Metastatic potential as a heritable trait.

abstract

• Cancer metastasis has historically been viewed in the context of the mutational spectra arising during development of the primary cancer. The identification of a new modifier of cancer metastasis efficiency in mice provides experimental support for a predisposition model in which metastatic potential is viewed as a heritable trait influenced by host genetic polymorphisms. 2005 Nature Publishing Group.

authors

• Threadgill, David

published proceedings

• Nat Genet

author list (cited authors)

• Threadgill, D. W.

citation count

• 12

complete list of authors

• Threadgill, David W

publication date

• October 2005

publisher

• Springer Nature  Publisher

published in

• Nature Genetics  Journal

keywords

• Animals
• Disease Models, Animal
• Genetic Predisposition To Disease
• Humans
• Mice
• Neoplasm Metastasis
• Neoplasms
• Polymorphism, Genetic

PubMed Central ID

• 16195717

Digital Object Identifier (DOI)

• 10.1038/ng1005-1026

start page

• 1026

end page

• 1027

volume

• 37

issue

• 10

URL

• https://doi.org/10.1038/ng1005-1026