Physiology and pathobiology of the microcirculation. Academic Article

abstract

• The delivery of nutrients to the tissues and the removal of waste products from the tissues is made possible by forcing a stream of blood through an arborizing network of microscopic blood vessels that comprise the microcirculation. The rapidity of the flow stream and, therefore, the rate of nutrient delivery to the tissue, is regulated by the automatic adjustment of the caliber of the precapillary arterioles that serve as the primary loci of vascular resistance. Exchange between the blood stream and the parenchymal cells occurs in capillaries and pericytic venules. Pathologic processes such as inflammation, diabetes, ischemia, and hypertension are characterized by abnormalities in microvascular structure and function.

authors

• Meininger, Cynthia
• Zawieja, David

published proceedings

• Am J Otolaryngol

author list (cited authors)

• Granger, H. J., Schelling, M. E., Lewis, R. E., Zawieja, D. C., & Meininger, C. J.

citation count

• 12

complete list of authors

• Granger, HJ||Schelling, ME||Lewis, RE||Zawieja, DC||Meininger, CJ

publication date

• November 1988

publisher

• Elsevier  Publisher

published in

• American Journal of Otolaryngology: Head and Neck Medicine and Surgery  Journal

keywords

• Animals
• Capillary Permeability
• Homeostasis
• Humans
• Microcirculation
• Vascular Diseases

PubMed Central ID

• 3067590

Digital Object Identifier (DOI)

• 10.1016/s0196-0709(88)80035-8

start page

• 264

end page

• 277

volume

• 9

issue

• 6

URL

• http://dx.doi.org/10.1016/s0196-0709(88)80035-8