Neural stem cell therapy for temporal lobe epilepsy

abstract

• SummaryNeural stem cells (NSCs) are one of the candidates for grafting in the realm of cellbased therapy for temporal lobe epilepsy (TLE). Because NSCs can produce neurons synthesizing the inhibitory neurotransmitter aminobutyric acid (GABA) and cells secreting multiple neurotrophic factors, NSC grafting therapy has promise for restraining seizures and easing cognitive dysfunction in TLE. For an expanded treatment of this topic see Jaspers Basic Mechanisms of the Epilepsies, Fourth Edition (Noebels JL, Avoli M, Rogawski MA, Olsen RW, DelgadoEscueta AV, eds) published by Oxford University Press (available on the National Library of Medicine Bookshelf [NCBI] at http://www.ncbi.nlm.nih.gov/books).

authors

• Shetty, Ashok

published proceedings

• EPILEPSIA

author list (cited authors)

• Shetty, A. K.

citation count

• 4

complete list of authors

• Shetty, Ashok K

publication date

• December 2010

publisher

• Wiley  Publisher

published in

• EPILEPSIA  Journal

keywords

• GABA
• Glial-derived Neurotrophic Factor
• Hippocampus
• Seizures
• Transplantation

Digital Object Identifier (DOI)

• 10.1111/j.1528-1167.2010.02878.x

start page

• 92

end page

• 92

volume

• 51

issue

• s5

URL

• https://doi.org/10.1111/j.1528-1167.2010.02878.x