A. P., Murali, R., Karthikeyan, N., Varghese, B. A., Teo, W. S., McFarland, A., ... Nair, R.
(2020).
Targeting the Id1-Kif11 Axis in Triple-Negative Breast Cancer Using Combination Therapy. Biomolecules.
10(9), 1295-1295.
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George, J. T., Garber, H. R., Molldrem, J. J., & Levine, H.
(2020).
Abstract B59: Co-evolution between tumor cells and immune system in the setting of T-cell immunotherapy. CANCER IMMUNOLOGY RESEARCH.
8(4_Supplement), b59-b59.
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George, J. T., & Levine, H.
(2020).
Abstract A104: A stochastic model of tumor-immune evasion predicts sustained coevolution and tumor antigen downregulation. 8(3_Supplement), a104-a104.
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George, J. T., & Levine, H.
(2020).
Sustained Coevolution in a Stochastic Model of Cancer-Immune Interaction. 80(4), 811-819.
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Nihan Kilinc, A., Sugiyama, N., Reddy Kalathur, R. K., Antoniadis, H., Birogul, H., Ishay-Ronen, D., ... Christofori, G.
(2020).
Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial-mesenchymal plasticity and tumor metastasis. Oncogene.
39(7), 1498-1513.
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Lourenco, A. R., Ban, Y. i., Crowley, M. J., Lee, S. B., Ramchandani, D., Du, W., ... Gao, D.
(2020).
Differential Contributions of Pre- and Post-EMT Tumor Cells in Breast Cancer Metastasis. Cancer Research.
80(2), 163-169.
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Chakraborty, P., George, J. T., Tripathi, S., Levine, H., & Jolly, M. K.
(2020).
Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum. Frontiers in Bioengineering and Biotechnology.
8, 220.
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Thangavel, H., De Angelis, C., Vasaikar, S., Bhat, R., Jolly, M. K., Nagi, C., ... Trivedi, M. V.
(2019).
A CTC-Cluster-Specific Signature Derived from OMICS Analysis of Patient-Derived Xenograft Tumors Predicts Outcomes in Basal-Like Breast Cancer. Journal of Clinical Medicine.
8(11), 1772-1772.
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George, J. T., Molldrem, J. J., & Levine, H.
(2019).
Abstract 1195: Stochastic co-evolution of the adaptive immune system and an evading cancer population. Cancer Research.
79(13_Supplement), 1195-1195.
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Thangavel, H., Angelis, C. D., Vasaikar, S., Bhat, R., Jolly, M. K., Dobrolecki, L. E., ... Trivedi, M. V.
(2019).
Abstract 2783: OMICS analysis of breast cancer PDX tumors to determine CTC-cluster-specific signature in predicting breast cancer metastasis. Cancer Research.
79(13_Supplement), 2783-2783.
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Jolly, M. K., Ware, K. E., Xu, S., Gilja, S., Shetler, S., Yang, Y., ... Somarelli, J. A.
(2019).
E-Cadherin Represses Anchorage-Independent Growth in Sarcomas through Both Signaling and Mechanical Mechanisms. 17(6), 1391-1402.
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Bocci, F., Tripathi, S. C., Vilchez Mercedes, S. A., George, J. T., Casabar, J. P., Wong, P. K., ... Jolly, M. K.
(2019).
NRF2 activates a partial epithelial-mesenchymal transition and is maximally present in a hybrid epithelial/mesenchymal phenotype. Integrative Biology: interdisciplinary approaches for molecular and cellular life sciences.
11(6), 251-263.
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George, J. T., Levine, H., Molldrem, J. J., & Garber, H.
(2019).
Stochastic cancer-immune coevolution: Implications for cancer incidence and immunotherapeutic efficacy. Journal of Clinical Oncology.
37(15_suppl), e14023-e14023.
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Shinde, A., Hardy, S. D., Kim, D., Akhand, S. S., Jolly, M. K., Wang, W., ... Wendt, M. K.
(2019).
Spleen Tyrosine Kinase-Mediated Autophagy Is Required for Epithelial-Mesenchymal Plasticity and Metastasis in Breast Cancer. Cancer Research.
79(8), 1831-1843.
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Li, X., Jolly, M. K., George, J. T., Pienta, K. J., & Levine, H.
