An expression system for Gustatory receptorsAnd why it failed
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A recent paper by the Dahankuar laboratory suggested that single Drosophila sugar receptors proteins accurately mediate sugar detection when ectopically expressed in olfactory neurons of the antenna. These findings contra-dict numerous previously published electrophysiological and behavioral investigations, which all point towards heteromultimeric sugar taste receptors. Here, I provide some explanation why this pseudo-heterologous expression system may have led to this misleading conclusion. 2014 Taylor & Francis Group, LLC.
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