The nature and identification of quantitative trait loci: a community's view. Academic Article uri icon

abstract

  • This white paper by eighty members of the Complex Trait Consortium presents a community's view on the approaches and statistical analyses that are needed for the identification of genetic loci that determine quantitative traits. Quantitative trait loci (QTLs) can be identified in several ways, but is there a definitive test of whether a candidate locus actually corresponds to a specific QTL?

published proceedings

  • Nat Rev Genet

altmetric score

  • 8.85

author list (cited authors)

  • Abiola, O., Angel, J. M., Avner, P., Bachmanov, A. A., Belknap, J. K., Bennett, B., ... Complex Trait Consortium.

citation count

  • 354

complete list of authors

  • Abiola, Oduola||Angel, Joe M||Avner, Philip||Bachmanov, Alexander A||Belknap, John K||Bennett, Beth||Blankenhorn, Elizabeth P||Blizard, David A||Bolivar, Valerie||Brockmann, Gundrun A||Buck, Kari J||Bureau, Jean-Francoise||Casley, William L||Chesler, Elissa J||Cheverud, James M||Churchill, Gary A||Cook, Melloni||Crabbe, John C||Crusio, Wim E||Darvasi, Ariel||de Haan, Gerald||Dermant, Peter||Doerge, RW||Elliot, Rosemary W||Farber, Charles R||Flaherty, Lorraine||Flint, Jonathan||Gershenfeld, Howard||Gibson, John P||Gu, Jing||Gu, Weikuan||Himmelbauer, Heinz||Hitzemann, Robert||Hsu, Hui-Chen||Hunter, Kent||Iraqi, Fuad F||Jansen, Ritsert C||Johnson, Thomas E||Jones, Byron C||Kempermann, Gerd||Lammert, Frank||Lu, Lu||Manly, Kenneth F||Matthews, Douglas B||Medrano, Juan F||Mehrabian, Margarete||Mittlemann, Guy||Mock, Beverly A||Mogil, Jeffrey S||Montagutelli, Xavier||Morahan, Grant||Mountz, John D||Nagase, Hiroki||Nowakowski, Richard S||O'Hara, Bruce F||Osadchuk, Alexander V||Paigen, Beverly||Palmer, Abraham A||Peirce, Jeremy L||Pomp, Daniel||Rosemann, Michael||Rosen, Glenn D||Schalkwyk, Leonard C||Seltzer, Ze'ev||Settle, Stephen||Shimomura, Kazuhiro||Shou, Siming||Sikela, James M||Siracusa, Linda D||Spearow, Jimmy L||Teuscher, Cory||Threadgill, David W||Toth, Linda A||Toye, Ayo A||Vadasz, Csaba||Van Zant, Gary||Wakeland, Edward||Williams, Robert W||Zhang, Huang-Ge||Zou, Fei

publication date

  • November 2003