(2019).
Computational Modeling of the Crosstalk Between Macrophage Polarization and Tumor Cell Plasticity in the Tumor Microenvironment. Frontiers in Oncology.
9, 10.
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Jia, D., George, J. T., Tripathi, S. C., Kundnani, D. L., Lu, M., Hanash, S. M., ... Levine, H.
(2019).
Testing the gene expression classification of the EMT spectrum. Physical Biology.
16(2), 025002-025002.
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George, J. T., & Levine, H.
(2018).
Stochastic modeling of tumor progression and immune evasion. Journal of Theoretical Biology.
458, 148-155.
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Jolly, M. K., Preca, B., Tripathi, S. C., Jia, D., George, J. T., Hanash, S. M., ... Levine, H.
(2018).
Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer. APL Bioengineering.
2(3), 031908-031908.
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Bocci, F., Jolly, M. K., George, J. T., Levine, H., & Onuchic, J. N.
(2018).
A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signaling. Oncotarget.
9(52), 29906-29920.
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George, J. T., Jolly, M. K., Xu, S., Somarelli, J. A., & Levine, H.
(2017).
Survival Outcomes in Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric. 77(22), 6415-6428.
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George, J. T., Kessler, D. A., & Levine, H.
(2017).
Effects of thymic selection on T cell recognition of foreign and tumor antigenic peptides. Proceedings of the National Academy of Sciences of the United States of America.
114(38), E7875-E7881.
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George, J. T., Jolly, M. K., & Levine, H.
(2017).
Abstract 563: Quantitative EMT expression score for predicting survival outcome. Cancer Research.
77(13_Supplement), 563-563.
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Fei, R., George, J. T., Park, J., Means, A. K., & Grunlan, M. A.
(2013).
Ultra-strong thermoresponsive double network hydrogels. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
9(10), 2912-2919.
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Fei, R., George, J. T., Park, J., Means, A. K., & Grunlan, M. A.
(2013).
Ultra-strong thermoresponsive double network hydrogels. SOFT MATTER.
9(10), 2912-2919.
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Fei, R., George, J. T., Park, J., & Grunlan, M. A.
(2012).
Thermoresponsive nanocomposite double network hydrogels. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
8(2), 481-487.
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Fei, R., George, J. T., Park, J., & Grunlan, M. A.
(2012).
Thermoresponsive nanocomposite double network hydrogels. SOFT MATTER.
8(2), 481-487.
-
Wang, A., Lin, X., Chau, K. N., Onuchic, J. N., Levine, H., & George, J. T.
(2024).
RACER-m leverages structural features for sparse T cell specificity prediction. Science Advances.
10(20), eadl0161.
-
conference paper
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George, J. T.
(2022).
Stochastic modeling uncovers the interplay between early cancer progression and adaptive immune-specific cancer escape. Cancer Research.
-
Thangavel, H., Angelis, C. D., Vasaikar, S., Bhat, R., Jolly, M. K., Dobrolecki, L. E., ... Trivedi, M. V.
(2019).
Abstract 2783: OMICS analysis of breast cancer PDX tumors to determine CTC-cluster-specific signature in predicting breast cancer metastasis. 2783-2783.
-
Grunlan, M. A., Fei, R., George, J. T., & Means, A. K.
(2013).
High strength thermoresponsive double network hydrogels. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
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George, J. T., Fei, R., Park, J. T., & Grunlan, M. A.
(2012).
Thermoresponsive double network hydrogels with improved mechanical properties. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
-
George, J. T.
(2022).
Stochastic modeling uncovers the interplay between early cancer progression and adaptive immune-specific cancer escape. Cancer Research.
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institutional repository document
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Fan, Y., & George, J. T.
(2024).
Distinct evolutionary patterns of tumor immune escape and elimination determined by ECM architectures
-
Wang, A., Lin, X., Chau, K. N., Onuchic, J. N., Levine, H., & George, J. T.
(2023).
RACER-m Leverages Structural Features for Sparse T Cell Specificity Prediction
-
George, J. T.
(2023).
Optimal Cellular Phenotypic Adaptation in Fluctuating Environments
-
Najafi, A., Jolly, M. K., & George, J. T.
(2023).
