Probing the role of sigma interaction and energetics in the catalytic efficiency of endo-1,4--xylanase. Academic Article uri icon


  • Chaetomium globosum endo-1,4--xylanase (XylCg) is distinguished from other xylanases by its high turnover rate (1,860 s(-1)), the highest ever reported for fungal xylanases. One conserved amino acid, W48, in the substrate binding pocket of wild-type XylCg was identified as an important residue affecting XylCg's catalytic efficiency.

published proceedings

  • Appl Environ Microbiol

author list (cited authors)

  • Singh, R. K., Tiwari, M. K., Kim, I., Chen, Z., & Lee, J.

citation count

  • 8

complete list of authors

  • Singh, Raushan Kumar||Tiwari, Manish Kumar||Kim, In-Won||Chen, Zhilei||Lee, Jung-Kul

publication date

  • December 2012