An expression system for Gustatory receptorsAnd why it failed Academic Article

abstract

• A recent paper by the Dahankuar laboratory suggested that single Drosophila sugar receptors proteins accurately mediate sugar detection when ectopically expressed in olfactory neurons of the antenna. These findings contra-dict numerous previously published electrophysiological and behavioral investigations, which all point towards heteromultimeric sugar taste receptors. Here, I provide some explanation why this pseudo-heterologous expression system may have led to this misleading conclusion. 2014 Taylor & Francis Group, LLC.

authors

• Amrein, Hubert

published proceedings

• Fly

author list (cited authors)

• Amrein, H.

citation count

• 2

complete list of authors

• Amrein, Hubert

publication date

• 2015

keywords

• Animals
• Drosophila
• Expression System
• Gr Genes
• Heterodimers
• Olfactony Learning And Memory
• Olfactory Neuron
• Receptors, Cell Surface
• Taste
• Taste Buds
• Taste Receptors

PubMed Central ID

• 25975755

Digital Object Identifier (DOI)

• 10.1080/19336934.2015.1039756

start page

• 232

end page

• 233

volume

• 8

issue

• 4

URL

• http://dx.doi.org/10.1080/19336934.2015.1039756