Suppression of male courtship by a Drosophila pheromone receptor.

abstract

• In male Drosophila, chemosensory cues control many aspects of social behavior. We found that males with a mutated Gustatory receptor 32a gene (Gr32a) show high courtship toward males and mated females, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone. Notably, we discovered that tarsal Gr32a-expressing neurons were essential for courtship suppression and projected to the ventrolateral protocerebrum, implying direct communication of chemosensory neurons with a higher-order brain structure.

authors

• Amrein, Hubert
• Miyamoto, Tetsuya

published proceedings

• Nat Neurosci

altmetric score

• 3

author list (cited authors)

• Miyamoto, T., & Amrein, H.

citation count

• 167

complete list of authors

• Miyamoto, Tetsuya||Amrein, Hubert

publisher

• Springer Nature  Publisher

published in

• Nature Neuroscience  Journal

keywords

• Animals
• Animals, Genetically Modified
• Courtship
• Drosophila Melanogaster
• Drosophila Proteins
• Extremities
• Female
• Gene Targeting
• Inhibition, Psychological
• Male
• Neurons
• Receptors, Cell Surface
• Receptors, Pheromone
• Sexual Behavior, Animal
• Video Recording

PubMed Central ID

• 18641642

Digital Object Identifier (DOI)

• 10.1038/nn.2161

start page

• 874

end page

• 876

volume

• 11

issue

• 8

URL

• http://dx.doi.org/10.1038/nn.2161