Population Dynamics of EMT Elucidates the Timing and Distribution of Phenotypic Intra-tumoral Heterogeneity
-
Jain, P., Corbo, S., Mohammad, K., George, J. T., Levine, H., Toneff, M., & Jolly, M. K.
(2022).
Epigenetic memory acquired during long-term EMT induction governs the recovery to the epithelial state
-
George, J. T., & Levine, H.
(2022).
Optimal Cancer Evasion in a Dynamic Immune Microenvironment
-
Chau, K. N., George, J. T., Onuchic, J. N., Lin, X., & Levine, H.
(2021).
Contact map dependence of a T cell receptor binding repertoire
-
Mandal, S., Tejaswi, T., Janivara, R., Srikrishnan, S., Thakur, P., Sahoo, S., ... Jolly, M. K.
(2021).
Transcriptomic-based quantification of the epithelial-hybrid-mesenchymal spectrum across biological contexts
-
Chakraborty, P., George, J. T., Woodward, W. A., Levine, H., & Jolly, M. K.
(2020).
Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum
-
Lin, X., George, J. T., Schafer, N. P., Chau, K. N., Birnbaum, M. E., Clementi, C., Onuchic, J. N., & Levine, H.
(2020).
Rapid Assessment of T-Cell Receptor Specificity of the Immune Repertoire
-
Chakraborty, P., George, J. T., Tripathi, S., Levine, H., & Jolly, M. K.
(2020).
Comparative study of transcriptomics-based scoring metrics for the epithelial-hybrid-mesenchymal spectrum
-
Murali, R., Varghese, B. A., Karthikeyan, N., Archana, P. T., Teo, W. S., McFarland, A., ... Nair, R.
(2019).
Targeting the Id1-Kif11-Aurka axis in triple negative breast cancer using combination therapy
-
George, J. T., & Levine, H.
(2019).
Sustained Co-evolution in a Stochastic Model of the Cancer-Immune Interaction
-
Jia, D., George, J. T., Tripathi, S. C., Kundnani, D. L., Lu, M., Hanash, S. M., ... Levine, H.
(2018).
Testing the Gene Expression Classification of the EMT Spectrum
-
Li, X., Jolly, M. K., George, J. T., Pienta, K. J., & Levine, H.
(2018).
Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment
-
Bocci, F., Tripathi, S. C., Mercedes, S., George, J. T., Casabar, J. P., Wong, P. K., ... Jolly, M. K.
(2018).
NRF2 activates a partial Epithelial-Mesenchymal Transition and is maximally present in a hybrid Epithelial/Mesenchymal phenotype
-
Jolly, M. K., Ware, K. E., Xu, S., Gilja, S., Shetler, S., Yang, Y., ... Somarelli, J. A.
(2018).
E-cadherin represses anchorage-independent growth in sarcomas through both signaling and mechanical mechanisms
-
Bocci, F., Jolly, M. K., George, J., Levine, H., & Onuchic, J. N.
(2018).
A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signaling
-
Villela-Castrejon, J., Levine, H., Onuchic, J. N., George, J. T., & Jia, D.
Computational modeling of cancer cell metabolism along the catabolic-anabolic axes
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Teimouri, H., Ghoreyshi, Z. S., Kolomeisky, A. B., & George, J. T.
Feature Selection Enhances Peptide Binding Predictions for TCR-Specific Interactions
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Shrestha, P., Ghoreyshi, Z. S., & George, J. T.
How Modulation of the Tumor Microenvironment Drives Cancer Immune Escape Dynamics
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Ghoreyshi, Z. S., Teimouri, H., Kolomeisky, A. B., & George, J. T.
Integration of Kinetic Data into Affinity-Driven Models for Improved T Cell-Antigen Specificity Prediction
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Fan, Y., & George, J. T.
(2024).
Distinct evolutionary patterns of tumor immune escape and elimination determined by ECM architectures
Teaching
teaching activities
- BMEN341 Biofluid Mechanics Instructor
- BMEN341 Biotransport Instructor
- BMEN491 Hnr-research Instructor
- BMEN689 Sptp: Stochastic Model & Math Instructor
- BMEN691 Research Instructor
Contact
first name
- Jason
has last name
- George
Other
- jason.george@tamu.edu